Biomaterials, medical devices, and artificial organs最新文献_第2页

A new sutureless method for the anastomosis of blood vessels. 一种新的无缝线血管吻合方法。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118842

J J Wozniak

引用次数: 6

Post-sintering heat treatments for porous coated Ti-6A1-4V alloy. 多孔涂层Ti-6A1-4V合金的烧结后热处理。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118841

S D Cook, E A Renz, R J Haddad

引用次数: 3

Characterisation of a polyester material for biomedical applications. 生物医学用途聚酯材料的特性。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118846

P D Nair, K Sreenivasan, M Jayabalan

引用次数: 1

Pyridoxylated polyhemoglobin as a red cell substitute for resuscitation of lethal hemorrhagic shock in conscious rats. 吡哆酰化多血红蛋白在清醒大鼠致死性失血性休克复苏中的红细胞替代物。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118839

P E Keipert, T M Chang

{"title":"Pyridoxylated polyhemoglobin as a red cell substitute for resuscitation of lethal hemorrhagic shock in conscious rats.","authors":"P E Keipert, T M Chang","doi":"10.3109/10731198509118839","DOIUrl":"https://doi.org/10.3109/10731198509118839","url":null,"abstract":"In our previous work, pyridoxylated polyhemoglobin (PP-PolyHB) was shown to have a P50 = 16-18 torr, and a half-life (T 1/2) of 20 hrs in the circulation of rats given a 75% isovolemic exchange transfusion. For the present study, a rapid and lethal hemorrhagic shock model has been specifically designed to assess the ability of PP-PolyHB to function as an emergency resuscitation fluid. Using 48 fully conscious rats with special chronic arterial and venous cannulations, shock was induced by bleeding 67% of total blood volume in less than 40 min; producing 100% mortality in nonresuscitated controls. Resuscitation was carried out using one of the following infusion fluids equivalent in volume to the bled volume: Ringer's solution, albumin solution, stroma-free Hb (SFHb), pyridoxylated SFHb (PP-SFHb), PP-PolyHb, and whole blood. Long-term (greater than 8 day) survival rate of rats (n = 12) resuscitated with PP-PolyHb was 75% compared to 83% for autologous whole blood. Survival following resuscitation with the other fluids was substantially lower. These results indicate that PP-PolyHb could effectively resuscitate lethal hemorrhagic shock in conscious rats, and provide long-term survival afterwards, even in the absence of any additional fluid maintenance.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"13 1-2","pages":"1-15"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198509118839","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15196937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 35

Microencapsulation and controlled release of insulin from polylactic acid microcapsules. 聚乳酸微胶囊胰岛素的微胶囊化与控释。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118850

S Y Lin, L T Ho, H L Chiou

{"title":"Microencapsulation and controlled release of insulin from polylactic acid microcapsules.","authors":"S Y Lin, L T Ho, H L Chiou","doi":"10.3109/10731198509118850","DOIUrl":"https://doi.org/10.3109/10731198509118850","url":null,"abstract":"Insulin has been encapsulated in biodegradable polylactic acid microcapsules and non-biodegradable ethylcellulose microcapsules by using an emulsification-solvent evaporation process. Gelatin and polyvinylalcohol were used as protective colloids. The concentrations and types of protective colloids affecting the micromeritic properties and release behavior of insulin microcapsules were studied. The higher the concentration of protective colloids the smaller the particle size of microcapsules. The median diameter of microcapsules decreased with the increase of the viscosity of protective colloids. Scanning electron microscopic observations suggested that microcapsules prepared from higher concentrations of polyvinylalcohol solution resulted in a nonporous and compact surface on the microcapsules, compared to the porous microcapsules prepared from gelatin solution. The residual crystals and porous structure of microcapsules affected the release rate of microcapsules. After the initial burst effect the release rate of insulin from microcapsules was found to be constant, so that prolonged release was obtainable. Three percent of polyvinylalcohol was the best choice for the preparation of polylactic acid microcapsules.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"13 3-4","pages":"187-201"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198509118850","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15030076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 36

Liquid covering for superficial skin wounds and its effect on wound closure in guinea pigs. 豚鼠浅表皮肤创面的液体覆盖物及其对伤口愈合的影响。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118840

K S Stenn, S P Yan

引用次数: 5

Experimental application of polyvinyl alcohol-silica for small artificial vessels. 聚乙烯醇-二氧化硅在小型人工血管中的实验应用。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118847

K Tamura, H Mizuno, K Okada, H Katoh, S Hitomi, T Teramatsu, Y Shimizu, T Hino

{"title":"Experimental application of polyvinyl alcohol-silica for small artificial vessels.","authors":"K Tamura, H Mizuno, K Okada, H Katoh, S Hitomi, T Teramatsu, Y Shimizu, T Hino","doi":"10.3109/10731198509118847","DOIUrl":"https://doi.org/10.3109/10731198509118847","url":null,"abstract":"Polyvinyl alcohol-silica (PVA-SiO2) composite and heparinized PVA-SiO2 were examined in vitro and in vivo as materials to coat artificial vessels to be used for the replacement of small arteries. PVA-SiO2 was observed to prolong coagulation time and on heparinized PVA-SiO2 surfaces no blood coagulation was noticed after a period of two days using the Lee-White and plasma recalcification methods. After placing non-coated and coated surfaces in contact with blood components in vitro and in vivo, the degree of blood component adhesion was greater in non-coated woven Dacron than in PVA-SiO2 coated Dacron. The degree of adhesion was even less in heparinized PVA-SiO2 coated Dacron. Furthermore, artificial vessels made of these 3 types of materials were used to replace parts of the canine abdominal aorta and were removed one and a half years later. Patency rates were as follows: non-coated 2/7, PVA-SiO2-coated 4/7, heparinized PVA-SiO2-coated 8/12. The inner surfaces of these prostheses were observed with light microscopy and scanning electron microscopy. Intima formation was thinner on the PVA-SiO2 composite surfaces than on the control surfaces. Heparin acted as a local anticoagulant and PVA-SiO2 limited intima formation. This report showed that PVA-SiO2 composite coated surfaces can be effective for small artery replacement due to good tissue affinity and anticoagulability.","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"13 3-4","pages":"133-52"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198509118847","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14151995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

3-D femoral stress analysis using CT scans and p-version FEM. 三维股骨应力分析采用CT扫描和p型有限元法。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118849

P K Basu, A G Beall, D J Simmons, M Vannier

引用次数: 16

Liposome-type artificial red blood cells stabilized with carboxymethyl chitin. 羧甲基几丁质稳定脂质体型人工红细胞。

Biomaterials, medical devices, and artificial organs Pub Date : 1985-01-01 DOI: 10.3109/10731198509118843

A Kato, I Tanaka, M Arakawa, T Kondo

引用次数: 18

Contact angle at solid-water octane interface. 固-水辛烷界面接触角。

Biomaterials, medical devices, and artificial organs Pub Date : 1984-01-01 DOI: 10.3109/10731198409118829

A K Nair, C P Sharma

引用次数: 2