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Acta vitaminologica et enzymologica最新文献

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Dysplastic and degenerative diseases: the protective role of vitamins A and E. Rome, January 25, 1986. 发育不良和退行性疾病:维生素A和e的保护作用。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
{"title":"Dysplastic and degenerative diseases: the protective role of vitamins A and E. Rome, January 25, 1986.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14958483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regression of bronchial epidermoid metaplasia in heavy smokers with etretinate treatment. 用异维甲酸治疗重度吸烟者支气管表皮样化生的消退。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
J L Misset, G Mathé, G Santelli, J Gouvela, J P Homasson, M C Sudre, H Gaget
{"title":"Regression of bronchial epidermoid metaplasia in heavy smokers with etretinate treatment.","authors":"J L Misset,&nbsp;G Mathé,&nbsp;G Santelli,&nbsp;J Gouvela,&nbsp;J P Homasson,&nbsp;M C Sudre,&nbsp;H Gaget","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>40 voluntary heavy smokers (over 15 packets-years) were selected for and have completed a six months etretinate treatment on the basis of an index of metaplasia (IM) greater than 15% determined according to the following procedure: bronchoscopy with systematic biopsies in 10 sites of the bronchial tree. Each biopsy was cut into 10 sections and an IM was calculated: (Formula: see text). Etretinate, a retinoid derivative, was given orally at the daily dose of 25 mg, at the end of which they underwent a second fibroscopy protocol. A highly significant reduction of IM (p = 10(-5)) was observed after 6 months of treatment for those of the patients who maintained their smoking habits during treatment. Besides, the 4 patients who stopped smoking while under treatment and are excluded from the statistical analysis, all had a complete regression of metaplasia at the second fibroscopy. No morbidity was due to etretinate or fibroscopy. Etretinate significantly reduces potentially precancerous bronchial epidermoid metaplasia in heavy smokers. Its association with smoking arrest may induce a rapid restoration of bronchial epithelium to normal.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14958484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin A deficiency and sensory function. 维生素A缺乏和感觉功能。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
H K Biesalski, U Wellner, E Stofft, K H Bässler
{"title":"Vitamin A deficiency and sensory function.","authors":"H K Biesalski,&nbsp;U Wellner,&nbsp;E Stofft,&nbsp;K H Bässler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Morphological investigation of tongue, olfactory epithelia, trachea and inner ear in vitamin A deficiency are reported. The results support assumptions concerning the loss of sensory function as been at least a secondary effect of alterations of the neighbourhood of the sensory cells caused by vitamin A deficiency. Taste buds are hindered in function by a dense layer of squamous cells and olfaction is decreased by atrophy of the surrounding respiratory epithelium. Inner ear functionality seems to be affected by vitamin A status via a stabilizing effect on the endolymph-perilymph barrier.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15031102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liberation of prostaglandin-like substances from the isolated coronary artery in presence of angiotensin and of 4-methylesculetin. 前列腺素样物质在血管紧张素和4-甲基维甲素存在下从离体冠状动脉释放。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
V Bettini, L Calò, S Cantaro, R Martino, L Munari, E Salvatico, P Ton
{"title":"Liberation of prostaglandin-like substances from the isolated coronary artery in presence of angiotensin and of 4-methylesculetin.","authors":"V Bettini,&nbsp;L Calò,&nbsp;S Cantaro,&nbsp;R Martino,&nbsp;L Munari,&nbsp;E Salvatico,&nbsp;P Ton","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this work is to study the mechanism by which 4-Methylesculetin (4-ME) causes the relaxation or inhibits the Angiotensin II (ATN 2) induced contraction in the smooth muscle. The effect of 4-Me, alone or associated with Ascorbic Acid, on basal tone and ATN 2 induced contraction of isolated coronary strips have been studied. Experiments have been carried out in presence of Lysine Acetylsalicylate (LAS) and Indomethacin (IN), known inhibitors of prostaglandin-synthetase. Both LAS and IN decrease but not abolish, the 4-ME induced relaxation and suppressed the depressive effect of 4-ME on the ATN 2 dependent contraction. From R.I.A. tests results that 6-Keto PGF1 alpha (prostacyclines stable metabolite) concentration increased with the addition of 4-ME to the bath. 6-Keto PGF1 alpha concentration was drastically reduced after IN and LAS use. Therefore, it seems reasonable to conclude that 4-ME influence could be mediated by prostacyclines release in the smooth muscle.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15051022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"ESVITAF". Survey on the vitamin status of the French: relationships between nutrient intake and biochemical indicators. “ESVITAF”。法国人维生素状况调查:营养摄入与生化指标的关系。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
B Herbeth, G Potier de Courcy, J Sancho, M Bourgeay-Causse, G Carreguery, N Chau, E Delacoux, C Le Devehat, A Lemoine, J P Mareschi
{"title":"\"ESVITAF\". Survey on the vitamin status of the French: relationships between nutrient intake and biochemical indicators.","authors":"B Herbeth,&nbsp;G Potier de Courcy,&nbsp;J Sancho,&nbsp;M Bourgeay-Causse,&nbsp;G Carreguery,&nbsp;N Chau,&nbsp;E Delacoux,&nbsp;C Le Devehat,&nbsp;A Lemoine,&nbsp;J P Mareschi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The relationships between dietary data and biochemical nutritional status for vitamins B1, B2, A, E, beta-carotene, folic acid and iron have been studied using data from a survey conducted on 710 adults. Significant correlations were found between riboflavin intake and biochemical values for males only (r = -0.105, p less than or equal to 0.05), between beta-carotene intake and plasma beta-carotene (r = 0.232, for males and r = 0.292 for females, p less than or equal to 0.001), and between iron intake and plasma iron for males only (r = 0.115, p less than or equal to 0.05). Concerning nutrient densities, correlations were significant between dietary riboflavin and biochemical measure (r = 0.163, p less than or equal to 0.01 for males, r = -0.135, p less than or equal to 0.05 for females), between vitamin A intake (expressed in retinol equivalent) and beta-carotene (r = 0.212, p less than or equal to 0.001 for males, r = 0.157, p less than or equal to 0.01 for females) and for males only, between dietary iron and hemoglobin (r = 0.144, p less than or equal to 0.01). The dietary data for each nutrient were examined for their sensitivity, specificity and predictive values in identifying subjects with substandard or overstandard biochemical values. For all nutrients the positive predictive value percentage was always below 25%, the negative predictive value percentage always under 75%.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15202437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Therapeutic effects of vitamin A associated with vitamin E in perceptual hearing loss]. [维生素A与维生素E联合治疗感性听力损失的疗效]。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
G Romeo, M Giorgetti
{"title":"[Therapeutic effects of vitamin A associated with vitamin E in perceptual hearing loss].","authors":"G Romeo,&nbsp;M Giorgetti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Forty patients (25 men and 15 women, age 39 to 70) affected by presbycusis (in 7 cases associated with transmission defects) have been treated with vitamins A and E for 28-48 days. At the end of the therapy an improvement of symptoms, an in some cases of the audiometric record, have been observed.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15014945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the non-absorbable fat, (sucrose polyester), interfere with the intestinal absorption of vitamin A? 不可吸收的脂肪(蔗糖聚酯)会干扰肠道对维生素A的吸收吗?
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
E G Sletten, D Hollander, V Dadufalza
{"title":"Does the non-absorbable fat, (sucrose polyester), interfere with the intestinal absorption of vitamin A?","authors":"E G Sletten,&nbsp;D Hollander,&nbsp;V Dadufalza","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sucrose polyester (SPE) is a synthetic non-absorbable lipid. The effect of SPE on vitamin A absorption was determined by monitoring the disappearance rate of radio-labeled vitamin A from the jejunal perfusate of the rat. The relative distribution of radio-labeled vitamin A between the micellar phase and the perfusate containing SPE was determined. With SPE concentrations of 5, 10 and 20 g/l, vitamin A was concentrated in the SPE phase over the micellar phase by a factor of 4.4, 9.4, 19.8 respectively. Thus, vitamin A favored the SPE phase over the micellar phase in the distribution analysis. In vivo absorption experiments with SPE and non-SPE perfusates showed decreased net vitamin A absorption rates in the presence of SPE by 8.7% Thus, dietary ingestion of SPE results in some impairment of intestinal absorption of vitamin A, and may require vitamin A supplementation.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15149372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repletion and depletion of serum alpha and beta carotene in humans with carrots and an algae-derived supplement. 胡萝卜和藻类衍生补充剂对人体血清α和β胡萝卜素的补充和消耗。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
C D Jensen, T S Pattison, G A Spiller, J H Whittam, J Scala
{"title":"Repletion and depletion of serum alpha and beta carotene in humans with carrots and an algae-derived supplement.","authors":"C D Jensen,&nbsp;T S Pattison,&nbsp;G A Spiller,&nbsp;J H Whittam,&nbsp;J Scala","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 10-day low-carotene diet phase (LCD), followed by a 7-day treatment phase (TP) and then another LCD, was adhered to by 32 adult human subjects. Serum alpha carotene (SAC) and serum beta carotene (SBC) levels were examined using HPLC and found to have decreased 44.7% and 35.8% respectively in the first LCD. Alpha and beta carotene, from algae-derived capsules and raw carrots, significantly increased SAC and SBC levels during the TP. Half-lives of SAC and SBC averaged 7.8 days and 12.4 days respectively during the two LCD. Serum vitamin A remained unchanged throughout the study.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15202565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationships between biotin and DNA contents and DNA turnover in lymphoid organs: thymus, lymph nodes and spleen. 生物素与胸腺、淋巴结和脾脏等淋巴器官DNA含量及DNA更新的关系。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
F Petrelli, P Moretti, P Sciarresi, A M Dahir
{"title":"Relationships between biotin and DNA contents and DNA turnover in lymphoid organs: thymus, lymph nodes and spleen.","authors":"F Petrelli,&nbsp;P Moretti,&nbsp;P Sciarresi,&nbsp;A M Dahir","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Biotin-deficient rats show a slower growth rate and a reduction in thymus, intestinal lymph nodes and spleen weight. The effect is reversible. Biotin administration to normal rats (1 mg/rat/day) causes an increase in intestinal lymph nodes and spleen, while there is no effect on body and thymus weight. The amount of thymus and spleen DNA is lower for deficient than control rats. No difference was noticed between the levels of DNA from normal control and biotin-deficient rat lymph nodes, and between the levels of DNA from normal rats treated and untreated with biotin. The time-course of the specific radioactivity of DNA and the DNA turnover shows that biotin increases both the incorporation of labelling in DNA and DNA turnover rate.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15202566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental pattern of the hepatic DNA, RNA and protein in relation to maternal vitamin A status in rats. 大鼠肝脏DNA、RNA和蛋白质的发育模式与母体维生素A状态的关系。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
H S Sharma, U K Misra
{"title":"Developmental pattern of the hepatic DNA, RNA and protein in relation to maternal vitamin A status in rats.","authors":"H S Sharma,&nbsp;U K Misra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of maternal vitamin A restriction on the biochemical development of fetal liver in rats has been studied. Vitamin A status of the dams has been varied by supplying low, medium and adequate (6.40 and 100 micrograms retinol equivalents/day/kg body weight respectively) amounts of vitamin A during pregnancy and suckling. The restricted supply of vitamin A to the mother resulted in the impaired growth and development of fetal liver in the parameters of tissue weight, DNA, RNA and protein levels, cell number and biosynthesis of DNA and protein from 3H-thymidine and 3H-leucine respectively. Results also indicated a dose dependent effect of vitamin A on the metabolism of DNA, RNA and protein in the developing liver.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13561301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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