{"title":"[Differential diagnosis and therapy of hypoglycemia in childhood].","authors":"K Mohnike, I Starke, N Bannert, H R Heise","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Occurrence of hypoglycaemia is directly connected to fuel balance. Compared to free fatty acids, glucose is rapidly exhausted. Therefore, besides disturbances in available glucose (i.e. defects in gluconeogenesis or glycogenolysis) as well as their hormonal control, defects of beta-oxidation might be possible causes. According to recent investigations they occurred with similar frequency. A blood glucose level of 2.6 mmol/l (= 47 mg%) already represents a critical concentration of brain function. Based on pathophysiological concepts concentrations of glucose, free fatty acids, ketone bodies and insulin must be determined from a single plasma sample. Together with case history and clinical symptom findings, these parameters are useful to get a reliable tentative diagnosis. Therefore, descriptions like \"ketotic\" or \"idiopathic\" hypoglycaemia can be avoided and suitable treatment can be started. Suspected diagnosis must be confirmed by means of chromatographic, enzymatic, and if necessary histological investigations. Successful treatment depends mainly on early diagnosis. This is of importance in case of surgery in organic hyperinsulinism, but likewise for advisory help to families with infants suffering from beta-oxidation defects, to avoid prolonged fasting.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"192-201"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19395319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sinobronchial syndrome--a meaningful diagnosis?].","authors":"W Leupold, P Wunderlich","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The term sinobronchial syndrome is often used, but there is no generally accepted definition. Due to the functional and clinical unity of the whole respiratory tract infectious and allergic irritations lead to homogeneous reactions of the bronchi and the paranasal sinuses. On the other hand there are hints that a disease in one region can cause problems in the other or reinforce it. Probably bronchi and sinuses can also become infected simultaneously from the pharynx. In chronic cases sinusitis and bronchitis are often only symptoms masking an underlying disease that requires differentiated diagnostics and treatment, e.g. cystic fibrosis, primary ciliary dyskinesia, and immunological defects.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 4-5","pages":"129-33"},"PeriodicalIF":0.0,"publicationDate":"1993-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19348420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Treatment of ocular toxoplasmosis. Part 2: Therapeutic approaches].","authors":"H Mittelviefhaus","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Retinochorioditis is the most common complication of ocular toxoplasmosis and also the most dangerous one in respect of central visual acuity. New treatment concepts are increasingly replacing the therapy that had become established since the fifties and that had been based on pyrimethamine and sulphadiazine. The new concepts entail fewer complications and are better accepted by the patients. However, prospective randomised studies that are based on severe criteria could not prove for any of the employed treatment courses that it promotes healing of retinochorioditis or prevents relapses. However, if central visual acuity is endangered, drug therapy should nevertheless be initiated. In babies and in persons with immunodeficiency treatment must be in accordance with the overall pattern of symptoms.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 4-5","pages":"154-60"},"PeriodicalIF":0.0,"publicationDate":"1993-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19348424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A further case with Baller-Gerold syndrome (craniosynostosis--radial aplasia syndrome)--overview and new viewpoints on a rare syndrome].","authors":"H Reichenbach, D Hörmann, H Theile","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Baller-Gerold syndrome is a rare malformation syndrome with craniosynostosis. A radial defect is the main feature of this combination besides the premature craniosynostosis. The entity and the etiology of this inherited trait was often discussed in recent years. This syndrome is further characterised and presented as a distinct entity with the reported new case. Parents of such a child should be aware of the 25% recurrence risk in subsequent siblings because of an autosomal recessive mode of inheritance.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 4-5","pages":"161-7"},"PeriodicalIF":0.0,"publicationDate":"1993-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19346906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The physician as expert witness. Aspects of an ambivalent role exemplified by expert testimony for legal health insurance].","authors":"E Nüchtern","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article provides a broad survey of the difficulties confronting the physician in his role as a specialist in the Health Insurance Medical Service, assessing claims relating to the state medical insurance system. These problems can be divided into the three following categories. Firstly, problems on a personal level relating to the interaction of the different people involved, albeit within the given institutional framework. Secondly, problems involving matters of principle in reconciling diagnosis, the patient's subjective assessment of his condition and legal criteria. Thirdly, problems arising from the pressure created by socio-cultural developments which influence both the patient and the specialist physician in his assessment.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 4-5","pages":"174-80"},"PeriodicalIF":0.0,"publicationDate":"1993-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19346909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Developmental delay in beginning students with resultant partial learning disorders].","authors":"A Wohlfeil","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There is an incomplete degree of school maturity in approximately ten per cent of our school beginners because of developmental delays which may have genetic or psychosocial causes or may be caused by an infantile cerebral dysfunction. A consequence of these developmental delays are the partial disturbances of performance frequently resulting in failure at school. An early registration of the partial disturbances of performance is important for the prognosis of these children in order to prevent the development of secondary unbalanced behaviour. Moreover an after maturation of the damaged cerebral centres can be reached by early support.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 4-5","pages":"144-50"},"PeriodicalIF":0.0,"publicationDate":"1993-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18692626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H G Kläber, T Erler, G Weigt, H Papsdorf, A Gurski
{"title":"[Hirschsprung disease. Discussion of a disease picture also relevant to neonatology].","authors":"H G Kläber, T Erler, G Weigt, H Papsdorf, A Gurski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The clinical disease pattern of an \"acute abdomen\" is by no means rare in newborn and very young infants and always signals an emergency situation. Besides inflammatory causes, congenital anomalies are among the most prominent reasons responsible for this condition. The example of 3 own patients serves to illustrate the disease pattern of Hirschsprung's disease, which is discussed with special reference to neonatology.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 4-5","pages":"139-43"},"PeriodicalIF":0.0,"publicationDate":"1993-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19348422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Follow-up and prognosis of pyelonephritis in infancy].","authors":"J Misselwitz, U John, S Vogt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>128 infants between 1 and 18 months, 80 girls and 48 boys suffering from their first pyelonephritis (PN), were investigated and followed up over 2.9 +/- 2.2 years (mean +/- SD). 20 children showed urinary tract obstructions. In 49 of 108 cases (45%) with nonobstructive PN a vesico-uretero-renal reflux (VUR) was found and surgically corrected in 13 cases. In 36 patients (52 renal units) the VUR disappeared in most cases under medical management within 3 years. Recurrences of urinary tract infections (UTI) were found in the same frequency in children with and without reflux (28%), but those with VUR showed significantly more PN. 22 of 108 patients with nonobstructive PN (20%) developed renal scars, 39% of children with reflux (mostly VUR III. or IV. degree), 5% of those without reflux. In more than half of these cases renal scars were found already after the first PN. We conclude that a reduction of the risk of renal damage and an improvement of the prognosis can achieved by the following measures: 1. early detection of obstruction by pre- or postnatal sonographic screening, 2. early and exact diagnosis of PN and antibiotic therapy without delay. PN has to be excluded in all infants with unclear fever. 3. In all infants with PN a voiding cystography should be performed. In children with VUR, long-term chemoprophylaxis is necessary to avoid recurrence of PN.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 4-5","pages":"134-8"},"PeriodicalIF":0.0,"publicationDate":"1993-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19348421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}