American Journal of Hypertension最新文献

{"title":"Hypertension Summer School Sponsored by American Journal of Hypertension, July 25-29, 2024, Loyola University, Chicago, Illinois.","authors":"Karen A Griffin, Fernanda B M Priviero, Cameron G McCarthy, Katherine T Mills, Carolina B Restini, Rinaldo Rodrigues Dos Passos, Raymond R Townsend, Mark J Uline, Emma Wabel, Stephanie W Watts, Jan M Williams, R Clinton Webb","doi":"10.1093/ajh/hpag106","DOIUrl":"https://doi.org/10.1093/ajh/hpag106","url":null,"abstract":"","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148928771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antihypertensive Pharmacotherapy in Chronic Kidney Disease: Integrating eGFR-Based Cutoffs, Mechanistic Insights, and Emerging Therapeutic Pathways.","authors":"Sriram Sriperumbuduri, Rachel W Khan, Soyeb Aftab, Swapnil Hiremath, Dave Dixon, Gaurav Gupta","doi":"10.1093/ajh/hpag111","DOIUrl":"https://doi.org/10.1093/ajh/hpag111","url":null,"abstract":"<p><p>Optimal hypertension management requires not only stringent blood pressure control but also concomitant management of related cardiovascular, metabolic, and kidney comorbidities. Emerging evidence demonstrates that contemporary therapies improve albuminuria, estimated glomerular filtration rate trajectory, kidney outcomes, and cardiovascular outcomes, although the relative contributions of sustained blood pressure reduction and other biologic effects cannot always be separated. This review examines the impact of current and emerging treatment strategies across three core domains: blood pressure control, kidney function trajectory, and albuminuria reduction. Emphasis is placed on kidney function-based treatment selection, safety considerations including advanced disease, the role of targeted therapy in dysregulated aldosterone states, and evolving options for resistant hypertension. A risk- and clinical-characteristic-guided approach that integrates kidney stage, degree of albuminuria, and overall cardiovascular risk is proposed to move beyond uniform drug escalation toward personalized care. Early risk stratification, thoughtful sequencing, and structured monitoring are essential to translate therapeutic advances into sustained kidney and cardiovascular benefit.</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of Program Adherence and Motivation with Blood Pressure Reduction in a Digital Therapeutic for Hypertension: The B-INDEX Study.","authors":"Naoko Tomitani, Tomoko Morimoto, Noriko Harada, Satoshi Hoshide, Kazuomi Kario","doi":"10.1093/ajh/hpag107","DOIUrl":"https://doi.org/10.1093/ajh/hpag107","url":null,"abstract":"<p><strong>Background: </strong>Although digital therapeutics (DTx) have shown efficacy for reducing the blood pressure (BP) of individuals with hypertension, the relative contributions of program adherence (objective) and patient motivation (subjective) to the antihypertensive effects of DTx remain unclear.</p><p><strong>Methods: </strong>We analyzed data from the B-INDEX (Behavioral Modification Index) study, evaluating the BP-lowering effects by DTx. Program adherence was quantified using app-based usage metrics. Questionnaires assessed the DTx users' motivation. Associations between these factors and systolic BP (SBP) reduction were examined.</p><p><strong>Results: </strong>Among 198 patients with hypertension (mean age 54.9 ± 10.6 years, 57.1% male, mean body mass index 26.7 ± 5.3 kg/m2, 57.6% taking antihypertensives), higher program adherence was associated with greater reductions in SBP at Week 24 (-8.0 vs -2.5 mmHg, p < 0.001), whereas higher motivation scores showed no significant association with SBP reduction (-7.3 vs -5.6 mmHg, p = 0.257). In contrast, body weight reduction and improvements in salt-intake scores showed similar patterns across adherence- and motivation-based subgroup analyses.</p><p><strong>Conclusions: </strong>Motivation is important for lifestyle modification, but objective program adherence was more strongly associated with SBP reduction than subjective motivation. Objective behavioral indices may better reflect lifestyle changes relevant to the antihypertensive effects of DTx.</p><p><strong>Clinical trial registration: </strong>UMIN000050479 (https://www.umin.ac.jp/ctr/).</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of Clinical Hypertension Guidelines and Single Pill Combinations: A Qualitative Study in Australian General Practice.","authors":"Sonali R Gnanenthiran, Isabella Tan, Miriam Pikkemaat, Mingjuan Zeng, Charlotte Hespe, Markus P Schlaich, Anthony Rodgers, Aletta E Schutte","doi":"10.1093/ajh/hpag109","DOIUrl":"https://doi.org/10.1093/ajh/hpag109","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is the leading cause of preventable deaths worldwide, yet blood pressure (BP) control remains poor in Australia when compared to other similar higher income countries. This study aims to explore general practitioners' (GPs) perceptions of hypertension management and single pill combination (SPC) to identify barriers and facilitators to guideline implementation and SPC use in Australia.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 20 GPs (June-July 2024). Participants were purposively sampled to ensure diversity (age, sex, experience, location). Interviews explored diagnosis, treatment, monitoring, and attitudes toward guidelines and single pill combinations (SPCs). Transcripts were analyzed using a combined deductive-inductive approach guided by the Consolidated Framework for Implementation Research.</p><p><strong>Results: </strong>GPs demonstrated limited awareness of recent international guideline updates and relied predominantly on the 2016 Australian guidelines, with most initiating treatment with monotherapy and targeting BP < 140/90 mmHg. SPCs were rarely used early and were perceived as difficult to titrate. Practice-level audits of BP control were absent, team-based care was inconsistently implemented. Therapeutic inertia and non-adherence to antihypertensive therapy-key barriers to BP control-were rarely acknowledged. Younger and academically affiliated GPs were more receptive to SPCs and lower BP targets, while experienced GPs often favored conservative, stepwise escalation partly due to concerns of side-effects.</p><p><strong>Conclusions: </strong>Whilst hypertension management in Australian general practice overall aligns with current national guidelines, an update to the 2016 guidelines is urgently needed to reflect best-evidence, particularly on the use of SPCs and strengthening of team-based care to improve BP control.</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"24-hour Blood Pressure Variability and Falls Among Older Adults with Hypertension Taking Antihypertensive Medication: Results from the AMBROSIA Study.","authors":"Keisuke Narita, Rong Wei, Teresa N Harrison, Kimberly Cannavale, Lei Qian, C Barrett Bowling, Paul Muntner, Joseph E Schwartz, John J Sim, Daichi Shimbo, Kristi Reynolds","doi":"10.1093/ajh/hpag110","DOIUrl":"https://doi.org/10.1093/ajh/hpag110","url":null,"abstract":"<p><strong>Background: </strong>Higher short-term blood pressure (BP) variability (BPV) can reflect impaired autonomic regulation of BP in response to postural change and physical activity, which could precipitate falls through transient cerebral hypoperfusion and loss of postural stability. We hypothesized that higher short-term BPV assessed by ambulatory BP monitoring (ABPM) would be associated with an increased risk of falls.</p><p><strong>Methods: </strong>This prospective study examined the association between BPV assessed by ABPM and fall risk among community-dwelling adults aged ≥65 years with hypertension who were taking antihypertensive medication. Participants completed 24-hour ABPM; subsequently, they completed 12 monthly falls calendars. Systolic BPV was quantified as the standard deviation (SD) of 24-hour systolic BP (SBP) (SD24h-SBP), calculated from the weighted average of awake and asleep SD values. Cox proportional hazards models estimated hazard ratios (HRs) for time to first fall, comparing quartile 4 (Q4) with quartiles 1-3 (Q1-Q3) of SD24h-SBP.</p><p><strong>Results: </strong>Among 608 participants (mean±SD age 74.6±6.2 years; 56.9% female), 238 (39.1%) reported a fall during the 12-month follow-up period. Falls occurred in 172/457 (37.6%) and 66/151 (43.4%) participants in Q1-Q3 and Q4 of SD24h-SBP, respectively. Participants in Q4 of SD24h-SBP did not have a higher fall risk than Q1-Q3 (adjusted HR [95% CI] 1.17 [0.86-1.58]). In analyses using the SDs of awake and asleep SBP, Q4 was not associated with fall risk compared with Q1-Q3.</p><p><strong>Conclusion: </strong>Twenty-four hour and awake BPV assessed by ABPM was not associated with fall risk among older adults taking antihypertensive medication.</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief Office Sodium Screener: Assessing Sodium Intake from High Sodium Foods in the Outpatient Setting.","authors":"Siya Bhagat, Laura Harnish, Susan Devaraj, Valerie Marcellus, Blaise Abramovitz, Evan C Ray, Matthew F Muldoon","doi":"10.1093/ajh/hpag105","DOIUrl":"10.1093/ajh/hpag105","url":null,"abstract":"<p><strong>Background: </strong>Excessive dietary sodium intake contributes to approximately five million deaths annually, mainly due to its association with hypertension and cardiovascular disease. However, healthcare providers have no practicable method to estimate the dietary intake of their patients.</p><p><strong>Methods: </strong>We conceived and developed the Brief Office Sodium Screener (BOSS), a self-administered survey to be completed in three minutes. Using data from the National Health and Nutrition Examination Survey and U.S. Department of Agriculture Food Data Central, high sodium foods (those with ≥300 mg/serving) were compiled into a 30-item survey assessing both frequency and serving size. Automated scoring utilizes the median sodium content per serving, and the report estimates total sodium (mg/day) from high salt sources and the top three contributing items. From September 2023 to August 2024, patients at a tertiary hypertension clinic completed the BOSS and queries about the survey's usability and perceived accuracy during rooming.</p><p><strong>Results: </strong>We included 131 patients; 43% were male, mean age 61 years, range 27-91), and 81% self-identified as white race. The median estimated sodium intake from high sodium foods was 1,699 mg/day (range 0-7,901 mg/day). Top sodium sources were poultry dishes, bread, pasta, and cheese. Among 118 patients who provided feedback, 85% found the BOSS easy to use, 96% felt it was somewhat, moderately or very accurate.</p><p><strong>Conclusions: </strong>The study provides evidence that the BOSS questionnaire is usable and efficient in estimating excessive sodium consumption during outpatient encounters.</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood pressure parameters and cognitive decline and dementia after stroke or transient ischemic attack: results from the PROGRESS trial.","authors":"Sultana Shajahan, Mark Woodward, Craig S Anderson, Cheryl Carcel, Linan Chen, Ruth Peters, Karin Rådholm, Stephen Harrap, John Chalmers, Katie Harris","doi":"10.1093/ajh/hpag056","DOIUrl":"10.1093/ajh/hpag056","url":null,"abstract":"<p><strong>Background: </strong>Besides elevated mean systolic blood pressure (BP), BP variability, pulse pressure (PP), or mean arterial pressure (MAP) could be important targets for dementia prevention. This study investigated these associations in participants with stroke or transient ischemic attack from the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) trial.</p><p><strong>Methods: </strong>BP parameters were calculated from measurements for 18 months on six occasions. Risk of cognitive decline according to Mini-Mental State Examination scores and/or adjudicated dementia outcomes per 1-standard deviation higher for each BP parameter was calculated using modified Poisson regression models with a log link. Subgroup analysis was conducted by mild cognitive impairment (MCI) at baseline, sex, and stroke subtype.</p><p><strong>Results: </strong>Of 5128 participants recruited between May 1995 and November 1997, 567 (11.1%) developed cognitive decline/dementia after 4 (median) years of follow-up until 2001. For systolic BP (SBP), higher mean, maximum, cumulative load, and last measure were associated with higher risk of cognitive decline/dementia, but mean conferred the highest risk (relative risk 1.18, 95% confidence intervals [CIs] 1.06-1.31). For diastolic BP, higher mean, maximum, variability, cumulative load, slope, and last measure were associated, while load showed the strongest association (1.23, 95% CI 1.12-1.36). Only the mean PP was associated (1.11, 95% CI 1.00-1.24). For MAP, MAP load showed the strongest association (1.20, 95% CI 1.09-1.33). Systolic, diastolic, and MAP variability showed a higher risk in those without MCI.</p><p><strong>Conclusions: </strong>Besides mean SBP, higher variability, cumulative load, slope, and last measures of diastolic BP, PP, and MAP were associated with increased risk of cognitive decline/dementia.</p><p><strong>Clinical trial registration: </strong>This trial was not registered because enrollment began before July 1, 2005.</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":"1151-1159"},"PeriodicalIF":2.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13473881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148262858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimated pulse wave velocity predicts outcomes after acute ischemic stroke: a multinational cohort analysis.","authors":"Nikolaos Kakaletsis, Naohisa Hosomi, Tomohisa Nezu, Patrik Michel, Thevoz Guillaume, Davide Strambo, Young Seo Kim, Wonjae Sung, Konstantinos Vemmos, Eleni Korompoki, Maurizio Acampa, Jukka Putaala, Lauri Tulkki, Matthias Hermann, Protazy Rejmer, Philip M Bath, Lisa J Woodhouse, Vasilios Kotsis, Elpida Athanasopoulou, Athanase D Protogerou, Haralampos Milionis, George Ntaios, Christos Savopoulos","doi":"10.1093/ajh/hpag066","DOIUrl":"10.1093/ajh/hpag066","url":null,"abstract":"<p><strong>Background: </strong>Estimated pulse wave velocity (ePWV), an easy to calculate proxy of carotid to femoral PWV (cfPWV), can be derived from 24-hour blood pressure monitoring (24h-BPM). Its role in acute ischemic stroke (AIS) has not previously been investigated in large multinational datasets.</p><p><strong>Methods: </strong>A pooled individual patient data analysis from 13 cohorts across seven countries was conducted, including 2933 AIS patients who underwent 24h-BPM during the hyperacute to subacute phase. ePWV was calculated using a validated equation. Associations with clinical characteristics, stroke severity, etiologic subtypes, and outcomes were assessed with logistic regression. The primary outcome was poor functional outcome at 90 days, defined as a modified Rankin Scale (mRS) >2.</p><p><strong>Results: </strong>Patients with higher ePWV presented with more severe strokes (median NIHSS 7 vs. 3, P < .001) and had poorer outcomes both at 90 days (63.7% vs. 23.7%, P < .001) and discharge (61.9% vs 29.1%, P < .001). ePWV was associated with poor outcome at 90 days (aOR: 1.24, 95% CI: 1.05-1.45) and discharge (aOR: 1.26, 95% CI: 1.12-1.42), per 1 m/s increase in ePWV, after adjustment for conventional risk factors and stroke severity. In patients ≤50 years, ePWV was highest in those with small vessel disease (SVD), who also had more cardiovascular risk factors than other stroke subtypes.</p><p><strong>Conclusions: </strong>ePWV derived from 24h-BPM is a simple, widely applicable measure of vascular aging that is associated with functional outcome after AIS. The higher ePWV observed in young patients with SVD underscores a potential early arteriosclerotic burden in this subgroup.</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":"1142-1150"},"PeriodicalIF":2.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13473874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between the hemoglobin-albumin-lymphocyte-platelet score and all-cause and cardiovascular mortality in adults with hypertension: a National Health and Nutrition Examination Survey cohort study.","authors":"Taotao Zhang, Peiqian Liu","doi":"10.1093/ajh/hpag044","DOIUrl":"10.1093/ajh/hpag044","url":null,"abstract":"<p><strong>Background: </strong>The hemoglobin-albumin-lymphocyte-platelet (HALP) score integrates pathways of anemia, malnutrition, inflammation, and thrombosis that are central to hypertensive organ damage. We therefore hypothesized that HALP would serve as a robust predictor of all-cause and cardiovascular mortality, specifically in adults with hypertension.</p><p><strong>Methods: </strong>This cohort study included 23,564 US adults from National Health and Nutrition Examination Survey (NHANES, 2005-2018), comprising 12,319 with hypertension and 11,245 without, linked to mortality data through 2019. Hypertension was defined as self-reported diagnosis, antihypertensive medication use, or measured blood pressure ≥130/80 mm Hg. Multivariable Cox models and restricted cubic spline analysis were used to assess HALP-mortality associations. Effect modification by hypertension status was formally tested.</p><p><strong>Results: </strong>During a mean follow-up of 7.4 years, 1738 all-cause deaths and 451 cardiovascular deaths occurred among adults with hypertension. In this group, each one-SD higher HALP score was associated with a lower risk of all-cause mortality (HR, 0.89; 95% CI, 0.83-0.94) and cardiovascular mortality (HR, 0.74; 95% CI, 0.65-0.83). In contrast, no association was observed in adults without hypertension (all-cause mortality HR, 0.96; 95% CI, 0.83-1.13; cardiovascular mortality HR, 0.85; 95% CI, 0.65-1.15). An interaction was observed between HALP score and hypertension status for both all-cause (P for interaction = .008) and cardiovascular mortality (P for interaction <.001). Furthermore, restricted cubic spline analysis within the cohort with hypertension revealed L-shaped nonlinear relationships between the HALP score and mortality risks.</p><p><strong>Conclusions: </strong>A higher HALP score was associated with lower mortality risk among adults with hypertension but not among those without hypertension.</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":"1092-1103"},"PeriodicalIF":2.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147866244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"School-based blood pressure measurement and its association with left ventricular mass index among adolescents in urban Tanzania.","authors":"M K Nsanya, R N Peck, T S Masoza, P Ayieko, E C Nyanza, S H Kapiga, C Cichowitz","doi":"10.1093/ajh/hpag104","DOIUrl":"10.1093/ajh/hpag104","url":null,"abstract":"<p><strong>Background: </strong>High blood pressure (BP) among adolescents is increasingly common in sub-Saharan Africa, yet evidence of its association with left ventricular mass index (LVMI) - a key marker of early cardiovascular risk remains limited. We aimed to assess the association between school-based BP measurements and LVMI.</p><p><strong>Methods: </strong>We conducted a cross-sectional study among 210 adolescents in Mwanza City, Tanzania. BP was measured at two visits approximately one week apart. High BP was defined as BP ≥ 120/80 mmHg, according to the 2017 American Academy of Pediatrics guideline. Having high BP at both visits was referred to as sustained high BP.</p><p><strong>Results: </strong>Prevalence of high BP at one and two visits were 18.6%. and 11.9% respectively. Mean (SD) LVMI for participants with normal BP, high BP at one visit, and sustained high BP were 52.9(11.9) g/m2, 57.0(16.5) g/m2 and 60.8(14.9) g/m2 respectively. Sustained high BP was associated with higher LVMI of 6.4 (95% CI: 1.4,11.4) g/m² after adjusting for confounders. Similarly, participants with high BP at only one visit had a 4.5 (95% CI: 0.4,8.6) g/m2 higher LVMI. High sugar consumption (≥ 6 teaspoons/day) was also associated with higher LVMI of 5.4 (95% CI: 0.1,10.7) g/m². Conversely, adequate consumption (≥ 5 servings/day) of fruits and vegetables was associated with lower LVMI of 3.7 (95% CI:0.1, 7.2) g/m².</p><p><strong>Conclusion: </strong>High BP was associated with higher LVMI among apparently healthy Tanzanian adolescents, while fruit, vegetable, and sugar consumption were associated with differences in LVMI, highlighting potential targets for future interventions.</p>","PeriodicalId":7578,"journal":{"name":"American Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}