Archivos de investigacion medica最新文献_第4页

Gallstones in the golden hamster. XXXVI. Pigment cholelithiasis produced by retinoic acid. 金仓鼠的胆结石。38。视黄酸引起的色素胆石症。

Archivos de investigacion medica Pub Date : 1991-04-01

R Cárdenas, M E Jaime, L Guzmán, H Granados

{"title":"Gallstones in the golden hamster. XXXVI. Pigment cholelithiasis produced by retinoic acid.","authors":"R Cárdenas, M E Jaime, L Guzmán, H Granados","doi":"","DOIUrl":"","url":null,"abstract":"Previously we have reported on the pigmentary lithogenic action of vitamin A in the form of retinol acetate. In the present work the possible lithogenic action of retinoic acid was tested, since this differs from retinol in several metabolic aspects, which can contribute to the understanding of the pathogenesis of the pigment cholelithiasis produced by vitamin A. Two experiments were performed in which the lithogenicity of retinol acetate added to a colony chow at the level of 25,000 IU%, was compared with that of 3 dietetic levels of all-trans retinoic acid. In the first experiment seric triglycerides were determined in order to establish whether there is a relation between the hypertriglyceridemic effect of retinoids and their lithogenicity; in the second experiment GPT and GOT were determined as indicators of hepatotoxicity. The results showed that the retinoic acid at levels of 24,000 and 35,000 IU% of diet, produced a cholelithiasis incidence similar to that of 25,000 IU% of retinol acetate, whereas the retinoic acid level of 12,000 IU% was not lithogenic. The dietetic retinoic acid produced a reduction of hepatic vitamin A, that was directly proportional to the level supplied. There was no relation between the hypertriglyceridemic effect of retinoids and its lithogenicity. The retinoids produced a light increase in GPT, which was higher with retinol acetate, whereas GOT had not significative changes. It is concluded that all-trans retinoic acid produces pigment gallstones in the hamster, with an incidence similar to that produced by retinol acetate.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"22 2","pages":"209-16"},"PeriodicalIF":0.0,"publicationDate":"1991-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12982185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Valvular dysfunction due to the obstruction of the ventricular catheter caused by cysticercus cyst. 囊虫囊肿引起的心室导管阻塞引起的瓣膜功能障碍。

Archivos de investigacion medica Pub Date : 1991-04-01

M Sandoval, I Madrazo, J A García-Rentería, J A Maldonado, O López-Camacho

引用次数: 0

Evaluation of the hypothalamic-hypophyseal axis in patients with hypertensive hydrocephalus due to neurocysticercosis. 神经囊虫所致高血压脑积水患者下丘脑-垂体轴的评价。

Archivos de investigacion medica Pub Date : 1991-04-01

I Madrazo, M Sandoval, D González

引用次数: 0

Studies on the medicinal properties of Solanum chrysotrichum in tissue culture: I. Callus formation and plant induction from axillary buds. 黄曲茄药用特性的组织培养研究:1 .腋芽愈伤组织形成及植株诱导。

Archivos de investigacion medica Pub Date : 1991-04-01

M L Villarreal, J Muñoz

引用次数: 0

Frequency of identification of cytotoxigenic strains of Escherichia coli in cases of diarrhea from rural and urban communities. 农村和城市腹泻病例中大肠埃希菌产细胞毒素菌株的检出频率。

Archivos de investigacion medica Pub Date : 1991-04-01

N R Parra-Maldonado, J Torres-López, M Camorlinga-Ponce, S Giono-Cerezo, S González-Arroyo, O Muñoz-Hernández

{"title":"Frequency of identification of cytotoxigenic strains of Escherichia coli in cases of diarrhea from rural and urban communities.","authors":"N R Parra-Maldonado, J Torres-López, M Camorlinga-Ponce, S Giono-Cerezo, S González-Arroyo, O Muñoz-Hernández","doi":"","DOIUrl":"","url":null,"abstract":"It has been suggested that strains of Escherichia coli producing Vero-Toxin (VTEC) may cause diarrhea or hemorrhagic colitis; however, there are not enough studies to support this hypothesis. We studied the frequency of isolation of VTEC strains in patients with acute diarrhea from rural and urban communities. A total of 1430 strains were analyzed, 361 coming from 118 patients from the rural community (Cadereyta, Qro.) and 1069 from the urban district (D.F.); 95 of these patients were asymptomatic, 213 suffered from watery diarrhea and 43 had bloody diarrhea. For production of toxins, strains were grown in tryptic soy broth for 24h and the culture supernatant was inoculated on HeLa cells; strains were considered cytotoxic when they caused lysis in at least 50% of the cells. In the rural community, VTEC strains were isolated in 20% of the asymptomatics, in 45% of the watery diarrhea patients and in 76% of patients with bloody diarrhea. Frequency of isolation was significantly higher in patients with diarrhea than in asymptomatics (P less than 0.05). The relative risk to present watery diarrhea was 3 and to present bloody diarrhea was 12. In the urban district, VTEC strains were isolated in 13, 7.9 and 4.5% from asymptomatics, watery diarrhea and bloody diarrhea patients, respectively; the relative risk for diarrhea was 1. Colonization by VTEC strains is significantly higher in patients from the rural community and these infected patients have an important risk to develop diarrhea.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"22 2","pages":"217-22"},"PeriodicalIF":0.0,"publicationDate":"1991-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12981330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human leukocyte migration inhibition factor (LIF) increases polymorphonuclear cell endocytosis. 人白细胞迁移抑制因子(LIF)增加多形核细胞内吞作用。

Archivos de investigacion medica Pub Date : 1991-01-01

M A Cortés-Castillo, L Favila-Castillo

引用次数: 0

Invasive amebiasis in a spider monkey (Ateles geoffroyi). Case report and a short review of the literature of amebiasis in non-human primates. 蜘蛛猴的侵袭性阿米巴病。非人类灵长类阿米巴病病例报告及文献综述。

Archivos de investigacion medica Pub Date : 1991-01-01

H Márquez-Monter, R Fuentes-Orozco, I Correa-Lemus, I Becker

{"title":"Invasive amebiasis in a spider monkey (Ateles geoffroyi). Case report and a short review of the literature of amebiasis in non-human primates.","authors":"H Márquez-Monter, R Fuentes-Orozco, I Correa-Lemus, I Becker","doi":"","DOIUrl":"","url":null,"abstract":"A spider monkey (Ateles geoffroyi) studied at the San Juan de Aragon Zoo died with symptoms of amoebic dysentery verified by coprologic investigation of the parasite, his female partner was cured with conventional antiamoebic treatment. At autopsy widespread ulcerations in the colon and multiple liver abscesses were found, containing trophozoites of Entamoeba histolytica. Both lesions were identical to those observed in human amoebiasis. A short review of the literature in nonhuman primates infections points out that the so-called spontaneous amoebiasis seen in colonies of captive monkeys, and transmission to their newborns within the same species of monkeys, have been in contact with humans. It is proposed that amoebiasis in monkeys should be considered as an excellent model for experimental studies on amoebiasis because other phylogenetically distant species have shown different pathology or are resistant to the infection. Also, it should raise concern that monkeys may become carriers of cysts and trophozoites of virulent strains of E. histolytica. Entamoeba histolytica DNA hybridization techniques should be considered for comparing genomic similarities with other protozoa, including the genera Amoeba to establish its pattern of evolution.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"22 1","pages":"75-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12981660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The antigenic structure of Mycobacterium tuberculosis examined by immunoblot and ELISA. Influence of the age of the culture and of the obtaining method on the composition of the antigenic extracts. 免疫印迹和酶联免疫吸附法检测结核分枝杆菌的抗原结构。培养时间和获取方法对抗原提取物组成的影响。

Archivos de investigacion medica Pub Date : 1991-01-01

C Espitia, I Cervera, R Mancilla

{"title":"The antigenic structure of Mycobacterium tuberculosis examined by immunoblot and ELISA. Influence of the age of the culture and of the obtaining method on the composition of the antigenic extracts.","authors":"C Espitia, I Cervera, R Mancilla","doi":"","DOIUrl":"","url":null,"abstract":"In this study we have examined by immunoblot (IB) and enzyme-linked immunosorbent assay (ELISA) the humoral immune response in pulmonary tuberculosis. As a previous step, in an attempt to obtain the optimal antigen preparation for these studies, the influence of the culture age and of the obtention method on the composition of the extracts was analyzed. The highest number of antigenic bands was found in culture filtrates of 6 and 8 weeks; at these times two thick bands of 65 and 63 kilodaltons (kDa) were identified. These bands were absent from younger and older cultures. When analyzing the source of antigens, we found that culture filtrates contained more antigenic bands than sonic extracts. In view of these findings, culture filtrates of 6 weeks of age were used as test antigens. With 19 tuberculous sera a total of 16 antigenic bands were observed by IB. The response was very heterogeneous with respect to the intensity of the detected reactions and the number of reacting bands. The most frequently recognized bands were those of 31, 32, 38, 58 and 94 kDa. By ELISA with 49 tuberculous sera and with 48 control sera, a specificity of 0.98 and a sensitivity of 0.70 were obtained.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"22 1","pages":"101-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12981708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hodgkin's disease. A historical perspective. 何杰金氏病。历史的视角。

Archivos de investigacion medica Pub Date : 1991-01-01

A Avilés, J C Díaz-Maqueo, V Torras, J R Ayala, H D Cortés

{"title":"Hodgkin's disease. A historical perspective.","authors":"A Avilés, J C Díaz-Maqueo, V Torras, J R Ayala, H D Cortés","doi":"","DOIUrl":"","url":null,"abstract":"Two hundred and sixty-four patients with Hodgkin's disease (HD) forming the basis of our 15 year experience are retrospectively analyzed. Three therapeutic periods are recognizable. 1. The 1974-76 period was characterized by the increasing knowledge of staging procedures and therapeutic approaches. The 81 patients treated in this period experience 67 and 60% survival at 5 and 10 years, respectively. 2. The 1977-80 period was characterized by a large combination of MOPP and radiotherapy. The 87 patients who entered this period experienced 75 and 72% survival at 5 and 10 years, respectively. 3. The last therapeutic period 1981-84 is characterized by the increasing relevance of prognostic factors and alternating the use of MOPP and ABVD as non-cross resistant regimen. The 96 patients who entered this period showed 96% survival at 4 years. Both survival and disease-free survival were positively influenced by the change of therapeutic strategies during the three periods (p less than .005). Although better results have been recorded moving from one to the next therapeutic period, the present policy has been also based on the recognition of a high number of late complications due to therapy. Preliminary results about the present therapeutic experience seem to indicate both a good remission rate and low incidence of complications.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"22 1","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12889808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in cardiac repolarization and ventricular conduction in a case of acute hematomyelia. Report of a case. 急性血液病1例心脏复极和心室传导的变化。报告一个病例。

Archivos de investigacion medica Pub Date : 1991-01-01

T Corona-Vázquez, B Estañol-Vidal, A Abundes-Velasco

引用次数: 0