{"title":"Acinic cell carcinomas of salivary glands histoprognosis. Value of NORs stained with AgNOR technique and examined with semi-automatic image analysis.","authors":"G Chomette, M Auriol, A Wann, F Guilbert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty one patients surgically treated for acinar cell salivary gland carcinomas were studied retrospectively. Four cases were excluded from the results because of an inadequate follow-up time (less than 5 years). The rest was classified into two groups: eleven patients with a favorable outcome were still alive without any recurrence after a mean follow-up period greater than 10 years; in six other patients, recurrences and metastases occurred followed by death in four cases. Previously for such tumors a high degree of histological undifferentiation usually gave rise to a poor prognosis, although some exceptions were noted. Thus, in an attempt to find a more reliable prognosis criterion, we evaluated by semi-quantitative image analysis nucleolar organizer regions by means of AgNOR count and mean area in all these cases. Our results significantly correlated with the clinical prognosis: a high count (more than 3) and a small mean area were always found in tumors with an unfavorable outcome whereas lower counts and larger mean areas were found in tumors with a favourable clinical course. Thus, this method showed promise as establishing the prognosis of acinar cell tumours.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 3","pages":"205-10"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12882577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of topical vitamin C on palatal oral mucosal carcinogenesis using 4-nitroquinoline-1-oxide.","authors":"S V Kandarkar, P C Reade","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Vitamin C is an essential nutrient whose protective influence in carcinogenesis has been reported frequently. In general, evidence suggests that vitamin C inhibits the formation of some carcinogens and decreases the incidence and delays the onset of neoplastic lesions but the mechanisms by which this occurs are not known. In 1973, Wallenius and Lekholm induced intra-oral palatal squamous cell carcinomas by the use of the water soluble carcinogen 4-nitroquinoline-1-oxide (4NQO) applied thrice weekly to the palatal mucosa of rats. The aim of this study was to determine if in rats topically applied vitamin C had an effect on the process of carcinogenesis caused by the application of 4NQO. The results of this study showed that in the 4NQO treated animals a progression through mild, moderate and severe dysplasia occurred prior to neoplastic changes at 24 weeks and that this progression was delayed in the animals treated topically with vitamin C. It can be concluded that topically applied vitamin C has a modulating effect on the neoplastic process induced by 4NQO in the palatal mucosa of rats.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 3","pages":"199-204"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13097972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Survival of Prevotella intermedia (Bacteroides intermedius) in transport media.","authors":"E Deveaux, P Delplanque, C Neut, C Romond","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Five transport media were selected for testing, in vitro, the survival of a pure strain of Prevotella intermedia (Bacteroides intermedius) for 6, 24, and 72 hours. Two were non-nutrient transport media (RTF and VMG IV). The three others (TG, PY, PYG) were nutrient media. An increase in the transport time, and manipulations in an aerobic atmosphere compromised the survival of the bacteria. PY ensured good survival of the bacteria. RTF seems to be the best medium for the transport of P. intermedia, when quantitative analysis is required.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 3","pages":"241-6"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13097977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The healing of cranial defects by demineralized osseous implants: a radiographic, histological and radioisotope-uptake study in rats.","authors":"A C De Bie, H Thierens, L R Dermaut, L De Ridder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this study was to evaluate by different techniques the healing effect of demineralized allogeneic bone in parietal cranial defects in rats. 45Ca incorporation was measured for nine consecutive weeks in groups of control and implanted rats. Repeated 99mTc MDP uptake measurements were performed for nine weeks on the same group of rats. Each measurement was preceded by a cranial radiography. At the end of the study the animals were sacrificed for histologic evaluation. The results of the 45Ca incorporation, 99mTc MDP uptake measurements and the histologic pictures confirmed the osteogenic capacity of demineralized allogenic bone. From the results it can concluded that 99mTc MDP uptake measurements are a powerful tool in the evaluation of the healing process. It can be utilized sequentially in the same animal and gives detailed information about the progress of osteogenic activity over the entire implant area.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 3","pages":"211-20"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13097973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of sodium lauryl sulfate on the uptake of fluoride from NaF and MFP by etched enamel in vitro.","authors":"P Barkvoll","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Melsen and Rolla (1983) have previously shown that sodium lauryl sulfate may reduce the cariostatic effect of fluoride when present together with sodium monofluorophosphate during topical application. The aim of the present study was to examine the in vitro deposition of fluoride on etched enamel during topical application with sodium fluoride in combination with sodium lauryl sulfate. In addition, uptake by etched enamel of fluoride sodium monofluorophosphate in combination with sodium lauryl sulfate was examined. It was found that sodium lauryl sulfate decreased the amount of fluoride taken up by the enamel.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 3","pages":"235-9"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13097976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intratubular crystal deposition and remineralization of carious dentin.","authors":"T Fusayama","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An analysis of accumulated experimental results, the mechanism of intratubular crystal deposition in the transparent layer and remineralization of the matrix of carious dentin has led to a more rounded concept and understanding of dentin caries relevant to clinical practice. The transparent layer of carious dentin is not sclerotic but is part of the demineralized softened dentin. The crystal precipitation in the tubules is an intermediate product in a slow demineralization process. Physiological remineralization occurs in matrix of the inner carious dentin which has crossbanded collagen fibers and odontoblastic processes. The overall process of dentin caries is re-examined and described in view of these concepts.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 3","pages":"255-62"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13097979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytokeratin profiles in oral epithelial: a review and a new classification.","authors":"M H Sawaf, J P Ouhayoun, N Forest","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article proposes a classification of oral epithelial and summarizes recent literature of cytokeratin expression in the oral cavity. The oral epithelial are subdivided into two major groups: superficial and deep epithelia. Epithelial lining the oral cavity, i.e., superficial, are essentially stratified squamous epithelia, with the exception of taste buds. The epithelium covering the dorsal tongue is a combination of keratinized and non-keratinized epithelia. Deep epithelia are of two kinds, odontogenic and glandular epithelia. This study provides a classification of the cytokeratins expressed in the oral cavity in healthy and pathological situations based on published data and our own studies. The profiles of these polypeptides in different oral epithelia should provide information that may be used in various disciplines of oral medicine.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 3","pages":"187-98"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12882576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Mourtada, F Blachier, P O Plasman, A Sener, W J Malaisse
{"title":"Stimulation of 45Ca uptake and amylase release by cationic amino acids in parotid cells.","authors":"A Mourtada, F Blachier, P O Plasman, A Sener, W J Malaisse","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>L-arginine, L-ornithine, L-lysine and L-histidine (each 10 mM) stimulated amylase release from rat parotid cells. The secretory response to the cationic amino acids was suppressed in the absence of extracellular Ca2+ and, at physiological Ca2+ concentration, coincided with stimulation of 45Ca net uptake by the parotid cells. All cationic amino acids also accumulated inside the parotid cells. Nevertheless, the concept that the stimulation of amylase release is merely attributable to depolarization of the plasma membrane, secondary to the accumulation of these positively charged amino acids in the parotid cells, is questioned in view of both the inverse correlation found between their secretory effects and degree of ionization and the knowledge that parotid cells are electrically inexcitable.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 2","pages":"119-24"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12882575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The effect of an experimental occlusal interference on the masticatory cycle recorded by electromagnetic pantography].","authors":"J N Godefroy, M Yardin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of occlusal interference on masticatory cycles have been studied in twenty nine volunteers with complete natural dentition, using an electromagnetic pantograph (Sirognatograph, Siemens A.G.). After a one week recall, a decrease in speed motion was noted and the range of cycles in the horizontal plane had been altered.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 2","pages":"141-6"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12996218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The transmission of Actinobacillus actinomycetemcomitans between spouses].","authors":"M Sixou, D Duffaut-Lagarrigue, J P Lodter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this investigation was to study the transmission of Actinobacillus actinomycetemcomitans (A.a) between husband and wife when one of them was affected by acute juvenile periodontitis (P.A.J.). The hypothesis tested was the role played by the reservoir of the non-infected partner in explaining the frequent recurrences of the disease in the affected spouse despite combined antibiotherapeutical and surgical treatments. Twenty subjects with P.A.J. were studied. A.a. was found in the sub-gingival flora of nineteen of them. This micro-organism was also isolated in each of the partners of the nineteen patients. Each couple presented strains of the same biotype. The serotypes were studied in seven of these couples and confirmed the results of the biotypes. All theses results are in favour of the transmission of A.a. between partners.</p>","PeriodicalId":75983,"journal":{"name":"Journal de biologie buccale","volume":"19 2","pages":"161-6"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13098676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}