American journal of obstetrics and gynecology最新文献

{"title":"Supplement Use and Weight Loss for Polycystic Ovary Syndrome: How Much Weight Should We Give the Information We See on TikTok?","authors":"Rose Darcy,Alison Almgren-Bell,Jessica Almgren-Bell,Sarah Capelouto Cromack,Christina E Boots,Mary Ellen Pavone","doi":"10.1016/j.ajog.2025.09.052","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.052","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"35 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145254579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal Diagnosis and Postnatal Outcomes of a Rare Venous Anomaly: Prominent Azygos Vein with an Uninterrupted Inferior Vena Cava.","authors":"Balaganesh Karmegaraj,Sowmya Vijayakumar","doi":"10.1016/j.ajog.2025.09.048","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.048","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"17 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding the Obstetric Care Conversation in Patients With Intellectual and Developmental Disabilities (Letter-to-the-Editor).","authors":"Lindsey V Grater,Keisha R Callins","doi":"10.1016/j.ajog.2025.09.049","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.049","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"4 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent Isolated Hyperlordosis in the Fetal and Neonatal Period: Clinical Course and Outcome.","authors":"Hana Okamoto,Kuniaki Ota,Toshifumi Takahashi,Yoshiaki Ota,Koichiro Shimoya","doi":"10.1016/j.ajog.2025.09.047","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.047","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"78 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnesium sulfate for the prevention of seizures in preeclampsia: origin, experimental basis, clinical studies, and the evolution in obstetrical practice.","authors":"F Gary Cunningham,David B Nelson","doi":"10.1016/j.ajog.2025.09.045","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.045","url":null,"abstract":"For centuries, convulsions unique to pregnancy have been described. In this time, varying therapies-from phlebotomy to narcotics-have been suggested as the treatment of choice for eclampsia. Building upon the discovery of magnesium salts to control convulsions due to tetanus, magnesium sulfate became a suggested treatment for eclampsia. Throughout the 20th century, several large, clinical trials verified magnesium sulfate as the treatment of choice for eclampsia. In this report, the history of eclampsia management and the study of magnesium sulfate are described. The intent of the report is to highlight the key clinical features with use of magnesium sulfate, the present understanding of the mechanism of action, and the rigor of the studies by which it was established as the current definitive prophylaxis and therapy for eclampsia. Because of the unique pharmacologic properties, it is critical that obstetric providers understand the foundational studies to establish dosing and identified risks with magnesium sulfate application. Additionally, alleged putative effects of magnesium sulfate administration, such as prolongation of labor, are also addressed. Lastly, the challenges with use of magnesium sulfate in the prevention of eclampsia is summarized given the varying definitions of preeclampsia. This report serves as a chronicle to summarize the story of how one of the most commonly utilized agents in obstetrics became the standard of present-day care.","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"121 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Limitations of using national databases to study outcomes in those with disabilities (Reply to Letter-to-the-Editor).","authors":"Noelia Zork,Manasa G Rao,Alexander Friedman","doi":"10.1016/j.ajog.2025.09.050","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.050","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"97 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to 'Breastfeeding after immediate versus delayed postpartum contraceptive implant placement: a non-inferiority randomized controlled trial' American Journal of Obstetrics & Gynecology, In Press Corrected Proof, Published online: March 20, 2025.","authors":"Jamie W Krashin,Maritza Rivera-Montalvo,Lawrence Leeman,Victoria Y Trujillo,Timothy R Petersen,Dominique Sanchez,Emily Bender,Smita Carroll,Erin Bulleit,Jasmin Alcantara,David K Turok,Patricia Black,Eve Espey","doi":"10.1016/j.ajog.2025.08.015","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.08.015","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"157 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145203886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic role of immunohistochemical and molecular markers in no specific molecular profile endometrial cancer: a systematic review and meta-analysis.","authors":"Federico Ferrari,Elisa Gozzini,Lorena Torroni,Matteo Rota,Hooman Soleymani Majd,Cecilia Dell'Avalle,Ferrari Filippo Alberto,Franco Odicino","doi":"10.1016/j.ajog.2025.09.041","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.041","url":null,"abstract":"OBJECTIVENo specific molecular profile (NSMP) endometrial cancer represents nearly half of the diagnoses, characterized by significant molecular heterogeneity and intermediate recurrence and survival outcomes. Currently, no immunohistochemical or molecular markers are established in guidelines to improve prognosis estimation and personalize treatment in NSMP endometrial cancer. This systematic review and meta-analysis aimed to evaluate the prognostic significance of potential immunohistochemical and molecular surrogate markers in NSMP endometrial cancers.DATA SOURCESThis systematic review and meta-analysis adhered to PRISMA guidelines and was registered with PROSPERO (CRD42024601035). A comprehensive literature search was conducted using Scopus, PubMed/MEDLINE, ScienceDirect, and the Cochrane Library (January 1994-December 2024).STUDY ELIGIBILITY CRITERIAStudies assessing the prognostic roles of L1CAM, CTNNB1, ARID1A, estrogen receptor (ER), progesterone receptor (PR), and STATHMIN expression or mutation status in NSMP endometrial cancers were included.STUDY APPRAISAL AND SYNTHESIS METHODSMethodological quality was assessed using the Newcastle-Ottawa Scale (NOS) and the Quality in Prognosis Studies (QUIPS) tool for risk of bias in prognostic studies. Certainty of evidence for each outcome was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. Hazard ratios (HR) for recurrence and survival were calculated using random- or fixed-effects models depending on heterogeneity.RESULTSFourteen retrospective studies including 4,654 NSMP endometrial cancers were analysed. L1CAM overexpression significantly predicted higher recurrence (HR=3.42, 95% CI:1.86-6.29; p<0.001) and worse survival (HR=4.31, 95% CI:2.62-7.09; p<0.001). ER positivity correlated significantly with reduced recurrence risk (HR=0.37, 95% CI:0.26-0.53) and improved survival (HR=0.22, 95% CI:0.17-0.29). Loss of PR expression was associated with increased recurrence and poorer survival outcomes. Conversely, ARID1A and CTNNB1 mutations and STATHMIN1 overexpression did not significantly impact recurrence or survival outcomes.CONCLUSIONSL1CAM overexpression, ER positivity, and PR status demonstrate significant prognostic relevance in NSMP endometrial cancer, warranting consideration as potential markers for improving patient management, including fertility-sparing approach.","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"3 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145203887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Azithromycin for Scheduled Cesareans (Letter-to-the-Editor).","authors":"Alan T N Tita, Brenna L Hughes, Kim Boggess","doi":"10.1016/j.ajog.2025.09.038","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.038","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic Prophylaxis in Obese Patients Undergoing Cesarean Delivery (Reply to Letter-to-the-Editor).","authors":"A B Caughey,P Sultan,Rdw Wilson,G Nelson","doi":"10.1016/j.ajog.2025.09.039","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.09.039","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"53 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}