Annales d'immunologie最新文献_第3页

[Characterization of the antigen in circulating immune complexes and application to the detection of streptococcal antigens in human infectious endocarditis]. [循环免疫复合物中抗原的表征及其在人感染性心内膜炎链球菌抗原检测中的应用]。

Annales d'immunologie Pub Date : 1983-03-01

L Grangeot-Keros, L Lebrun, S Badur, E Sacquet, J Pillot

引用次数: 0

[Selective binding in vitro of a modified form of the C3 component of complement to human erythrocytes]. [补体C3成分修饰形式与人红细胞的体外选择性结合]。

Annales d'immunologie Pub Date : 1983-03-01

C Micouin, E Hudry-Clergeon, B Roussel, N Battail, A Tournoud, M G Colomb

{"title":"[Selective binding in vitro of a modified form of the C3 component of complement to human erythrocytes].","authors":"C Micouin, E Hudry-Clergeon, B Roussel, N Battail, A Tournoud, M G Colomb","doi":"","DOIUrl":"","url":null,"abstract":"C3 was bound to human erythrocytes from autologous plasma or from serum brought to low ionic strength (mu less than or equal to 0.03) and pH between 4.0 and 5.0, then subsequently incubated with erythrocytes (50/1, v/v) for 20 min at 0 degree C. This capacity was preserved up to 72 h by prolonged incubation at 20, 25 or 37 degrees C, whereas it was quickly lost by incubation at 0 degree C. C3 binding did not require complement activation and was not observed with neuraminidase-treated erythrocytes. Crossed immunoelectrophoretic analysis of the pretreated serum or plasma revealed that a fraction having more cathodal migration than that of native C3 was generated upon incubation in the above-mentioned conditions. This fraction appeared able to selectively bind to the erythrocytes. Cell-bound C3 reacted positively to antisera against C3a, C3c, C3d or native C3; they rosetted positively with EAC3b, clearly showing that this C3 binding was not dependent on the proteolysis of C3 and that it concerned the acceptor sites on the cells, since C3b receptors were free. The functional significance of this C3 binding was also investigated: EC3 were not able to lyse through the alternative pathway, whereas lysis clearly increased when C3 was found to AET-treated erythrocytes. This finding, together with the modulation in the capacity of EC3 or E(AET)C3 to form an alternative pathway convertase by antibodies to C3c or C3d, strongly suggests a contribution of bound C3 to such a convertase. In contrast to \"C3b-like\" C3, this modified C3 was able to bind to acceptor sites on erythrocytes but, like the former, it retained the capacity to form an alternative pathway convertase. In this light, it may represent an intermediate between C3 and \"C3b-like\" C3.","PeriodicalId":75508,"journal":{"name":"Annales d'immunologie","volume":"134C 2","pages":"237-53"},"PeriodicalIF":0.0,"publicationDate":"1983-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17287362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Inflammation and antibacterial resistance. III. Influence of an inflammatory reaction induced by the injection of polyacrylamide gels on the resistance of mice to Listeria monocytogenes infection]. [炎症和抗菌抗性。]3注射聚丙烯酰胺凝胶诱导的炎症反应对小鼠单核增生李斯特菌感染抗性的影响[j]。

Annales d'immunologie Pub Date : 1983-03-01

E Fontan, R M Fauve

引用次数: 0

[Comparative kinetics of spleen cell-mediated antibody-dependent cytotoxic activity in mice treated with BCG or Mycobacterium smegmatis]. [卡介苗或耻垢分枝杆菌处理小鼠脾细胞介导的抗体依赖性细胞毒活性的比较动力学]。

Annales d'immunologie Pub Date : 1983-03-01

F Hérodin, D Dormont

引用次数: 0

[Genetic organization and polymorphism of the HLA-D region]. HLA-D区域的遗传组织和多态性。

Annales d'immunologie Pub Date : 1983-01-01

L Guilherme, M Colombani, N Sansonetti, J Colombani

引用次数: 0

[Presence of 2 different epitopes on the human beta 2-microglobulin defined by monoclonal antibodies]. [单克隆抗体定义的人β 2微球蛋白上存在2个不同的表位]。

Annales d'immunologie Pub Date : 1983-01-01

D Crevat, J Kalil, F Rosa, M Fellous

引用次数: 0

[Immunofixation in agarose gel for the identification of monoclonal immunoglobulins]. 【琼脂糖凝胶免疫固定法鉴定单克隆免疫球蛋白】。

Annales d'immunologie Pub Date : 1983-01-01

F Potdevin, M Roncato, F Drupt, M Paris, M Leclerc

引用次数: 0

[Alpha 1-antitrypsin/lymphocyte interactions: cytofluorometry study]. [α 1-抗胰蛋白酶/淋巴细胞相互作用:细胞荧光法研究]。

Annales d'immunologie Pub Date : 1982-11-01

J Bata, G Cordier

引用次数: 0

Influence of malaria on a pre-existing antibody response to heterologous antigens. 疟疾对预先存在的抗体对异源抗原反应的影响。

Annales d'immunologie Pub Date : 1982-11-01

P Goumard, N Vu Dac, P Maurois, D Camus

{"title":"Influence of malaria on a pre-existing antibody response to heterologous antigens.","authors":"P Goumard, N Vu Dac, P Maurois, D Camus","doi":"","DOIUrl":"","url":null,"abstract":"Swiss mice were immunized with various antigens: polyvinylpyrrolidone (PVP), human serum transferrin (HST), bovine serum albumin (BSA) or tetanus toxoid (TT). Fifteen days after the last injection of antigen, the mice were infected with Plasmodium chabaudi AJ. Two weeks after the beginning of malarial infection, parasitaemia became latent and total gammaglobulin levels, as well as IgG and IgM levels, were significantly increased. At that period the antigen-binding capacity (ABC) and the total antigen-binding Sites (Abt) were determined for PVP, HST and BSA. It appeared that the ABC and Abt of anti-HST or anti-BSA antibodies were lower than those of corresponding uninfected controls. With regard to anti-PVP antibodies, only the Abt was modified after infection, but not the ABC. The evolution of anti-TT Ab levels determined by a solid-phase assay with 125I-TT was as above with a marked decrease on and after the 4th week of infection. Injection of low-density lipoproteins (LDL) from day-9-infected mice to TT-immunized mice significantly reduced anti-TT antibody levels. At similar doses, LDL from normal mice did not induce an inhibitory effect. At mouse-equivalent-dose, LDL from infected mice revealed an inhibitory effect compared to LDL from uninfected controls. Our results suggest that LDL from P. chabaudi-infected mice can exert an immunoregulatory role and thus could explain part of the immune impairment observed during the infective process. Moreover, from the present data it might be postulated that the hypergammaglobulinaemia of P. chabaudi infection does not result from a parasite-potentiating effect on a pre-existing antibody response.","PeriodicalId":75508,"journal":{"name":"Annales d'immunologie","volume":"133D 3","pages":"313-26"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18180538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunoglobulin levels in seminal plasma of oligospermic patients. 少精症患者精浆免疫球蛋白水平。

Annales d'immunologie Pub Date : 1982-11-01

G M Prelević, M I Vircburger, M Vukotić, K Cuperlović, V Milović, M Petrović

引用次数: 0