Turkish archives of pediatrics最新文献_第8页

Measuring Transition Readiness of Patients After Transfer from Pediatric to Adult Care in Rheumatology. 衡量风湿病患者从儿科转到成人科后的过渡准备情况。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-09-02 DOI: 10.5152/TurkArchPediatr.2024.24085

Ali Yağiz Ayla, Helin İdil Beşiroğlu, Feyza Nur Azman, Buğra Han Egeli, Hatice Eren, Sıla Öztürk, Sercan Ergün, Amra Adrovic, Kenan Barut, Fatih Haslak, Sezgin Şahin, Mehmet Yıldız, Huri Özdoğan, Özgür Kasapçopur, Serdal Ugurlu

{"title":"Measuring Transition Readiness of Patients After Transfer from Pediatric to Adult Care in Rheumatology.","authors":"Ali Yağiz Ayla, Helin İdil Beşiroğlu, Feyza Nur Azman, Buğra Han Egeli, Hatice Eren, Sıla Öztürk, Sercan Ergün, Amra Adrovic, Kenan Barut, Fatih Haslak, Sezgin Şahin, Mehmet Yıldız, Huri Özdoğan, Özgür Kasapçopur, Serdal Ugurlu","doi":"10.5152/TurkArchPediatr.2024.24085","DOIUrl":"https://doi.org/10.5152/TurkArchPediatr.2024.24085","url":null,"abstract":"Transitional care is essential to maintain the continuity of care in younger patients with rheumatic diseases. In this study, we aimed to assess the transition readiness of rheumatology patients who had already transferred from pediatric to adult care using a questionnaire. We included young adult rheumatology patients who had already transferred to adult rheumatology care. The Transition Readiness Assessment Questionnaire (TRAQ) was used in the adult rheumatology clinic to assess the patients' readiness; a retrospective chart review was conducted to include diagnosis, age at diagnosis, age at transfer, and current age. Three hundred and ten patients (184 female and 126 male) participated in this study. The mean age at diagnosis, the mean age at transfer, and the mean age at the time of the study were 10.7 ± 4.29, 21.1 ± 1.69, and 24.0 ± 2.26 years, respectively. Most of the patients had familial Mediterranean fever, followed by arthritis, connective tissue disorders, and other diseases. Tracking health issues was the lowest-scored domain. Females scored significantly higher than males in the tracking health issue domain (P = .006) and managing health issue domain (P = .028) but not in the overall TRAQ score (P = .053). Patients in different diagnosis and transfer age groups scored similarly across the domains. In this study, females performed better than males in 2 domains of the TRAQ questionnaire. Diagnoses or transfer age groups were not associated with TRAQ outcomes.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"59 5","pages":"501-505"},"PeriodicalIF":1.3,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Intravesical Tranexamic Acid for Severe Macroscopic Hematuria in a Biventricular Assist Device-Implanted Child. 使用膀胱内氨甲环酸治疗双室辅助装置植入患儿的严重镜下血尿

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-09-02 DOI: 10.5152/TurkArchPediatr.2024.24055

Eda Eyduran, Hamdi Cücan, Merve Havan, Tayfun Uçar, Ahmet Rüçhan Akar, Tanıl Kendirli

引用次数: 0

Research Trends on Self-Efficacy in Breastfeeding Mothers During 2000-2023: A Bibliometric Analysis. 2000-2023 年母乳喂养母亲自我效能感的研究趋势：文献计量分析。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-09-02 DOI: 10.5152/TurkArchPediatr.2024.24160

Ni Wayan Dian Ekayanthi, Besral Besral

{"title":"Research Trends on Self-Efficacy in Breastfeeding Mothers During 2000-2023: A Bibliometric Analysis.","authors":"Ni Wayan Dian Ekayanthi, Besral Besral","doi":"10.5152/TurkArchPediatr.2024.24160","DOIUrl":"https://doi.org/10.5152/TurkArchPediatr.2024.24160","url":null,"abstract":"Self-efficacy is important in supporting breastfeeding behaviors and enhancing breastfeeding practices. This study aimed to explore research trends, identify knowledge gaps, and provide a comprehensive overview of breastfeeding self-efficacy. Data were retrieved from the Scopus online database on March 20, 2024, encompassing articles published in English between 2000 and 2023. The search strategy focused on articles containing the keywords \"self-efficacy,\" \"breastfeeding,\" and \"mother.\" VOSviewer version 1.6.19 was then used to map the data and visually identify research clusters. The analysis yielded a significant increase in breastfeeding self-efficacy research over the past 2 decades. The United States led in publication numbers (117 documents), while Canada dominated citations (2792 citations). Furthermore, the analysis identified 8 critical themes in 8 different clusters, encompassing various aspects of breastfeeding, including determinants, behaviors, interventions, and mental health considerations during lactation, and employed research methodologies. One crucial gap identified in this study pertains to low breastfeeding social support. This includes a lack of support from peer groups, social networks, and social media platforms. Addressing this gap can be a valuable reference point for developing future interventions to bolster breastfeeding self-efficacy. Bibliometric analysis contributes to exploring research trends, identifying knowledge gaps, and providing a comprehensive overview of breastfeeding self-efficacy.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"59 5","pages":"440-448"},"PeriodicalIF":1.3,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respiratory Syncytial Virus Infections in Pediatric Intensive Care: Association of Sociodemographic Data and Clinical Outcomes with Viral and Bacterial Co-infections. 儿科重症监护中的呼吸道合胞病毒感染：社会人口学数据和临床结果与病毒和细菌合并感染的关联。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-09-02 DOI: 10.5152/TurkArchPediatr.2024.24149

Ülkem Koçoğlu Barlas, Nihal Akçay, Leyla Telhan, Murat Kanğın, Özge Umur, Agop Çıtak, Hazal Ceren Tuğrul, Seher Erdoğan, Mehmet Emin Menentoğlu, Esra Şevketoğlu, Muhterem Duyu, Kübra Boydağ Güvenç, Yaşar Yusuf Can, Batuhan Türkoğlu

{"title":"Respiratory Syncytial Virus Infections in Pediatric Intensive Care: Association of Sociodemographic Data and Clinical Outcomes with Viral and Bacterial Co-infections.","authors":"Ülkem Koçoğlu Barlas, Nihal Akçay, Leyla Telhan, Murat Kanğın, Özge Umur, Agop Çıtak, Hazal Ceren Tuğrul, Seher Erdoğan, Mehmet Emin Menentoğlu, Esra Şevketoğlu, Muhterem Duyu, Kübra Boydağ Güvenç, Yaşar Yusuf Can, Batuhan Türkoğlu","doi":"10.5152/TurkArchPediatr.2024.24149","DOIUrl":"https://doi.org/10.5152/TurkArchPediatr.2024.24149","url":null,"abstract":"The aim of the study was to evaluate respiratory syncytial virus (RSV) infections in cases followed in the pediatric intensive care unit (PICU). The study was designed as a prospective cohort in 6 PICUs. There were 3 groups: only RSV (+), RSV (v+) who were positive for another viral agent(s) in addition to RSV, and RSV (b+) who were positive for a bacterial agent(s) in addition to RSV. A total of 119 cases were included in the study, 67 (56.3%) of whom were male. The RSV (+) group had a lower pH compared to the other groups and a higher rate of acute bronc hiolitis/bronchitis diagnoses compared to the RSV (v+) group. The RSV (v+) group had higher bicarbonate levels, higher creatinine levels, longer hospital stays, and higher Pediatric Risk of Mortality-3 scores (PRISM-3) compared to the RSV (+) group. Cases with RSV (b+) were younger and also had lower body weight compared to the other groups. Furthermore, the RSV (b+) group had higher C-reactive protein and Procalcitonin (PCT) levels and higher rates of High Flow Nasal Cannula-Oxygen Therapy (HFNC-OT) use. Multiple linear regression analysis revealed that PRISM-3 score, PCT levels, Pediatric Acute Respiratory Distress Syndrome diagnoses, inhaled steroid use, chronic illness status, and heart rate on admission were associated with the length of stay in the PICU. High flow nasal cannula-oxygen therapy continues to be the most frequently preferred respiratory support method in RSV infections. Viral infections accompanying RSV can increase the severity of the disease.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"59 5","pages":"494-500"},"PeriodicalIF":1.3,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical and Prognostic Characteristics in Childhood Osteosarcoma: A Single-Center Experience in Türkiye. 儿童骨肉瘤的临床和预后特征：土耳其单中心经验。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-09-02 DOI: 10.5152/TurkArchPediatr.2024.24043

Mert Altıntaş, Emel Cabi Ünal, Nurdan Taçyıldız, Sonay İncesoy Özdemir, Handan Uğur Dinçaslan

{"title":"Clinical and Prognostic Characteristics in Childhood Osteosarcoma: A Single-Center Experience in Türkiye.","authors":"Mert Altıntaş, Emel Cabi Ünal, Nurdan Taçyıldız, Sonay İncesoy Özdemir, Handan Uğur Dinçaslan","doi":"10.5152/TurkArchPediatr.2024.24043","DOIUrl":"https://doi.org/10.5152/TurkArchPediatr.2024.24043","url":null,"abstract":"In our study, we aimed to share the clinical experiences of our center regarding osteosarcoma cases, the most common primary malignant bone tumor in children and adolescents. With approval from the Clinical Research Ethics Committee of our center, the data of 59 pediatric patients who were followed up in our center with the diagnosis of osteosarcoma between 2007 and 2021 were evaluated retrospectively. The mean time between the onset of symptoms and diagnosis was 3 months. Although not statistically significant, patients with a diagnostic delay of 3 months or less had a higher rate of recurrence and mortality. 59.3% of patients had metastatic disease, and the presence of metastases was associated with higher rates of recurrence and mortality. Significant number of patients had multiple surgical operations. Amputation as the first operation and the need for multiple surgeries were associated with higher mortality. Pathologically poor response to chemotherapy is associated with mortality. 42.4% of patients died, and the 5-year overall and disease-free survival rates were 47.5% and 30.5%, respectively. Survival rates were highest in non-metastatic and non-relapsed patients, and lowest in metastatic patients and patients with poor response to chemotherapy. Renal problems and cardiotoxicity were most frequently treatment-related complications. Significant improvements have been achieved in the survival and quality of life in osteosarcoma cases compared to previous years; however, there is still a long way to go, and more multicenter and multidisciplinary studies are needed on osteosarcoma.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"59 5","pages":"461-468"},"PeriodicalIF":1.3,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Outcomes of Oral Antibiotic Switch in Children with Staphylococcus aureus Bacteremia. 金黄色葡萄球菌菌血症患儿改用口服抗生素的临床效果

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-09-02 DOI: 10.5152/TurkArchPediatr.2024.24108

Salih Demirhan, Brenda I Anosike

{"title":"Clinical Outcomes of Oral Antibiotic Switch in Children with Staphylococcus aureus Bacteremia.","authors":"Salih Demirhan, Brenda I Anosike","doi":"10.5152/TurkArchPediatr.2024.24108","DOIUrl":"https://doi.org/10.5152/TurkArchPediatr.2024.24108","url":null,"abstract":"Staphylococcus aureus is one of the leading causes of bacteremia in children. In this study, we aimed to evaluate our center's experience on the etiology, management, and outcomes of pediatric Staphylococcus aureus bacteremia (SAB) with particular focus on transitioning to oral antibiotic therapy. This retrospective cohort study included children aged ≤ 19 years diagnosed with SAB over a 5-year period. The main outcome was poor clinical outcome related to SAB defined as (1) recurrence of SAB within 30 days after discontinuation of SAB treatment and (2) any-cause mortality within 30 days after detection of SAB. Over a 5-year period, 88 SAB episodes of 76 unique patients were included. The most common source of SAB attributed to central line (n = 34), followed by osteoarticular (n = 24), infections. All patients received at least one day of intravenous (IV) antibiotics and treatment was switched to an oral agent in 45.5% of SAB episodes. Sources of SAB in the oral switch group were osteoarticular (n = 21), skin and soft tissue (n = 7), central line (n = 3), thrombophlebitis (n = 2), head and neck infection (n = 1), and unknown (n = 6). 30-day mortality and SAB recurrence within 30 days after initial treatment completion occurred in 3 and 5 SAB episodes, respectively. None of the patients in oral switch group had poor clinical outcomes. Our study results indicate that 30-day any-cause mortality and SAB-related mortality is low in children. Similar to growing adult literature, oral switch in SAB treatment was not associated with poor SAB outcomes in selected patients.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"59 5","pages":"469-475"},"PeriodicalIF":1.3,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Therapeutic Potential of Vitamin D in Kawasaki Disease and Its Interplay with the COVID-19 探索维生素 D 在川崎病中的治疗潜力及其与 COVID-19 的相互作用

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-09-02 DOI: 10.5152/TurkArchPediatr.2024.24141

Visuddho Visuddho, Yongki Welliam, Fan Maitri Aldian, Mahendra Tri Arif Sampurna, Abyan Irzaldy

{"title":"Exploring the Therapeutic Potential of Vitamin D in Kawasaki Disease and Its Interplay with the COVID-19","authors":"Visuddho Visuddho, Yongki Welliam, Fan Maitri Aldian, Mahendra Tri Arif Sampurna, Abyan Irzaldy","doi":"10.5152/TurkArchPediatr.2024.24141","DOIUrl":"https://doi.org/10.5152/TurkArchPediatr.2024.24141","url":null,"abstract":"Several studies have reported outbreaks of Kawasaki disease among children amid the coronavirus disease 2019 (COVID-19) pandemic. Vitamin D possesses high utility in modulating the immune system to repair and prevent severe inflammation in COVID-19. This study aims to explore the association between Kawasaki disease and vitamin D levels in pediatric patients and describe the potential role of vitamin D in promoting recovery and preventing complications associated with Kawasaki disease in pediatric patients with COVID-19. The association between Kawasaki disease and vitamin D was explored adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, utilizing databases such as PubMed, Google Scholar, and ScienceDirect. The association between COVID-19 and Kawasaki disease was also assessed by reviewing relevant literature.Most studies indicated that patients with Kawasaki disease had lower vitamin D levels. Vitamin D supplementation was also found to be deficient in the pediatric population with Kawasaki disease. Inflammation of the endothelium, cytokine storms, and endothelial dysfunction in patients suffering from COVID-19 may contribute to the development of Kawasaki disease. Vitamin D is believed to have protective potential for Kawasaki disease outcomes by modulating the inflammatory response. Administering vitamin D to pediatric patients with viral infections like COVID-19 is expected to accelerate clinical improvement and prevent complications from Kawasaki disease.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"59 5","pages":"432-439"},"PeriodicalIF":1.3,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastrointestinal Stromal Tumor: A Rare Tumor of Childhood. 胃肠道间质瘤：一种罕见的儿童肿瘤。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24041

Bekir Erdeve, Nevzat Aykut Bayrak, Ecmel Kaygusuz, Aslı Turgutoğlu Yılmaz, Serdar Moralıoğlu

引用次数: 0

The Coronavirus Disease 2019 Pandemic and Time to Diagnosis for Childhood Pulmonary Diseases: Outcomes of a Tertiary Care Center. 2019年冠状病毒疾病大流行与儿童肺部疾病的诊断时间：一家三级医疗中心的成果。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.23158

Meltem Akgül Erdal, Halime Nayır Büyükşahin, İsmail Güzelkaş, Birce Sunman, Didem Alboğa, Nagehan Emiralioğlu, Ebru Yalçın, Deniz Doğru, H Uğur Özçelik, Nural Kiper

{"title":"The Coronavirus Disease 2019 Pandemic and Time to Diagnosis for Childhood Pulmonary Diseases: Outcomes of a Tertiary Care Center.","authors":"Meltem Akgül Erdal, Halime Nayır Büyükşahin, İsmail Güzelkaş, Birce Sunman, Didem Alboğa, Nagehan Emiralioğlu, Ebru Yalçın, Deniz Doğru, H Uğur Özçelik, Nural Kiper","doi":"10.5152/TurkArchPediatr.2024.23158","DOIUrl":"10.5152/TurkArchPediatr.2024.23158","url":null,"abstract":"Coronavirus disease 2019 pandemic caused many changes in the social behaviors of individuals and the provision of health systems. Many studies revealed reductions in the number of diagnoses and delays in diagnosis time during the pandemic. This study aimed to evaluate the effect of the pandemic on the time to diagnosis of major diseases of pediatric pulmonology. Newly diagnosed patients with cystic fibrosis (CF), childhood interstitial lung disease (chILD), tuberculosis (TB), and primary ciliary dyskinesia (PCD) were grouped into pandemic (group 1) and 2 consecutive pre-pandemic periods divided into equal intervals (groups 2 and 3). For each disease group, the time to diagnosis was compared between the specified periods. A total number of patients were 171 in this study. In the CF group, there was no statistically difference in time to diagnosis between periods. In the chILD group, there was a statistically significant difference in time to diagnosis (P = .036) between groups (group 1: 2 months, group 2: 4 months and group 3: 10.5 months) that was not originated from pandemic period. In TB group there was no statistically significant difference between groups. In the PCD group, the impact of the pandemic on the time to diagnosis could not be clarified because the time interval to diagnosis (minimum: 2 years, maximum: 16 years) exceeded the studied periods (21 months). In our study, no effect found between the pandemic and age at diagnosis or time to diagnosis in patients with PCD, chILD, CF, and TB at our center.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"59 4","pages":"370-374"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting Childhood-Onset Systemic Lupus Erythematosus. 重温童年发病的系统性红斑狼疮

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24097

Pınar Özge Avar-Aydın, Hermine I Brunner

{"title":"Revisiting Childhood-Onset Systemic Lupus Erythematosus.","authors":"Pınar Özge Avar-Aydın, Hermine I Brunner","doi":"10.5152/TurkArchPediatr.2024.24097","DOIUrl":"10.5152/TurkArchPediatr.2024.24097","url":null,"abstract":"Childhood-onset systemic lupus erythematosus (cSLE) is a chronic autoimmune disease with a multisystemic involvement diagnosed during childhood. The disease is marked by the production of autoantibodies targeting self-antigens, often before symptoms emerge. The presentation, clinical course, and outcome vary significantly among patients with cSLE. The onset of cSLE can be at any age during childhood while a diagnosis of cSLE before the age of 5 years is rare and raises a suspicion of monogenic lupus. Childhood-onset systemic lupus erythematosus affects various organs and systems, most frequently presenting with mucocutaneous, musculoskeletal, renal, and neuropsychiatric manifestations. Multiple disease flares can be seen during the disease course. Childhood-onset systemic lupus erythematosus causes significant morbidity and mortality. Children and adolescents with cSLE show higher disease activity and damage, and more aggressive immunosuppressive treatments are needed compared to adultonset SLE. Early diagnosis can be difficult due to the insidious onset with nonspecific symptoms. Disease activity and damage measures aim to ensure an accurate evaluation of disease status. A multidisciplinary approach and individualized disease management are important. Disease management is complex including the control of disease activity, the reduction of flares and damage, and a limitation of drug toxicity while improving the health-related quality of life in patients with cSLE.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"59 4","pages":"336-344"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141895055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0