Archivos de investigacion medica最新文献_第10页

[Mast cells in Peyer's patches in the mouse]. [小鼠佩耶氏斑中的肥大细胞]。

Archivos de investigacion medica Pub Date : 1990-04-01

J Ventura-Juárez, S González-Pérez, R A Jarillo-Luna, R Campos-Rodríguez

{"title":"[Mast cells in Peyer's patches in the mouse].","authors":"J Ventura-Juárez, S González-Pérez, R A Jarillo-Luna, R Campos-Rodríguez","doi":"","DOIUrl":"","url":null,"abstract":"Mast Cells participate in immediate and late hypersensitivity activities, immunoregulation and inflammation. Recently two groups of them have been detected on the basis to its morphology, content of granules and function: a) Those who are localized in connective tissue and b) Those of the intestinal mucosa. Those of the intestinal mucosa are T dependent and proliferate in parasitic as well as in intestinal hypersensitivity conditions to diverse antigens, in turn, Peyer's Patches (PP) are considered antigen catcher and initiators of intestinal immune responses; these are subject to the influence of diverse substances, several of which are within mast cells (for example: histamine, prostaglandins, etc); for which in this work we investigate the morphology relation between PP and mast cells. Balb/c mice small intestine segments with muscular layer and PP of proximal, middle and distal levels where studied; were histologically processed, toluidine blues stained and mast cells counted in different intestinal layers (PP underlying zone, rest of the muscular, corium and submucosa. Data were analyzed by the paired double T test for mean differences. A greater Quantity of mast cells were observed at the marginal zone of the PP in comparison to the rest of the muscular layer, submucosa and corium. The abundance of mast cells in relation to the PP possibly indicates its modulatory influence on the function of lymphoid cells of the PP.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 2","pages":"139-43"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13258695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Identification of inborn errors of galactose metabolism in patients with cataracts]. 【白内障患者先天性半乳糖代谢错误的鉴定】。

Archivos de investigacion medica Pub Date : 1990-04-01

G Vaca-Pacheco, C Medina, D García-Cruz, J Sánchez-Corona, E Chávez-Anaya, C Jaimes, A Hernández-Córdova

引用次数: 0

[Granulocyte-macrophage colony-stimulating factor in the treatment of secondary bone marrow suppression in patients with lymphoma. Preliminary report]. 粒细胞-巨噬细胞集落刺激因子在淋巴瘤患者继发性骨髓抑制中的作用。初步报告)。

Archivos de investigacion medica Pub Date : 1990-04-01

A Avilés, J C Díaz-Maqueo, A Talavera, E L García

引用次数: 0

Neurotoxicity of thallium: biochemical and morphological study of organic lesions. 铊的神经毒性:器质性病变的生化和形态学研究。

Archivos de investigacion medica Pub Date : 1990-04-01

R Barroso-Moguel, C Ríos-Castañeda, J Villeda-Hernández, M Méndez-Armenta, S Galván-Arzate

{"title":"Neurotoxicity of thallium: biochemical and morphological study of organic lesions.","authors":"R Barroso-Moguel, C Ríos-Castañeda, J Villeda-Hernández, M Méndez-Armenta, S Galván-Arzate","doi":"","DOIUrl":"","url":null,"abstract":"A biochemical study of experimental thallium intoxication in newborn rats and its morphological consequences upon the brain of developing animals was undertaken. The thallium content was analyzed in the following encephalic regions: hippocampus, hypothalamus, mesencephalon, cerebellum, and cortex. One day after application of the toxic substance, a homogeneous distribution of the metal in the brain was found. Thallium concentrations in the mentioned regions were twice as high as those found in an adult rat, at the same dosage, 20 newborn Wistar rats were used for the histopathological study. 5 remained as witnesses, the rest received a single injection of thallium of .07 ml. of a solution with a concentration of .32 mg/Kg. 3 rats were sacrificed at 24, 48 and 72 hours; 3 at 7 days and 3 at 51 days. The brain , sciatic and crural nerves were fixated in 10% formaldehyde for 15 days. Cuts in paraffin and frozen sections measuring between 5 and 7 microns were taken from the fragments of different areas. These were stained with aniline methods (Masson, Gallego and H-E) and silver-gold impregnation as modified by Río-Hortega.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 2","pages":"115-22"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13258724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Usefulness of chromosomal heteromorphisms obtained by G-banding for identification of illegitimacy]. [通过g带获得的染色体异型在鉴别私生子女的有用性]。

Archivos de investigacion medica Pub Date : 1990-04-01

S Armendares, L Buentello, F Salamanca, R Lisker

引用次数: 0

[Effect of in vitro infection with dengue virus (DEN-2) on various cellular immune response functions in the mouse]. [体外感染登革病毒(DEN-2)对小鼠多种细胞免疫应答功能的影响]。

Archivos de investigacion medica Pub Date : 1990-04-01

A E Islas-Rodríguez, J Ramos, C Ramos

{"title":"[Effect of in vitro infection with dengue virus (DEN-2) on various cellular immune response functions in the mouse].","authors":"A E Islas-Rodríguez, J Ramos, C Ramos","doi":"","DOIUrl":"","url":null,"abstract":"When Dengue type 2 virus (DEN-2) is put in contact with spleen cells from DBA/2 mice that had been stimulated with Concanavalin A, it was found a decrease in the incorporation of (3H) Thymidine. Furthermore it was observed that the number of Antibody forming cells (Plaque forming cells) against SRBC was decreased, when lymphocytes from DBA/2 mice spleen in culture, had been stimulated with sheep red blood cells (SRBC) in vitro and then infected with DEN-2 virus and the interleukin-1 (IL-1) biosynthesis was quantified in the thymocyte system it was shown that macrophages produced high levels of IL-1 compared with non-infected cells, and that this increased levels could be similar to that produced when macrophages are stimulated with lipopolysaccharide form E. Coli (LPS). The above mentioned results suggest that DEN-2 virus is able of altering some functions of the immune response concerning T and B lymphocytes. Furthermore, the infection of P388D1 cells induce in the first 24 hours an over production of IL-1 that could be the reason why in the natural infection in humans, patients run a fever in the beginning of the viremia caused by DEN-2 virus related with the property of IL-1 reported as endogenous pyrogen.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 2","pages":"87-93"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13258543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obstruction of the ventricular catheter of a CSF shunt system due to the own cyst of Taenia solium. 由于猪带绦虫自身囊肿导致脑脊液分流系统的脑室导管阻塞。

Archivos de investigacion medica Pub Date : 1990-04-01

M Sandoval, I Madrazo, J A García-Rentería, J A Maldonado, O López-Camacho

引用次数: 0

[C-peptide measurement in patients with type II diabetes mellitus: its possible use in the insulin therapy decision]. [2型糖尿病患者c肽测定:在胰岛素治疗决策中的可能应用]。

Archivos de investigacion medica Pub Date : 1990-04-01

H E Tamez-Pérez, C García-Vallejo, R Santos-Flores, P M González-Martínez, L Lojero-Wheatley, S Valdovinos-Chávez

{"title":"[C-peptide measurement in patients with type II diabetes mellitus: its possible use in the insulin therapy decision].","authors":"H E Tamez-Pérez, C García-Vallejo, R Santos-Flores, P M González-Martínez, L Lojero-Wheatley, S Valdovinos-Chávez","doi":"","DOIUrl":"","url":null,"abstract":"Considering pancreatic reserve recognition a more rational basis for starting insulin therapy in NIDDM, during 1988 we studied fasting and post-breakfast plasma C-peptide levels in 31 patients (21 w, 10 m, mean age 48.2 +/- 17.7 yr), referred to our department for insulin therapy evaluation because of primary or secondary failure to other measures. Major features were obesity and chronically uncontrolled illness. Our patients were categorized as follows: group A, considered non responders which included four patients; group B, taken as responders consisting in seven; and a remaining of 20 hyperresponsive patients which formed group C; these with patients of group B, embodied an 87.1% of patients. Among nonresponders there was no any case of total B cell loss of function, and plasma C-peptide activity surpassed through those limits considered for ketoacidosis. We believe that these patients should be eligible candidates for insulin therapy. We failed to found out correlation of plasma C-peptide activity with either age or duration of illness. Our observation supports that fasting plasma C-peptide evaluation would suffice for pancreatic reserve evaluation. We conclude that our patients mainly presented an insulin resistant state associated with obesity thus enhancing the commonplace call for reinforcing nonpharmacologic treatment modalities such as caloric restriction, weight loss and exertion to achieve a better control in NIDDM patients.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 2","pages":"123-6"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13258723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Human fetal homograft to the nigrostriatal system for the treatment of Parkinson's disease]. [人类胎儿同型移植到黑质纹状体系统治疗帕金森病]。

Archivos de investigacion medica Pub Date : 1990-04-01

I Madrazo, R Franco-Bourland, F Ostrosky, M Aguilera, C F Cuevas, H Castrejón, G Guízar-Sahagún, E Magallon

{"title":"[Human fetal homograft to the nigrostriatal system for the treatment of Parkinson's disease].","authors":"I Madrazo, R Franco-Bourland, F Ostrosky, M Aguilera, C F Cuevas, H Castrejón, G Guízar-Sahagún, E Magallon","doi":"","DOIUrl":"","url":null,"abstract":"Four cases of transplant to the brain (striatum) of the ventral mesencephalic area (VMA) and three adrenal glands (A) to patients with Parkinson's disease are described as a new alternative for the improvement of this disease. The patients who received VMA showed a very significant improvement in the rigidity, bradykinesia, alterations in walking and posture, as well as the facial expression. Three of the four patients have returned to work. The group that received A tissue, showed a discreet improvement in the rigidity and bradykinesia, but none in the other signs of the disease. These patients are able to accomplish their daily needs, but two are unable to return to work. The differences which we observed between patients receiving VMA and A transplants, might be related to the heterogeneity of the disease, although we believe that the type of graft was responsible of these differences. Our results with the use of VMA, as well as that of other groups, are encouraging, although it is important to clearly establish that it is a procedure which is still in an experimental phase, requiring caution, and should only be practiced in highly qualified centers of clinical research.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 2","pages":"201-7"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13258542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Flow characteristics in 3 kinds of heart valve prosthesis]. 3种心脏瓣膜假体的血流特性

Archivos de investigacion medica Pub Date : 1990-04-01

J Espino-Vela, A Bobadilla-Aguirre, G Muñoz-Hernández, S Reyes-Rodríguez, J Meraz-Campillo, L Sáenz-Arroyo

{"title":"[Flow characteristics in 3 kinds of heart valve prosthesis].","authors":"J Espino-Vela, A Bobadilla-Aguirre, G Muñoz-Hernández, S Reyes-Rodríguez, J Meraz-Campillo, L Sáenz-Arroyo","doi":"","DOIUrl":"","url":null,"abstract":"Transvalvular turbulence caused by the blood flow in implanted cardiac valvular prosthesis is the cause of thrombosis at the post-valvular region. The literature in this connection indicates that thromboembolic complications are more common with the tilting disc mechanical valves. In order to study the turbulence caused by porcine biological prosthetic valves, by a caged-ball Biomed mechanical valve and by a tilting disc Björk-Shiley valve, a device was developed which permits to visualize and to photograph flow characteristics in the three types of valves with the purpose of determining the degree of turbulence generated in each case. An additional accessory equipment was devised for the purpose of measuring static and dynamic pressures at various levels of the test tube containing the prosthetic valve wherein the variations in pressure reflect the degree of turbulence. The data obtained from 500 pressure registrations were analyzed in a computer. The data indicate that the porcine biological valve causes the least turbulence, whereas the mechanical valves create greater turbulence. Of the mechanical valves, the tilting disc prosthetic valve causes considerably greater turbulence, in particular in the vicinity of the smaller orifice.","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 2","pages":"145-53"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13258697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0