V Colletti, F G Fiorino, L Saccetto, N Giarbini, M Carner
{"title":"Improved auditory performance of cochlear implant patients using the middle fossa approach.","authors":"V Colletti, F G Fiorino, L Saccetto, N Giarbini, M Carner","doi":"10.3109/00206099909073026","DOIUrl":"https://doi.org/10.3109/00206099909073026","url":null,"abstract":"<p><p>The preliminary results of insertion of a cochlear implant via the middle fossa in nine patients with profound bilateral hearing loss are described. Aetiologies included a bilateral radical mastoidectomy cavity, adhesive otitis media, autoimmune inner ear disease, previous cranial trauma, genetic pre-lingual deafness, and otosclerosis. A classic middle fossa approach was adopted. A small cochleostomy measuring 1.5 mm in diameter was performed on the most superficial part of the basal turn. A Nucleus 24M cochlear implant system (Cochlear Corporation) was inserted in four patients, a Lauraflex implant (Philips Hearing Implants) was used in three patients and a Combi 40+ (Med-el) with a double electrode array in two. Single electrode arrays were inserted from the cochleostomy to the cochlear apex and occupied a portion of the basal turn, as well as the middle and apical turns. Double electrode arrays were inserted, one towards the apex and one into the basal turn of the cochlea towards the round window. The receiver stimulator was positioned in a bone well previously drilled in the temporal squama and the electrode carrier was inserted in the fenestrated cochlea. The activity of the inserted electrodes was tested by means of telemetry and intraoperative recording of electrically evoked auditory brainstem responses (EABR). Speech recognition tests, performed over a period of time ranging from one to six months after cochlear implant activation, yielded better results in these patients compared with those obtained in postlingually deaf patients operated on via the traditional transmastoid route. Cochlear implant insertion via the middle fossa approach is a technique which is suitable for the implantation of patients with bilateral radical mastoidectomy cavities, chronic middle ear disease, middle ear malformations, or with partial obliteration of the cochlea in the basal turn. However, the main advantage of inserting the implant through the middle fossa cochleostomy consists in the possibility of stimulating, with the single array, areas of the cochlea, i.e. part of the basal, middle and apical turns, where a greater survival rate of spiral ganglion cells is known to occur. In addition, with the double array total occupation of the cochlea is possible, providing the possibility of replicating the tonotopic organization of the cochlea. This new approach has led to major improvements in speech recognition in all patients compared with patients operated on via the transmastoid approach and, given the present state of the art, may be the elective approach for optimal implantation outcomes.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 4","pages":"225-34"},"PeriodicalIF":0.0,"publicationDate":"1999-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21297118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M C Langereis, A J Bosman, A F van Olphen, G F Smoorenburg
{"title":"Intelligibility of vowels produced by post-lingually deafened cochlear implant users.","authors":"M C Langereis, A J Bosman, A F van Olphen, G F Smoorenburg","doi":"10.3109/00206099909073025","DOIUrl":"https://doi.org/10.3109/00206099909073025","url":null,"abstract":"<p><p>The present study addresses the effect of cochlear implantation on the intelligibility of vowels produced by 20 post-lingually deafened Dutch subjects. All subjects received the Nucleus-22 cochlear implant (3 WSP and 17 MSP processors). Speech recordings were made pre-implantation and three and twelve months post-implantation with the implant switched on and off. Vowel intelligibility (monophthongs only) was determined using a panel of listeners. For all implanted subjects intelligibility was measured in a noisy background. For seven poorly speaking subjects it was also measured in a quiet background. After implantation with the Nucleus-22 device the results showed that vowel intelligibility, measured for all subjects in a noisy background, increased for most of them (about 15), while it increased for about half the number of poorly speaking subjects measured in a quiet background. Twelve months after implantation vowel intelligibility, measured for all subjects in noise, appeared to be based on first and second formant information. This was also found for the subgroup of seven subjects performing poorly pre-implantation when analysed separately. However, vowel intelligibility for this subgroup, when measured in a quiet background, was based also on vowel duration. The differences between the overall result in noise and the results of the subgroup in quiet should be attributed mainly to the noise and not to aspects of poor speech production in the subgroup. In addition, this study addresses the relationship between the intelligibility scores and objective measurements of vowel quality performed in a previous study. The results showed that the vowel intelligibility scores are mainly determined by the position of the second formant frequencies.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 4","pages":"206-24"},"PeriodicalIF":0.0,"publicationDate":"1999-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21297123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of click evoked otoacoustic emissions in newborns: effects of time-windowing.","authors":"G Tognola, F Grandori, P Ravazzani","doi":"10.3109/00206099909073014","DOIUrl":"https://doi.org/10.3109/00206099909073014","url":null,"abstract":"<p><p>The objective of this study was to investigate the effects of time-windowing on click evoked otoacoustic emissions (CEOAEs); 466 CEOAEs from full-term babies were considered. Data were acquired according to the default ILO88 response window (2.5-20 ms). Because CEOAEs are time-varying signals, each emission was analysed by means of the wavelet transform (WT), a technique which allows a simultaneous representation of the time and frequency features of a signal. By means of the WT it was possible to extract the temporal pattern of the elementary frequency components of the compound emissions. The effects of time-windowing were evaluated on each single emission component: rms and correlation values were computed from six 2.5-ms long time windows in the 2.5-17.5 ms range. Results indicated that both rms and correlation were not constant with time but reached a maximum in specific time-windows, depending on the frequency of the component. For low-frequency components, the correlation typically had a maximum in the interval 10-12.5 ms, whereas high-frequency components had a maximum around 5 ms. Above 12.5 ms, the correlation was greatly decreased for all frequency components. As a result, the comparison between the performance of the default ILO88 window (2.5-20 ms) and the window 2.5-12.5 ms showed that for all frequencies in the 1.5-6 kHz range there was a statistically significant improvement in the correlation. No improvement was observed for frequencies below 1.5 kHz because of their contamination by the residual background noise.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 3","pages":"127-34"},"PeriodicalIF":0.0,"publicationDate":"1999-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21302151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Kunst, H Marres, P Huygen, G Van Camp, F Joosten, C Cremers
{"title":"Autosomal dominant non-syndromal low-frequency sensorineural hearing impairment linked to chromosome 4p16 (DFNA14): statistical analysis of hearing threshold in relation to age and evaluation of vestibulo-ocular functions.","authors":"H Kunst, H Marres, P Huygen, G Van Camp, F Joosten, C Cremers","doi":"10.3109/00206099909073018","DOIUrl":"https://doi.org/10.3109/00206099909073018","url":null,"abstract":"<p><p>A Dutch kindred was studied with low-frequency sensorineural hearing impairment linked to a new locus on chromosome 4p16 (DFNA14). Of the affected individuals, 21 (aged 11-75 years) were examined and the most recent audiogram was used for cross-sectional analysis of hearing threshold in relation to age. Suitable serial audiograms were available for a longitudinal analysis in nine cases: they had been obtained from the age of six years onwards and covered a follow-up period from 14 to 36 years. The presumably congenital (offset) component of SNHI was extrapolated or estimated from average values and offset thresholds were found of about 45 dB at 0.25-1 kHz, 25 dB at 2 kHz and 10 dB at 4-8 kHz. Significant progression in hearing impairment occurred at all frequencies, but could be attributed to presbyacusis. The combination of congenital, stationary low-frequency SNHI and presbyacusis resulted in an up-sloping audiogram in the first five decades of life, which evolved into a flat-type audiogram in the sixth or seventh decade and a down-sloping audiogram at a more advanced age. With few exceptions, vestibular function was intact.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 3","pages":"165-73"},"PeriodicalIF":0.0,"publicationDate":"1999-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21302156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study of the effects of cochlear loss on the auditory brainstem response (ABR) specificity and false positive rate in retrocochlear assessment.","authors":"D R Watson","doi":"10.3109/00206099909073017","DOIUrl":"https://doi.org/10.3109/00206099909073017","url":null,"abstract":"<p><p>The auditory brainstem response (ABR) test is widely used as a screen for retrocochlear dysfunction in individuals suffering idiopathic auditory and vestibular disturbance. Although its sensitivity for lesions of the lower brainstem is well established, hearing loss is known to have significant effects upon the test's specificity and false positive rate. This study analysed the effects of aspects of cochlear hearing loss including level, slope and general audiogram shape on these properties of the ABR test in a large clinical group. The study comprised 306 patients (153 male, 153 female) referred for ABR screening to exclude retrocochlear dysfunction. Of 566 ears meeting the inclusion criteria, 85 (15 per cent) failed the test. On follow-up eight ears (3 per cent) were confirmed to have some form of retrocochlear abnormality, seven of which were pathological. All had abnormal ABR results. No cases of retrocochlear abnormality were found in the ABR pass group. In those patients diagnosed as free of retrocochlear problems, the importance of the I-V interval as a primary index of function was confirmed. It displayed a high specificity (>90 per cent) which was largely independent of the level or slope of high-frequency hearing loss. In contrast wave V specificity decreased with increasing loss and increasing slope. Its value as a functional index was limited with losses greater than 70 dB HL in whom specificity fell below 70 per cent. The study concluded that, despite reducing interval availability above 60 dB HL, wave V latency cannot be used as an alternative index because it displays weakening specificity over this range of loss. With the problems inherent in applying latency corrections, the author advocates the use of improved procedures for wave I identification in these cases.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 3","pages":"155-64"},"PeriodicalIF":0.0,"publicationDate":"1999-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21303398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The prognostic value of electrocochleography in severely hearing-impaired infants.","authors":"R Schoonhoven, P J Lamoré, J A de Laat, J J Grote","doi":"10.3109/00206099909073016","DOIUrl":"https://doi.org/10.3109/00206099909073016","url":null,"abstract":"<p><p>This paper presents a longitudinal evaluation of electrocochleographic assessment in severely hearing-impaired infants. Electrophysiological data were obtained by transtympanic electrocochleography to tone-burst stimuli at octave frequencies of 500 to 8000 Hz at the age of 0-6 years in a group of 126 subjects. The results are compared with auditory thresholds determined at school age in the same children by means of pure-tone audiometry. Cochlear microphonics could be recorded in virtually all ears, although the majority of subjects had hearing losses of 90 dB and more. Compound action potentials (CAPs) showed waveforms varying from normal to a wide range of abnormalities. Audiometric thresholds correlated generally well with the compound action potential (CAP) thresholds obtained in infancy. The error in the predicted audiometric thresholds is between 15 and 20 dB, as compared with 11 dB reported for more moderate hearing losses. It is shown that, in spite of the high stimulus levels used, substantial frequency-specific threshold information is retained. Occasional large discrepancies in thresholds were often associated with markedly abnormal response waveforms. Among the many cases in which no ABR could be elicited, 68 per cent produced detectable electrocochleographic responses in the 1000-4000 Hz range. It is concluded that electrocochleography is a valuable method for the assessment of residual hearing in infants suspected of having a severe hearing impairment.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 3","pages":"141-54"},"PeriodicalIF":0.0,"publicationDate":"1999-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21302850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comparison of extratympanic versus transtympanic recordings in electrocochleography.","authors":"Y Noguchi, H Nishida, A Komatsuzaki","doi":"10.3109/00206099909073015","DOIUrl":"https://doi.org/10.3109/00206099909073015","url":null,"abstract":"<p><p>Detection thresholds, amplitudes and input output curves of cochlear microphonics (CMs), and action potentials (APs) determined by extratympanic electrocochleography (ET ECochG) were compared with those determined by transtympanic (TT) ECochG in the same ears. Two groups were studied: 12 ears in 9 volunteers with normal hearing, and 6 ears in 6 subjects with sensorineural hearing loss. Short tone bursts with frequencies of 0.5, 1, 2 and 4 kHz were used as acoustic stimuli to evoke CMs, and a click was presented to measure the APs. In both groups, although the two approaches produced large differences in amplitudes, nearly identical values were obtained for the CM and AP detection thresholds. The CM and AP input-output curves obtained from mean amplitudes at each intensity in normally-hearing ears had similar slopes with the two approaches. These findings demonstrate the clinical usefulness of ET ECochG.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 3","pages":"135-40"},"PeriodicalIF":0.0,"publicationDate":"1999-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21302153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Quaranta, P Portalatini, M Camporeale, V Sallustio
{"title":"Effects of salicylates on evoked otoacoustic emissions and remote masking in humans.","authors":"A Quaranta, P Portalatini, M Camporeale, V Sallustio","doi":"10.3109/00206099909073019","DOIUrl":"https://doi.org/10.3109/00206099909073019","url":null,"abstract":"<p><p>The aim of this study was to evaluate, in young volunteer subjects, the effects of salicylates on evoked otoacoustic emissions (EOAEs), which presumably reflect an active mechanical process in the cochlea due to outer hair cell (OHC) activity, and on remote masking (RM), which has been proposed as a useful tool in the study of the non-linear cochlear distortion products generated by high-frequency maskers. Data from the present research are consistent with the literature showing a reversible effect of salicylate leading to elevated hearing thresholds and reduced EOAE amplitudes. From the point of view of new findings, the results demonstrate a reversible effect of salicylates on RM magnitude, which decreases as serum salicylate concentration increases. As described previously by other authors, salicylate selectivity inhibits OHC motility and, in consequence, reduces the amplitude of the motion of the basilar membrane. According to these data it is very likely that the observed reduction in RM magnitude after salicylate administration is also the result of the decreased ability of the OHCs to contract and of the reduced basilar membrane motion. The results are consistent with the conclusion that the OHC system function plays a role in producing RM.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 3","pages":"174-9"},"PeriodicalIF":0.0,"publicationDate":"1999-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21302155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transient evoked otoacoustic emissions in laboratory animals.","authors":"R Khvoles, S Freeman, H Sohmer","doi":"10.3109/00206099909073013","DOIUrl":"https://doi.org/10.3109/00206099909073013","url":null,"abstract":"<p><p>Transient evoked otoacoustic emissions (TEOAEs) are much used clinically. However, it has been difficult to record them in small laboratory animals, and experimental manipulations designed to determine the generation mechanisms of this type of emission could not be performed. After refining the technique, based on the use of short clicks and a short amplifier gain suppression period, TEOAEs were recorded using the same instrumentation and techniques in rabbits, Psammomys obesus (fat sand rats), mice, rats and guinea pigs. Distortion product emissions were also recorded. The responses in each species differed with respect to threshold, magnitude, frequency spectrum and duration (endpoint). The ability to record TEOAEs routinely in laboratory animals should now allow for further experimentation on the mechanisms of their generation, on the cochlear amplifier in general and on the comparison of TEOAEs with distortion product emissions in individual species and animals.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 3","pages":"121-6"},"PeriodicalIF":0.0,"publicationDate":"1999-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21302851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between the uncomfortable loudness level and the acoustic reflex threshold for pure tones in normally-hearing and impaired listeners--a meta-analysis.","authors":"S O Olsen","doi":"10.3109/00206099909073004","DOIUrl":"https://doi.org/10.3109/00206099909073004","url":null,"abstract":"<p><p>The objective of this study was to determine the potential of the acoustic reflex threshold (ART) as a predictor of the uncomfortable level (ULL) and to identify related areas for investigations in the future. Eleven studies reporting data from 141 normally-hearing and 240 impaired hearing subjects have been reviewed, focusing on methods, test conditions and subjects. Results and conclusions are discussed and new calculations have been performed on the reported data. The median difference between ART and ULL across studies and frequencies was 5 dB both in normally-hearing and impaired subjects. Some authors argue, that although a close relationship of mean values of the two measurements may exist, prediction of the ULL based on ART measurement will be inaccurate because of high inter-subject variability. A statistically significant correlation exists between the mean HTL, the mean ART and the mean ULL in impaired hearing, while a relationship between the mean ART and the mean ULL does not exist in normal hearing. Based on pooled data across frequencies from the reviewed studies the mean ULL= (0.64 x mean ART+38) dB HL. The discrepancies between the results found in the reviewed studies may be explained by different instructions and stimulus presentation orders when assessing the ULL, difficulty in assessing the sound pressure level in the ear canal, influence of varying background noise levels and different admission criteria. It is recommended that the relationship between different loudness levels and the ART be investigated in normally-hearing subjects and in subjects with different levels of impairment, using standardized instructions. To further provide uniformity of the test material groups should be selected according to history of middle ear diseases and the use of hearing aids.</p>","PeriodicalId":75571,"journal":{"name":"Audiology : official organ of the International Society of Audiology","volume":"38 2","pages":"61-8"},"PeriodicalIF":0.0,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00206099909073004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21077709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}