G MacGrogan, C Henriques, I De Mascarel, I Soubeyran, J Molimard, B Barreau, C Tunon De Lara, E Bussieres, M H Dilhuydy
{"title":"[Large core of nonpalpable breast lesions].","authors":"G MacGrogan, C Henriques, I De Mascarel, I Soubeyran, J Molimard, B Barreau, C Tunon De Lara, E Bussieres, M H Dilhuydy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The development of breast cancer screening has radically changed the diagnostic approach to breast lesions. Stereotactic large-core breast biopsy was developed to reduce the number of unnecessary surgical excisional biopsies in the increasing number of patients with doubtful or suspicious mammogram findings. The methods used to evaluate this new technique are discussed, as well as results in terms of efficacy, factors that may influence efficacy, and difficulties in interpreting large-core biopsies. Recommendations regarding the harvesting and interpretation of stereotactic large-core biopsies are made.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 4","pages":"241-6"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Borderline lesions of the thyroid: diagnostic strategy].","authors":"G Belleannée, H Trouette, A De Mascarel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Some thyroid neoplasms notoriously cause problems in the histologic diagnosis of their nature (follicular versus papillary for example) or their malignant potential (adenoma versus carcinoma) because of overlapping histologic features. Here, thyroid lesions are presented according to their histologic presentation (vesicular, papillary, trabecular, solid or cystic patterns, fibrosing thyroids and lymphoid infiltrate). For each entity, the most discriminant histologic features are described with emphasis on the diagnostic pitfalls and their histological clues.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 1-2","pages":"112-20"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Arrhythmogenic right ventricular dysplasia and cardiomyopathy. Clinical and anatomic-pathologic aspects, nosologic approach].","authors":"F Fontaliran, S Arkwright, F Vildé, G Fontaine","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Arrhythmogenic right ventricular dysplasia is a polymorphous clinical entity. Its diagnosis is difficult in incomplete forms or at the onset of the disease. The diagnosis is based on the association of clinical, electrocardiographic and electrophysiologic signs which are the result of a specific pathological structure, consisting of fibromuscular bundles isolated from each other by fatty tissue resulting from apoptosis and/or the basic dysplastic phenomenon. These fibers are oriented in a parallel direction and connected at their extremities with normal myocardium. These fibromyocyte bundles seem to constitute a tissue with preferential conduction, which could explain reentry phenomena, and therefore the basis for the pathogenesis of ventricular arrhythmias. The various clinical aspects of ARVD have similar morphological patterns, but a completely different prognosis and outcome.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 3","pages":"171-7"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Origin and progression of thyroid epithelial tumors: molecular and cellular mechanisms].","authors":"V Gire, D Wynford-Thomas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tumours of the thyroid follicular cell have been intensively studied as a model for investigating the molecular genetics of tumour development in epithelial cells. This review summarises the abnormalities of oncogenes and tumour suppressor genes which have been associated with the major sub-types of thyroid tumour. Although inevitably incomplete, the available data demonstrate well how successive genetic abnormalities drive clonal progression. Comparison of follicular and papillary tumours also reveals a fascinating correlation between genotype and pathological behaviour, consistent with a determining influence of the initiating oncogene on the \"route\" of tumour development. Finally, the emerging clinical implications are discussed.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 1-2","pages":"11-8"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Oxyphilic cell and clear cell carcinoma of the thyroid].","authors":"M L Houcke, M Patey","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Oxyphilic cell (Hürthle cell) carcinomas of the thyroid gland, variant of follicular carcinoma, are more malignant than follicular non oxyphilic cell carcinomas with a similar size and degree of invasiveness. Gross features, microscopic features of oxyphilic, clear and bicolored cells carcinomas and diagnostic techniques are related with a differential diagnosis with papillary oxyphilic cell carcinoma.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 1-2","pages":"79-85"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Thyroid papillary carcinoma and its variants].","authors":"N Berger, A Borda, M H Bizollon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors discuss the histological features of classical thyroid papillary carcinoma, with special emphasis on pathologic indicators related to prognosis. Its different variants are described, including: microcarcinoma, encapsulated variant, pure follicular variant, solid/trabecular variant, diffuse sclerosing and the cytologic variants of tall, columnar and oncocytic cell.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 1-2","pages":"45-61"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Franc, C Ledent, P P de Saint-Maur, M Parmentier
{"title":"[Thyroid insular carcinoma].","authors":"B Franc, C Ledent, P P de Saint-Maur, M Parmentier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This review article illustrates the several histological and immunohistochemical patterns of thyroid insular carcinoma and their associated disease. Differential diagnosis are also discussed. Poorly differentiated thyroid carcinomas are overviewed. The interest of transgenic mice models is presented.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 1-2","pages":"63-78"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Diagnostic difficulties and limits in imaging].","authors":"M Meunier, F Thibault","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fine-needle cytology and core biopsy of the breast done under mammographic or ultrasonographic guidance can assist in decision-making (monitoring, diagnostic or therapeutic procedures). Cytologic studies and histologic evaluation of core biopsies have their own limitations: the samples are small in size, and the histopathological features of the lesions are often complex. Each step of an image-guided diagnostic procedure contributes to the reliability of the method. The characteristics of the mammogram and/or ultrasonogram image provide initial orientation. Whether they are concordant with the results of the cytologic or histologic study is an important factor. The main limitations of stereotactically-guided biopsies are ballistic with targets that are difficult to circumscribe (fine microcalcifications or ill-defined density). With ultrasonography, verification of the sampling site in the target is essential. The performances of these procedures are closely dependent on the experience of the operators and on the quality of the cooperation between clinicians, radiologists and pathologists.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 4","pages":"247-50"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Mitochondrial DNA and Parkinson disease. Methodologic review].","authors":"V Pautot, C Macaigne, P Chariot","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Unlabelled: </strong>Parkinson's disease (PD), a disorder of unknown etiology, is associated with the degeneration of dopaminergic neurons in nigro-striatal pathways. MPTP, a meperidine analog, causes parkinsonism in human and nonhuman primates. MPP+, the active metabolite of MPTP, inhibits the activity of respiratory chain complex I. In patients with PD, a reduced complex I activity was found in substantia nigra, skeletal muscle, and platelets. Because complex I is partially encoded by the mitochondrial genome, several studies have searched for mitochondrial (mt) DNA abnormalities in patients with PD. Our aim was to answer the following questions: (1) are there some abnormalities of mtDNA in PD? (2) if there are some, what are these abnormalities? and (3) what is the pathogenic role of these abnormalities?</p><p><strong>Methods: </strong>The literature review was performed using Medline [National Library of Medicine, Washington] and Current Contents [Institute for Scientific Information, Philadelphia] databases. Periods screened were 1966-March, 1998 (Medline) and March 17, 1997-March 9, 1998 (Current Contents). Keywords were: \"Parkinson\" or \"Parkinson's\", and \"mitochondrial DNA\" or \"mtDNA\". We limited our research to articles in English and French.</p><p><strong>Results: </strong>Medline search provided 59 articles. Current Contents search provided 22 articles. Twelve articles were found in both databases. Thirty-eight of the 69 articles were either reviews about mitochondrial diseases (19 articles) or original articles not related to mtDNA (19 articles). Our final selection included the remaining 31 articles.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 4","pages":"261-8"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary lymphomas of the thyroid gland: a review with emphasis on diagnostic features.","authors":"E Fonseca, C Sambade","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The information about primary lymphomas of the thyroid--a rare form of thyroid tumor and a rare form of lymphoma as well--is dispersed in numerous scientific publications. Recent developments in the field of lymphoid neoplasias, in particular the recognition of mucosa-associated lymphoid tissue (MALT) and the characterization of its distinctive type of lymphomas, has drawn new attention to primary lymphomas of the thyroid and has provided new insights into this field of thyroid pathology. In this paper we review the pathogenesis and the clinicopathologic features of primary lymphomas of the thyroid, we discuss the diagnostic basis and the strategies for differential diagnosis, and we address some recent data that may provide additional pathways to further our understanding of those rare thyroid diseases.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"46 1-2","pages":"94-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20667912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}