Biomaterials, medical devices, and artificial organs最新文献_第10页

Properties of agarose-encapsulated adsorbents. II. Elimination of endogenous and exogenous phenolic compounds from human serum. 琼脂糖包封吸附剂的性能研究。2从人血清中消除内源性和外源性酚类化合物。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109118996

C J Holloway, K Harstick, G Brunner, E Neumann

{"title":"Properties of agarose-encapsulated adsorbents. II. Elimination of endogenous and exogenous phenolic compounds from human serum.","authors":"C J Holloway, K Harstick, G Brunner, E Neumann","doi":"10.3109/10731198109118996","DOIUrl":"https://doi.org/10.3109/10731198109118996","url":null,"abstract":"Phenolic compounds derived from the amino acid tyrosine are endogenous toxins, which are believed to be involved in the pathogenesis of hepatic coma. There are also xenobiotic phenolic substances, such as p-hydroxy-acetanilide (paracetamol or acetaminophen), which can lead to serious complications if taken in an overdose. In both cases, a drastic therapeutic measure such as haemoperfusion may be indicated to eliminate the toxin from the blood. In the present work, human serum has been dosed with the phenolic compounds of immediate relevance in exogenous and endogenous intoxication, and the effectiveness of various adsorbent materials for the elimination of the toxins from the serum has been investigated. Resins and charcoal in the native state have been compared with those encapsulated into large agarose beads, a process which improves the haemocompatibility and thus the practicability of the adsorbents. A certain degree of specificity has been observed. Whereas phenolic acids are adsorbed quite effectively onto the strongly basic ion exchange resins of the Dowex 1X type, particularly 1X8 or 2X8, phenol or paracetamol are less effectively eliminated. In contrast to many other classes of toxin, the Amberlite XAD-type resins are ineffective for all the phenolic substances investigated. Charcoal is the most effective adsorber in most cases, particularly when encapsulated in powder form into agarose beads.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"9 2","pages":"149-63"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198109118996","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18273066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Evaluation of reconstituted collagen tape as a model for chemically modified soft tissues. 重建胶原带作为化学修饰软组织模型的评价。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109117599

K E Bluel, T A Saul, D J Lentz, S L Woo

{"title":"Evaluation of reconstituted collagen tape as a model for chemically modified soft tissues.","authors":"K E Bluel, T A Saul, D J Lentz, S L Woo","doi":"10.3109/10731198109117599","DOIUrl":"https://doi.org/10.3109/10731198109117599","url":null,"abstract":"In the last decade a number of chemically fixed, soft tissue based bioprostheses have become commercially available. Chemical fixation of these materials changes a number of their physical and chemical properties. Quantitation of these effects has been difficult because of: anisotropy of the biopolymers, variable composition of the materials, and sample size and configuration limitations. Collagen tape, made from reconstituted collagen, has been chosen as a model material because it alleviates many of the aforementioned problems. Its constituent fibers are homogeneous and unidirectional. The cross-sectional area is constant. Thus, the resultant uniaxial tensile stress-strain relationship is reproducible to allow for systematic parametric studies. Results are presented for the change in tensile properties of the collagen tape as a function of exposure time to glutaraldehyde fixative. These properties are described by the equation: sigma = A (eB epsilon-1) The tensile properties of fresh and fixed pericardial tissue were also tested and corroborative results were found.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"9 1","pages":"37-46"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198109117599","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18274994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vivo and in vitro considerations of corrosion testing. 体内和体外腐蚀试验的考虑。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109117601

S A Brown, K Merritt

引用次数: 15

Effect of postcuring on hemo-compatibility of silicone rubber. 后固化对硅橡胶血液相容性的影响。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109119002

T Devanathan, K A Young

引用次数: 9

Analysis of bone-composite interfacial strengths. 骨-复合材料界面强度分析。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109117600

C M Davis, J F Shackelford

引用次数: 1

Rheology of acrylic bone cements. 丙烯酸骨水泥流变学研究。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109119001

J L Ferracane, E H Greener

引用次数: 9

Healing of femoral osteotomies with plastic plate fixation. 股骨截骨塑料钢板固定治疗。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109117598

S A Brown, J Vandergrift

引用次数: 16

Suggestions for a total elasto-dynamic intervertebral disc prosthesis. 建议采用全弹性动力椎间盘假体。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109117602

H G Edeland

引用次数: 29

Bidirectional subminiature thermistor sensor for analog control by breath flow. 用于呼吸流量模拟控制的双向微型热敏电阻传感器。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109117603

A Sekey, C Seagrave

引用次数: 0

Mechanical behavior of the femoral head in Legg-Perthes disease. Legg-Perthes病股骨头的力学行为。

Biomaterials, medical devices, and artificial organs Pub Date : 1981-01-01 DOI: 10.3109/10731198109117597

J S DeNatale, G T Rab, L R Herrmann

{"title":"Mechanical behavior of the femoral head in Legg-Perthes disease.","authors":"J S DeNatale, G T Rab, L R Herrmann","doi":"10.3109/10731198109117597","DOIUrl":"https://doi.org/10.3109/10731198109117597","url":null,"abstract":"The research described herein is concerned with the development of a \"restricted\" three-dimensional finite element model of the femoral head that permits the mechanical behavior of the hip joint in Legg-Perthes' disease to be simulated and studied. This \"restricted\" finite element model allows the femoral head to be treated as a non-axisymmetrically loaded axisymmetric solid of revolution. In order to minimize computer costs, and in recognition of the several uncertainties present in the mechanical description of the system, a number of simplifying assumptions are introduced. These assumptions include an axisymmetric geometry, axisymmetric and linear-elastic material properties, small deformation and displacement, and an approximate load distribution on the femoral head. The computer analyses reveal the relation between the magnitude and the distribution of the stresses in the femoral head and such parameters as (1) the position in the gait cycle, (2) the thickness of the articular cartilage, (3) the extent of the necrotic bone, and (4) the type of corrective osteotomy. A sampling of the preliminary results is presented and some conclusions are drawn with respect to the implications of the study.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"9 1","pages":"19-26"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198109117597","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18274992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2