{"title":"[Electronic microscopic study of a sacral chordoma. Characterization of various development stages of the tumor cells].","authors":"J P Thiery, A Mazabraud, J Mignot, M Durigon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The electron microscopic study of a sacral chordoma, the cells of which contain variable amounts of glycogen, allowed to characterize different stages in the evolution of the tumoral cells. The young cells contain almost no glycogen ; progressively it becomes more abundant and fills up almost the whole cytoplasm. At the end of the evolution glycogen disappears while the cell becomes vacuolated. This suggests that enzymatic lysis of this polysaccharide could be the cause of the vacuolation which finally produces the physaliferous cell. Comparison between the cells of the chordoma and those of the normal notochord shows some morphological similarities in the development of these cells. These different data may be useful for a classification of the various types of chordomas.</p>","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 2","pages":"193-204"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11801234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C S Papadimitriou, H K Müller-Hermelink, K Lennert
{"title":"Immune histochemical and electron microscopic observations on so-called non-specific mesenterial lymphadenitis.","authors":"C S Papadimitriou, H K Müller-Hermelink, K Lennert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two cases of so-called mesenterial lymphadenitis in childhood were investigated with the immunoperoxidase technique. One more case was studied electron microscopically. All three cases were morphologically identical. In two cases infection with Yersinia enterocolitica was proven serologically. The majority of the lymphoid cells which filled the strongly distended sinuses represented electron microscopically various steps of the lymphocyte transformation. Immune histochemically, the blasts contained large amounts of immunoglobulins. It is suggested that the mitogen and adjuvant activity of bacterial lipopolysaccharides may substantially be involved in the pathogenesis of the characteristic lesion of the mesenterial lymphadenitis.</p>","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 4","pages":"315-22"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11520958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Eosinophilic granulomatous hepatitis. Apropos of a case of toxocariasis].","authors":"W Bogomoletz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author reports an anatomoclinical observation of eosinophilic granulomatous hepatitis due to toxocariasis. The problems of the histologic differential diagnosis are discussed. Human cases of parasitic infestation by Toxacara canis--larva migrans syndrome--are quite uncommon (1, 2). In the acute stage the hepatic lesion most often consists in eosinophilic granulomatous hepatitis. The chance finding of an eosinophilic granuloma in a puncture biopsy of the liver may rise problems as concerns the histological differential diagnosis, especially when there is no clinical evidence of a parasitosis and when no parasite is found in the biospy specimen.</p>","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 1","pages":"75-9"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12064652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Tommasi, A Jouvet-Telinge, N Kopp, J Pialat, J Gilly
{"title":"[Alpers' infantile cerebral poliodystrophy. A case with abnormal hepatic pyruvate carboxylase].","authors":"M Tommasi, A Jouvet-Telinge, N Kopp, J Pialat, J Gilly","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors describe an anatomical familial case of progressive infantile cerebral poliodystrophy (Alpers disease), in which the study of enzyme kinetics of hepatic pyruvate carboxylase revealed an abnormal graph reflecting a loss of activity of the enzyme with low concentrations of substrate, This is a new feature in the literature on Alpers disease, and possibly indicates one of the pathogenic mechanisms responsible in this disorder which remains mysterious, although its pathology has been clearly described.</p>","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 4","pages":"337-42"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11820089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Micro-angiopathy and the dermal connective tissue in obesity].","authors":"H Bouissou, M T Pieraggi, M Julian, R Flores","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 2","pages":"117-32"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11801228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Balouet, M Baret, E Relyveld, P Ravisse, J Levaditi
{"title":"[Role of antigens and adjuvant substances in the histological response in experimental granulomas (immunogenic granuloma)].","authors":"G Balouet, M Baret, E Relyveld, P Ravisse, J Levaditi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The injection in rabbits of vaccinal antigens combined with immunity adjuvants (in particular calcium phosphate) causes a local lesion in which it is possible to recognize histologically, after a transitory afflux of polymorphonuclear leukocytes, a central area of adjuvant deposit, a middle area of histiocytes and monocytes, and a peripheral immunogenic area of lymphocytes and plasmocytes. These two cellular zones are rich in highly fluorescent cells in the presence of an antiglobulin serum with an embedding technique which respects to the upmost the structures and immunoreactivity of the cells. These histological features are not completely observed on the separate injection of antigen or adjuvant. They must be interpreted, after a fleeting non-specific reaction, while taking into account the still poorly understood method of action of the inorganic adjuvant and spread of the antigen in the organism.</p>","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 2","pages":"159-70"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11801231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hodgkin's disease with epithelioid cells. Study of 56 cases having undergone an exploratory laparotomy].","authors":"J Diebold, F Capron, L Temmim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Histological examination of the various specimens taken during an exploratory laparotomy for Hodgkin's disease revealed the presence of epithelioid cells in 56 cases out of a total of 235 patients (i.e. 23.8 p. 100). These cells were disseminated throughout the lymphoid tissue or grouped in clumps, in plaques or, more rarely, as true follicles. They were found either in contact with Hodgkin's lesions or at a distance in organs free of disease. They were found in Lukes-Rye histological types 1, 2 and, above all, 3. Their significance remains unknown. The most likely hypotheses would appear to be those of a response to the accumulation of substances to be eliminated (tumour antigens?) or those of a disorder in cellular immunity.</p>","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 3","pages":"221-32"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11817549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J F Heron, B Borel, J Beguin, J C Mandard, P Rousselot
{"title":"[Bone biopsy of the iliac crest. Technics of embedding in methacrylate and quantitative readings. Results of 2 years' experience].","authors":"J F Heron, B Borel, J Beguin, J C Mandard, P Rousselot","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors report their experience with a method for the study of undecalcified bone embedded in a compound of methacrylate allowing various types of staining procedures. They review the methods of semi-quantitative study of the bone activity and point out their interest in diffuse involvement of the skeleton.</p>","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 1","pages":"81-94"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11290477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effect of synthetic progestogens on endometrial cancer. Cytochemical criteria].","authors":"J Hustin, J M Binard, R Lambotte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>1) Well-differentiated carcinomas of the endometrium contain acid mucins with carboxyl or, more rarely, sulphated radicals. The latter are found in certain hypersecretory papillary tumours. 2) The neoplastic cells are surrounded by a border rich in acid muco-substances, including sialic acid. This pericellular film is unaffected by progestogens. 3) With progestogen therapy, there is a marked increase in the secretion of muco-substances in sensitive malignant cells. There is also more glycogen in the cytoplasm. No qualitative change in secretion may be demonstrated. 4) The intracytoplasmic accumulation of glycogen and mucopolysaccharide material is inversely proportional to the mitiotic index.</p>","PeriodicalId":75498,"journal":{"name":"Annales d'anatomie pathologique","volume":"22 4","pages":"323-6"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11369195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}