Turkish archives of pediatrics最新文献

Gastrointestinal Stromal Tumor: A Rare Tumor of Childhood. 胃肠道间质瘤：一种罕见的儿童肿瘤。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24041

Bekir Erdeve, Nevzat Aykut Bayrak, Ecmel Kaygusuz, Aslı Turgutoğlu Yılmaz, Serdar Moralıoğlu

引用次数: 0

The Coronavirus Disease 2019 Pandemic and Time to Diagnosis for Childhood Pulmonary Diseases: Outcomes of a Tertiary Care Center. 2019年冠状病毒疾病大流行与儿童肺部疾病的诊断时间：一家三级医疗中心的成果。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.23158

Meltem Akgül Erdal, Halime Nayır Büyükşahin, İsmail Güzelkaş, Birce Sunman, Didem Alboğa, Nagehan Emiralioğlu, Ebru Yalçın, Deniz Doğru, H Uğur Özçelik, Nural Kiper

{"title":"The Coronavirus Disease 2019 Pandemic and Time to Diagnosis for Childhood Pulmonary Diseases: Outcomes of a Tertiary Care Center.","authors":"Meltem Akgül Erdal, Halime Nayır Büyükşahin, İsmail Güzelkaş, Birce Sunman, Didem Alboğa, Nagehan Emiralioğlu, Ebru Yalçın, Deniz Doğru, H Uğur Özçelik, Nural Kiper","doi":"10.5152/TurkArchPediatr.2024.23158","DOIUrl":"10.5152/TurkArchPediatr.2024.23158","url":null,"abstract":"Coronavirus disease 2019 pandemic caused many changes in the social behaviors of individuals and the provision of health systems. Many studies revealed reductions in the number of diagnoses and delays in diagnosis time during the pandemic. This study aimed to evaluate the effect of the pandemic on the time to diagnosis of major diseases of pediatric pulmonology. Newly diagnosed patients with cystic fibrosis (CF), childhood interstitial lung disease (chILD), tuberculosis (TB), and primary ciliary dyskinesia (PCD) were grouped into pandemic (group 1) and 2 consecutive pre-pandemic periods divided into equal intervals (groups 2 and 3). For each disease group, the time to diagnosis was compared between the specified periods. A total number of patients were 171 in this study. In the CF group, there was no statistically difference in time to diagnosis between periods. In the chILD group, there was a statistically significant difference in time to diagnosis (P = .036) between groups (group 1: 2 months, group 2: 4 months and group 3: 10.5 months) that was not originated from pandemic period. In TB group there was no statistically significant difference between groups. In the PCD group, the impact of the pandemic on the time to diagnosis could not be clarified because the time interval to diagnosis (minimum: 2 years, maximum: 16 years) exceeded the studied periods (21 months). In our study, no effect found between the pandemic and age at diagnosis or time to diagnosis in patients with PCD, chILD, CF, and TB at our center.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fostering Tomorrow: Uniting Artificial Intelligence and Social Pediatrics for Comprehensive Child Well-being. 培育明天：将人工智能与社会儿科学相结合，促进儿童的全面福祉。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24076

Murat Gülşen, Sıddıka Songül Yalçın

{"title":"Fostering Tomorrow: Uniting Artificial Intelligence and Social Pediatrics for Comprehensive Child Well-being.","authors":"Murat Gülşen, Sıddıka Songül Yalçın","doi":"10.5152/TurkArchPediatr.2024.24076","DOIUrl":"10.5152/TurkArchPediatr.2024.24076","url":null,"abstract":"This comprehensive review explores the integration of artificial intelligence (AI) in the field of social pediatrics, emphasizing its potential to revolutionize child healthcare. Social pediatrics, a specialized branch within the discipline, focuses on the significant influence of societal, environmental, and economic factors on children's health and development. This field adopts a holistic approach, integrating medical, psychological, and environmental considerations. This review aims to explore the potential of AI in revolutionizing child healthcare from social pediatrics perspective. To achieve that, we explored AI applications in preventive care, growth monitoring, nutritional guidance, environmental risk factor prediction, and early detection of child abuse. The findings highlight AI's significant contributions in various areas of social pediatrics. Artificial intelligence's proficiency in handling large datasets is shown to enhance diagnostic processes, personalize treatments, and improve overall healthcare management. Notable advancements are observed in preventive care, growth monitoring, nutritional counseling, predicting environmental risks, and early child abuse detection. We find that integrating AI into social pediatric healthcare aims to enhance the effectiveness, accessibility, and equity of pediatric health services. This integration ensures high-quality care for every child, regardless of their social background. The study elucidates AI's multifaceted applications in social pediatrics, including natural language processing, machine learning algorithms for health outcome predictions, and AI-driven tools for health and environmental monitoring, collectively fostering a more efficient, informed, and responsive pediatric healthcare system.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141899146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting Childhood-Onset Systemic Lupus Erythematosus. 重温童年发病的系统性红斑狼疮

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24097

Pınar Özge Avar-Aydın, Hermine I Brunner

{"title":"Revisiting Childhood-Onset Systemic Lupus Erythematosus.","authors":"Pınar Özge Avar-Aydın, Hermine I Brunner","doi":"10.5152/TurkArchPediatr.2024.24097","DOIUrl":"10.5152/TurkArchPediatr.2024.24097","url":null,"abstract":"Childhood-onset systemic lupus erythematosus (cSLE) is a chronic autoimmune disease with a multisystemic involvement diagnosed during childhood. The disease is marked by the production of autoantibodies targeting self-antigens, often before symptoms emerge. The presentation, clinical course, and outcome vary significantly among patients with cSLE. The onset of cSLE can be at any age during childhood while a diagnosis of cSLE before the age of 5 years is rare and raises a suspicion of monogenic lupus. Childhood-onset systemic lupus erythematosus affects various organs and systems, most frequently presenting with mucocutaneous, musculoskeletal, renal, and neuropsychiatric manifestations. Multiple disease flares can be seen during the disease course. Childhood-onset systemic lupus erythematosus causes significant morbidity and mortality. Children and adolescents with cSLE show higher disease activity and damage, and more aggressive immunosuppressive treatments are needed compared to adultonset SLE. Early diagnosis can be difficult due to the insidious onset with nonspecific symptoms. Disease activity and damage measures aim to ensure an accurate evaluation of disease status. A multidisciplinary approach and individualized disease management are important. Disease management is complex including the control of disease activity, the reduction of flares and damage, and a limitation of drug toxicity while improving the health-related quality of life in patients with cSLE.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141895055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Trace Element Levels and Toxic Metals in Obese Children: A Single-Center Experienc. 调查肥胖儿童体内的微量元素水平和有毒金属：单中心经验

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24016

Sultan Kaba, Sinan Kılıç

{"title":"Investigation of Trace Element Levels and Toxic Metals in Obese Children: A Single-Center Experienc.","authors":"Sultan Kaba, Sinan Kılıç","doi":"10.5152/TurkArchPediatr.2024.24016","DOIUrl":"10.5152/TurkArchPediatr.2024.24016","url":null,"abstract":"The complete role of factors contributing to the pathogenesis of childhood obesity remains to be fully elucidated. Limited research has addressed trace elements in the context of child obesity. Our objective was to assess trace element and lead (Pb), copper (Cu) (are toxic metal) levels in both healthy and obese children, and to investigate the potential correlations between these elements and obesity-related anthropometric measurements, lipid profiles, as well as insulin and glucose levels. Furnace atomic absorption spectrophotometry was employed to measure the concentrations of trace elements in the serum. Additionally, fasting glucose, insulin, and lipid levels were determined in obese children (body mass index ≥ 95th percentile for age and sex), along with 50 healthy children. Only the obesity group underwent an oral glucose tolerance test (OGTT). Significantly reduced levels of Fe, Mg, Zn, and Co were observed in obese children, whereas Cu, Pb, and Mn levels were elevated (P < .001, P <.001, P = .002, P = .008, P <.001, P = .001, P = .007, respectively). Significant positive correlations were found between the 2-hour glucose level in OGTT and Mn (P = .013), as well as between peak insulin and insulin levels at the 30th and 60th minutes, and Fe (P = .001, P = .025, P = .001). This study indicates that an imbalance in trace element levels and the accumulation of Pb may be associated with obesity, while levels of Mn and Fe may be linked to glucose intolerance.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Life-Threatening Recurrence of Paroxysmal Cold Hemoglobinuria in a Child During Influenza A Infection. 一名儿童在感染甲型流感期间再次出现危及生命的阵发性冷性血红蛋白尿。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24067

İbrahim Cemal Maslak, Muhammed Burak Selver, Ömer Kaşkaya, Merve Bayrak Yıldırım, Ayşe Çiğdem Sivrice, Mahmut Keskin, Ebru Sagay, Ebru Yılmaz Keskin

引用次数: 0

Factors Associated with Post-rewarming Procalcitonin Levels in Newborns with Hypoxic Ischemic Encephalopathy. 缺氧缺血性脑病新生儿退热后降钙素原水平的相关因素

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.24089

Aslı Okbay Güneş, Aydın Bozkaya, Mehmet Emin Avlanmış

{"title":"Factors Associated with Post-rewarming Procalcitonin Levels in Newborns with Hypoxic Ischemic Encephalopathy.","authors":"Aslı Okbay Güneş, Aydın Bozkaya, Mehmet Emin Avlanmış","doi":"10.5152/TurkArchPediatr.2024.24089","DOIUrl":"10.5152/TurkArchPediatr.2024.24089","url":null,"abstract":"To determine the factors associated with the procalcitonin levels in newborns with hypoxic-ischemic encephalopathy (HIE) who received therapeutic hypothermia (TH). The neonates, who had moderate/severe HIE and were treated with TH, were included. The neonates were arranged into 2 groups by procalcitonin (PCT) level after rewarming was completed. The neonates who had a procalcitonin level of < 2.5 ng/ml constituted Group 1 and the ones who had a procalcitonin level of ≥ 2.5 ng/ml constituted Group 2. Univariate and multivariate logistic regression was used to assess the factors related with PCT level. The first group included 123 (87.9%) neonates and the second group included 17 (12.1%) neonates. The median gestational age was 38 (36-39) weeks and the mean birth weight was 3081.7 ± 552.8 grams. In group 2, the rates for severe HIE, cesarean section, antibiotic switch, convulsion, inotrope use and mortality were higher, and duration of hospitalization was longer, whereas Apgar scores were lower (P < .05). The risk of a high procalcitonin level was found to be 6-fold (95% CI 1.9-19.1) higher in severe HIE and 5.2-fold higher (95% CI 1.7-16) in cesarean delivery. In neonates with HIE/TH, high post-rewarming procalcitonin levels were related with severe HIE and cesarean delivery. Some other clinical and laboratory findings, which may reflect worse clinical status, were also associated with high procalcitonin levels.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Clinical Presentations and Disease Severity of Children Hospitalized with Influenza A and B. 甲型和乙型流感住院儿童临床表现和疾病严重程度的比较

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.23286

Aykut Ekşi, Gökçen Kartal Öztürk, Candan Çiçek, Figen Gülen, Esen Demir

{"title":"Comparison of Clinical Presentations and Disease Severity of Children Hospitalized with Influenza A and B.","authors":"Aykut Ekşi, Gökçen Kartal Öztürk, Candan Çiçek, Figen Gülen, Esen Demir","doi":"10.5152/TurkArchPediatr.2024.23286","DOIUrl":"10.5152/TurkArchPediatr.2024.23286","url":null,"abstract":"This study compared the clinical presentations and disease severity between influenza A and B (FLUA and FLUB). The study included children hospitalized with virologically confirmed influenza between 2010 and 2020. The severity of the disease was evaluated based on admission to the pediatric intensive care unit (PICU), mechanical ventilation requirement, length of hospital stay, length of stay in the PICU, and death. Influenza viruses were compared within predefined age groups (0-2, 3-9, and 10-18 years) and in all age groups. Of 343 patients, FLUA and FLUB were detected in 75.8% and 24.2% of children, respectively. FLUB was associated with a higher incidence of headache and abdominal pain (P < .001 and P = .01). Children with FLUB were prescribed antibiotics and antivirals 0.56 and 0.58- fold fewer than those with FLUA. Headache and abdominal pain rates were higher in patients between 3 and 9 years with FLUB. Children between 0 and 2 years with FLUA were more frequently admitted to the PICU than those with FLUB (23.6% vs. 4.0%; P < .004). Eight patients with FLUA died, while only 1 with FLUB died (P = .69). The clinical presentation of FLUA and FLUB appeared similar, except for headache and abdominal pain, which were more prevalent in older patients with FLUB. Our study revealed that children between 0 and 2 years with FLUA were at a significantly higher risk for admission to the PICU. As a result, greater attention and awareness should be paid to children under 2 years old with FLUA.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Through the Glass Ceiling: The Quest for Gender Equality in Academia. 穿越玻璃天花板：学术界对性别平等的追求》。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.28624

Tanyel Zubarioğlu

引用次数: 0

The Correlation of Fluid Creep with Fluid and Electrolyte Imbalance In Pediatric Intensive Care Unit Dr. Cipto Mangunkusumo National Central Public Hospital. 儿科重症监护室液体蠕变与体液和电解质失衡的相关性 Cipto Mangunkusumo 博士，国立中央公立医院。

IF 1.3

Turkish archives of pediatrics Pub Date : 2024-07-01 DOI: 10.5152/TurkArchPediatr.2024.23309

Irene Yuniar, Jojor Sihotang, Regina Suriadi, Devina June

{"title":"The Correlation of Fluid Creep with Fluid and Electrolyte Imbalance In Pediatric Intensive Care Unit Dr. Cipto Mangunkusumo National Central Public Hospital.","authors":"Irene Yuniar, Jojor Sihotang, Regina Suriadi, Devina June","doi":"10.5152/TurkArchPediatr.2024.23309","DOIUrl":"10.5152/TurkArchPediatr.2024.23309","url":null,"abstract":"Fluid creep, used as a drug diluent can contribute to fluid and electrolyte balance. Fluid creep brings substantial volume and electrolyte load to patients, especially in critically ill children. This study is conducted to evaluate the correlation of fluid creep with fluid and electrolyte balance in critically ill children. This cross-sectional study was conducted in a single tertiary center. We include children aged 1 month- 18 years in the pediatric intensive care unit (PICU). Exclusion criteria were patients receiving renal replacement therapy and plasmapheresis. Fluids and electrolyte intake were recorded at admission and the first 24 hours in the PICU. A total of 64 patients were observed. The sources of fluid intake are 61% from parenteral, 25% from enteral nutrition, and 12% from fluid creep. There were significant correlations between the volume (r = 0.304, P = .015) and electrolyte intake (r = 0.742, P = .035) of fluid creep with daily fluid balance. There is no correlation between fluid creep and electrolyte changes in 24 hours. Fifty-two patients used WFI (81.2%) as a drug diluent. Our study showed that fluid creep constitutes 12% of daily fluid intake. There is a correlation between the volume and electrolyte intake from fluid creep to daily fluid balance, so it is important to include the volume of fluid creep in calculating the fluid balance. Thus, it is recommended to use hypotonic fluid like WFI compared to NaCl 0.9% for drug diluent.","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0