Biomaterials, medical devices, and artificial organs最新文献_第7页

Evaluation of collagen crosslinking techniques. 胶原交联技术的评价。

Biomaterials, medical devices, and artificial organs Pub Date : 1983-01-01 DOI: 10.3109/10731198309118815

K Weadock, R M Olson, F H Silver

{"title":"Evaluation of collagen crosslinking techniques.","authors":"K Weadock, R M Olson, F H Silver","doi":"10.3109/10731198309118815","DOIUrl":"https://doi.org/10.3109/10731198309118815","url":null,"abstract":"The properties of collagen films crosslinked by physical and chemical techniques were compared to the properties of films crosslinked with glutaraldehyde (GTA). Physical techniques studied include exposure to short wave (254 nm) u.v. irradiation and severe dehydration. Chemical techniques studied include immersion of collagen films in aqueous solutions of cyanamide or GTA. Collagen films exposed to combinations of aqueous solutions of cyanamide and severe dehydration had moduli of elasticity, swelling ratios and resistance to bacterial collagenase similar to films crosslinked with GTA. Theoretical calculations based on amino acid composition indicate that approximately seven times as many amino acid residues are capable of forming crosslinks using cyanamide or severe dehydration procedures as compared to GTA crosslinking. In addition, using severe dehydration or cyanamide forms crosslinks involving both amino and carboxyl residues which may allow these procedures to act synergistically. Based on our studies this two-step procedure effectively crosslinks collagen-based biomaterials while the only by-product of this reaction is water-soluble urea. Preliminary biocompatibility studies suggest that this crosslinking procedure may allow for pronounced tissue ingrowth.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"11 4","pages":"293-318"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198309118815","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17158868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 323

Experimental attempts to reduce acrylic cement porosity. 实验尝试降低丙烯酸水泥孔隙率。

Biomaterials, medical devices, and artificial organs Pub Date : 1983-01-01 DOI: 10.3109/10731198309118808

J C Keller, E P Lautenschlager

引用次数: 8

A comparison of the mechanical properties of Simplex, Zimmer, and Zimmer low viscosity bone cements. Simplex、Zimmer和Zimmer低粘度骨水泥力学性能的比较。

Biomaterials, medical devices, and artificial organs Pub Date : 1983-01-01 DOI: 10.3109/10731198309118789

S C Weber, W L Bargar

{"title":"A comparison of the mechanical properties of Simplex, Zimmer, and Zimmer low viscosity bone cements.","authors":"S C Weber, W L Bargar","doi":"10.3109/10731198309118789","DOIUrl":"https://doi.org/10.3109/10731198309118789","url":null,"abstract":"Many different methods have been used to compare polymethylmethacrylate bone cements. In this paper the three currently available cements were compared in regard to dough and set times, heat of polymerization, compressive, tensile, 3 and 4 point bending strengths, fracture toughness, flexural modulus, void density distribution, and viscosity. Methods used were ASTM designated for bone cement or plastics in general whenever possible. Significant differences in set and dough times and heat of polymerization were noted. All cements were equal in compressive, tensile, and fracture toughness testing; Zimmer Regular Cement was significantly weaker (p less than 0.001) in flexural testing and had a significantly (p less than 0.001) decreased modulus of elasticity when compared to LVC and Simplex Cements. Void density distributions were not significantly different. Viscosity was shown to vary between these cements as well. This data was analysed both to determine differences between various brands of cement and to assess the relevance to clinical use and failure modes in vivo of these different means of testing.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"11 1","pages":"3-12"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198309118789","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17671922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

The use of the mouse peritoneal cavity for screening for biocompatibility of polymers. 利用小鼠腹腔筛选聚合物的生物相容性。

Biomaterials, medical devices, and artificial organs Pub Date : 1983-01-01 DOI: 10.3109/10731198309118799

R S Wortman, K Merritt, S A Brown

引用次数: 4

Histologic and microradiographic evaluation of textured and nontextured aluminum oxide dental implants. 有织构和无织构氧化铝牙种植体的组织学和显微放射学评价。

Biomaterials, medical devices, and artificial organs Pub Date : 1983-01-01 DOI: 10.3109/10731198309118812

S D Cook, R C Anderson, C J Lavernia

引用次数: 2

Problems and challenges of biomaterials in cardiovascular applications: a status report. 生物材料在心血管应用中的问题和挑战:现状报告。

Biomaterials, medical devices, and artificial organs Pub Date : 1983-01-01 DOI: 10.3109/10731198309118813

S D Bruck

{"title":"Problems and challenges of biomaterials in cardiovascular applications: a status report.","authors":"S D Bruck","doi":"10.3109/10731198309118813","DOIUrl":"https://doi.org/10.3109/10731198309118813","url":null,"abstract":"Biomaterials used as implants and in various devices must exhibit long-term (years) compatibility with the physiological environment, including blood, and additionally must also remain stable to perform mechanical functions, excepting applications where biodegradation is required. This paper focuses on problems and challenges of polymeric materials in contact with blood in the following categories: (1) artificial heart valves, (2) cardiovascular assist devices and artificial hearts, (3) vascular prostheses, and (4) the biological evaluation of materials prior to their human use, especially with respect to species related hematological differences of experimental animals. Besides thrombosis (which is the most obvious consequence of incompatibility), the calcification of chemically treated tissue prostheses as well as synthetic elastomers used in many cardiovascular devices is discussed in terms of biochemical and physico-chemical parameters together with its significance in long-term (years) implant applications. Complement activation brought about by contact of blood with foreign surfaces has received less than deserved attention in the evaluation of biomaterials and devices, despite the potentially serious problems. Relative ignorance in selecting appropriate animals for the biological evaluation of biomaterials whose hematological profiles and behavior of platelets, red and white cells to trauma and response to foreign surfaces differ decisively from those of humans, often leads to less than meaningful predictions for eventual clinical uses. The state-of-art realities are examined in conjunction with medical, societal, ethical, and economic boundaries.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"11 4","pages":"271-80"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198309118813","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17445645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Thermal characterization of electrosurgery. 电手术的热特性。

Biomaterials, medical devices, and artificial organs Pub Date : 1983-01-01 DOI: 10.3109/10731198309118798

T S Neiman, B Dunn, J E Flocken

引用次数: 0

Metal allergy, metal implants and fracture healing. 金属过敏，金属植入物和骨折愈合。

Biomaterials, medical devices, and artificial organs Pub Date : 1983-01-01 DOI: 10.3109/10731198309118796

S A Brown, S D Devine, K Merritt

引用次数: 7

Protein adsorption in vitro onto biomaterial surfaces covered with ULTI carbon. 蛋白质在体外吸附于覆盖ULTI碳的生物材料表面。

Biomaterials, medical devices, and artificial organs Pub Date : 1982-01-01 DOI: 10.3109/10731198209118780

H S Borovetz, G E Molek, G Levine, R L Hardesty, A D Haubold

引用次数: 3

Evaluation of fluids' effect on dental composite. 液体对牙科复合材料影响的评价。

Biomaterials, medical devices, and artificial organs Pub Date : 1982-01-01 DOI: 10.3109/10731198209118767

P Sung, A Torgalkar

引用次数: 0