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Advances in lipid research最新文献

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Sphingosine kinase: properties and cellular functions. 鞘氨醇激酶:性质和细胞功能。
Advances in lipid research Pub Date : 1993-01-01
B M Buehrer, R M Bell
{"title":"Sphingosine kinase: properties and cellular functions.","authors":"B M Buehrer, R M Bell","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"26 ","pages":"59-67"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19382507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sphingolipids with inositolphosphate-containing head groups. 含有肌醇磷酸基团的鞘脂。
Advances in lipid research Pub Date : 1993-01-01
R L Lester, R C Dickson
{"title":"Sphingolipids with inositolphosphate-containing head groups.","authors":"R L Lester,&nbsp;R C Dickson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>InsPCers have been characterized in many plants, fungi, and protozoans but not in animals. There are no well-documented reports of the absence of InsPCers in organisms of these categories and one might possibly consider these lipids to be ubiquitous in plants, fungi, and protozoans. The polar headgroups of these lipids display quite heterogeneous structures depending on the source, including attachment to proteins as possible membrane anchors. The ceramides are with some exceptions composed of phytosphingosine and a very long-chain, usually hydroxylated, fatty acid. The vital nature of such sphingolipids in the plasma membrane is indicated in S. cerevisiae. Clearly, much remains to be discovered about the structure, metabolism, and function of the InsPCers.</p>","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"26 ","pages":"253-74"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19365196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sphingolipid regulation of the epidermal growth factor receptor. 鞘脂对表皮生长因子受体的调节。
Advances in lipid research Pub Date : 1993-01-01
R J Davis
{"title":"Sphingolipid regulation of the epidermal growth factor receptor.","authors":"R J Davis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"25 ","pages":"131-45"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19380382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The novel second messenger ceramide: identification, mechanism of action, and cellular activity. 新型第二信使神经酰胺:鉴定、作用机制和细胞活性。
Advances in lipid research Pub Date : 1993-01-01
Y A Hannun, L M Obeid, R A Wolff
{"title":"The novel second messenger ceramide: identification, mechanism of action, and cellular activity.","authors":"Y A Hannun,&nbsp;L M Obeid,&nbsp;R A Wolff","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"25 ","pages":"43-64"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19380385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ceramide: a novel second messenger. 神经酰胺:一种新的第二信使。
Advances in lipid research Pub Date : 1993-01-01
S Mathias, R Kolesnick
{"title":"Ceramide: a novel second messenger.","authors":"S Mathias,&nbsp;R Kolesnick","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The data discussed in the preceding sections suggest that information may be transmitted both through synthesis and through degradation of sphingomyelin. Although the sphingomyelin pathway holds promise as a new signaling system coupling TNF receptor activation to cellular stimulation (Fig. 5), the work is still at a preliminary stage. A physical association of receptors with neutral sphingomyelinase has yet to be established and the ceramide-activated protein kinase has yet to be isolated. Endogenous substrates for the kinase have also to be identified. Furthermore, the exact role of this pathway has not been defined. It is unclear whether this pathway is specific to monocyte differentiation or cytokine action. It also seems unlikely that a single signal transduction mechanism can account for all the diverse effects of TNF-alpha in different systems (Vilcek and Lee, 1991). Interactions with other signaling systems are sure to complicate elucidation of the exact role(s) of this pathway. Nevertheless, availability of cell-permeable analogs of ceramide, localization of many components of the system at the cell surface, and recent development of anti-TNF receptor antibodies to receptor isotypes may allow for greater definition of the sphingomyelin pathway in the near future.</p>","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"25 ","pages":"65-90"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19354773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances. PDMP等物质抑制糖基神经酰胺合成的代谢作用。
Advances in lipid research Pub Date : 1993-01-01
N S Radin, J A Shayman, J Inokuchi
{"title":"Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances.","authors":"N S Radin,&nbsp;J A Shayman,&nbsp;J Inokuchi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"26 ","pages":"183-213"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19364575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sphingosine-phosphate lyase. Sphingosine-phosphate裂合酶。
Advances in lipid research Pub Date : 1993-01-01
P P van Veldhoven, G P Mannaerts
{"title":"Sphingosine-phosphate lyase.","authors":"P P van Veldhoven,&nbsp;G P Mannaerts","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"26 ","pages":"69-98"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19365202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracellular transport of ceramide and its metabolites at the Golgi complex: insights from short-chain analogs. 高尔基复合体中神经酰胺及其代谢物的细胞内转运:来自短链类似物的见解。
Advances in lipid research Pub Date : 1993-01-01
A G Rosenwald, R E Pagano
{"title":"Intracellular transport of ceramide and its metabolites at the Golgi complex: insights from short-chain analogs.","authors":"A G Rosenwald,&nbsp;R E Pagano","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"26 ","pages":"101-18"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19364571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Truncated ceramide analogs as probes for sphingolipid biosynthesis and transport. 截断神经酰胺类似物作为鞘脂生物合成和运输的探针。
Advances in lipid research Pub Date : 1993-01-01
D Jeckel, F Wieland
{"title":"Truncated ceramide analogs as probes for sphingolipid biosynthesis and transport.","authors":"D Jeckel,&nbsp;F Wieland","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"26 ","pages":"143-60"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19364573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gangliosides and modulation of the function of neural cells. 神经节苷类与神经细胞功能的调节。
Advances in lipid research Pub Date : 1993-01-01
G Tettamanti, L Riboni
{"title":"Gangliosides and modulation of the function of neural cells.","authors":"G Tettamanti,&nbsp;L Riboni","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75444,"journal":{"name":"Advances in lipid research","volume":"25 ","pages":"235-67"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19354769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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