Vessel plus Pub Date : 2024-07-11 DOI: 10.20517/2574-1209.2023.140

Canqui Flores Bernabe, Romel P. Melgarejo-Bolivar, Alfredo Tumi-Figueroa, S. Thirukumaran, G. M. Devi, Sudhakar Sengan

{"title":"Echocardiographic cardiac views classification using whale optimization and weighted support vector machine","authors":"Canqui Flores Bernabe, Romel P. Melgarejo-Bolivar, Alfredo Tumi-Figueroa, S. Thirukumaran, G. M. Devi, Sudhakar Sengan","doi":"10.20517/2574-1209.2023.140","DOIUrl":"https://doi.org/10.20517/2574-1209.2023.140","url":null,"abstract":"Aim: A significant medical diagnostic tool for monitoring cardiovascular health and function is 2D electrocardiograms. For computerized echocardiogram (echo) analysis, recognizing how this device performs is essential. This paper primarily focuses on detecting the transducer's viewpoint in cardiac echo videos using spatiotemporal data. It distinguishes between different viewpoints by monitoring the heart's function and rate throughout the cycle of heartbeats. Computer-aided diagnosis (CAD) examination sizes are the first steps toward computerized classification of cardiac imaging tests. Since clinical analysis frequently starts with automatic classification, the current view can enhance the detection of Cardiac Vascular Disease (CVD).\u0000 Methods: This research article uses a Machine Learning (ML) algorithm called the Integrated Metaheuristic Technique (IMT), which is the Whale Optimization Algorithm with Weighted Support Vector Machine (WOA-WSVM).\u0000 Results: The parameters in the classification are optimized with the assistance of WOA, and the echo is classified using WSVM. The WOA-WSVM classifies the images effectively and achieves an accuracy of 98.4%.\u0000 Conclusion: The numerical analysis states that the WOA-WSVM technique outperforms the existing state-of-the-art algorithms.","PeriodicalId":75299,"journal":{"name":"Vessel plus","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141655563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of inflammation in the progression of diabetic kidney disease 炎症在糖尿病肾病进展中的作用

Vessel plus Pub Date : 2024-07-11 DOI: 10.20517/2574-1209.2024.21

Arunita Chatterjee, Jacqueline Tumarin, Sharma Prabhakar

{"title":"Role of inflammation in the progression of diabetic kidney disease","authors":"Arunita Chatterjee, Jacqueline Tumarin, Sharma Prabhakar","doi":"10.20517/2574-1209.2024.21","DOIUrl":"https://doi.org/10.20517/2574-1209.2024.21","url":null,"abstract":"Diabetic kidney disease (DKD) is a global health burden and the leading cause of end-stage renal disease. Its clinical management focuses on controlling hyperglycemia, hypertension, and hyperlipidemia. While the progression of DKD can be slowed with intervention, it cannot be stopped or reversed yet. The pathogenesis of DKD is complex, with an interplay of numerous signaling pathways, and research continues to decipher the players and their role, be it beneficial or pathogenic. Inflammation is an essential defense of our bodies against internal or external insults. The injuries that trigger inflammation range from pathogenic infections and wounds to dysregulated metabolism. Inflammation is helpful only if it is controlled and subsides after it has helped defend the individual against the insult. Uncontrolled or chronic inflammation is recognized as a contributor to numerous chronic diseases. Dysregulated inflammation plays a role in multiple aspects of DKD: glomerular hyperfiltration, mesangial expansion, podocyte injury, tubular injury, basement membrane thickening, fibrosis, and scarring. Since inflammation plays an integral role in the progression of DKD, targeting it for therapy is also reasonable. There is a growing trend of targeting inflammation as a therapeutic approach, with new targets being discovered and evaluated drugs every year. The exponential increase in literature necessitates a comprehensive summary of current information, hence this review.","PeriodicalId":75299,"journal":{"name":"Vessel plus","volume":"76 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141658076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of inflammation, oxidative stress, and deteriorated cognitive functions in patients after cardiac surgery 心脏手术后患者的炎症、氧化应激和认知功能退化之间的关系

Vessel plus Pub Date : 2024-07-11 DOI: 10.20517/2574-1209.2024.05

Gabriela Sabolová, L. Kočan, Miroslava Rabajdová, S. Rapčanová, Janka Vašková

引用次数: 0

Multivessel disease in patient with acute myocardial infarction: current treatment strategies and future perspectives 急性心肌梗死患者的多血管疾病：当前治疗策略与未来展望

Vessel plus Pub Date : 2024-05-23 DOI: 10.20517/2574-1209.2023.138

Antonella Tommasino, Federico Dell’Aquila, Vincenzo Cesario, Federica Tempestini, Matteo Casenghi, F. Giovannelli, Stefano Rigattieri, Emanuele Barbato, Andrea Berni

{"title":"Multivessel disease in patient with acute myocardial infarction: current treatment strategies and future perspectives","authors":"Antonella Tommasino, Federico Dell’Aquila, Vincenzo Cesario, Federica Tempestini, Matteo Casenghi, F. Giovannelli, Stefano Rigattieri, Emanuele Barbato, Andrea Berni","doi":"10.20517/2574-1209.2023.138","DOIUrl":"https://doi.org/10.20517/2574-1209.2023.138","url":null,"abstract":"Patients who present with acute myocardial infarction (AMI) often suffer from coronary multivessel disease (MVD). This condition is associated with an increased mortality rate; it is, therefore, important to improve clinical outcomes through appropriate treatment strategies. Over the past decades, extensive research in AMI and MVD patients has consistently shown that complete revascularization is superior to treatment of the only culprit lesion. Another controversial issue concerns the most appropriate timing for percutaneous coronary intervention in non-culprit lesions. Fractional flow reserve (FFR) is considered the best method for identifying ischemic coronary lesions in the context of acute coronary syndromes, but the detection of vulnerable plaques in non-culprit vessels could further improve clinical outcomes. Intravascular imaging goes beyond physiology and it is potentially useful to recognize patients who are vulnerable, despite negative FFR. Therefore, we analyzed the most relevant studies that have investigated the relationship between physiological indexes and plaque vulnerability. However, ongoing trials aim to clarify how coronary physiology can be combined with the benefits of intracoronary imaging.","PeriodicalId":75299,"journal":{"name":"Vessel plus","volume":"39 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141108020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial review: guidance for future atrial fibrillation research 编辑评论：未来心房颤动研究指南

Vessel plus Pub Date : 2024-05-20 DOI: 10.20517/2574-1209.2023.147

Thomas V. Bilfinge, G. H. Almassi, A. L. W. Shroyer

引用次数: 0

Selecting conduits for coronary artery bypass grafting: caution regarding the right internal mammary artery 选择冠状动脉旁路移植的导管：右乳内动脉的注意事项

Vessel plus Pub Date : 2024-04-25 DOI: 10.20517/2574-1209.2023.126

A. Browne, André Lamy

{"title":"Selecting conduits for coronary artery bypass grafting: caution regarding the right internal mammary artery","authors":"A. Browne, André Lamy","doi":"10.20517/2574-1209.2023.126","DOIUrl":"https://doi.org/10.20517/2574-1209.2023.126","url":null,"abstract":"This narrative review summarizes the angiographic and clinical outcome results of the most common coronary artery bypass grafting (CABG) conduits. The left internal mammary artery is the preferred first conduit to bypass the left anterior descending artery due to superior long-term survival and graft patency. Recent studies suggest the radial artery may be the preferred second conduit for the circumflex or right coronary artery territories, challenging the belief that the right internal mammary artery is the best choice. Despite their historical high failure rates, saphenous vein grafts continue to be widely used as secondary conduits. Several recent studies report suboptimal rates of right internal mammary artery graft failure, with clinical outcomes comparable to or worse than saphenous veins. The suboptimal rates of RIMA graft failure may be attributed to several factors such as improvements in vein graft failure rates, the use of in situ and non-left anterior descending artery grafting configurations, and skeletonized harvesting techniques. While observational studies favor multiple over single arterial grafting, randomized studies are needed for confirmation. The ongoing Randomized comparison of the clinical Outcome of single vs. Multiple Arterial grafts (ROMA) trial aims to determine if multiple arterial grafting reduces major adverse cardiovascular events and mortality and how secondary conduit selection influences these outcomes. Greater adoption of arterial grafting strategies is likely to come from high-quality evidence of benefit and safety from ongoing and future large pragmatic trials.","PeriodicalId":75299,"journal":{"name":"Vessel plus","volume":"19 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140653578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipid-lowering therapies in patients undergoing percutaneous coronary intervention 经皮冠状动脉介入治疗患者的降脂疗法

Vessel plus Pub Date : 2024-04-08 DOI: 10.20517/2574-1209.2023.135

Chan Joon Kim, Katherine Godfrey, Swagata Patnaik, Roxana Mehran

{"title":"Lipid-lowering therapies in patients undergoing percutaneous coronary intervention","authors":"Chan Joon Kim, Katherine Godfrey, Swagata Patnaik, Roxana Mehran","doi":"10.20517/2574-1209.2023.135","DOIUrl":"https://doi.org/10.20517/2574-1209.2023.135","url":null,"abstract":"Cardiovascular disease is the leading cause of death worldwide. Over past decades, multiple clinical trials have provided substantial evidence supporting the advantages of managing plasma lipids in individuals with coronary artery disease (CAD). A primary focus in reducing clinical atherosclerotic cardiovascular disease (ASCVD) in patients who have undergone percutaneous coronary intervention (PCI) is the regulation of blood lipids, with an emphasis on low-density lipoprotein (LDL) cholesterol. Statins represent the cornerstone of lipid-lowering therapy (LLT), with high-intensity statins consistently associated with beneficial outcomes in patients at high risk of ASCVD. Nevertheless, a notable portion of patients do not achieve their target cholesterol levels through statin monotherapy, necessitating the inclusion of complementary LLT strategies. Among these therapies are ezetimibe and proprotein convertase subtilisin/kexin type 9 inhibitors, which have also demonstrated clinical advantages by further reducing cholesterol levels. Existing guidelines recommend using these agents when maximally tolerated statin doses fall short of achieving target LDL levels. Additionally, recently introduced ATP-citrate lyase inhibitors, such as bempedoic acid, have gained approval as adjunctive treatments. Furthermore, icosapent ethyl, a purified derivative of eicosapentaenoic acid, targets hypertriglyceridemia and has shown cardiovascular benefits compared to placebo. In this article, we delve into the mechanisms of blood lipids and molecular targets in connection with CAD undergoing PCI. We also explore the current landscape of available LLT options, guidelines in practice, and the subtleties of therapy.","PeriodicalId":75299,"journal":{"name":"Vessel plus","volume":"138 S251","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140731583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abdominal involvement as a primary manifestation of systemic or isolated gastrointestinal vasculitis 以腹部受累为主要表现的全身性或孤立性胃肠道血管炎

Vessel plus Pub Date : 2024-03-29 DOI: 10.20517/2574-1209.2023.125

Gatr-alnada Gheriani, Petar S. Lenert

{"title":"Abdominal involvement as a primary manifestation of systemic or isolated gastrointestinal vasculitis","authors":"Gatr-alnada Gheriani, Petar S. Lenert","doi":"10.20517/2574-1209.2023.125","DOIUrl":"https://doi.org/10.20517/2574-1209.2023.125","url":null,"abstract":"Systemic vasculitides can cause a wide variety of gastrointestinal manifestations (GI) ranging from mild and frequently nonspecific abdominal pains to potentially life-threatening bowel perforations. Vascular involvement in systemic vasculitides can affect any GI blood vessel, most commonly mesenteric, hepatic, or splenic arteries. Inflammatory changes affecting different layers of arterial vessel walls can lead to aneurysmatic dilatation or blood vessel occlusion with subsequent organ ischemia leading to mucosal ulcerations, GI bleeding, perforations, or bowel obstruction. While the presence of extraintestinal manifestations may aid in diagnosis, delays in making appropriate diagnoses and rapid initiation of glucocorticoid and immunosuppressive treatment can have detrimental consequences. Awareness of isolated gastrointestinal vasculitis is of particular importance as it frequently remains undiagnosed until end-stage organ damage becomes apparent. Vasculitis mimics such as vascular Ehlers-Danlos syndrome or fibromuscular dysplasia add another lay of complexity in approaching patients with suspected GI vasculitis and should always be carefully considered.","PeriodicalId":75299,"journal":{"name":"Vessel plus","volume":"78 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140366564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct aortic cannulation, a safe alternative to femoral artery cannulation - 17 years of type A dissection surgery experience 主动脉直接插管，股动脉插管的安全替代方案 - 17 年 A 型夹层手术经验

Vessel plus Pub Date : 2024-03-21 DOI: 10.20517/2574-1209.2023.48

Tim Somers, Wilson W. L. Li, J. Jongenotter, Michel W. Verkroost, A. F. Verhagen, Wim J. Morshuis, Tim Smith, Guillaume S. C. Geuzebroek, R. Heijmen

{"title":"Direct aortic cannulation, a safe alternative to femoral artery cannulation - 17 years of type A dissection surgery experience","authors":"Tim Somers, Wilson W. L. Li, J. Jongenotter, Michel W. Verkroost, A. F. Verhagen, Wim J. Morshuis, Tim Smith, Guillaume S. C. Geuzebroek, R. Heijmen","doi":"10.20517/2574-1209.2023.48","DOIUrl":"https://doi.org/10.20517/2574-1209.2023.48","url":null,"abstract":"Aim: Optimal cannulation strategy for acute type A aortic dissection (ATAAD) surgery remains debated. Recent guidelines have advocated antegrade systemic perfusion through right axillary artery (RAX) cannulation, instead of femoral artery (FA) cannulation. However, RAX cannulation can be technically challenging and time-consuming. On the other hand, direct (ascending) aorta (DA) cannulation is a swift procedure that also ensures downstream antegrade flow. In this regard, we assessed whether DA cannulation is a safe alternative to FA cannulation.\u0000 Methods: Records of all patients undergoing ATAAD surgery between 2006-2022 at the Radboud University Medical Center were retrospectively reviewed.\u0000 Results: In total, 281 patients underwent surgery for ATAAD during the investigated period. Three patients were excluded due to death before the start of extracorporeal circulation and four because of RAX cannulation. Of the remaining 274 patients, 53% (N = 145) received primary FA and 47% (N = 129) DA cannulation, with a success rate of 98% for both approaches. Surgical mortality (combined in-hospital and 30-day) was 9.9% (7.8% DA group vs. 11.7% FA group, P = 0.271). New permanent neurological damage was seen in 10.9% vs. 6.9% (P = 0.248), respectively. In multivariate analysis, cannulation strategies were not significantly associated with surgical mortality nor postoperative new permanent neurological damage.\u0000 Conclusion: DA cannulation offers a safe and fast alternative to FA cannulation in ATAAD surgery. There were no significant differences in mortality and neurological complications. Future studies should focus on the differences between RAX and DA cannulation strategies on postoperative outcomes in ATAAD surgery.","PeriodicalId":75299,"journal":{"name":"Vessel plus","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140222229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is artificial intelligence the new kid on the block? Sustainable applications in cardiology 人工智能是否是新宠？心脏病学中的可持续应用

Vessel plus Pub Date : 2024-03-13 DOI: 10.20517/2574-1209.2023.123

A. Strangio, I. Leo, J. Sabatino, Margarita Brida, Chiara Siracusa, Nicole Carabetta, P. Zaffino, C. Critelli, Alessandro Laschera, M. Spadea, Daniele Torella, Pierre Sabouret, Salvatore De Rosa

引用次数: 0

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