发布求助
文献互助 智能选刊 最新文献

Pathologia Europaea最新文献

筛选
英文 中文
Pituitary thyrotropic tumour secondary to long-standing primary hypothyroidism. 继发于长期原发性甲状腺功能减退的垂体促甲状腺瘤。
Pathologia Europaea Pub Date : 1976-01-01
A S Leong, J C Chawla, E C Teh
{"title":"Pituitary thyrotropic tumour secondary to long-standing primary hypothyroidism.","authors":"A S Leong,&nbsp;J C Chawla,&nbsp;E C Teh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pituitary neoplasms in primary myxoedema are rare and previously reported cases have mostly been described as chromophobe adenomas. None of them were subjected to modern methods of study. A 26 year-old woman with untreated primary hypothyroidism developed a pituitary tumour which produced bitemporal hemianopsia. Histochemical and ultrastructural studies characterized the tumour cells as thyrotrops. The secretory granules present had a mean diameter of 110 mum and were membrane-bound and surrounded by clear halos. Many of the tumour cells were actively secreting. They had reduced numbers of granules, possessed expanded Golgi complexes, abundant rough endoplasmic reticulum and free ribosomes. Cytoplasmic microfilaments were also seen. A possible mechanism of production of this tumour is discussed.</p>","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"11 1","pages":"49-55"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12117129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern ideas on chromosome structure. 染色体结构的现代观念。
Pathologia Europaea Pub Date : 1976-01-01
H G Schwarzacher
{"title":"Modern ideas on chromosome structure.","authors":"H G Schwarzacher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The structural element of an eukaryotic chromosome is the so-called chromatin fibre. It is a DNA-protein complex of about 100-200 A thickness and most probably running through from one end of a chromatid to the other. The fine structure of this DNA-protein fibre suggests a core of globular histone subunits around which the DNA-molecule is wound. The single strandedness of chromatids is suggested by the structure of premature condensed chromosomes. The course G-banding seen in metaphase chromosomes is presumably caused by groups of much finer bands seen in decondensed chromosomes. The number of such fine bands in the human genome is estimated to be 10 000-100 000, figures which are in the range of the number of genes in man.</p>","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"11 1","pages":"5-13"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12117130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrastructural aspects of the thyroid in a case of human congenital goitre with cretinism. 先天性甲状腺肿伴克汀病1例甲状腺超微结构的观察。
Pathologia Europaea Pub Date : 1975-01-01
P Ketelbant-Balasse, D Glinoer, P Neve
{"title":"Ultrastructural aspects of the thyroid in a case of human congenital goitre with cretinism.","authors":"P Ketelbant-Balasse,&nbsp;D Glinoer,&nbsp;P Neve","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Transmission electron microscope and scanning electron microscope studies in a case of congenital goitre associated with cretinism revealed the existence of two cell types: the first with rounded endoplasmic cisternae and normal lysosomes; the second characterized by an abundance of lysosomes and/or lipofuscin granules. Intermediary aspects suggested that the second cell type was the progeny of the first type. As colloid droplets and apical pseudopods engulfing colloid were nearly absent, and as NBE127I was elevated in the plasma, it is suggested that iodoprotein secretion occurred by a process different from colloid phagocytosis as observed after acute TSH stimulation.</p>","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"10 2","pages":"155-65"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11388856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electron microscopic observations on chronic aggressive hepatitis: participation of hepatocytes in liver fibrosis. 慢性侵袭性肝炎的电镜观察:肝细胞参与肝纤维化。
Pathologia Europaea Pub Date : 1975-01-01
J Groniowski, M Walski
{"title":"Electron microscopic observations on chronic aggressive hepatitis: participation of hepatocytes in liver fibrosis.","authors":"J Groniowski,&nbsp;M Walski","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"10 1","pages":"37-50"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12356036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro activity of cotrimoxazole on the intracellular multiplication of Toxoplasma gondii. 复方新诺明对刚地弓形虫胞内增殖的体外活性研究。
Pathologia Europaea Pub Date : 1975-01-01
B T Nguyen, S Stadtsbaeder
{"title":"In vitro activity of cotrimoxazole on the intracellular multiplication of Toxoplasma gondii.","authors":"B T Nguyen,&nbsp;S Stadtsbaeder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cotrimoxazole, from 60 mug/ml, inhibited the replication of Toxoplasma gondii within Hela cells and mouse peritoneal macrophages. The percentage of inhibition reached practically 100% after 18 hours of treatment at 37 degrees C. More prolonged treatment resulted in an eradication of the organisms from the cell monolayers. In contrast, similar doses of spiramycin were quite ineffective against intracellular toxoplasma. The active doses of cotrimoxazole used were not harmful for cell cultures. Cotrimoxazole also destroyed clones (rosaces) of toxoplasma which were formed during the past 18 hours of intracellular replication in the absence of the drug. Trimethoprim was the only effective compound of cotrimoxazole on intracellular parasites; the adjunction of sulfamethoxazole produced a marked synergistic effect. The present findings confirm the great efficiency of cotrimoxazole in the treatment of experimental toxoplasmosis in mice performed previously in this laboratory.</p>","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"10 4","pages":"307-15"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12385457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of hypotensive drugs (Serpasil) on the histochemical reactions in the small intestine of white rats. 降压药Serpasil对大鼠小肠组织化学反应的影响。
Pathologia Europaea Pub Date : 1975-01-01
I Królikowska-Prasal, J S Tarach
{"title":"The effect of hypotensive drugs (Serpasil) on the histochemical reactions in the small intestine of white rats.","authors":"I Królikowska-Prasal,&nbsp;J S Tarach","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of Serpasil (Ciba) on histological activities of dehydrogenases and reductases as well as on PAS-positive substances in the small intestine of white rats has been studied. It has been demonstrated that a decrease in the succinic, lactic and glucose-6-phosphate dehydrogenase activities as well as in the NADH and NADPH tetrazole reductase activities occurs in the rat's small intestine epithelial cells after the administration of Serpasil. However, a considerable intensification in the reactions to PAS-positive substances in the mucous cells and an increase in the amount of these cells has been observed.</p>","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"10 2","pages":"167-72"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12364337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colchicine-induced lesions in the rat duodenum. 秋水仙碱致大鼠十二指肠损伤。
Pathologia Europaea Pub Date : 1975-01-01
D Dinsdale
{"title":"Colchicine-induced lesions in the rat duodenum.","authors":"D Dinsdale","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In rats subcutaneous injection of colchicine resulted in sub-cellular necrosis within the rapidly proliferating cells in the duodenal mucosa. Similar lesions resulted from the administration of cytosine arabinoside hydrochloride and the effects of both drugs were ameliorated by treatment with cycloheximide. It is suggested that these lesions are a form of shrinkage necrosis involved in the deletion of growing stem-cells which, in the absence of mitotic division, results in mucosal atrophy.</p>","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"10 2","pages":"95-104"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11388857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mesangial changes of the renal glomerulus in long-term diabetic rats. 长期糖尿病大鼠肾小球系膜的改变。
Pathologia Europaea Pub Date : 1975-01-01
A Anjo, E Couturier
{"title":"Mesangial changes of the renal glomerulus in long-term diabetic rats.","authors":"A Anjo,&nbsp;E Couturier","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"10 1","pages":"21-7"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11389172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of angiotensin II upon platelet adhesiveness and the thrombelastogram in patients with essential arterial hypertension. 血管紧张素II对原发性动脉高血压患者血小板粘附性及血栓造影的影响。
Pathologia Europaea Pub Date : 1975-01-01
G Uza, I Crîsnic
{"title":"Effect of angiotensin II upon platelet adhesiveness and the thrombelastogram in patients with essential arterial hypertension.","authors":"G Uza,&nbsp;I Crîsnic","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Platelet adhesiveness increases significantly after angiotensin II administration, in pressor and subpressor doses, only in the hypertensive patients with urinary infection. The k index on the thrombelastogram decreases significantly following angiotensin II infusion in pressor doses both in the hypertensive patients with urinary infection and in those without urinary infection. At the same time, angiotensin II infusion in pressor and subpressor doses determines a significant increase of epsilon index in both hypertensive patients with urinary infection and in those without urinary infection. These results pose the problem of thrombocyte sensitization by the urinary infection to the vasopressor substance. The increased tendency to thrombosis by angiotensin, in hypertensive patients with urinary infection, could constitute a mechanism of malignant transformation of arterial hypertension.</p>","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"10 4","pages":"327-32"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12385459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrastructural comparison of the cell coat in normal and chronic lymphocytic leukaemic blood lymphocytes by Concanavalin A labelling and cationic staining. 用魔豆蛋白A标记和阳离子染色法比较正常和慢性淋巴细胞白血病淋巴细胞胞壁的超微结构。
Pathologia Europaea Pub Date : 1975-01-01
F Calman
{"title":"Ultrastructural comparison of the cell coat in normal and chronic lymphocytic leukaemic blood lymphocytes by Concanavalin A labelling and cationic staining.","authors":"F Calman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The ultrastructure of the cell coat of normal and chronic lymphocytic leukaemic (CLL) blood lymphocytes has been compared by several cytochemical techniques. In CLL lymphocytes, there is no modification of Concanavalin A labelling, whereas a difference of stainability is observed with at least one of the three cationic dyes used: colloidal iron, colloidal thorium, or ruthenium red, signifying a modification of anionic reactive sites. This physico-chemical surface anomaly is discussed with regard to other biochemical and electrophoretic results given by other authors.</p>","PeriodicalId":76308,"journal":{"name":"Pathologia Europaea","volume":"10 3","pages":"203-14"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11274831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书