{"title":"[Compliance of children with bronchial asthma in long-term therapy with theophylline retard preparations].","authors":"E Köhler, V Sollich, R Schuster","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>427 samples of the saliva of 235 children were taken on an outpatient basis to follow up long-term theophylline treatment. 37 samples from 34 children did not reveal the presence of any theophylline. The absolute non-compliance found in this manner is 21% in the 9 to 12 years age bracket and significantly higher than with the children below 9 years and above 14 years of age (8 and 10%, respectively). Better differentiation of compliance and separation from underdosing was achieved in 38 children by comparing the outpatient-controlled theophylline levels with the values obtained on an inpatient basis. For 10 patients this method definitely revealed non-compliance, whereas compliance was doubtful with 12 children and 15 children had strictly adhered to the prescribed dosage regimen. To improve the intake discipline the theophylline levels should be regularly followed up under outpatient conditions and evaluated in cooperation with the patients.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"207-10"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19397118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hemophilus influenzae infection and their prevention by vaccination].","authors":"H Scholz, R Noack","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Encapsulated and non-encapsulated strains of haemophilus influenzae are known to exist. The encapsulated ones, especially those of type B (HiB), are highly invasive. Hib may cause, among other diseases, purulent meningitis, epiglottitis, septic arthritis/osteomyelitis and pneumonia. These diseases can be prevented by timely vaccination. The non-encapsulated haemophilus ionfluenzae strains often produce colonisation of the nasopharyngeal space and inflammation of the mucosa of the airways. They are often pathogens of otitis media, sinusitis, bronchitis and pneumonia. These diseases cannot be prevented by HiB vaccination.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"189-91"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19395318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Gosch, S Bretschneider, C Korb, W Lamme, H Schultz
{"title":"[Perinatal herpes infection. Clinical aspects--therapy--follow-up].","authors":"G Gosch, S Bretschneider, C Korb, W Lamme, H Schultz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Herpes simplex virus may cause serious infections in neonates. In case of foetal infection in the first trimenon, abortions, stillbirth, prematurity, intrauterine growth retardation (not obligatory) and various malformations may result. Neonatal HSV infection is mostly the consequence of intrapartum virus acquisition during passage through the birth canal. The infection is mostly localised on the skin, at the eyes or the mouth or disseminated with or without HSV meningoencephalitis. It is difficult to establish the diagnosis, because neonatal herpes disease in the early stage is not easy to distinguish from other diseases in the newborn such as RDS, NEC or ICH. Antiviral therapy with aciclovir is the treatment of choice and seems to improve the outcome of neonatal herpes. Prognosis depends on early therapy. Treatment should be initiated in relation to clinical findings, because available diagnostic techniques do not always permit an early detection of the disease.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"202-6"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19397117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Therapy of idiopathic thrombocytopenic purpura in childhood].","authors":"V Aumann, U Mittler, U Kluba, R Röppnack","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Idiopathic thrombocytopenic purpura characterised by an increased bleeding tendency is a well-known clinical entity in childhood. From 1983 to 1992 68 patients suffering from ITP were treated at the Children's Hospital of the Medical Academy of Magdeburg. 11 patients with mild or without clinical symptoms and platelet counts of more than 20 Gpt/l did not receive any treatment; all children recovered spontaneously. 38 patients with severe haemorrhagic manifestations and thrombocytes less than 20 Gpt/l were treated with corticosteroids and had a sustained remission. 10 patients who had responded to corticosteroids initially and subsequently relapsed were given other treatments (Anti-Rhesus-antibodies, HDIVG). All patients achieved a continuous remission. A chronic disease was observed in 8 patients; 3 of them were splenectomised. One child died due to massive gastrointestinal bleeding.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"223-6"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19397122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Exanthema with high fever and cerebral seizure susceptibility after mumps-measles-rubella (MMR) preventive vaccination?].","authors":"S Wiersbitzky, R Bruns, R Mentel","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"227-8"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19098380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Extremely marked local reaction (erythema, swelling, pain) after the 1st and 2nd DPT vaccination?].","authors":"S Wiersbitzky, R Bruns, U Schmidt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"235-6"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19397124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V Sollich, E Klöditz, R Schuster, W Handrick, S Brömme, W Rumler, R Patsch, H Kharari, F B Spencker
{"title":"[Oral ciprofloxacin therapy in juvenile patients with cystic fibrosis--results of a prospective pilot study].","authors":"V Sollich, E Klöditz, R Schuster, W Handrick, S Brömme, W Rumler, R Patsch, H Kharari, F B Spencker","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Efficacy and safety of oral ciprofloxacin were studied in a prospective study at three cystic fibrosis centres, covering 24 in-patients suffering from cystic fibrosis and acute bronchopulmonary exacerbation. The patients were between 10 and 17 years of age. Pseudomonas infection was present in 75% of these patients. Despite frequent persistence of the pathogens, clinical improvement was noted in 75% of the treated children. A definite increase of the average MIC was not seen in 20 cases of persisting strains. No serious side effects occurred during the 14-day oral treatment course. Ciprofloxacin is a useful alternative to conventional parenteral treatment with antibiotics in patients suffering from cystic fibrosis and infections of the airways.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"211-4"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19397119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Schultz, S Bretschneider, W Lamme, R Minda, E Canzler
{"title":"[Intrauterine stab injury with a knife in the head of a fetus in the 29th week of pregnancy].","authors":"H Schultz, S Bretschneider, W Lamme, R Minda, E Canzler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Penetrating head trauma in children causes uncommon and potentially life-threatening injuries. We report on a case of penetrating cranial stab wound to the right parietal region of the head to a 29-week fetus. The child was delivered by emergency Caesarian section. Neurosurgical intervention after birth was necessary. The injury caused a posthaemorrhagic hydrocephalus. Real-time ultrasound examination visualises the brain damage and the development of a hydrocephalus e vacuo.</p>","PeriodicalId":76073,"journal":{"name":"Kinderarztliche Praxis","volume":"61 6","pages":"215-8"},"PeriodicalIF":0.0,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19397120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}