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Acta Universitatis Carolinae. Medica最新文献

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Arthroscopic synovectomy in the treatment of patients with juvenile rheumatoid arthritis. 关节镜下滑膜切除术治疗幼年类风湿性关节炎。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
P Vilkki, R Virtanen, A L Mäkelä
{"title":"Arthroscopic synovectomy in the treatment of patients with juvenile rheumatoid arthritis.","authors":"P Vilkki,&nbsp;R Virtanen,&nbsp;A L Mäkelä","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since January 1982, operative arthroscopy in the knee joint has been performed by us to 22 patients with juvenile rheumatoid arthritis, by whom synovectomy was considered to be indicated. The age of the patients varied from 5 to 16 years. In general anaesthesia, in the connection of arthroscopy, the abrasion of the hypertrophic synovial membrane was made by Stryker's chondrotome. The surgical debris was evacuated by suction. The mobilisation of the knee joint was started 2 days after the operation, and most of the patients walked on the fifth postoperative day. The arthroscopic synovectomy is considered to be a safe operation and, in our opinion, a good alternative method for synovectomy. Rehabilitation time is decisively shorter and, if necessary, operative arthroscopy can easily be repeated, without disturbing scars.</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"84-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13006615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripheral blood lymphocyte subpopulations in children with juvenile chronic arthritis. 青少年慢性关节炎患儿外周血淋巴细胞亚群。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
K Nagy, L Kassay, E Berkes, L Velkey
{"title":"Peripheral blood lymphocyte subpopulations in children with juvenile chronic arthritis.","authors":"K Nagy,&nbsp;L Kassay,&nbsp;E Berkes,&nbsp;L Velkey","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Peripheral blood lymphocyte subset levels were analyzed in 28 patients with active, polyarticular, juvenile chronic arthritis and in 12 healthy control children. The patients with a similar treatment were divided into two groups, at the beginning of disease and after five years course. Ten children with juvenile chronic arthritis were treated by glucocorticosteroid. After five years the percentage of active T cells, T suppressor cells and active (total T cells ratio were significantly elevated and there was a same decrease in the T4/T8 ratio. Glucocorticosteroid increased proportion of active T cells but it did not change the percentage of other lymphocyte subsets. It is concluded that during the course of disease a drug-induced or spontaneous effect appears which corrects the initial immunological disturbances.</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"50-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13006766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Free radicals in children with rheumatic diseases in serum and synovial fluid. 风湿病患儿血清及滑液中自由基的研究。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
M John, V John, M Apelt
{"title":"Free radicals in children with rheumatic diseases in serum and synovial fluid.","authors":"M John,&nbsp;V John,&nbsp;M Apelt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Free radicals, demonstrable by thiobarbituric acid, are also significant in the pathogenic concept of juvenile chronic arthritis. 41 patients without therapy demonstrate significantly increased values in serum, compared with the same patients after a treatment of 4 weeks. There are relations between ESR and the concentration of thiobarbituric acid reactive substances in serum, but without statistic significance. In the synovial fluid the radicals are increasingly demonstrable, but there is no relation to the number of cells or granulocytes.</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"57-60"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13006767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measurement of the inflammatory activity by the help of serum acute-phase proteins in juvenile chronic arthritis. 用血清急性期蛋白测定青少年慢性关节炎的炎症活性。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
K Nagy, L Kassay, L Velkey
{"title":"Measurement of the inflammatory activity by the help of serum acute-phase proteins in juvenile chronic arthritis.","authors":"K Nagy,&nbsp;L Kassay,&nbsp;L Velkey","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We measured the level of serum haptoglobin, transferrin, alfa-I antitrypsin, orosomucoid, beta-2-microglobulin, ferritin in the case of 30 children (aged 11-16 years) with juvenile chronic arthritis. We divided the patients into two groups. In the first group there were 15 patients with active disease under continuous treatment and in clinical remission (We 20 mm/hour). In the second group there were 15 patients without active disease and they were not given continuous treatment for two Years. These groups were studied, by a control one. If we measure more phase-proteins together, they are suitable for the demonstration of the inflammatory activity in juvenile chronic arthritis. We made a points system for the evaluation of activity.</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"41-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12890973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperlipidemia, dyslipoproteinemia and apolipoproteinopathia--classification and risk of atherosclerosis. Part 2: Hypercholesterolemia. 高脂血症、脂蛋白异常血症和载脂蛋白病——动脉粥样硬化的分类和风险第二部分:高胆固醇血症。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
B Choluj, T Votruba
{"title":"Hyperlipidemia, dyslipoproteinemia and apolipoproteinopathia--classification and risk of atherosclerosis. Part 2: Hypercholesterolemia.","authors":"B Choluj,&nbsp;T Votruba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper sums up recent intervention epidemiological studies of primary atherogeneous hypercholesterolemias. The authors include in this category familial hypercholesterolemia, familial combined hyperlipidemia, and polygenous hypercholesterolemia. Individual disorders are thoroughly analyzed in view of their early diagnostics, differential diagnostics and clinical state. The paper also deals with relatively harmless hypercholesterolemias and their clinical and biochemical criteria.</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 3-4","pages":"106-15"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13006499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Behçet's syndrome with childhood onset. 儿童期发病的behaperet综合征。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
R Häfner, H Truckenbrodt
{"title":"Behçet's syndrome with childhood onset.","authors":"R Häfner,&nbsp;H Truckenbrodt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Behçet's syndrome is a multisystemic disease of vasculitic nature. Main symptoms consist of oral and genital ulceration, uveitis and skin lesions, mainly erythema nodosum. Other features may evolve: arthritis, thrombophlebitis, gastrointestinal, cardiovascular and neurologic lesions. The disease usually manifests in early adulthood, childhood onset is rare. There exists a male preponderance and a genetic disposition. The course of Behçet's syndrome in 5 patients with childhood onset is described.</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"25-30"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13006761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Syndrome of secondary polymyositis with leukemia. 继发性多肌炎伴白血病综合征。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
J Starý, S Havelka, O Hrodek, P Vavrincová, M Havlová
{"title":"Syndrome of secondary polymyositis with leukemia.","authors":"J Starý,&nbsp;S Havelka,&nbsp;O Hrodek,&nbsp;P Vavrincová,&nbsp;M Havlová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A boy with neurofibromatosis suffered mumps at the age of 5. A full-blown juvenile polymyositis developed shortly afterwards. First hematological consultation was done for monocytosis in peripheral blood at the age of 7. He suffered varicella at the age of 8. Diagnosis of acute nonlymphocytic leukemia with monosomy 7 was done before the age of 9. The boy died at the age of 10.</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"16-20"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13006759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of sulphasalazine in patients with juvenile chronic arthritis (JCA). 磺胺嘧啶治疗青少年慢性关节炎的疗效。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
L Settas, P Alexiou, G Dimitriadis, E Mata-Tsi, E Souliou, J Papapanagiotou, A Tourkantonis
{"title":"Effect of sulphasalazine in patients with juvenile chronic arthritis (JCA).","authors":"L Settas,&nbsp;P Alexiou,&nbsp;G Dimitriadis,&nbsp;E Mata-Tsi,&nbsp;E Souliou,&nbsp;J Papapanagiotou,&nbsp;A Tourkantonis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"76-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12852889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peculiarities of dermatomyositis (DM) in early age. 早期皮肌炎(DM)的特点。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
T V Ryabova, M V Velikoretskaya, L I Kotova
{"title":"Peculiarities of dermatomyositis (DM) in early age.","authors":"T V Ryabova,&nbsp;M V Velikoretskaya,&nbsp;L I Kotova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The peculiarities of beginning of disease, clinical factors of risk in 70 children (aged under 8) with dermatomyositis are discussed. We have followed up 70 children (40 girls and 30 boys) with dermatomyositis at the age of 14 months to the age of 8 years. Most of the children were born in normal time, they have normal life functions during the first year of life. The most frequent intercurrent diseases were respiratory infections, angina; the chicken-pox was frequent too. 12 children had food allergy and 20 children-drug allergy. The most frequent factors preceded dermatomyositis were respiratory diseases and inoculations. Assembling of genealogical anamnesis was made according to \"family portrait\". 14 families of children with dermatomyositis (369 relations in I-IV degree of relationship) were examined. Genealogical investigations revealed the high frequency of rheumatological pathology in proband's families. Small anomaly of development among probands (M +/- m = 12.5 +/- 0.6) exceeded these quantity comparing to the control group (n = 60). Dermatollphyics (98 indices on each child) contained a number of peculiarities for forming the group of risk. Onset of disease was acute or subacute in 2/3 of children. Primary chronic onset and the progress of the disease took place in 10 cases. An acute onset of dermatomyositis was characterized by fever, myaglia, arthralgia, bright skin symptoms: widespread purple violet face erythema, a \"butterfly wing\" or \"paraorbital glasses\", palmal erythema and widespread vascular manifestations on face, chest, back and limbs in the form of net--\"livedo reticularis\".</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"3-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13006762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum lipid concentrations in juvenile rheumatoid arthritis. 青少年类风湿性关节炎的血脂浓度。
Acta Universitatis Carolinae. Medica Pub Date : 1991-01-01
E Musiej-Nowakowska, F Zawadzka, H Wesołowska, M Mikołajew
{"title":"Serum lipid concentrations in juvenile rheumatoid arthritis.","authors":"E Musiej-Nowakowska,&nbsp;F Zawadzka,&nbsp;H Wesołowska,&nbsp;M Mikołajew","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Plasma lipid parameters were measured in 99 children with Juvenile Rheumatoid Arthritis and compared with a large age-matched healthy control group. All measurements were made in the same laboratory. Changes in cholesterol levels were found, some levels increased, some decreased. The triglyceride levels were significantly higher. Most marked changes in triglyceride level were observed in patients with changes in the kidneys and amyloidosis.</p>","PeriodicalId":75422,"journal":{"name":"Acta Universitatis Carolinae. Medica","volume":"37 1-2","pages":"46-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13006765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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