Clinical application of vaginal natural orifice transluminal endoscopic surgery in hysterectomy.

This study aimed to evaluate the effect of vaginal natural orifice transluminal endoscopic surgery in hysterectomy. A retrospective analysis of 80 patients who underwent hysterectomy at the Maternity & Child Care Center in Qinhuangdao, China from October 2022 to October 2024 was conducted. The patients were randomly divided into a transumbilical laparoendoscopic single-site surgery group and a vaginal natural orifice transluminal endoscopic surgery group. The surgical time of 40 cases of the vaginal natural orifice transluminal endoscopic surgery group tended to stabilize, and learning curve showed no marked fluctuations. The anal exhaust time, indwelling catheter time, hospital stay, and degree of pain in vaginal natural orifice transluminal endoscopic surgery group were less than the transumbilical laparoendoscopic single-site surgery group. On the first day after surgery, compared to the transumbilical laparoendoscopic single-site surgery group, the vaginal natural orifice transluminal endoscopic surgery group had higher superoxide dismutase and glutathione peroxidase levels and lower malondialdehyde and advanced oxidation protein products levels. We conclude that vaginal natural orifice transluminal endoscopic surgery has less postoperative pain than transumbilical laparoendoscopic single-site surgery, which reduces patients' postoperative stress responses and facilitates postoperative recovery.