Rachael Jackson, Katherine Leung, Kristen Matteson
{"title":"Medically assisted reproduction in sexual orientation minority populations.","authors":"Rachael Jackson, Katherine Leung, Kristen Matteson","doi":"10.1016/j.ajog.2026.09.021","DOIUrl":"10.1016/j.ajog.2026.09.021","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlo Antonio Liverani, Carlotta Caia, Veronica Boero
{"title":"Histological outcomes and colposcopic findings in patients with persistent high-risk human papillomavirus infection without major cytological findings (Letter-to-the-Editor).","authors":"Carlo Antonio Liverani, Carlotta Caia, Veronica Boero","doi":"10.1016/j.ajog.2026.08.048","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.08.048","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical-spectrum validation as the next step for cell-free RNA-based preoperative risk stratification of myometrial masses (reply to letter to the editor).","authors":"Aymara Mas, Sören R Stahlschmidt, Carlos Simón","doi":"10.1016/j.ajog.2026.09.014","DOIUrl":"10.1016/j.ajog.2026.09.014","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefano Scarperi, Stefano Ferla, Diego Raimondo, Valentino Bergamini
{"title":"Laparoscopic modified Davydov's technique for vaginoplasty: operative steps and technical pearls.","authors":"Stefano Scarperi, Stefano Ferla, Diego Raimondo, Valentino Bergamini","doi":"10.1016/j.ajog.2026.09.020","DOIUrl":"10.1016/j.ajog.2026.09.020","url":null,"abstract":"<p><p>Müllerian agenesis syndrome is a congenital condition characterized by uterine and vaginal agenesis in women with a normal 46,XX karyotype, normal ovarian function, and normal secondary sexual characteristics. It represents one of the most challenging causes of primary amenorrhea, with significant anatomic, functional, and psychological implications. Several surgical and nonsurgical techniques have been proposed for vaginal reconstruction; however, no universally accepted standard exists. Among surgical options, the laparoscopic Davydov procedure has gained wide acceptance because of its minimal invasiveness and favorable anatomic and functional outcomes. This video article presents a standardized laparoscopic Davydov neovaginoplasty, illustrating key anatomic landmarks and technical steps. We report the case of a 21-year-old woman with Müllerian agenesis, no relevant medical history, and primary amenorrhea, who underwent a combined laparoscopic and vaginal approach. After laparoscopic inspection, the peritoneum between the bladder and rectum was incised, and the rectovesical space was developed. A 12-mm trocar was inserted transperineally to guide the anastomosis of the mobilized peritoneum to the vaginal vestibular mucosa, thereby creating a continuous neovaginal canal. At 6-month follow-up, vaginoscopy showed a well-epithelialized, iodine-positive neovaginal mucosa with a final vaginal length of 11 cm. No urinary or functional complications were reported. This video shows a standardized and teachable laparoscopic technique that may contribute to improving functional and psychosocial outcomes in patients with Müllerian agenesis.</p>","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An uninformative trial, not an equivalent one (Letter-to-the-Editor).","authors":"Hemant Gopalrao Deshpande, Jagriti Gairola, Hariharan Srinivasan","doi":"10.1016/j.ajog.2026.09.023","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.09.023","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interpreting long-term hormone therapy associations after cervical cancer chemoradiotherapy (reply to letter to the editor).","authors":"Ting-Fang Lu, Yu-Hsiang Shih, Chien-Hsing Lu","doi":"10.1016/j.ajog.2026.09.009","DOIUrl":"10.1016/j.ajog.2026.09.009","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does hormone therapy improve multiple outcomes or identify healthier survivors? (letter to the editor).","authors":"Kentaro Iga","doi":"10.1016/j.ajog.2026.09.008","DOIUrl":"10.1016/j.ajog.2026.09.008","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reverse causality or biological effect? A methodological reflection on contraceptive discontinuation research (letter to the editor).","authors":"Wu Ying","doi":"10.1016/j.ajog.2026.09.011","DOIUrl":"10.1016/j.ajog.2026.09.011","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven Habbous, Alinah Surani, Nicholas A Leyland, Ally Murji, Erik Hellsten
{"title":"Uptake and outcomes associated with outpatient hysterectomy in Ontario, Canada.","authors":"Steven Habbous, Alinah Surani, Nicholas A Leyland, Ally Murji, Erik Hellsten","doi":"10.1016/j.ajog.2026.09.018","DOIUrl":"10.1016/j.ajog.2026.09.018","url":null,"abstract":"<p><strong>Objective: </strong>Hysterectomy is the second most common procedure performed among women and is increasingly being performed using minimally invasive techniques. In the this study, we examine the uptake of outpatient hysterectomy in the population of Ontario.</p><p><strong>Study design: </strong>We performed a retrospective population-based cohort study using administrative databases for all elective hysterectomies performed in Ontario, Canada between 2010 and 2024. We estimated the percentage of outpatients admitted and compared outpatients with inpatients on 90-day readmissions, 6-month complications, and 30-day perioperative health system costs. We used logistic regression to evaluate factors associated with the outpatient setting. To evaluate the association of outpatient setting on outcomes, we used propensity weighting.</p><p><strong>Results: </strong>After exclusions, a total of 228,934 patients were included. The number of hysterectomies decreased from 16,484 in fiscal year 2010/2011 to 14,748 in fiscal year 2019/2020, followed by a sharper decline during the COVID-19 pandemic and a recovery by fiscal year 2024/2025, with 16,195 procedures performed. The proportion (and number) of hysterectomies performed in the outpatient setting has increased since 2010, reaching 38% by fiscal year 2024/2025. Since 2021, of the 18,281 procedures with outpatient intent, 15,743 (86%) were completed as outpatient procedures and the remaining 2538 (14%) were subsequently admitted on the procedure date. Outpatients were younger, healthier, received surgery earlier in the day, required less operating time, received total laparoscopic-assisted vaginal hysterectomy (67% vs 27% for inpatients) or total laparoscopic hysterectomy (26% vs 15% for inpatients), and were treated by female surgeons and surgeons with greater experience (P<.0001 for all). There was substantial regional variation in the provision of outpatient hysterectomy, ranging from 0% to 100% across hospitals and surgeons. Outpatients were less likely to be readmitted within 90 days of surgery (readmissions: 676 [3.6%] outpatients vs 2076 [5.4%] inpatients; adjusted risk ratio, 0.83 (95% confidence interval, 0.74-0.93); P=.0009). Between surgery and 30 days postoperatively, outpatient hysterectomy cost the healthcare system $2546 less than inpatient hysterectomy.</p><p><strong>Conclusion: </strong>There has been a substantial uptake of outpatient hysterectomy in Ontario since 2010, with close to 40% of cases being performed as day surgery, with reassuring clinical outcomes and lower health system costs.</p>","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic versus therapeutic thresholds for cervical lesions in persistent high-risk papillomavirus infection (reply to letter to the editor).","authors":"Joona Hulmi, Ilkka Kalliala, Annu Heinonen","doi":"10.1016/j.ajog.2026.09.010","DOIUrl":"10.1016/j.ajog.2026.09.010","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}