Prostaglandins and medicine最新文献_第10页

Instability of 6-keto-prostaglandin Fα when subjected to normal extraction procedures 6-酮-前列腺素Fα在正常提取过程中的不稳定性

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90076-8

M.D. Mitchell, J.D. Brunt, R. Webb

引用次数: 13

Effect of prolonged exercise on plasma prostaglandin levels 长时间运动对血浆前列腺素水平的影响

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90073-2

Laurence M. Demers, Timothy S. Harrison, David R. Halbert, Richard J. Santen

引用次数: 99

The effect of intravenous prostacyclin on resting pains and healing of ischaemic ulcers in peripheral artery disease 静脉注射前列环素对外周动脉疾病缺血性溃疡静息痛及愈合的影响

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90064-1

Anders G. Olsson, Erling Nilsson

引用次数: 17

Methyl ethers of prostaglandins F2α and I2 前列腺素F2α和I2的甲基醚

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90066-5

Niels H. Andersen, N. Subramanian, Biswanath De, David A. McCrae, Sara S. Tynan, Ch.V. Rao

引用次数: 4

Effects of prostaglandins E1 and E2 on the in vitro production of immunoglobulin by human peripheral blood lymphocytes 前列腺素E1和E2对人外周血淋巴细胞体外产生免疫球蛋白的影响

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90074-4

J.V. Dunnes, B. Foss, T. Leung, R.J.R. McKendry

引用次数: 7

The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia 使用-亚麻酸和亚油酸来区分颞叶癫痫和精神分裂症

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90069-0

K.S. Vaddadi

引用次数: 42

Cervical dilatation in late first trimester termination by prostaglandin, hylase and isogel 前列腺素、羟化酶和等凝胶在妊娠晚期终止宫颈扩张中的作用

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90070-7

A.V. Mandlekar, A.C. Ganguli, U.R. Krishna, V.N. Purandare

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引用次数: 1

The metabolism of prostaglandin E2 is decreased by sulfinpyrazone in isolated hamster lungs 磺胺吡嗪能降低离体仓鼠肺中前列腺素E2的代谢

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90077-X

Pekka Uotila

{"title":"The metabolism of prostaglandin E2 is decreased by sulfinpyrazone in isolated hamster lungs","authors":"Pekka Uotila","doi":"10.1016/0161-4630(81)90077-X","DOIUrl":"10.1016/0161-4630(81)90077-X","url":null,"abstract":"<div>The metabolism of prostaglandin E2 (PGE2) was decreased in isolated male hamster lungs, when sulfinpyrazone was infused into the pulmonary circulation. After pulmonary injection of 20 nmol of14C-PGE2 the amount of 15-keto-metabolites of PGE2 was in the effluent from control lungs 4.0 ± 0.5 nmol (mean ± SEM) and in those from 20 μM and 100 μM sulfinpyrazone treated lungs 1.9 ± 0.2 nmol (2P<0.01 compared to the control) and 1.7 ± 0.4 nmol (2P <0.01), respectively.The amount of unmetabolized PGE2 was correspondingly increased in the effluent by sulfinpyrazone. The rate of efflux of the radioactivity from the lungs was increased by sulfinpyrazone. After injection of 10 nmol of 14C-PGE2 into the pulmonary circulation half of the injected radioactivity appeared in the effluent in 30 ± 4 sec in control and in 15 ± 0.7 sec (2P <0·01) in 20 μM sulfinpyrazone experiments. Sulfinpyrazone had no effect on the activity of 15-hydroxyprostaglandin dehydrogenase in the 100.000 g supernatant fraction of homogenized hamster lungs. Thus the decreased metabolism of PGE in the pulmonary circulation of hamster lungs is obviously not due to the inhibition of 15-hydroxyprostaglandin dehydrogenase. A more likely explanation seems to be the decreased uptake of PGE2 into the lung cells.</div>","PeriodicalId":76381,"journal":{"name":"Prostaglandins and medicine","volume":"6 4","pages":"Pages 441-447"},"PeriodicalIF":0.0,"publicationDate":"1981-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0161-4630(81)90077-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18292347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Monthly bibliography on prostaglandins prepared by the University of Sheffield Biomedical Information Service 谢菲尔德大学生物医学信息服务处编写的前列腺素月度参考书目

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90080-X

引用次数: 0

Some pharmacological effects of 17(S) methyl-ω-honiytrans-Δ2-PGE1 (ONO 1206) 17(S) methyl-ω-honiytrans-Δ2-PGE1 (ONO 1206)的药理作用

Prostaglandins and medicine Pub Date : 1981-04-01 DOI: 10.1016/0161-4630(81)90078-1

P.G. Adaikan, S.M.M. Karim

引用次数: 8