{"title":"Studies of blood clotting system during dissociative anaesthesia with ketamine.","authors":"W Gaszynski, D Jezewska, A Kanski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of ketamine administered to 20 rabbits in a single dose and in fractionated doses on the blood clotting system was studied. The following blood clotting indices were determined: thrombelastography (TEG), plasma thrombin time, platelet count, euglobulin lysis time. No statistically significant differences were observed in the activity of clotting and fibrinolysis systems in the group of animals receiving a single dose of ketamine and in the group receiving fractionated doses. The obtained results suggest that ketamine as an agent used for dissociative anaesthesia can be administered safely in serious conditions associated with disturbances in the haemostasis system.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"4 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12152531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A simple device designed to protect operating theatres against atmospheric pollution by volatile anaesthetics.","authors":"J Karski, M Sych","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors worked out and applied a new device of positive pressure valve encased in the rebreathing circuit and one-way Ruben's valve, as well as a modification of Rees's system making it possible to conduct excess gases containing anaesthetics outside the operating theatre. These devices and modifications are completely reliable owing to their simplicity and their construction is cheap. They effectively reduce the degree of atmospheric pollution in the operating theatre with anaesthetics used in inhalation anaesthesia. They may be applied to every type of apparatus used for general anaesthesia.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"4 1","pages":"61-4"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12153487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Luczak, T Dziegielewski, L Drobnik, W Grabus, R Siennicki, J Kocur-Kolinska
{"title":"The use of respirators in patients with complicated myocardial infarction.","authors":"J Luczak, T Dziegielewski, L Drobnik, W Grabus, R Siennicki, J Kocur-Kolinska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of controlled respiration as treatment in 20 patients with complicated myocardial infarction are presented. The clinical indications to this method of treatment included: shock, pulmonary oedema refractory to treatment, recurrent ventricular fibrillation and respirator failure following cardiac arrest. An indication for the use of this method is a drop in PaO2 below 70 mm Hg despite breathing 30% oxygen. Neuroleptanalgesic drugs were administered routinely while the patient was on the respirator. In all cases at least two prognostically unfavourable clinical signs were found. A correlation was observed between the clinical result and hypoxaemia after breathing 100% oxygen.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"4 1","pages":"35-40"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12247272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plasminogen activators and urokinase inhibitors in the lungs of foetuses and newborns.","authors":"R Uszynska-Folejewska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The concentrations of plasminogen activators and urokinase inhibitors were determined in histological sections of 87 foetuses and newborns. It was found that urokinase inhibitors are a constant component of lung tissue in foetuses in the 2nd and 3rd trimesters of pregnancy and in newborns. With progressing maturation of foetuses the concentration of urokinase inhibitors diminishes and, as a rule, the concentration of inhibitors is scores of times higher than that of activators.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"4 1","pages":"41-5"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12152533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of acupuncture as a method of analgesia during operation.","authors":"M Borzecki, J Kacki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors evaluated the method of acupuncture used for analgesia in various types of minor and major surgical operations in patients not previously tested for determination of susceptibility for this method. The report is a preliminary communication. For major operations the patients received premedication and during the operation they received additional local or general analgesics. Out of 13 patients in various age groups 5 evaluated this analgesia as very good and in 3 cases the degree of analgesia obtained was not sufficient to perform the operation. The authors regard that acupuncture has found its main application principally in the treatment of chronic pain, while as a method of analgesia for surgical operations it has many disadvantages and requires further experiences. The authors observed also certain features of acupuncture analgesia not observed in conventional methods of nerve conduction blockade, which may contribute to the explanation of the mechanism of acupuncture.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"4 1","pages":"53-60"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12153488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comparative study of intravenous anaesthesia with thiopental versus althesin in outpatient dental practice.","authors":"S Orzechowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Clinical effects of two intravenous anaesthetics--thiopental and althesin--were compared in a group of 160 outpatients. Each anaesthetic was used in 80 cases. The administration of these anaesthetics was preceded by an intravenous injection of fentanyl and atropine sulphate. Anaesthesia was carried out with the patient sitting in dental chair. The observations confirmed that this method of anaesthesia provides good conditions for carrying out minor dental operations and is safe for the patient, as evidenced by a negligible number of minor complications. A comparison of the results of clinical observations and gasometric determinations indicates that althesin is superior in outpatient practice to thiopental. This simple and easy technique of anaesthesia without the necessity of using expensive apparatus should be widely introduced in outpatient practice.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"4 1","pages":"11-24"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12152529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Polocki, J Niewinska, I Miksza, A Borucka, H Dudek
{"title":"The effect of methoxyflurane on certain renal function parameters.","authors":"B Polocki, J Niewinska, I Miksza, A Borucka, H Dudek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 43 patients the effect of low concentrations of methoxyflurane on the renal function was studied. The blood levels of urea, creatinine, uric acid, sodium and potassium, and specific weight of urine was determined. It was found that the anaesthetic technique used and methoxyflurane concentrations in the range of 0.2-0.5 vol% caused no abnormalities in renal function. It seems that methoxyflurane in low concentrations (0.2-0.5 vol%) is the best method of anaesthesia with this agent, with the simultaneous use of a nitrous oxide-oxygen mixture and controlled ventilation.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"4 1","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12152532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Studies of blood clotting system during anaesthesia for prostatectomy. I. Epidural analgesia.","authors":"W Gaszyński, J Lisicki, A Zalewski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The studies were carried out on 20 patients operated on for prostatic adenoma under epidural analgesia. It was observed that activation of the fibrinolytic system is due to trauma to the prostate and is connected with release of plasmin activators into circulating blood. Epidural analgesia has no effect on the blood clotting and fibrinolysis systems and is a safe method in prostatectomy.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 4","pages":"357-60"},"PeriodicalIF":0.0,"publicationDate":"1975-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11281093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of halothane on active transport of sodium in the epithelial cell.","authors":"R Szulc, J Knapowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors studied the effect of halothane on active transport of sodium in the epithelial cells using the method described by Ussing with frog skin as an experimental model. It was found that the action of the anasthetic agent on the active transport of sodium was biphasic, and this observation confirmed the results obtained with another experimental model. It was observed, moreover, that the mechanism of halothane action on the cell membrane it not identical with that of vasopressin, which was used in some of the present experiments before adding halothane. The present investigations suggest that halothane acts primarily on the cell membrane and not on the deeper situated intracellular structures.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 4","pages":"279-83"},"PeriodicalIF":0.0,"publicationDate":"1975-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12405277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Flunitrazepam, a new benzodiazepine compound in general anaesthesia. Clinical and statistical considerations on the first thousand cases.","authors":"R Rizzi, G Butera, P Lion, F Pesarin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Flunitrazepam, a derivative of benzodiazepine was used for induction and maintenance of anaesthesia in 933 patients. The induction dose was from 1,786 to 2,053 mg. The total dose of 2-2.66 mg was sufficient for maintenance of hypnosis for about 2 hours. The undesirable side effects were very rare. The average time of hypnosis after a single dose of flunitrazepam was 50.1 sec. The sedative action of the drug lasted for some time after regaining of consciousness. In most patients there was no need for administration of analgetics during first 24 hours after the operation. The authors believe that surgical anaesthesia will greatly benefit from this drug.</p>","PeriodicalId":75483,"journal":{"name":"Anaesthesia, resuscitation, and intensive therapy","volume":"3 4","pages":"339-56"},"PeriodicalIF":0.0,"publicationDate":"1975-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11231370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}