{"title":"Disturbances in the function of cardiovascular system in patients following endotracheal intubation and attempts of their prevention by pharmacological bloackade of sympathetic system.","authors":"J Siedlecki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author recorded arterial blood pressure by direct method and ECG in 94 patients during laryngoscopy and intubation. A rise of the mean arterial blood pressure was observed from 104 to 153 mm Hg together with the appearance of ventricular premature beats in patients with normal arterial blood pressure and without arhythmia before the procedure. Superficial analgesia of the pharynx, larynx and trachea failed to prevent the rise of arterial pressure during intubation. The procedure of superficial analgesia connected with intubation caused also a rise in the arterial blood pressure and arrhythmia. Blockade of beta adrenergic receptors reduced the intensity of these disturbances, while blockade of alpha adrenergic receptors increased them. Blockade of the sympathetic ganglia by controlled infusion of trimethaphan (Arfonad) allowed the arterial pressure to be controlled during intubation thus preventing sudden rises and the development of arrhythmia. The author suggests that a sudden rise in the arterial blood pressure during endotracheal intubation may cause rupture of aortic or intracranial aneurysms. The rise of arterial blood pressure precedes the appearance of ventricular premature beats caused by stimulation of the pharynx, larynx and trachea.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 2","pages":"107-23"},"PeriodicalIF":0.0,"publicationDate":"1975-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12357668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hyperventilation in neurosurgery.","authors":"K Moszyński, W Lewelt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An outline of the nature and varieties of hyperventilation is presented together with a discussion on the role of artificial hyperventilation in the management of neurosurgical patients. Attention is called to the value of gasometric investigations in the ventricular cerebrospinal fluid for evaluation of disturbances in pH of the intracranial environment and possible effectiveness of hyperventilation. The results of our measurements of cerebrospinal fluid pressure are presented in 21 cases of supratentorial cerebral tumours in which controlled ventilation with hyperventilation was conducted. In 19 cases, the cerebrospinal fluid pressure fell by a mean of 44.3% with a simultaneous fall of PaCO2 by 29.3%. In the conclusions the authors stress the role of hyperventilation in the lowering of raised cerebrospinal fluid pressure and prevention of cerebral oedema.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 2","pages":"135-40"},"PeriodicalIF":0.0,"publicationDate":"1975-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11455719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical evaluation of the action of dexamethasone.","authors":"S Kopczyński, E Kurzaj, D Lipińska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The antioedematous action of dexamethasone was assessed in 28 patients with supratentorial and infratentorial intracranial tumours and craniocerebral trauma. The criteria of evaluation included the state of consciousness, signs of focal cerebral injury, autonomic disturbances and signs of raised intracranial pressure. The greatest improvement was obtained in patients having intracranial tumours with herniation of the brain stem. In cases of extensive craniocerebral trauma no evident improvement was achieved.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 2","pages":"157-63"},"PeriodicalIF":0.0,"publicationDate":"1975-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11389509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Professor Vladimir Alexandrovitch Negovski, M.D. Doctor of Medicine (Honoris Causa) of the Medical Academy in Poznań.","authors":"W Jurczyk","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 1","pages":"87-8"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12278378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of dynamic compliance of lungs and disturbances of breathing mechanics in patients following laryngectomy for carcinoma of the larynx.","authors":"S Woźniak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of study was to observe changes which may develop in the mechanics of breathing following laryngectomy in patients with carcinoma of the larynx as compared with the pre-operative conditions. The studies were carried out on a group of 29 patients, performing the measurements twice, i.e. before operation and after laryngectomy and tracheostomy. The measurements were done using a Godart Compliance-Test type 121 apparatus. The value of the coefficient of dynamic compliance of the lungs was determined together with the magnitude and type of work necessary to overcome respiratory resistance. It was found that after the operation the coefficient of dynamic compliance of the lungs increased by 63.7% while the total work of breathing decreased by 38.7% and the work necessary to overcome the elastic resistance of the lungs fell by 33.7% and that for overcoming the non-elastic resistance fell by 49.3%. The most significant changes in breathing mechanics observed after the operation concerned the ratio or breathing work necessary to overcome the non-elastic resistance to the total breathing work. This ratio was 43.35% pre-operatively and 34.11% post-operatively. The obtained results suggest that impairment of laryngeal patency caused by the tumour raises the breathing work and reduces the coefficient of dynamic compliance of the lungs due mainly to an increased non-elastic breathing resistance.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 1","pages":"43-55"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12333024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of controlled respiration by the manual technique and with a respirator during general anaesthesia for abdominal operations.","authors":"W Rychlewski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>These studies investigating the difference between controlled respiration performed by manual technique and controlled respiration applied by means of a respirator during general anaesthesia, and assessing the influence of these methods on the immediate post-operative condition of the patient were carried out on 75 patients during abdominal operations. Gasometric tests in arterial blood were performed before premedication, at intervals of 30 min from the beginning of operation, and 10 min. after the removal of the endotracheal tube. Controlled respiration with a respirator is a more favourable method of pulmonary ventilation during general anaesthesia given for a long-lasting surgical operation. The manual technique of controlled respiration leads to respiratory alkalosis. The best results were obtained using a respirator with inspiratory volume of 10 ml/kg and respiratory frequency 10/min., which ensured normocapnia. It was observed that oxygenation of arterial blood was reduced postoperatively in all patients but the value of PaO2 was the lowest in patients on manual controlled respiration. Disturbances in acid-base balance and oxygenation had an unfavourable effect and delayed the regaining of consciousness.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 1","pages":"57-68"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11454453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of artifical ventilation and dehydrobenzperidol on the development of early changes in the respiratory system in dogs with Mendelson's syndrome.","authors":"W Budych","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The experiments were carried out to observe certain functional changes in the respiratory system which develop in the early stage of aspiration pneumonia and to study the possibility of influencing these changes by application of artificial ventilation (IPPB) and/or administration of dehydrobenzperidol. The experiments were carried out on 32 mongrel dogs divided into 4 groups. Experimental Mendelson's syndrome was produced by instilling, during anaesthesia, hydrochloric acid solution of pH 1.5 in a dose of 4 ml/kg into the tracheobronchial tree. Immediately after anaesthesia and then 10 times at intervals of one hour after HCl instillation the following determinations were done: mean blood pressure, CVP, haematocrit, PO2 and PCO2 in arterial and mixed venous blood, and minute artifical ventilation. The veno-arterial blood shunt in the lungs, alveolo-arterial difference of oxygen partial pressure and the effective compliance were also determined. The chemical damage to the lungs by acid caused condensation of blood and a fall in CVP. These changes were due to fluid escape from the vessels especially in the pulmonary vascular tree. Disturbances in pulmonary gas exchange were a result of deficient ventilation of lung areas damaged primarily by acid and suffering secondarily from developing disturbances in pulmonary blood flow. Dehydrobenzperidol in a dose of 1 mg/kg applied as the only treatment in Mendelson's syndrome had the same favourable effect on pulmonary changes as controlled IPPB. The combination of controlled artificial ventilation and intravenous dehydrobenzperidol decreased the disturbances in pulmonary gas exchange in Mendelson's syndrome. This was possible because both factors exert a benficial effect on ventilation and perfusion preventing the development of oedema and atelectasis.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 1","pages":"15-23"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11454451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of arterial blood oxygenation in various states of acute respiratory failure.","authors":"W E Tumalewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study contains an analysis of the clinical course of 48 patients with acute respiratory failure. The degree of arterial hypoxaemia and respiratory failure were correlated with the value of true pulmonary shunt of non-oxygenated blood. Measurements of the shunt were carried out serially during treatment and it was calculated from the shunt equation of Berggren. It was found that the pulmonary shunt is a good index of arterial blood oxygenation in cases of acute respiratory failure. The value of 47% of shunt was accepted as that with is incompatible with survival. It was demonstrated that determinations of pulmonary shunt are superior to A-aP02 measurements in assessment of the ventilatory function of the lungs.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 1","pages":"25-33"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12333965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in the dynamic compliance coefficient of the lungs and breathing mechanics during administration of diethyl ether and halothane for general anaesthesia with spontaneous respiration.","authors":"A Budniewski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Changes of the dynamic compliance coefficient of lungs were studied during diethyl ether and halothane anaesthesia. Determining lung compliance at the same time it was possible to show the effect of these agents on changes in the magnitude of breathing work necessary to overcome elastic and non-elastic resistances. The investigations were carried out on 31 patients during general anaesthesia with spontaneous respiration. The determinations revealed that the tidal volume (TV) was decreased in relation to the initial values (before anaesthesia) indicating a depressing effect of these agents on the processes of respiration. Changes in the tidal volume and intrapulmonary pressure decided on the changes of the pulmonary compliance coefficient and the magnitude of breathing work. The coefficient of pulmonary compliance decreased during diethyl ether administration by 18.8% and during halothane by 30.9%. On the other hand the work necessary to overcome respiratory resistances increased mainly during ether anaesthesia owing to a significant rise in the non-elastic resistance (bronchial secretion).</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 1","pages":"35-41"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12333023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Morphological changes of tracheobranchial mucosa in dogs caused by breathing through a surgically produced tracheal fistula.","authors":"A Kakomy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author studied the morphological changes developing in the tracheobronchial mucosa following a surgical tracheal fistula. The experiments were carried out on 19 dogs which were divided into 2 groups. Group I included 10 dogs, in which specimens were obtained by bronchoscopy; in group II, 9 dogs, specimens were obtained directly. Histological examinations were carried out by Gomori's reaction and hematoxylin-eosin staining method. Histo-chemical tests included PAS reaction and alcian blue stain. The results showed that after 24 hours morphological changes mainly involved the tracheal mucosa and their characteristic feature was the variety of forms of lesions of the epithelium covering the mucosa. The longer the duration of the fistula the more these changes increased in intensity and involved further parts of the tracheobronchial tree. The author also took into account the living conditions in the kennels where the dogs were kept following the tracheostomy. The changes observed were compared with those reported by other authors and the correlation between the occurrence of these changes and the environmental conditions and length of breathing through the surgically produced fistula was analysed.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 1","pages":"3-14"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12333966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}