{"title":"[Extramembranous glomerulonephritis: clinicopathologic finding in a group of 45 Cameroonians].","authors":"T J Youmbissi, A Mbakop, Eloundou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Forty five Cameroonian patients in West Africa who were diagnosed as having membranous glomerulonephritis (MGN) were studied and followed up over a five year period. The mean age of these patients was 32.3 years with a female to male ratio of 5/4. Proteinuria (93.3%) and nephrotic syndrome (89%) were the two most important clinical manifestations at the time of diagnosis. Seventeen cases (37.8%) of the MGN were considered idiopathic while 62.2% were associated with known aetiological factors. Histologically, the majority of patients were at stage I (35.55%) or stage II (37.8%) of the World Health Organisation (WHO) classification. Except of the patients in stage I, most patients in stage II and all those in stages III and IV, showed associated important, tubular interstitial and vascular lesions. Immunofluorescence studies showed deposits to be mainly IgG (80%) and C3 (71.1%) while electron microscopy showed varied dense deposits in all cases. Seventeen patients with idiopathic MGN and 10 MGN patients whose only associates aetiological factor was a positive hepatis B antigen were followed up over 5 years. During this period, eight patients (29.6%) had a complete clinical remission, eleven patients (40.7%) improved their renal function and decreased their 24 hour proteinuria, while eight (29.6%) patients deteriorated into end stage renal failure and had to be commenced on dialysis; three of them died during this procedure.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"48-52"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Granular cell tumor. Epidemiology of 263 cases].","authors":"V Billeret Lebranchu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>263 cases of granular cell tumour had collected [thanks to the collaboration of pathologists Septentrional Association of North, Pas-de-Calais and Aisne departments (A.S.A.P.)]. We studied the age, sex, localisations and the particularity of these tumours. These results had compared to other large series of the literature. Our study showed a majority of men (68%), twenty to sixty year old. The preferential sites are skin (38.57%), oesophagus (19.64%) and tongue (10%). The granular cell tumour is multiple in fifteen cases and associated to neoplastic tumour in twelve cases. Only one case recurred after incomplete excision. There were none malignant tumour.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V Billeret-Lebranchu, E Martin de la Salle, B Vandenhaute, M Lecomte-Houcke
{"title":"[Granular cell tumor and congenital epulis. Histochemical and immunohistochemical of 58 cases].","authors":"V Billeret-Lebranchu, E Martin de la Salle, B Vandenhaute, M Lecomte-Houcke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>56 cases of granular cell tumour and 2 cases of granular cell congenital epulis have been studied morphologically, histochemically and immunohistochemically. The subject of this study is to evaluate the diagnosis interest of the PAS stain, determine the positivity of 4 antibodies (vimentin, NSE, PS100, NK1/C3) and confirm or not the neuroectodermic origin. The study showed that the microscopic findings are often sufficient. When the diagnosis is less evident, the PAS stain is not discriminant, but we can use the immunohistochemistry study: we confirmed the positivity of the 4 antibodies, but PS100 and NK1/C3 are the most constant. Only the 2 cases of granular cell congenital epulis always show negative immunoreactivity with S100 protein. About the histogenesis, our study confirm the neurogenic origin, but the hypothesis of a non neoplastic nature is raised.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"31-7"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Papillary fibroelastoma: a cardiac tumor rarely reported in children].","authors":"B B Hami, F Le Gall, H Jouan, C Almange, R Loire","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Papillary fibroelastoma is a seldom reported tumour. It usually occurs in adults and develops on the aortic and mitral valves. It is not different of giant Lambl excrescences and differential diagnostic can be difficult with the myxoma. Its systematic surgical ablation is justified by the important risk of embolic complications. It has rarely been reported in children. We report a case peculiar by fortuitous diagnostic, tricuspid site, large size and occurrence in a 3-year old child.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"53-6"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Gamoudi, F Bougrine, G Jerbi, M Hechiche, R Khattech, H Boussen, K Rahal, K Ben Romdhane
{"title":"[Peritoneal pseudomyxoma associated with an ovarian and appendicular mucinous tumor].","authors":"A Gamoudi, F Bougrine, G Jerbi, M Hechiche, R Khattech, H Boussen, K Rahal, K Ben Romdhane","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors report a case of pseudomyxoma peritonei associated with an appendicular and ovarian mucinous tumor. They emphasize the rarity of bilateral ovarian and appendicular involvement and they discuss the problem of the origin of the primary tumor and evaluation of the prognosis.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"57-60"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Mezlini, N Kchir, M Chaabouni, A Ben Rejeb, F Ben Ayed
{"title":"[Primary gastric MALT lymphoma in children. Report of 2 cases].","authors":"A Mezlini, N Kchir, M Chaabouni, A Ben Rejeb, F Ben Ayed","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Primary gastric MALT non-Hodgkin's lymphoma is rare in immunocompetent children. To our knowledge, only two cases have been previously described. We report two cases of gastric MALT lymphoma associated with Helicobacter pylori. Clinico-pathological features are similar to those observed in adults. The relationship between the microbial infection and non-Hodgkin's lymphoma development is discussed.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"38-43"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Biotin-rich pseudoherpetic intranuclear inclusions. A diagnostic pitfall].","authors":"E Leteurtre, F Boman, B Gosselin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Biotin-rich pseudoherpetic nuclear inclusions may be observed in endometrial epithelial cells during pregnancy, post-partum or in association with choriocarcinoma. They may be observed in tumor cells in a few papillary carcinomas of the thyroid gland in young women. These inclusions may be responsible for false diagnoses of herpesvirus infection at morphological and immunocytochemical examination. They may be responsible for false positives in immunocytochemistry and in situ hybridization.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"44-7"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bone giant cell tumour in neuropathological practice. A fifty year overview.","authors":"M Kujas, T Faillot, R Van Effenterre, J Poirier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report a case of a 29-year-old female patient who suffered from visual disturbance, resulting from a lesion in the sphenoid bone which, histologically, proved to be a giant cell tumour. Reviewing our laboratory practice over a 50 year period, only 7 cases of true giant cell tumour were found and they were in two major locations, i.e. the skull and vertebrae. These few cases led us to focus on the problem raised by the lack of histological patterns of malignancy. In agreement with Mazabraud's theory, it seems that a vertebral location is associated with a good prognosis and that gene mapping of chromosome 17 in relation to p53 mutations could be a valuable tool in the diagnosis of potential malignant behaviour.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Loire, A V Donsbeck, N Nighoghossian, M Perinetti, F Le Gall
{"title":"[Papillary fibroelastoma of the heart. A review of 20 cases].","authors":"R Loire, A V Donsbeck, N Nighoghossian, M Perinetti, F Le Gall","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After a period during which cardiac papillary fibroelastomas were considered incidental autopsy findings cerebral and coronary arteries embolism proved their aggressiveness. Echocardiography is now able to identify them and surgical resection is rapidly required. Sea anemone like macroscopic pattern is characteristic with finely villous masses, each frond being at microscopical examination formed by a central fibroelastic core surrounded by a myxomatous layer overlied by endothelial cells. Histogenesis remains elusive and we tried to clarify it by immunohistochemical analysis of 8 of the 20 cases studied (10 autopsies, 10 surgical resections). Morphological and immunohistochemical data show that endothelial cells play the most important part in abnormal formations.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Central neurocytoma. Immunohistochemical study: MIB1, p53 and bcl-2. Report of 5 cases].","authors":"E Uro-Coste, P Bousquet, P Arrue, M B Delisle","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To further characterize central neurocytoma, a rare intraventricular tumour described in 1982, we analyzed six tumours by immunohistochemistry for MIB1, p53 and bcl-2. bcl-2, an inhibitor of p53-mediated apoptosis is frequently expressed in gliomas, especially in tumors with wild-type p53. Its expression in peripheral neuroblastomas suggests a down-regulation during final terminal differentiation. Six tumors from five patients (one female/four males, age ranged from 18 to 63 years) were examined. All patients were alive from 2 to 88 months after initial surgical resection. On histological sections, tumours demonstrated a typical pattern. Synaptophysin staining was seen in all cases. Proliferation index was low (< 4.5%). bcl-2 was never expressed. p53 expression varied but within low values (< 10% of cells). These latter antibodies were rarely analyzed until now in this usually benign neoplasm which represents a well differentiated variant of neuron derived tumors.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"47 1","pages":"13-8"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20962927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}