{"title":"[Neuromuscular manifestation of sarcoidosis (author's transl)].","authors":"H J Schädlich, M Berger, A Stammler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Three of our own observations of neuromuscular manifestation of sarcoidosis are presented. In two cases, a slowly progredient myopathic syndrome was evident. This syndrome developed in mid-life and showed asymmetrical distribution. In another case, a polyneuropathic syndrome was seen, which mainly affected motor function of the lower extremities. None of these patients had typical findings on chest x-rays. Histological proof of granulomatous alterations of skeletal muscle was the first indication of sarcoidosis. With reference to a further observation, the diagnostical value of muscle biopsy in sarcoidosis without neuromuscular manifestation is discussed.</p>","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 8","pages":"399-406"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11472678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Neurological complications associated with paraproteinaemic hemoblastoses (author's transl)].","authors":"H Prange, U Kaboth, F W Spaar, B Gremse","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 8","pages":"387-98"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11440625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Problems of functional lateralization in psychiatric research (author's transl)].","authors":"G Ulrich","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 8","pages":"418-30"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11472450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Immunoreactions of the delayed type in patients with multiple sclerosis (author's transl)].","authors":"E Maida, M Micksche, K Summer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Skin tests were performed in 34 multiple sclerosis patients. The incidence of positive reactions was reduced in these patients compared with healthy controls, with regard to different recall antigens with the exception of varidase, as well as the PHA and DNCB. No definite differences in reaction between patients who had been suffering from multiple sclerosis for a long time or for a short time, could be established. However, there was a certain dependence on the stage of the disease in so far as positive reactions were less frequent during the acute episode--more pronounced during the subsiding attack than at the onset of the episode--, than during the interval between two attacks. These results suggest that multiple sclerosis is primarily characterised by a weakness of cell-mediated immunity and that this weakness becomes more pronounced during the acute episode. The differences between the skin test reactions performed during the individual phases of the disease are too slight to assist in defining the acute episodes. It may be possible to identify changes in the reaction level via long-term studies.</p>","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 8","pages":"431-5"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11528487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[On relapsing paraneoplastic cerebral embolism. Case report and survey of literature (author's transl)].","authors":"A Zieger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The disease of a 34-year-old patient with relapsing cerebral embolisms, endocarditis, thrombophlebitis and hypercoagulopathy had the characteristics of paraneoplastic syndromes described and discussed in literature. Autopsy yielded a clinically unrecognised, dedifferentiated adenocarcinoma of the bronchial system. At an early stage of the disease cerebral embolisms had produced severe cerebral neurological signs with varying manifestations. This influenced not only the clinical picture and course of the disease to a considerable extent, but also focussed diagnostic attention on these signs to such a degree that the possibility of a masked carcinoma did not seem to suggest itself. The assumption of paraneoplastic linkups is supported by experimental and postmortem examinations on metabolic and immunological remote action of tumours on cardiac valves and on the vascular and coagulation system. However, the exact pathogenetic details are still largely unknown.</p>","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 7","pages":"377-83"},"PeriodicalIF":0.0,"publicationDate":"1979-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11473082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Quantitative measurement of muscle tone in patients with Parkinsonism before and during therapy with madopar (author's transl)].","authors":"J J Eisenlohr, W Gehlen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Muscle tone at rest and during passive movement was measured in 13 patients with Parkinsonism before and during Madopar therapy. We used the method of kommutative therapy with additional therapy. Data were obtained by myointegration using surface electrodes on the musc. biceps brachii. As already communicated earlier for measurements during passive movements, we could now also state a significant decrease of rigidity at rest during therapy with Madopar. The rigidity improved by 77,5% after an average duration of treatment of 6,25 months and by 84,8% after 25,7 months. There was a proportional dependence between the degree of rigidity at rest and rigidity during passive movements before therapy. Beyond that the decrease for both types of rigidity was approximately similar during therapy. Furthermore possible pathophysiological sources and correlations of alterations of muscle tone in man are discussed.</p>","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 7","pages":"331-46"},"PeriodicalIF":0.0,"publicationDate":"1979-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11473079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Psychic impairment and echoencephalographic findings in patients with cerebral contusions (author's transl)].","authors":"S Weinmann","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 7","pages":"347-76"},"PeriodicalIF":0.0,"publicationDate":"1979-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11473080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The carpal tunnel syndrome--clinical symptomatology and electrophysiological findings (author's transl)].","authors":"C Aebi-Ochsner, H P Ludin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the first part of this study 17 patients with a clinically clear-cut carpal tunnel syndrome but with normal electrophysiological findings have been controlled after 1 to 3 years. In 12 of these patients an other cause of the complaints could be found. In 2 patients no definite diagnosis could be made and in 3 the previous diagnosis was considered to be corrected. Control electromyography was pathological in 2 of them and 1 patient was symptom-free after the operation. In the second part 133 hands with clinical symptoms of a carpal tunnel syndrome were examined clinically and electrophysiologically. In the group of patients with pathological electrophysiological findings there were significantly more objective signs than in those with normal EMG findings. In 13 of these patients which could be followed an other diagnosis could be made. It was not possible to establish a clinical index for the carpal tunnel syndorme. For a definite diagnosis, positive clinical and electrophysiological findings are required.</p>","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 6","pages":"307-19"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11473077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Objectivation of tremor and motion disorders via computerisation (author's transl)].","authors":"W Birg, M Klar, W U Weitbrecht, F Mundinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The quantitative analysis of motion disorders of the upper extremities can be performed by means of a joystick connected with a minicomputer. Therefore a random squarewave curve is drawn on a computer display and the patient must follow it with the joystick. The deviation of the two curves are recorded, analysed and documented numerically and graphically.</p>","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 6","pages":"326-3"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11589119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[On the temperature sensitivity of multiple sclerosis patients (author's transl)].","authors":"M Brenneis, G Harrer, H Selzer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Aggravation of neurological symptoms in MS patients in heating is well known. This phenomenon is explained by the change of conduction in demyelinated nerve fibers. In raised temperature conduction block occurs. The threshold of conduction block dependent on temperature, is probably proportional to the degree of demyelination. It is possible to inhibit this effect by tyrosin. This model may present a view to a part of neurophysiological mechanisms of MS, on which we possibly can take therapeutical influence. By way of a questionnaire 125 MS patients were asked about changes of their symptoms in heating or cooling. 93% had marked sensitivity to heating. In 90% worsening of neurological symptoms or of general feeling occured in a hot bath. On the other hand about half the patients reported improvement in a cold bath. Therefore we suggest, that a noticeable part of neurological deficit is reversible, if we were able to raise the threshold of conduction block, which depends on temperature, ph, electrolytes and neurotransmitters.</p>","PeriodicalId":75864,"journal":{"name":"Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete","volume":"47 6","pages":"320-5"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11473078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}