African journal of reproductive health最新文献_第9页

Perioperative dynamics of siglec-15 and soluble PD-L1 in ovarian cancer surgery: Influence of anaesthetic technique on immune regulation. 卵巢癌手术围术期sigle -15和可溶性PD-L1的动态变化：麻醉技术对免疫调节的影响

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-07-15 DOI: 10.29063/ajrh2026/v30i13.7

Cui Zhao, Linqian Zhang, Meng Wang, Yangtao Gao, Mingjie Chen, Long Qi, Jiayi Fu, Yingui Sun, Shuo Feng

{"title":"Perioperative dynamics of siglec-15 and soluble PD-L1 in ovarian cancer surgery: Influence of anaesthetic technique on immune regulation.","authors":"Cui Zhao, Linqian Zhang, Meng Wang, Yangtao Gao, Mingjie Chen, Long Qi, Jiayi Fu, Yingui Sun, Shuo Feng","doi":"10.29063/ajrh2026/v30i13.7","DOIUrl":"10.29063/ajrh2026/v30i13.7","url":null,"abstract":"This prospective observational study investigated the perioperative dynamics of circulating sialic acid-binding immunoglobulin-like lectin 15 (SIGLEC-15) and soluble programmed death-ligand 1 (sPD-L1) in patients with ovarian cancer undergoing surgery with either total intravenous anesthesia or inhalational anesthesia. Patients were consecutively enrolled, and peripheral blood samples were collected at predefined perioperative time points. Biomarker levels were measured and compared between anesthesia groups, and their associations with immune and inflammatory parameters were analyzed using appropriate statistical methods. Following surgery, levels of SIGLEC-15 and soluble programmed death-ligand 1 increased significantly, peaking at 24 hours and remaining elevated at 72 hours, with more pronounced changes observed in the inhalational anesthesia group. Elevated biomarker levels were associated with greater immune dysregulation, reflected by alterations in natural killer cell proportion, CD4 to CD8 T-cell ratios, and increased levels of interleukin-6 and cortisol. These findings suggest that SIGLEC-15 and soluble programmed death-ligand 1 may serve as blood-based indicators of perioperative immune status. However, their long-term clinical significance requires further investigation. Overall, this study underscores the importance of dynamic monitoring of immune biomarkers during the surgical period to better understand their role in ovarian cancer management.","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":" 13","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148443916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of tourniquet with and without adjunctive misoprostol on haemorrhage during open myomectomy: A randomised controlled trial. 带米索前列醇和不带米索前列醇的止血带治疗开放性子宫肌瘤切除术出血的有效性：一项随机对照试验。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-07-15 DOI: 10.29063/ajrh2026/v30i13.4

Rally O Edema, Patrick Okonta, Ayotunde Adeyinka, Amos Ekoh, V Lloyd Jagu

{"title":"Effectiveness of tourniquet with and without adjunctive misoprostol on haemorrhage during open myomectomy: A randomised controlled trial.","authors":"Rally O Edema, Patrick Okonta, Ayotunde Adeyinka, Amos Ekoh, V Lloyd Jagu","doi":"10.29063/ajrh2026/v30i13.4","DOIUrl":"10.29063/ajrh2026/v30i13.4","url":null,"abstract":"Reducing intraoperative haemorrhage during open abdominal myomectomy is essential, as excessive bleeding is a major complication. This double-blind, randomised controlled trial, conducted at two tertiary hospitals in Nigeria between July 2020 and January 2021, compared the effect of combining misoprostol with a tourniquet versus a tourniquet alone on intraoperative blood loss. One hundred and forty consenting women were randomised in equal numbers to the intervention (tourniquet plus misoprostol) or the control (tourniquet only) group. The primary outcome was intraoperative blood loss, while secondary outcomes included duration of surgery, blood transfusion requirements, and adverse effects. Mean blood loss was significantly lower in the intervention group (678.2±42.4 ml) than in the control group (837.0±39.2 ml; P=0.042). There were no significant differences in transfusion rates, operative duration, or side effects between groups. The addition of misoprostol to a pericervical tourniquet effectively reduces intraoperative blood loss without increasing adverse events in women undergoing open abdominal myomectomy.","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":" 13","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148443914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of pregnant women's awareness and practice of antenatal care in Mosul, Iraq. 对伊拉克摩苏尔孕妇产前护理意识和实践的评估。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-06-26 DOI: 10.29063/ajrh2026/v30i12.6

Nadia H Saied, Esraa M Z Shihab, Najlaa S Sheet

引用次数: 0

Investigating the individual and contextual factors associated with non-use of newborn postnatal care in Eswatini. 调查与斯瓦蒂尼未使用新生儿产后护理相关的个人和环境因素。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-06-26 DOI: 10.29063/ajrh2026/v30i12.2

Boipelo A Tlalang, Lungisile Shange, Mluleki Tsawe

引用次数: 0

Financial and legal empowerment in women's reproductive health decision-making in rural China and Pakistan: A qualitative study. 中国和巴基斯坦农村妇女生殖健康决策中的财政和法律赋权：一项定性研究。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-06-26 DOI: 10.29063/ajrh2026/v30i12.9

Zhang Biao, Sun Zhongfeng, Muhammad S Khan

{"title":"Financial and legal empowerment in women's reproductive health decision-making in rural China and Pakistan: A qualitative study.","authors":"Zhang Biao, Sun Zhongfeng, Muhammad S Khan","doi":"10.29063/ajrh2026/v30i12.9","DOIUrl":"https://doi.org/10.29063/ajrh2026/v30i12.9","url":null,"abstract":"This study investigates how financial and legal empowerment affects women's reproductive health decisions in rural China and Pakistan, both of which face notable patriarchal and socioeconomic challenges. We used a qualitative approach, employing semi-structured interviews to gather in-depth insights from rural women who faced barriers in making reproductive health decisions due to financial and legal constraints. We used purposive sampling to recruit participants. Data were collected from 30 women aged 18-45 years from rural Anhui Province, China, and Khyber Pakhtunkhwa, Pakistan. The results show that women are much better able to make informed choices about their reproductive health when they are financially independent, have control over their money and income opportunities, and are aware of their legal rights. Women who are economically empowered and legally informed have greater autonomy in accessing reproductive healthcare and challenging patriarchal norms. The study concludes that financial and legal empowerment are essential for enhancing reproductive health outcomes and that their integration into policy and practice is crucial for enabling women's independent reproductive decisions. This study contributes to the literature on women's autonomy in reproductive health by highlighting the combined role of financial and legal empowerment, offering insights for policymakers, healthcare providers, and legal reformers seeking to improve reproductive health outcomes in rural marginalized communities.","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":"30 12","pages":"81-94"},"PeriodicalIF":1.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strengthening data systems to advance sexual and reproductive health and rights in sub-Saharan Africa. 加强数据系统，以促进撒哈拉以南非洲的性健康和生殖健康及权利。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-06-26 DOI: 10.29063/ajrh2026/v30i12.1

Lorretta Favour Chizomam Ntoimo, Friday Okonofua

引用次数: 0

Mobile phone accessibility, health information needs, and willingness to receive maternal health information via mobile applications among pregnant women attending antenatal care in Oshana Region, Namibia. 纳米比亚奥沙纳地区参加产前保健的孕妇的移动电话可及性、保健信息需求以及通过移动应用程序接收孕产妇保健信息的意愿。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-06-26 DOI: 10.29063/ajrh2026/v30i12.8

Ester Mulenga, Hedvig Nk Mendonca, Shange T Ndakunda, Ndapunikwa Uukule, Petrus K Shingandji, Natalia T Ndjuluwa, Beatrix N Ndahalele, Yoseph Worku

{"title":"Mobile phone accessibility, health information needs, and willingness to receive maternal health information via mobile applications among pregnant women attending antenatal care in Oshana Region, Namibia.","authors":"Ester Mulenga, Hedvig Nk Mendonca, Shange T Ndakunda, Ndapunikwa Uukule, Petrus K Shingandji, Natalia T Ndjuluwa, Beatrix N Ndahalele, Yoseph Worku","doi":"10.29063/ajrh2026/v30i12.8","DOIUrl":"https://doi.org/10.29063/ajrh2026/v30i12.8","url":null,"abstract":"Mobile technologies have proven to be effective in disseminating health information and improving health outcomes. This study assessed mobile phone accessibility, health information needs and the willingness to receive health information via mobile application among pregnant women attending antenatal care in the Oshana Region, Namibia. A cross-sectional study was conducted among 337 pregnant women. Statistical significance was set at p < 0.05. Most of the participants (91.7%) reported having access to mobile phones. The top five maternal health information needs identified were: activities during pregnancy, antenatal care visits, emergency preparedness, breastfeeding, and nutrition during pregnancy. Notably, 97.5% of the participants expressed willingness to receive health information via mobile applications. Mobile phone ownership was significantly associated with the willingness to receive health information through mobile applications (p = 0.022). Given the high level of mobile access among pregnant women in Namibia, there is a need to develop and disseminate health information via mobile application platforms.","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":"30 12","pages":"73-80"},"PeriodicalIF":1.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of simulation-based continuing education in neonatal resuscitation among Moroccan midwives: A quasi-experimental study. 基于模拟的继续教育在摩洛哥助产士新生儿复苏中的有效性：一项准实验研究。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-06-26 DOI: 10.29063/ajrh2026/v30i12.3

Sara Alaoui, Kamal Takhdat, Widad Lahmini, Saloua Lamtali, Mohamed Loukid

{"title":"Effectiveness of simulation-based continuing education in neonatal resuscitation among Moroccan midwives: A quasi-experimental study.","authors":"Sara Alaoui, Kamal Takhdat, Widad Lahmini, Saloua Lamtali, Mohamed Loukid","doi":"10.29063/ajrh2026/v30i12.3","DOIUrl":"10.29063/ajrh2026/v30i12.3","url":null,"abstract":"Neonatal mortality remains a critical public health issue, particularly in resource-limited settings. Simulation-based programs such as Helping Babies Breathe (HBB) have proven effective in strengthening midwives' knowledge and skills in neonatal resuscitation, yet no study has evaluated their impact among practicing Moroccan midwives. The objective of this study was to assess the effectiveness of HBB training on satisfaction, self-efficacy, theoretical knowledge, one-year knowledge retention, and technical skills among practicing Moroccan midwives. A quasi-experimental pre-post study was conducted with 96 midwives. The intervention included a didactic session, hands-on practice, and formative simulation. Satisfaction, self-efficacy, and knowledge were measured through questionnaires; technical skills were evaluated using OSCE checklists for the Golden Minute and positive pressure ventilation. Satisfaction was 100%, and full self-efficacy increased markedly post-training. Knowledge improved significantly and remained stable at follow-up. Technical skills showed high scores with minimal failure rates. Knowledge moderately correlated with ventilation performance. In conclusion, HBB simulation-based training significantly enhances and sustains neonatal resuscitation competencies among Moroccan midwives, supporting its systematic integration into continuous professional development.","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":"30 12","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148325319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal health literacy programmes to improve self-care of pregnant women in Africa: A scoping review. 改善非洲孕妇自我保健的孕产妇保健扫盲方案：范围审查。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-06-26 DOI: 10.29063/ajrh2026/v30i12.12

Thabani M Noncungu, Thandi Sibindi, Jennifer Chipps, Talitha Crowley

{"title":"Maternal health literacy programmes to improve self-care of pregnant women in Africa: A scoping review.","authors":"Thabani M Noncungu, Thandi Sibindi, Jennifer Chipps, Talitha Crowley","doi":"10.29063/ajrh2026/v30i12.12","DOIUrl":"https://doi.org/10.29063/ajrh2026/v30i12.12","url":null,"abstract":"Midwives are uniquely positioned to implement health literacy programmes, yet there is limited synthesis of existing midwife-led health literacy programmes for pregnant women in Africa. This scoping review maps the evidence on health literacy programmes to improve the self-care of pregnant women in Africa. Eight articles, published between 2015 and 2025, were included across African countries from six electronic databases, such as MEDLINE and one search engine: Google Scholar. Maternal health literacy programmes varied in mode of delivery, duration, components, and outcomes. Most programmes used a group antenatal care model, a combination of face-to-face and digital health tools, and focused on improving functional, interactive, and critical health literacy. Maternal health literacy programmes in African countries seem to be under-researched. More research is needed to strengthen the outcomes of programmes such as usability and acceptability, knowledge and awareness, and clinical outcomes. In addition, longer-term research is necessary to assess the implementation and sustained impact of these programmes.","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":"30 12","pages":"115-135"},"PeriodicalIF":1.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review of unintended pregnancy among adolescents living with HIV in Africa. 非洲感染艾滋病毒的青少年意外怀孕的系统回顾。

IF 1 4区医学

African journal of reproductive health Pub Date : 2026-06-26 DOI: 10.29063/ajrh2026/v30i12.11

Mackline Hope, Fahad Lwigale, Conrad Tumwine, Reuben Kiggundu, Herman Mwanja, Edmund Nartey

{"title":"A systematic review of unintended pregnancy among adolescents living with HIV in Africa.","authors":"Mackline Hope, Fahad Lwigale, Conrad Tumwine, Reuben Kiggundu, Herman Mwanja, Edmund Nartey","doi":"10.29063/ajrh2026/v30i12.11","DOIUrl":"https://doi.org/10.29063/ajrh2026/v30i12.11","url":null,"abstract":"Adolescent pregnancy remains a significant public health concern across Africa, with Eastern and Southern regions experiencing the highest burden. Among adolescents living with HIV(ALHIV), the challenge is intensified by socio-economic, cultural, and healthcare factors that increase vulnerability to unintended pregnancy. This systematic review examined the prevalence of unplanned pregnancy and associated factors among adolescents living with HIV in Africa. Following PRISMA guidelines and registered in PROSPERO (CRD42024564479), a search of Medline, EMBASE, and CINAHL identified relevant studies published between 2011 and 2023. Of the 550 retrieved articles, only three met the inclusion criteria. Reported prevalence rates varied widely, ranging from 18.8% in South Africa to 60.0% and 73.9% in Kenya, indicating a substantial and uneven burden across settings. Factors associated with unintended pregnancy included involvement with boyfriends or acquaintances rather than spouses, reflecting limited agency and structural vulnerabilities. Documented adverse outcomes included miscarriage, stillbirth, and abortion, although one study did not specify outcomes. Overall, the review highlights persistently high rates of unplanned pregnancy among adolescents living with HIV and underscores the need to integrate sexual and reproductive health services into HIV care, address stigma, and strengthen context-specific interventions.","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":"30 12","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0