American journal of perinatology最新文献

{"title":"Hospital Costs of Severe Maternal Morbidity Hospitalizations in the United States from 2014 to 2019: A Nationwide Cross-Sectional Study.","authors":"Mohammad A Salameh, Megan E Branda, Bijan J Borah, Vanessa E Torbenson","doi":"10.1055/a-2618-7331","DOIUrl":"10.1055/a-2618-7331","url":null,"abstract":"<p><p>The objective of this study was to estimate the average hospitalization cost (AHC) for deliveries affected by severe maternal morbidity (SMM) and analyze trends from 2014 to 2019. The study also aimed to explore cost stratification based on patient, delivery, and hospital characteristics.Using the National Inpatient Sample dataset, all delivery hospitalizations from 2014 to 2019 were identified. Deliveries affected by SMM were determined based on the Centers for Disease Control definition. Deliveries were categorized into three groups: no SMM (nSMM), any SMM (aSMM), and SMM excluding cases with blood transfusion as the only indicator (SMMeBTo). A regression model accounting for survey design and adjusting for variables including age, race/ethnicity, primary payer, income, delivery method, hospital location/teaching status, and hospital region was used to test the trends in incidence. Hospital charges were adjusted using cost-to-charge ratios and presented in 2022 U.S. dollars ($). A regression model adjusting for the same variables was used to assess costs.From 2014 to 2019, 4,444,957 deliveries were identified, with a weighted estimate of 22,224,775. The rates of aSMM and SMMeBTo were 1.9 and 0.7%, respectively. AHC was $5,218 (95% confidence intervals [CI]: $5,200-5,235) for nSMM, $11,101 (95% CI: $11,038-11,165) for aSMM, and $11,541 (95% CI: $114,330-11,650) for SMMeBTo. Hospitalization costs across all SMM categories rose annually from 2014 to 2017, decreased in 2018, and peaked in 2019. All races had significantly higher costs than non-Hispanic Whites across all SMM categories. SMM costs were higher for cesarean deliveries. The highest cost was in deliveries involving a temporary tracheostomy. Urban teaching hospitals and those in the Northeast had the highest SMM costs.Deliveries affected by SMM incur significantly higher costs, with these costs increasing over time. Understanding disparities across patient factors, delivery methods, and hospital characteristics can inform interventions aimed at addressing inequities. · Costs of SMM hospitalizations are rising, even after adjusting for inflation.. · The escalating cost burden is disproportionately shouldered by different racial groups.. · Factors in delivery and hospital settings contribute to the variation in cost..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Generative AI to Enhance Obstetrics and Gynecology Research.","authors":"Tetsuya Kawakita, Melissa S Wong, Kelly S Gibson, Megha Gupta, Alexis C Gimovsky, Hind N Moussa, Heo J Hye","doi":"10.1055/a-2616-4182","DOIUrl":"10.1055/a-2616-4182","url":null,"abstract":"&lt;p&gt;&lt;p&gt;The rapid evolution of large-language models such as ChatGPT, Claude, and Gemini is reshaping the methodological landscape of obstetrics and gynecology (OBGYN) research. This narrative review provides a comprehensive account of generative AI capabilities, key use cases, and recommended safeguards for investigators. First, generative AI expedites hypothesis generation, enabling researchers to interrogate vast corpora and surface plausible, overlooked questions. Second, it streamlines systematic reviews by composing optimized search strings, screening titles and abstracts, and identifying full-text discrepancies. Third, AI assistants can draft reproducible analytic code, perform preliminary descriptive or inferential analyses, and create publication-ready tables and figures. Fourth, the models support scholarly writing by suggesting journal-specific headings, refining prose, harmonizing references, and translating technical content for multidisciplinary audiences. Fifth, they augment peer-review and editorial workflows by delivering evidence-focused critiques. In educational settings, these models can create adaptive curricula and interactive simulations for trainees, fostering digital literacy and evidence-based practice early in professional development among clinicians. Integration into clinical decision-support pipelines is also foreseeable, warranting proactive governance. Notwithstanding these opportunities, responsible use demands vigilant oversight. Large-language models occasionally fabricate citations or misinterpret domain-specific data (\"hallucinations\"), potentially propagating misinformation. Outputs are highly prompt-dependent, creating a reliance on informed prompt engineering that may disadvantage less technical clinicians. Moreover, uploading protected health information or copyrighted text raises privacy, security, and intellectual property concerns. We outline best-practice recommendations: maintain human verification of all AI-generated content; cross-validate references with primary databases; employ privacy-preserving, on-premises deployments for sensitive data; document prompts for reproducibility; and disclose AI involvement transparently. In summary, generative AI offers a powerful adjunct for OBGYN scientists by accelerating topic formulation, evidence synthesis, data analysis, manuscript preparation, and peer review. When coupled with rigorous oversight and ethical safeguards, these tools can enhance productivity without compromising scientific integrity. Future studies should quantify accuracy, bias, and downstream patient impact. · Generative AI supports various research stages in OBGYN, such as hypothesis generation, systematic review assistance, data analysis, and scientific writing, demonstrating its potential to streamline research workflows and improve research efficiency.. · Generative AI has notable limitations, including the risk of generating inaccurate references (\"hallucinations\") and the need for care","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Practice of Kidney Support Therapy in the NICU: Results from a CHNC Survey.","authors":"Christine Stoops, Sofia I Perazzo, Jennifer A Rumpel, Tahagod Mohamed, Andrew M South, Mona Khattab, Catherine Joseph, Matthew W Harer, Cara L Slagle, Mary Revenis, John Daniel","doi":"10.1055/a-2608-0889","DOIUrl":"https://doi.org/10.1055/a-2608-0889","url":null,"abstract":"<p><p>In a survey conducted within the Children's Hospital Neonatal Consortium (CHNC), the Kidney Focus Group aimed to describe the resource and practice variations among participating level IV neonatal intensive care units.A 24-question survey was developed by neonatologists and pediatric nephrologists who belong to the Kidney Support Therapy (KST) subgroup of the CHNC Kidney Focus Group.The majority (89.5%) of responding centers offered some form of KST, with > 90% centers offered prenatal consultations. The most common KST modality offered were peritoneal dialysis (PD) and continuous renal replacement therapy (CRRT) while on ECMO. Prismaflex was the most common device used for stand-alone CRRT. The most common indication for KST initiation was fluid overload and body weight was indicated as the most common limiting factor with the majority of centers reporting weight limitation ≤ 1.5-2 kg.Advances in technology have made it possible to offer KST to a wider neonatal population than before. However, the availability of such technologies can vary significantly among institutions in addition to diversity of clinical experience and standardized protocols. This survey provides valuable insights into current KST practices across 19 level IV NICUs within the CHNC demonstrating expected practice variations amongst centers that may be dependent on location, center resources, and subspecialty providers, among others. · Considerable practice variation exists in KST among NICUs.. · Majority of NICUs utilize multi-disciplinary involvement, but subspecialties vary widely.. · The most common indication for KST initiation was fluid overload..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Hemorrhage Morbidity in Deliveries Complicated by Elevated Body Mass Index.","authors":"Hailie Ciomperlik, Rachel L Wiley, Ipsita Ghose, Anna Whelan, Hector Mendez-Figueroa, Suneet P Chauhan","doi":"10.1055/a-2600-7069","DOIUrl":"10.1055/a-2600-7069","url":null,"abstract":"<p><p>The relationship between body mass index (BMI) ≥ 30 in pregnancy and postpartum hemorrhage (PPH) has been unclear. While some risk stratification protocols classify elevated BMI as a moderate risk factor others do not. This study aimed to examine the effect of elevated BMI on PPH in a contemporary population.This retrospective cohort study included all singletons ≥14 weeks with recorded BMI who delivered at a Level IV center for two consecutive years. The exposure group was sub-categorized into BMI of 30 to 39.9 and BMI ≥ 40 kg/m², with a planned subgroup by mode of delivery. Data was collected by clinicians, and the composite maternal hemorrhagic outcome (CMHO) was defined as: blood loss ≥ 1,000 mL, interventions for atony including use of uterotonics (excluding prophylactic oxytocin), mechanical tamponade, surgical intervention, venous thromboembolism, admission to the intensive care unit, hysterectomy, or maternal death. Adjusted relative risks (aRR) with 95% confidence intervals (CI) were calculated using multivariate Poisson regression with robust error variance.Of 8,623 deliveries in the study period, 8,340 (96.7%) met inclusion criteria, with 2,943 (35%) with BMI < 30.0, 3,900 (46%) with BMI of 30 to 39.9 kg/m², and 1,497 (17%) with BMI of ≥40 kg/m². CHMO was increased for BMI of 30 to 39.9 (aRR: 1.16; 95% CI: 1.04-1.29) and ≥40.0 (aRR: 1.19; 95% CI: 1.04-1.36), largely due to increased risk of blood loss ≥ 1,000 and uterotonic use. A subgroup analysis by mode of delivery noted that increased risk for CHMO was only present in BMI ≥ 40 for vaginal deliveries (aRR: 1.35; 95% CI: 1.10-1.65) and only for BMI of 30 to 39.9 in cesarean delivery (aRR: 1.28; 95% CI: 1.10-1.50).Parturients with BMI ≥ 30 had a higher risk of hemorrhage-related morbidity compared with patients with BMI < 30, however, clinical management and impact need further investigation. · Patients with an elevated BMI had a higher risk of hemorrhage-related morbidity.. · Individuals with BMI ≥ 40 kg/m2 are at increased risk of hemorrhage with vaginal deliveries.. · With rising BMI rates, research on perinatal risks and targeted interventions is crucial for better..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Bundle to Reduce Infectious Morbidity after Cesarean Delivery in Individuals with Morbid Obesity.","authors":"Martina Benuzzi, Misa Hayasaka, Alyssa Savelli, George Saade, Emily Peters, Tetsuya Kawakita","doi":"10.1055/a-2620-7831","DOIUrl":"10.1055/a-2620-7831","url":null,"abstract":"<p><p>This study aimed to evaluate whether the implementation of a surgical bundle reduces surgical site infections (SSI), hospital readmission rates, and emergency department (ED) visits within 6 weeks in individuals with a body mass index (BMI) of 40 kg/m² or greater after cesarean delivery.This was a retrospective study including individuals with morbid obesity undergoing cesarean delivery at 23 weeks of gestation or greater. The preintervention period spanned from January 2017 to December 2020. The postintervention period extended from January 2021 to April 2023. The surgical bundle included standard preprocedure prophylactic antibiotics and a 48-hour course of oral cephalexin and metronidazole. The primary outcome was SSIs while secondary outcomes included hospital readmission or ED visits within 6 weeks postpartum or wound complications (dehiscence, seroma, or hematoma). Adjusted relative risks (aRR) with 95% confidence intervals (95% CI) were calculated using modified Poisson regression, adjusting for potential confounders.Of 2,105 pregnancies, 1,308 (62.1%) underwent cesarean in the preintervention period and 797 (37.9%) in the postintervention period. Compared to the preintervention period, the postintervention period had increased use of azithromycin (30.6 vs. 35.9%; <i>p</i> = 0.012), cephalexin (1.8 vs. 52.8%; <i>p</i> < 0.001), and metronidazole (3.1 vs. 60.4%; <i>p</i> < 0.001). However, compared to the preintervention period, the postintervention period had a similar risk of SSIs (6.6 vs. 5.9%; aRR: 0.92; 95% CI: 0.66-1.28), readmission or ED visits (19.8 vs. 19.8%; aRR: 0.94; 95% CI: 0.80-1.11), and wound complications (4.7 vs. 6.4%; aRR: 1.37; 95% CI: 0.96-1.96). In individuals with labor or ruptured membranes, the postintervention period had increased use of azithromycin (74.9 vs. 82.3%; <i>p</i> = 0.022), cephalexin (2.5 vs. 56.1%; <i>p</i> < 0.001), and metronidazole (4.3 vs. 63.8%; <i>p</i> < 0.001). In this subgroup, outcomes remained insignificant.A morbid obesity surgical bundle increased antibiotic use but did not reduce SSIs, hospital readmission, ED department visits, and wound complications. · A surgical bundle for individuals with morbid obesity increased the use of postoperative antibiotics.. · The surgical bundle did not significantly reduce SSIs.. · The surgical bundle did not significantly reduce hospital readmissions and ED visits..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Yoga in the NICU for parents (YIN): A pilot study on reducing stress in the Neonatal Intensive Care Unit.","authors":"Sara Neches, Alanna Feltner, Mihai Puia-Dumitrescu, Krystle Perez, Leanne Matullo, Dennis Mayock, Sandra E Juul","doi":"10.1055/a-2629-0956","DOIUrl":"https://doi.org/10.1055/a-2629-0956","url":null,"abstract":"<p><strong>Objective: </strong>To explore the effect of a 6-week online program of yogic breathing, meditation, and gentle postures for parents of infants hospitalized in the neonatal intensive care unit (NICU).</p><p><strong>Study design: </strong>From Oct 2021 to Oct 2023, we conducted a two-center pilot study of yoga for NICU parents. We assigned consented parents of NICU inpatients to receive yoga classes (YG) and/or usual care for parent support (UC) within 14 days of admission to the NICU. Self-directed yoga sessions were completed using an online platform. Usual care included parental support as practiced in each NICU and served as a control group. Primary outcomes were assessed at study entrance, midpoint and conclusion using the Parental Stressor Scale: Neonatal Intensive Care Unit (PSS: NICU) and the Postpartum Bonding Questionnaire (PBQ) in English and Spanish.</p><p><strong>Results: </strong>N=51 parents (71%) mothers were allocated using parallel assignment to UC (N=28, 55%) or YG (N=23, 45%). A total of N=39(76%) parents completed the classes to the midpoint of the study and N=33(65%) completed all 6-weeks of the study. There were no differences in baseline characteristics for parents or infants between groups. Average participation in the online yoga materials was 3hrs 45min per parent. A significant decrease in NICU related parent stress emerged for all PSS: NICU subscales and total PSS: NICU score for parents assigned to YG between enrollment and the midpoint of the study. Neither parents in UC nor YG approached thresholds indicating disorders of the parent-infant relationship as assessed by the postpartum bonding questionnaire.</p><p><strong>Conclusion: </strong>When initiated early, an online, asynchronous yoga intervention designed for parents may reduce NICU parent stress.</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Different Risk Assessment Models for Predicting Postdischarge Phototherapy Requirement in Term and Late Preterm Neonates.","authors":"Selma Aktas, Enes Dursun, Irem Yasa, Bala Ascıoglu","doi":"10.1055/a-2616-4116","DOIUrl":"10.1055/a-2616-4116","url":null,"abstract":"<p><p>This study was conducted to compare the Bhutani nomogram and the difference between the total serum bilirubin measurement at discharge and the AAP phototherapy threshold at the time of measurement (Δ-TSB) for predicting the postdischarge bilirubin level that will exceed the phototherapy threshold.Healthy neonates born at ≥35 weeks of gestation, followed in the newborn nursery, who did not receive phototherapy during hospital stay after birth, and who followed up in the outpatient clinic at least for 1 month from 2019 to 2024 were included in the study. Four logistic models were compared (D-TSB-plus,which encompassed additional variables such as gestational age, delivery type, and blood incompatibility, and DAT positivity, the Bhutani risk zones, and Bhutani-plus which encompassed additional variables such as gestational age, delivery type, and blood incompatibility) to predict postdischarge phototherapy requirement.Of the 2,040 neonates included in the study, 208 were readmitted for phototherapy treatment after discharge. ABO and/or Rh incompatibility, Bhutani risk zone, lower gestational age, and being born vaginally increased the need for phototherapy. Δ-TSB was the strongest predictor of postdischarge phototherapy requirement (<i>p</i> < 10^-50). Among the logistic models, the Δ-TSB-plus model had the highest predictive power (AUC: 0.83), followed by Δ-TSB alone (AUC: 0.82), Bhutani-plus (AUC: 0.80) and Bhutani alone (AUC: 0.74) models, respectively.Δ-TSB models had higher predictive ability regarding postdischarge phototherapy requirement compared with Bhutani models. Combining Bhutani risk zones with risk factors, especially with gestational age, increased the discrimination but did not reach the success of Δ-TSB models. · It is important to predict neonates likely to develop jaundice to start treatment in a timely manner.. · Combining bilirubin measurement with hemolysis findings and clinical parameters improves the prediction of postdischarge phototherapy.. · Δ-TSB model appears to be the strongest model for the prediction of postdischarge phototherapy requirement..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis and 10-years follow up of type-II generalized arterial calcification of the infancy.","authors":"Daniele De Luca, Daniela Laux, Giulia Regiroli, Alexandra Benachi, Alexandre J Vivanti","doi":"10.1055/a-2628-9607","DOIUrl":"https://doi.org/10.1055/a-2628-9607","url":null,"abstract":"<p><strong>Background: </strong>Generalized arterial calcification of infancy (GACI) is an ultra-rare, potentially life-threatening disorder of the mineralization of which obstetricians and neonatologists shall be aware.</p><p><strong>Objective: </strong>to describe twins with ATP binding cassette subfamily C member-6 (ABCC6) mutations leading to Type II-GACI phenotype in one of them, their multidisciplinary management and very long-term (10 years) follow up.</p><p><strong>Results: </strong>One of the twins had typical calcifications in the ascending aorta and the aortic arc, leading to severe neonatal arterial hypertension needing anti-hypertensive treatment. A therapy with bisphosphonates was also provided for three weeks with disappearance of calcifications and resolution of the hypertension. 10-year follow up was completely normal. Patients were found to carry a heterozygous mutation of ABCC6.</p><p><strong>Conclusion: </strong>Type II-GACI can be managed with multi-disciplinary approach and good long-term outcome despite the occurrence of severe neonatal arterial hypertension.</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal weight extrapolation following a third-trimester ultrasound examination using the gestation-adjusted projection method: a systematic review and meta-analysis.","authors":"Micah Martin Vaughn-Valencia, Yan D Zhao, Rodney K Edwards, Shari Clifton, Hugh Nadeau","doi":"10.1055/a-2628-2364","DOIUrl":"https://doi.org/10.1055/a-2628-2364","url":null,"abstract":"<p><p>Objective Using systematic review and meta-analysis methodology, we sought to evaluate the accuracy of the gestation-adjusted projection (GAP) method of fetal weight extrapolation in the prediction of actual birth weight. Study Design A systematic literature search was performed using MEDLINE/PubMed, Embase, Scopus, and Web of Science for studies published from database inception to June 2023. Studies were compiled that assessed accuracy of the GAP method in pregnant women at term (≥37 weeks' gestation) with an ultrasound performed at 34 to 36 weeks' gestation. Quality was assessed using the Newcastle-Ottawa Scale, and risk of bias was assessed using the Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I) tool. Meta-analysis was performed to evaluate the agreement between the GAP method and the actual birth weight using the mean percent error, mean absolute error, and mean absolute percent error. Means and 95% confidence intervals (95% CI) were calculated. Heterogeneity between studies was assessed using I² and tau² statistics. Results The search identified 949 records. After full text review, a total of eight studies with 5306 subjects were included. Studies were retrospective and prospective cohort studies. All studies were deemed high quality and determined to have a low risk of bias. Five studies were performed in the United States, one in Italy, one in Spain, and one in the United Kingdom. Four studies included patients with pregestational or gestational diabetes and obesity. Due to substantial heterogeneity, the random-effects model was used to estimate the effects of studies. The mean percent error was 3.1% (95% CI: 1.1-5.2%), the mean absolute error was 240 g (95% CI: 205-275 g), and the mean absolute percent error was 8.0% (95% CI: 6.9-9.1%). Conclusion The GAP method of fetal weight extrapolation is an accurate approach to birth weight prediction and is suitable for use in a diverse population.</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Head Ultrasound Findings in Infants with Birth Weight >1,500 g and Gestational Age >32 Weeks Exposed to Prenatal Opioids\".","authors":"Shubham Kumar, Rachana Mehta, Ranjana Sah","doi":"10.1055/a-2616-4091","DOIUrl":"10.1055/a-2616-4091","url":null,"abstract":"","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}