[Electronic microscopic study of a sacral chordoma. Characterization of various development stages of the tumor cells].

Annales d'anatomie pathologique Pub Date : 1977-01-01
J P Thiery, A Mazabraud, J Mignot, M Durigon
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Abstract

The electron microscopic study of a sacral chordoma, the cells of which contain variable amounts of glycogen, allowed to characterize different stages in the evolution of the tumoral cells. The young cells contain almost no glycogen ; progressively it becomes more abundant and fills up almost the whole cytoplasm. At the end of the evolution glycogen disappears while the cell becomes vacuolated. This suggests that enzymatic lysis of this polysaccharide could be the cause of the vacuolation which finally produces the physaliferous cell. Comparison between the cells of the chordoma and those of the normal notochord shows some morphological similarities in the development of these cells. These different data may be useful for a classification of the various types of chordomas.

骶脊索瘤的电子显微镜研究。肿瘤细胞不同发育阶段的表征[j]。
电子显微镜下对骶脊索瘤的研究,其细胞中含有不同数量的糖原,可以表征肿瘤细胞进化的不同阶段。年轻的细胞几乎不含糖原;它逐渐变得越来越丰富,几乎充满了整个细胞质。在进化的最后,糖原消失,细胞变成空泡。这表明这种多糖的酶解可能是液泡化的原因,最终产生了物理细胞。脊索瘤细胞与正常脊索细胞的比较表明,这些细胞在发育过程中有一些形态上的相似性。这些不同的数据可能对不同类型脊索瘤的分类有用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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