{"title":"Interpreting the specialist-access gradient in gynecologic cancer stage at diagnosis (Letter-to-the-Editor)","authors":"Wenxuan Sun,Ling Wei","doi":"10.1016/j.ajog.2026.09.042","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.09.042","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"12 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Screening for large-for-gestational-age fetuses: clinical pathways and unintended interventions (Reply to Letter-to-the-Editor)","authors":"Miriam Lopian,Can Ozan Ulusoy,Asma Khalil","doi":"10.1016/j.ajog.2026.10.019","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.10.019","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"13 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Massive Gas Collection in the Upper Female Genital Tract: Physometra with Vaginal Involvement","authors":"Evangelia Christodoulou,Anna-Sofia Garatzioti,Andreas Valsamos","doi":"10.1016/j.ajog.2026.09.039","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.09.039","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"77 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne LEOSTIC,Yoann RODRIGUEZ,Christophe RICHARD,Paul BERVEILLER,Vincent MAUFFRE,Emmanuelle MOTTE-SIGNORET
{"title":"Antenatal oxytocin and respiratory adaptation after prelabor cesarean delivery in late-preterm lambs: a randomized factorial experiment","authors":"Anne LEOSTIC,Yoann RODRIGUEZ,Christophe RICHARD,Paul BERVEILLER,Vincent MAUFFRE,Emmanuelle MOTTE-SIGNORET","doi":"10.1016/j.ajog.2026.10.002","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.10.002","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"36 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Attilio Di Spiezio Sardo,Danilo Borrelli,Serena Guerra,Jose Carugno
{"title":"The Retrograde Migration of Foreign Bodies inside the Female Genital Tract: A Step-by-Step Hysteroscopic Approach","authors":"Attilio Di Spiezio Sardo,Danilo Borrelli,Serena Guerra,Jose Carugno","doi":"10.1016/j.ajog.2026.09.045","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.09.045","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"27 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Ben Saleh,Mirnabi Pirouzifard,Pelle G. Lindqvist,Kristina Sundquist,Bengt Zöller
{"title":"Postpartum Venous Thrombosis in Sweden: A Nationwide Family Study","authors":"Michael Ben Saleh,Mirnabi Pirouzifard,Pelle G. Lindqvist,Kristina Sundquist,Bengt Zöller","doi":"10.1016/j.ajog.2026.10.001","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.10.001","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"20 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ehsan Rojhani, Claudio V Schenone, Ahmed Hashem Fathallah, Nikan Zargarzadeh, Akihiro Hasegawa, Faezeh Aghajani, Eyal Krispin, Francesco D'Antonio, Hiba Mustafa, Asma Khalil, Ramen H Chmait, Alireza A Shamshirsaz
{"title":"Selective Reduction in Monochorionic Pregnancies With Selective Fetal Growth Restriction: A Systematic Review and Meta-analysis.","authors":"Ehsan Rojhani, Claudio V Schenone, Ahmed Hashem Fathallah, Nikan Zargarzadeh, Akihiro Hasegawa, Faezeh Aghajani, Eyal Krispin, Francesco D'Antonio, Hiba Mustafa, Asma Khalil, Ramen H Chmait, Alireza A Shamshirsaz","doi":"10.1016/j.ajog.2026.09.038","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.09.038","url":null,"abstract":"<p><strong>Objective: </strong>To estimate the rates of co-twin intrauterine fetal demise (IUFD), co-twin neonatal demise, and gestational age (GA) at delivery in monochorionic (MC) pregnancies complicated by selective fetal growth restriction (sFGR) undergoing selective reduction (SR) and stratify the outcomes according to the surgical technique.</p><p><strong>Data sources: </strong>PubMed, Embase, Cochrane Library, Scopus, and Web of Science were searched from inception through May 2026.</p><p><strong>Study eligibility criteria: </strong>Studies were eligible if they reported MC pregnancies complicated by sFGR undergoing SR with data on co-twin IUFD or neonatal demise and GA at delivery.</p><p><strong>Study appraisal and synthesis methods: </strong>This systematic review and meta-analysis was conducted per PRISMA guidelines and registered on INPLASY (INPLASY202580001). Pooled estimates were calculated using random-effects meta-analysis, and technique differences were evaluated using meta-analytic tests for subgroup differences. Post hoc binomial generalized linear mixed models (GLMMs) assessed the robustness of dichotomous outcomes without continuity correction. I<sup>2</sup> quantified heterogeneity across studies.</p><p><strong>Results: </strong>A total of 22 studies, including 686 pregnancies, met the inclusion criteria and were eligible for quantitative synthesis. The overall rates of co-twin IUFD and co-twin neonatal death were 15% and 4%, respectively, and the GA at delivery was 35.4 weeks (95% CI, 34.2-36.6). In the primary indirect study-level subgroup analysis, pooled co-twin IUFD was higher in RFA than BCC studies (20% vs 9%; P=0.02). In the GLMM sensitivity analysis, the estimated rates remained higher in RFA than BCC studies (14.8% vs 6.6%), but the subgroup difference was not statistically significant (P=0.06). The only direct within-study comparison included 24 sFGR pregnancies and showed no significant difference in co-twin IUFD (BCC, 0/5; RFA, 3/19; P=1.00). Co-twin neonatal death rates were comparable (BCC, 5% vs RFA, 3%). GA at delivery was lower in cases undergoing BCC compared with RFA (34.5 weeks vs 36.8 weeks, respectively; P=0.039). These unadjusted comparisons may be confounded by differences in study and case characteristics.</p><p><strong>Conclusions: </strong>In MC pregnancies complicated by sFGR undergoing SR, pooled risks of co-twin IUFD and neonatal death were approximately 15% and 4%, respectively. The primary analysis suggested lower co-twin IUFD and earlier delivery in BCC than RFA studies; however, the IUFD difference was not statistically significant in the GLMM sensitivity analysis, and all technique comparisons were indirect, unadjusted, potentially confounded , and the single direct comparison was small and inconclusive. Available evidence does not establish an advantage of BCC or RFA.</p>","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transcervical Balloon Cervical Ripening and Risk of Uterine Rupture After Previous Cesarean Delivery: A Systematic Review and Meta-analysis.","authors":"Jacques Balayla, Allison Engo, Elias M Dahdouh","doi":"10.1016/j.ajog.2026.09.037","DOIUrl":"https://doi.org/10.1016/j.ajog.2026.09.037","url":null,"abstract":"<p><strong>Objective: </strong>To estimate comparator-specific associations between transcervical balloon cervical ripening and complete uterine rupture during trial of labor after cesarean.</p><p><strong>Data sources: </strong>PubMed/MEDLINE, Embase, CINAHL, Cochrane CENTRAL, Web of Science, and Google Scholar were searched from inception through June 2026 without language restriction, plus reference lists and trial registries (PROSPERO CRD420261444368).</p><p><strong>Study eligibility criteria: </strong>Studies of trial of labor after a previous low-transverse cesarean delivery that used a Foley, single-balloon, or double-balloon catheter for cervical ripening were included. Comparative observational studies with spontaneous labor, oxytocin, or prostaglandins as comparators were included in the quantitative synthesis. Amniotomy alone was a prespecified eligible comparator; however, no study reported a separable amniotomy-only arm, precluding quantitative pooling of this comparison. Single-arm cohorts were summarized descriptively, while randomized trials were synthesized qualitatively. Primary analyses were restricted to studies reporting complete uterine rupture separately. Because balloon placement was followed by amniotomy, oxytocin, or both in nearly every protocol, the exposure is designated a balloon-based induction strategy rather than the catheter in isolation.</p><p><strong>Study appraisal and synthesis methods: </strong>Risk of bias was assessed with ROBINS-I, the Newcastle-Ottawa Scale, and Cochrane RoB 2; certainty was rated with GRADE. Comparator-specific odds ratios (ORs) and absolute risk differences were estimated with Mantel-Haenszel methods, with Peto and DerSimonian-Laird models as sensitivity analyses; potentially overlapping Swedish cohorts were not pooled.</p><p><strong>Results: </strong>Eighteen nonrandomized studies and two randomized trials contributed 28,035 study observations, including 5,516 balloon exposures. Relative to prostaglandin induction, balloon ripening showed lower odds of complete uterine rupture across three cohorts (Mantel-Haenszel OR, 0.43; 95% confidence interval [CI], 0.26-0.72; risk difference, -19 per 1,000 [95% CI, -31 to -7] across four cohorts); a potentially overlapping Swedish cohort and a cohort reporting a combined rupture/dehiscence endpoint gave concordant estimates, and one trial recorded no ruptures. No difference was detected versus oxytocin alone (OR, 0.24; 95% CI, 0.05-1.18) or spontaneous labor (seven cohorts; OR, 1.29; 95% CI, 0.90-1.84; OR, 1.09 [95% CI, 0.73-1.62] excluding the most influential cohort). Across all pharmacologic comparators the OR was 0.40 (95% CI, 0.25-0.66), whereas dehiscence was reported more often after balloon-based induction (five studies; OR, 1.86; 95% CI, 1.06-3.29), with concordant estimates against oxytocin-based induction (OR, 1.80; 95% CI, 0.83-3.92), spontaneous labor (OR, 2.24; 95% CI, 0.91-5.52), and prostaglandins (OR, 1.09; 95% CI, 0.15-7.84; P = ","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interpreting the diagnostic performance of angiogenic biomarkers in pregestational diabetes (letter to the editor).","authors":"Yan Chen, Jingyuan Li, Ting Ye","doi":"10.1016/j.ajog.2026.09.035","DOIUrl":"10.1016/j.ajog.2026.09.035","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interpreting angiogenic biomarker profiles in pregestational diabetes as markers of fetal risk (reply to letter to the editor).","authors":"Ruth C E Hughes, Jonathan A Williman, Gene Lee","doi":"10.1016/j.ajog.2026.09.030","DOIUrl":"10.1016/j.ajog.2026.09.030","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}