Chirurgisches Forum fur experimentelle und klinische Forschung最新文献

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[Deuterium oxide (D2O)--a protective factor for cellular stabilization in hypothermic preservation of the liver? (author's transl)]. 氧化氘(D2O)——低温保存肝脏中细胞稳定的保护因子?(作者的transl)]。
J H Fischer, M Fuhs, M Miyata, M Wenzel, W Isselhard
{"title":"[Deuterium oxide (D2O)--a protective factor for cellular stabilization in hypothermic preservation of the liver? (author's transl)].","authors":"J H Fischer,&nbsp;M Fuhs,&nbsp;M Miyata,&nbsp;M Wenzel,&nbsp;W Isselhard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rat livers were preserved by ischemic hypothermic storage in extra- or intracellular type solutions for 24 h. A substitution of 85% of the tissue water by deuterium oxide (D2O) resulted in increased glycolytic energy production, better maintenance of the energy potential of the cells but a higher AMP loss, and a reduction of edema formation. Preservation using \"retrograde oxygen persufflation\" (ROP) resulted in optimal maintenance of the metabolic state which could be further influenced positively by D2O in the total nucleotide content.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"129-33"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18041430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Oral application of bacterial vaccine for infection prophylaxis (author's transl)]. [口服细菌疫苗预防感染的应用(作者译)]。
Chirurgisches Forum fur experimentelle und klinische Forschung Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-67617-8_15
J. Seifert, G. Urbach, G. Lob
{"title":"[Oral application of bacterial vaccine for infection prophylaxis (author's transl)].","authors":"J. Seifert, G. Urbach, G. Lob","doi":"10.1007/978-3-642-67617-8_15","DOIUrl":"https://doi.org/10.1007/978-3-642-67617-8_15","url":null,"abstract":"","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":"33 2","pages":"73-7"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51017058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Experimental occlusion of the superior mesenteric artery: further evidence of the influence of histamine and diamine oxidase in the development of shock (author's transl)]. [实验性肠系膜上动脉闭塞:组胺和二胺氧化酶在休克发展中的影响的进一步证据[作者简介]。
C D Stahlknecht, J Kusche, A Schmal, W Lorenz
{"title":"[Experimental occlusion of the superior mesenteric artery: further evidence of the influence of histamine and diamine oxidase in the development of shock (author's transl)].","authors":"C D Stahlknecht,&nbsp;J Kusche,&nbsp;A Schmal,&nbsp;W Lorenz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In shock produced by temporary superior mesenteric artery occlusion the plasma histamine concentration was enhanced following release of the mesenteric blockade. Furthermore, an inhibition of the diamine oxidase catalysed histamine inactivation resulted in an aggravation of the shock development. These processes, already shown in dogs and mini pigs, were also observed in rabbits. Histamine receptor antagonists abolished the effect of the enhanced histamine concentration appearing in the circulation following inhibition of diamine oxidase. In human intestinal tract a fairly similar distribution of histamine and diamine oxidase was found as in the mammals studied. Thus the indicated pathobiochemical processes should be reckoned with in patients suffering from circulatory disorders of the intestinal tract.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"267-70"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17824136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Early or delayed operation in patients with acute cholecystitis. Results of a prospective randomized controlled clinical trial (author's transl)]. 急性胆囊炎患者的早期或延迟手术。一项前瞻性随机对照临床试验的结果[作者简介]。
D Schaefer, H Barth, K Thon, L Jostarndt, D Maroske
{"title":"[Early or delayed operation in patients with acute cholecystitis. Results of a prospective randomized controlled clinical trial (author's transl)].","authors":"D Schaefer,&nbsp;H Barth,&nbsp;K Thon,&nbsp;L Jostarndt,&nbsp;D Maroske","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a prospective controlled randomized clinical trial, 60 patients with acute cholecystitis (diagnosed according to well defined criteria) were allocated randomly to early operation (n=28) or conservative treatment followed by delayed operation (n=30). The formed groups were well balanced. Total duration of hospitalization was 12 days for the early and 22 days for the delayed operation group. One case of death in the second group appeared to be due to pancreatic necrosis. From other complications recorded, only stitch sinus seemed to occur more frequently in the early operation group. For the first time the success of the two therapeutic procedures was evaluated by means of a systematic follow-up 6 weeks and 6 months after operation. The outcome was the same in both groups and \"very good\" and \"good\" for all patients. From these results early operation as the routine method for acute cholecystitis can be recommended unconditionally.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"149-53"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18040281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The influence of prostacyclin on gastrointestinal blood flow during hypovolemic shock (author's transl)]. [低血容量性休克时前列环素对胃肠道血流的影响[作者简介]。
R Jakesz, M Starlinger, P Bratusch-Marrein, R Schiessel, M Schemper
{"title":"[The influence of prostacyclin on gastrointestinal blood flow during hypovolemic shock (author's transl)].","authors":"R Jakesz,&nbsp;M Starlinger,&nbsp;P Bratusch-Marrein,&nbsp;R Schiessel,&nbsp;M Schemper","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of a continuous PGI 2 infusion on blood flow of various organs was tested in normovolemia and in hemorrhagic shock. PGI 2 increased the blood flow of stomach, pancreas and jejunum in normovolemic animals. The reduced blood flow due to hemorrhagic shock was increased to preshock values in stomach, pancreas, and jejunum. A linear correlation was found between the dose of PGI 2 and mucosal blood flow of the stomach.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"227-31"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18040283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Charles Brenton Huggins, Nobel Prize for Medicine 1966: "Discovery is our business"]. 查尔斯·布伦顿·哈金斯,1966年诺贝尔医学奖:“发现是我们的事业”。
D Schmähl
{"title":"[Charles Brenton Huggins, Nobel Prize for Medicine 1966: \"Discovery is our business\"].","authors":"D Schmähl","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"VI-VIII"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18041425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Action of cyclosporin A and cytimun on the survival time of accessory heart transplants (author's transl)]. [环孢素A和cytimun对副心脏移植存活时间的影响[作者译]。
W Timmermann, R Y Calne, D J White, D White, A Thiede
{"title":"[Action of cyclosporin A and cytimun on the survival time of accessory heart transplants (author's transl)].","authors":"W Timmermann,&nbsp;R Y Calne,&nbsp;D J White,&nbsp;D White,&nbsp;A Thiede","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The new immunosuppressive substances Cyclosporin A (group A = 15 mg) and Cytimun = ASTA 5122 (group B = 15 mg, group C = 5 mg) were tested in rats that received accessory cervical heart transplants. A syngeneic (DA leads to DA) and a strongly allogeneic (PVG leads to DA) strain combination served as controls of operative and immunogenetic parameters. Whereas Cyclosporin A (group A) brought about a local transplant tolerance in 90% of cases, at a dosage of 15 mg/kg per day (group B), Cytimun led in 88% of cases to lethal intoxication of the recipients. At a dosage of 5 mg/kg per day (group C), 67% of the animals survived; however, they showed electrocardiographic evidence of possible temporary rejection crises between the 5th and the 13th day.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"139-43"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18041432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cement-free fixation of a stemless total knee endoprosthesis in animal experiments (author's transl)]. [动物实验中无骨水泥固定无柄全膝关节假体[作者简介]。
R Heimel, K D Richter, M Taayedi, Z Esmail
{"title":"[Cement-free fixation of a stemless total knee endoprosthesis in animal experiments (author's transl)].","authors":"R Heimel,&nbsp;K D Richter,&nbsp;M Taayedi,&nbsp;Z Esmail","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A stemless total knee endoprosthesis with physiological kinematics (slip and rolling motion, tibial rotation) and cement-free primary fixation (straddling dowel and thread system) was tested in animal experiments. The fixation allows total functioning of the operated extremity from the first day after operation. Primary results and follow-up for 40 weeks after operation reveal satisfactory results, especially with regard to durable bony incorporation of the prosthesis as shown by histologic and microangiographic studies.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"41-6"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18399286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[In vivo synthesis of cartilage after transplantation of chondrocytes in animal experiments (author's transl)]. [动物实验中软骨细胞移植后软骨的体内合成(作者译)]。
G Helbing, C Burri, W Heit, R Neugebauer, A Rüter
{"title":"[In vivo synthesis of cartilage after transplantation of chondrocytes in animal experiments (author's transl)].","authors":"G Helbing,&nbsp;C Burri,&nbsp;W Heit,&nbsp;R Neugebauer,&nbsp;A Rüter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Long-term results after cartilage transplantation are not satisfactory owing to poor viability of the chondrocytes. In vitro experiments with isolated fetal and neonatal rabbit chondrocytes revealed a much better proliferative ability compared with adult cartilage derived cells. Cryopreservation of cell suspensions did not decrease the proliferative ability. In in vivo experiments, cultured neonatal, fetal, and cryopreserved rabbit chondrocytes were tested in transplants and compared with cell-free controls or radiated chondrocytes. These chondrocytic transplants showed good viability and seemed to synthesize cartilage matrix, which could be stained with safranin, whereas only fibrous tissue was found in controls.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18399287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Does i.v. gamma globulin counteract postoperative bacterial infections? (authors's transl)]. 静脉注射丙种球蛋白能抵抗术后细菌感染吗?(作者的transl)]。
K H Duswald, K Müller, J Seifert, J Ring
{"title":"[Does i.v. gamma globulin counteract postoperative bacterial infections? (authors's transl)].","authors":"K H Duswald,&nbsp;K Müller,&nbsp;J Seifert,&nbsp;J Ring","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A prospective, randomized clinical study investigated the effectiveness of IV gamma-globulin (GG) against bacterial infections after surgical procedures. As a result of 20 g GG IV, given postoperatively, the average concentration decrease for IgG (25% - 30%) could be balanced as soon as the third postoperative day, the local infection rate was decreased in the low-risk group, and, with the occurrence of long-lasting local infections, the number of patients with simultaneous septic complications was lowered.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"61-5"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17221926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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