Behçet's syndrome with childhood onset.

Abstract

Behçet's syndrome is a multisystemic disease of vasculitic nature. Main symptoms consist of oral and genital ulceration, uveitis and skin lesions, mainly erythema nodosum. Other features may evolve: arthritis, thrombophlebitis, gastrointestinal, cardiovascular and neurologic lesions. The disease usually manifests in early adulthood, childhood onset is rare. There exists a male preponderance and a genetic disposition. The course of Behçet's syndrome in 5 patients with childhood onset is described.