Uirusu最新文献_第2页

[How viruses hitch a ride on pollen to infect plants]. [病毒如何搭上花粉感染植物]。

Uirusu Pub Date : 2025-01-01 DOI: 10.2222/jsv.75.111

Masamichi Isogai

{"title":"[How viruses hitch a ride on pollen to infect plants].","authors":"Masamichi Isogai","doi":"10.2222/jsv.75.111","DOIUrl":"https://doi.org/10.2222/jsv.75.111","url":null,"abstract":"Some plant viruses are transmitted to new host plants via pollen. However, since the first report of pollen transmission of plant viruses in 1918, the fundamental mechanisms underlying this process have remained unresolved. Pollen transmission of plant viruses is classified into two types: vertical transmission via pollen and horizontal transmission via pollen. Recently, we have obtained important insights into these mechanisms. In vertical transmission via pollen, it was suggested that when virus-infected pollen grains germinate, the pollen tubes deliver the sperm cells required for fertilization into the embryo sacs while simultaneously introducing the virus, resulting in the formation of virus-infected seeds. In contrast, in horizontal transmission via pollen, it was suggested that pollen tubes that have accumulated the virus penetrate and elongate within the stigma, establishing the initial virus infection sites. The infection then expanded into the vascular tissues of the stigma and style, and subsequently spread throughout the plant via the phloem. Thus, pollenborne viruses are thought to exploit the sexual reproduction system of seed plants, using pollen as a vector to achieve both horizontal and vertical transmission. In this review, we provide an overview of our research conducted to date on the transmission mechanisms of pollen-borne viruses.","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"75 2","pages":"111-120"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Nuclear Translocation of HTLV-1 bZIP Factor by Activation of the TGF-β/Smad Pathway: A Key Molecular Mechanism for HTLV-1 Oncogenesis]. [TGF-β/Smad通路激活HTLV-1 bZIP因子核易位：HTLV-1肿瘤发生的关键分子机制]。

Uirusu Pub Date : 2025-01-01 DOI: 10.2222/jsv.75.165

Takafumi Shichijo, Jun-Ichirou Yasunaga

引用次数: 0

[Measles virus]. 麻疹病毒。

Uirusu Pub Date : 2025-01-01 DOI: 10.2222/jsv.75.13

Fumio Seki, Makoto Takeda

{"title":"[Measles virus].","authors":"Fumio Seki, Makoto Takeda","doi":"10.2222/jsv.75.13","DOIUrl":"https://doi.org/10.2222/jsv.75.13","url":null,"abstract":"Measles virus is the pathogen that causes measles and is highly infectious. Measles virus uses two molecules as viral receptors: signaling lymphocytic activation molecule, expressed on immune cells, and nectin-4, expressed on epithelial cells. Usage of these receptors is strongly associated with the pathogenesis of measles. Although it remains a leading cause of childhood mortality worldwide, measles elimination is being promoted by the availability of a highly effective live attenuated vaccines. Due to the elimination of measles in many countries, the circulating measles genotypes have been reduced to two, B3 and D8, in recent years. Therefore, in addition to genotyping using the conventional 450-nucleotide N gene region, new methods such as wholegenome sequencing and analysis of the M-F non-coding region are being tested for case association and outbreak tracking. Although measles virus is a single serotype, there are genomic differences among genotypes, including variations in B-cell and T-cell epitopes. However, current live attenuated vaccines remain sufficiently effective against all genotypes. On the other hand, the maintenance of protective immunity in vaccinees may become increasingly important, since vaccine-induced immunity tends to wane over time unlike the more durable immunity following natural infection.","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"75 1","pages":"13-22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Structural analysis of Ebola virus nucleocapsid]. 埃博拉病毒核衣壳结构分析

Uirusu Pub Date : 2025-01-01 DOI: 10.2222/jsv.75.145

Shangfan Hu, Yoko Fujita-Fujiharu, Takeshi Noda

引用次数: 0

[The multidisciplinary study, "Aerosol virology/Aerovirology"-A new frontier]. [多学科研究，“气溶胶病毒学/航空病毒学”——新前沿]。

Uirusu Pub Date : 2025-01-01 DOI: 10.2222/jsv.75.121

Hidekazu Nishimura

引用次数: 0

[Effects of aging and inflammation on antigen-specific CD8+ T-cell responses that protect against severe disease following SARS-CoV-2 infection]. [衰老和炎症对SARS-CoV-2感染后抗原特异性CD8+ t细胞反应的影响]。

Uirusu Pub Date : 2025-01-01 DOI: 10.2222/jsv.75.47

Takuto Nogimori, Takuya Yamamoto

引用次数: 0

[SCARB2, one of the receptors for enterovirus A71, is not expressed on the cell surface.] 肠病毒A71的受体之一SCARB2不在细胞表面表达。

Uirusu Pub Date : 2024-01-01 DOI: 10.2222/jsv.74.153

Yorihiro Nishimura

引用次数: 0

[Development and Implementation of HPV Vaccination]. [发展和实施HPV疫苗接种]。

Uirusu Pub Date : 2024-01-01 DOI: 10.2222/jsv.74.9

Nagayasu Egawa

引用次数: 0

[Characterization of SARS-CoV-2 variants using mini-gut organoids]. [使用微型肠道类器官表征SARS-CoV-2变体]。

Uirusu Pub Date : 2024-01-01 DOI: 10.2222/jsv.74.45

Kei Miyakawa

引用次数: 0

[Elucidation of the molecular basis of negative-strand RNA virus genome replication]. [负链RNA病毒基因组复制分子基础的阐明]。

Uirusu Pub Date : 2024-01-01 DOI: 10.2222/jsv.74.67

Yusuke Matsumoto

{"title":"[Elucidation of the molecular basis of negative-strand RNA virus genome replication].","authors":"Yusuke Matsumoto","doi":"10.2222/jsv.74.67","DOIUrl":"https://doi.org/10.2222/jsv.74.67","url":null,"abstract":"The negative-strand RNA viruses are a group that includes many important pathogens. They share the common mechanism of genome replication and mRNA transcription. The viruses possess multifunctional RNA-dependent RNA polymerase that is responsible for all RNA synthesis activity, and the genome RNA is entirely covered with viral nucleoprotein. We aimed to understand these viruses in general by identifying the similarities and differences among each virus group. The viruses belonging to the family Paramyxoviridae in the order Mononegavirales is known to follow the \"Rule of Six\", which states that the number of nucleotides in the genome must be a multiple of six to be replicated. We have succeeded in generating a paramyxovirus that does not follow the Rule of Six and challenged to elucidate the significance of the Rule of Six using this recombinant virus. We also performed functional analysis of the promoter structure at the end of the genome of the viruses belonging to the order Bunyavirales and revealed unique features of RNA synthesis that differ from other segmented RNA viruses in the family Nairoviridae. Furthermore, we elucidated the unique mechanism of the Borna disease virus to establish persistent infection in the nucleus that is an exceptional property among RNA viruses.","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"74 1","pages":"67-76"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0