Research on Chemical Intermediates最新文献

{"title":"Fe3O4@SiO2–Pr–THAM–(OSO3H)3: a novel magnetically separable catalyst for the synthesis of 4H-chromenes and their antioxidant and antibacterial study","authors":"Rutuja Ramesh Zond,&nbsp;Arati Subhash Kulkarni,&nbsp;Suvarna Raghunath Umape,&nbsp;Padma Babulal Dandge,&nbsp;Reshma Pandit Yadav,&nbsp;Nitin Maruti Naik,&nbsp;Vishal Hindurao Thorat,&nbsp;Prafulla Balkrishna Choudhari,&nbsp;Shankar Poshatti Hangirgekar,&nbsp;Sandeep Ashok Sankpal","doi":"10.1007/s11164-025-05506-7","DOIUrl":"10.1007/s11164-025-05506-7","url":null,"abstract":"<div><p>The present research delineates the synthesis and catalytic assessment of a novel Fe₃O₄@SiO₂–Pr–THAM–(OSO₃H)₃ magnetic nanoparticles. The structural conformation of as-prepared Fe₃O₄@SiO₂–Pr–THAM–(OSO₃H)₃ nanoparticles was evaluated using numerous analytical methods like Fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy, X-ray diffraction, transmission electron microscopy, vibrating sample magnetometry, thermogravimetric analysis. The catalytic potential of Fe₃O₄@SiO₂–Pr–THAM–(OSO₃H)₃ was tested for the syntheses of 4<i>H</i>-chromenes through one-pot condensation of 2-hydroxybenzaldehyde, cyclic 1,3-diketones, and 4-hydroxycoumarin in aqueous solution at 50 °C. The current methodology offers the benefits of superior catalytic activity, the utilization of environmentally friendly solvents, easy work-up procedure, excellent yield, magnetic separation, shorter reaction times, and catalyst reusability with no significant loss in potency after six cycles. The synthesized 4<i>H</i>-chromene derivatives were screened for antibacterial and in vitro antioxidant study and were found to have promising activities supported by molecular docking studies.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1233 - 1256"},"PeriodicalIF":2.8,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Narrow bandgap 1D g-C3N4/3D-Bi2MoO6 self-assembled heterojunction structure with enhanced photocatalytic performance for removal of MB or Cr (VI)","authors":"Zhizhong Qin,&nbsp;Chuande Liu,&nbsp;Jing Tan,&nbsp;Houxu Mei,&nbsp;Wen Xue,&nbsp;Wei Wei","doi":"10.1007/s11164-025-05503-w","DOIUrl":"10.1007/s11164-025-05503-w","url":null,"abstract":"<p>The wide bandgap structures and rapid carrier recombination are major factors limiting the photocatalytic activity of semiconductors. In this work, one dimension (1D) g-C₃N₄ with narrowed bandgap (1DCN) and three dimension (3D) Bi₂MoO₆ with inter-crossed nanosheet structure were combined into a heterojunction by a simple self-assembly method, which greatly improved the degradation efficiency of pollutants (methylene blue (MB) and Cr(VI)). The results showed that the degradation efficiency of MB by 1DCN/Bi₂MoO₆ could reach 97% after 210 min, and the reduction rate of Cr(VI) could reach more than 75% within 50 min under an illumination source of a 500W lamp source. The trapping analyses were performed and exhibited that the key reactive species in the 1DCN/Bi₂MoO₆ photodegradation were ·O₂⁻ and OH radicals in the reaction. In addition, the combined structure of 1D/3D effectively reduces the electron transport distance and increases the electron transfer rate, thereby further improving the catalytic effect of the heterojunction. The excellent catalytic activities of 1DCN/Bi₂MoO₆ have broad application prospects and provide reference for the combination of other heterostructures.</p>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1491 - 1510"},"PeriodicalIF":2.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction Note: Copper complex immobilized on Fe3O4 nanoparticles: a novel and recoverable heterogenous catalyst for synthesis of heterocycles","authors":"Jinfeng Fu,&nbsp;Xuemei Yang,&nbsp;Juan Du,&nbsp;Yan Hou,&nbsp;Zhongyang Liu,&nbsp;Jinwang Feng","doi":"10.1007/s11164-025-05511-w","DOIUrl":"10.1007/s11164-025-05511-w","url":null,"abstract":"","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1709 - 1710"},"PeriodicalIF":2.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of naphthalenone-thiazole hybrids for TNF-α, COX-2 inhibition and anti-oxidant capability","authors":"Jyoti Yadav,&nbsp;R. P. Chaudhary","doi":"10.1007/s11164-025-05513-8","DOIUrl":"10.1007/s11164-025-05513-8","url":null,"abstract":"<div><p>In this study, tetrahydronaphthalene carbothioamides <b>2</b>, characterized by spectroscopic methods and X-ray diffraction studies, were used to develop a series of novel tetrahydronaphthalenone-coupled thiazole derivatives <b>3</b>. The synthesized thiazole hybrids were evaluated for in-vitro anti-inflammatory activity against lipopolysaccharide (LPS)-induced inflammation in RAW264.7 macrophage cells. Notably, compound <b>3f</b> demonstrated the most potent anti-inflammatory effect by significantly reducing the expression of pro-inflammatory mediators, including nitric oxide species (IC₅₀ = 62.93 µM) and tumor necrosis factor-α (TNF-α) (67.50 µM). Additionally, <b>3f</b> inhibited cyclooxygenase-2 (COX-2) (IC₅₀ = 73.18 µM compared to celecoxib 41.21 µM) expression in a dose-dependent manner. The antioxidant activity of newly generated derivatives was also assessed using the DPPH assay, with compounds <b>3a</b>, <b>3b</b>, and <b>3c</b> showing the highest inhibition rates of 69.94%, 68.82%, and 64.77% at 100 µg/mL, respectively. Molecular docking studies targeting the active site of Human Peroxiredoxin 5 (PDB ID: 1HD2) and COX-2 (PDB ID: 4M11) were conducted to explore the potential interactions of these compounds with the receptor. Molecular dynamics (MD) simulation predicted the stability of the protein–ligand complex.</p></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1609 - 1640"},"PeriodicalIF":2.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanistic study of tetracycline removal and degradation in water using nCo@nZVI composite materials within a Fenton system","authors":"Shuxian Wei,&nbsp;Lanyue Zhang,&nbsp;Gang Du,&nbsp;Canhua Li,&nbsp;Chuan He,&nbsp;Minghui Li,&nbsp;Jiamao Li,&nbsp;Aiqin Mao,&nbsp;Yanran Wang","doi":"10.1007/s11164-025-05510-x","DOIUrl":"10.1007/s11164-025-05510-x","url":null,"abstract":"<div><p>In response to the escalating issue of antibiotic pollution in water bodies, with tetracycline (TC) serving as a representative example, this study introduced a novel magnetic nano cobalt @ nano zero valent iron (nCo@nZVI) composite material. To synthesize this material, the rheological phase reaction method was employed to produce sheet-like nZVI, followed by the liquid-phase reduction method to formulate the nCo@nZVI compound. Various advanced characterization techniques, including FESEM, HRTEM, EDS, XPS, XRD, BET, and FTIR, were utilized to systematically evaluate the physical, chemical properties, and structure of the material.Moreover, the study experimentally assessed the TC removal efficiency of nCo@nZVI, exploring the impacts of pH, temperature, and initial heavy metal ion concentration on this efficiency. It is worth noting that, under conditions of a neutral pH of 7, a temperature of 20 °C, and a material dosage of 1 g/L, the initial TC concentration of 20 mg/L in the wastewater was reduced to nearly zero (or completely removed) within 120 min. The adsorption kinetics and isotherm analysis revealed that the TC adsorption process by nCo@nZVI conforms to the pseudo-second-order kinetic model and Langmuir isotherm model, suggesting a predominantly chemical adsorption mechanism. The adsorption capacity derived from the Langmuir model was 25.33 mg/g.Further thermodynamic investigations demonstrated that the TC adsorption by nCo@nZVI is a spontaneous process. Additionally, the material primarily removes TC through an adsorption-degradation mechanism within the Fenton system. This eco-friendly and cost-effective material retains a removal rate of 65.87% after five cycles of regeneration treatment and can be recycled and reused under the influence of an external magnetic field, showcasing significant potential for the remediation of antibiotic-contaminated sites.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1555 - 1582"},"PeriodicalIF":2.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Achieving high yield production of p-methylbenzaldehyde from p-methylstyrene oxidation over Co-doped CeO2 micro-shuttles","authors":"Dongming Hu,&nbsp;Wanjing Wang,&nbsp;Tian Zhang,&nbsp;Xingyang Ji,&nbsp;Yuhang Chen,&nbsp;Panming Jian,&nbsp;Jiangyong Liu","doi":"10.1007/s11164-025-05512-9","DOIUrl":"10.1007/s11164-025-05512-9","url":null,"abstract":"<div><p>The present work introduces a simple strategy for the high yield production of <i>p</i>-methylbenzaldehyde (PMBA) from the selective oxidation of <i>p</i>-methylstyrene (PMS) under mild reaction conditions using Co-doped CeO₂ micro-shuttles. Impressively, a high PMBA yield of 70.1% is achieved, affording a PMS conversion of 93.7% and a selectivity of 74.8% to PMBA. The incorporation of Co into the CeO₂ framework triggers the local structure distortion and charge redistribution within the CeO₂ framework, contributing to the formation of weakened Ce–O bonds, coordinately unsaturated Ce³⁺ sites and oxygen vacancies (OVs). This assists in boosting the generation of active oxygen species for the oxidation of PMS to PMBA. The intrinsic merits of low cost, facile preparation and favorable catalytic performance endow the Co-doped CeO₂ micro-shuttles as a promising catalyst for the industrial production of PMBA from the selective oxidation of PMS.</p></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1329 - 1339"},"PeriodicalIF":2.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simple synthesis of V2O5/g–C3N4 photocatalyst for the oxidation of biomass-derived 5-hydroxymethylfurfural","authors":"Yao Lin,&nbsp;Danyao Huang,&nbsp;Chenyu Gong,&nbsp;Yingjie Zhou,&nbsp;Ying Wu","doi":"10.1007/s11164-024-05500-5","DOIUrl":"10.1007/s11164-024-05500-5","url":null,"abstract":"<div><p>It is highly important to effectively convert 5-hydroxymethylfurfural (5-HMF) into the high-value chemical 2,5-diformylfuran (DFF). In this study, graphitic carbon nitride (g–C₃N₄) and V₂O₅ were combined to construct the V₂O₅/g–C₃N₄ composites by a simple calcination method. The composite catalysts were comprehensively and thoroughly characterized. Moreover, the factors affecting the photocatalytic performance of the composite catalysts were systematically investigated. Compared with pure g–C₃N₄, the introduction of V₂O₅ can accelerate the transfer of photo-excited electrons while simultaneously inhibit the recombination of photo-generated carriers. Furthermore, radical trapping experiments deduced that photo-generated holes, ·O₂⁻ and ¹O₂ are the primary active species for the reaction system. Additionally, electron paramagnetic resonance experiments further confirmed that more active species can be generated on the surface of the V₂O₅/g–C₃N₄ catalyst. Under the synergistic effect of many advantages, the V₂O₅/g–C₃N₄ photocatalyst displayed superior photocatalytic performance in the photocatalytic oxidation of 5-HMF, with the highest 5-HMF conversion of 66.7% and DFF selectivity of 65.4%. Combined with the characterization results and the energy band positions, it was postulated that the V₂O₅/g–C₃N₄ photocatalyst worked following a Z-scheme mechanism.</p></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1473 - 1489"},"PeriodicalIF":2.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, characterization and catalytic assessment of novel hierarchical zeolite Hβ for the synthesis of biologically active amido alkyl naphthols","authors":"Bilal Mansuri,&nbsp;Aayushi Lodhi,&nbsp;Hemant Parmar,&nbsp;Ajay Dalai,&nbsp;Kalpana Maheria","doi":"10.1007/s11164-024-05484-2","DOIUrl":"10.1007/s11164-024-05484-2","url":null,"abstract":"<div><p>Hierarchization of conventional zeolites is recently seen as one of the promising strategies to overcome diffusional restrictions and make entry and exit of bulkier reactant/product entities easy and possible within the zeolite framework. In this work, an attempt has been made to synthesize novel hierarchical zeolite Hβ using filtrate of alkali-treated zeolite Hβ as precursor and its subsequent treatment with cationic surfactant, 6-bromo hexyl trimethylammonium bromide (6-Br-TMA). The resultant hierarchical zeolite is characterized by several techniques that include, low- and high-angle X-ray diffraction (LXRD and HXRD), Fourier-transformed infrared (FTIR) spectroscopy, solid-state NMR (²⁹Si, ²⁷Al, and ¹H) and NH₃-temperature programmed desorption (NH₃-TPD) studies. Their surface area has been determined by N₂ sorption isotherms studies. The acidity of hierarchical zeolite was measured by NH₃-TPD. The catalytic activity of hierarchical HZβ is compared with parent microporous Hβ catalyst toward synthesis of amido alkyl naphthols (AANs) and its derivatives via multicomponent reaction. Also, two novel derivatives 3,5-dibromo-4-hydroxy AAN and 2-ethoxy AAN has been synthesized using 3,5- dibromo-4-hydroxy benzaldehyde and 2-ethoxy benzaldehyde, respectively, as the substituents. AAN derivatives are medicinally significant chemical scaffolds and are well-known for their use in variety of nucleoside antibiotics, as well as HIV protease inhibitors like Ritonavir and Lopinavir. It is well-known for its Brady cardiac activity, antiviral, antibacterial, antifungal, and antiparasitic effects.</p><h3>Graphical abstract</h3><p>Mesozeolite HZβ catalyzed synthesis of biologically active AANs </p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1187 - 1212"},"PeriodicalIF":2.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing catalytic transfer semi-hydrogenation of alkynes over N-doped carbon-supported Pd–Ni bimetallic catalysts","authors":"Yanru Xiong,&nbsp;Weisai Qian,&nbsp;Junwen He,&nbsp;Lizhi Huang,&nbsp;Zezhe Wang,&nbsp;Weile Tan,&nbsp;Zhaofeng Chen,&nbsp;Ao Li,&nbsp;Haoquan Guo,&nbsp;Qinhong Wei","doi":"10.1007/s11164-025-05505-8","DOIUrl":"10.1007/s11164-025-05505-8","url":null,"abstract":"<div><p>Olefin is a crucial chemical intermediate that is in high demand for polymer production. The catalytic alkyne semi-hydrogenation process represents a promising avenue for industrial purification of olefins. Herein, we report the findings of a study investigating the transfer of alkyne semi-hydrogenation over a bimetallic catalyst, in which Pd nanoparticles and highly dispersed Ni atoms were anchored onto graphite-like C₃N₄ with nitrogen defects. The optimal Pd_0.14Ni_0.01 catalyst was used for intermolecular semi-hydrogenation of alkynes in conjunction with sodium borohydride. Nitrogen defects heightened the catalytic activity by modifying the electron density distribution and accelerating charge transfer from Pd to C₃N₄. Furthermore, the synergism of the Pd–Ni bimetallic positions facilitated the generation of the intermediate styrene and accelerated the rate-determining step. This study provides novel insights into the design of streamlined high-performance semi-hydrogenated catalysts.</p></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1371 - 1387"},"PeriodicalIF":2.8,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable waste stream catalysis in eco-friendly heterocyclization: an overview","authors":"U. P. Patil,&nbsp;S. U. Patil","doi":"10.1007/s11164-024-05495-z","DOIUrl":"10.1007/s11164-024-05495-z","url":null,"abstract":"<div><p>In recent inclination, waste-derived catalytic materials have gained a unique identity in the catalytic community due to their versatile properties. These catalytic systems can play a prominent role in the sustainable synthesis of functionalized heterocycles, as they are inexpensive alternatives while being an efficient, user-friendly material. The current review examines the preparation and applicability of waste-derived catalysts in heterocycle synthesis including Michael addition, Knoevenagel condensation, dehydrogenation, oxidation, oxidative dehydrogenation, and others. Moreover, the challenges, possible future development directions, and opportunities in synthesizing potent bioactive heterocycles over waste-derived catalytic materials are addressed. This review will galvanize further research to explore advanced catalysts developed from waste materials and their implications in heterocyclization.</p></div>","PeriodicalId":753,"journal":{"name":"Research on Chemical Intermediates","volume":"51 3","pages":"1151 - 1185"},"PeriodicalIF":2.8,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}