{"title":"Evaluating the Humoral Immune Response to Sinovac-Coronavac in a Pediatric Patient with Propionic Acidemia: A Case Study.","authors":"İlayda Ergün, Harika Öykü Dinç, Nihan Burtecene, Ertuğrul Kıykım, Çiğdem Aktuğlu-Zeybek, Mehmet Şerif Cansever, Ayça Kıykım, Bekir Kocazeybek, Tanyel Zubarioglu","doi":"10.5152/TurkArchPediatr.2025.25082","DOIUrl":"https://doi.org/10.5152/TurkArchPediatr.2025.25082","url":null,"abstract":"","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 4","pages":"440-442"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Child Deaths in Pediatric Intensive Care Unit: Unveiling Preventable Risks and Urging Awareness.","authors":"Banu Katlan, İsmail Kızıldağ, Özlem Kahraman Çayan, Mesut Topdemir, Ümit Korkmaz","doi":"10.5152/TurkArchPediatr.2025.25098","DOIUrl":"10.5152/TurkArchPediatr.2025.25098","url":null,"abstract":"<p><p>Objective: Child mortality remains a global public health concern and a key indicator of societal development. Despite advances in healthcare, many children-especially in low- and middle-income countries-continue to die from preventable causes. Pediatric intensive care units (PICUs), which provide critical care and continuous monitoring, offer a unique opportunity to systematically analyze preventable child deaths and identify areas for intervention. This study aims to identify preventable causes of death in a tertiary PICU and highlight systemic and clinical factors contributing to these outcomes. It seeks to raise awareness and guide quality improvement efforts to reduce avoidable pediatric mortality. Materials and Methods: This descriptive study included patients admitted to the PICU of Mersin City Training and Research Hospital between April 2022 and August 2024. Included patients were previously healthy, aged 1 month to 18 years, and died due to preventable causes. Demographic, clinical, and cause-specific data were analyzed using SPSS. Results: Of 3038 PICU admissions, 207 children died, and 47 (23%) of these deaths were determined to be preventable. The leading cause was traffic accidents (n=15, 32%), followed by home accidents (n = 10,21%), vaccine-preventable diseases (n= 7, 15%), suicides (n = 5, 11%), and drownings (n=5, 11%). Conclusion: Nearly 1 in 4 deaths in the PICU were preventable. These results emphasize the importance of implementing targeted preventive strategies, such as public education, environmental safety improvements, and early health interventions, to reduce avoidable pediatric mortality.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 4","pages":"404-411"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric Acute Respiratory Distress Syndrome Updates in the Light of the PALICC-2 Guidelines.","authors":"Dincer Yildizdas, Nagehan Aslan","doi":"10.5152/TurkArchPediatr.2025.24331","DOIUrl":"10.5152/TurkArchPediatr.2025.24331","url":null,"abstract":"<p><p>Acute respiratory distress syndrome (ARDS) was first described in adults. However, the risk factors for the development of ARDS, etiological causes, and the pathophysiology of the disease, as well as morbidity and mortality, are not the same in children and adults. Since adult definitions were used for many years and the definition of pediatric ARDS was not clear within these definitions, this situation caused the prevalence of pediatric ARDS to be underestimated. For the reasons stated above, the pediatric ARDS (PARDS) definition, which is made considering only children and is used today, was made by \"The Pediatric Acute Lung Injury Consensus Conference (PALICC) Group\" in 2015, and new updates were published in the PALICC-2 guideline in 2023. The aim of this review is to summarize the diagnostic and treatment approaches of PARDS according to the PALICC-2 guideline recommendations.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 4","pages":"362-371"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What is the Difference Between the Different Types of Thermometers?","authors":"Mahmood Dhahir Al-Mendalawi","doi":"10.5152/TurkArchPediatr.2025.25007","DOIUrl":"10.5152/TurkArchPediatr.2025.25007","url":null,"abstract":"","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 4","pages":"448"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Akif Dündar, Sedanur Tekin Can, Başak Nur Akyıldız
{"title":"Evaluating Trauma Scores for Mortality Prediction in Pediatric Patients.","authors":"Mehmet Akif Dündar, Sedanur Tekin Can, Başak Nur Akyıldız","doi":"10.5152/TurkArchPediatr.2025.25040","DOIUrl":"10.5152/TurkArchPediatr.2025.25040","url":null,"abstract":"<p><p>Objective: This study aimed to evaluate the effectiveness of various trauma scoring systems in predicting mortality in pediatric patients with multiple trauma and to determine their cut-off values. Materials and Methods: A methodological study was conducted on pediatric patients under 18 years of age admitted to the pediatric intensive care unit for multiple trauma. Demographic data, clinical parameters, and trauma scores, including the Revised Trauma Score (RTS), Pediatric Trauma Score (PTS), Glasgow Coma Scale (GCS), Abbreviated Injury Scale (AIS), Injury Severity Score (ISS), Pediatric Risk of Mortality Score III (PRISM-3), and Pediatric Logistic Organ Dysfunction (PELOD-2), were collected and analyzed. Results: Among the 107 patients, there were 15 deaths (14%). Significant differences were observed between survivors and non-survivors in all trauma scores. Non-survivors had higher AIS, ISS, PRISM-3, and PELOD-2 scores, while survivors had higher PTS, RTS, and GCS scores (P < .001). In the multivariate binary logistic regression analysis, both ISS (odds ratio [OR] 1.060 [95% CI: 1.029-1.092], P < .001) and RTS (OR 0.059 [95% CI: 0.007-0.517], P =.011) were independently associated with mortality. Injury Severity Score demonstrated the highest area under the curve (AUC) value of 0.98 in the receiver operating characteristic (ROC) analysis. Conclusion: Both ISS and RTS were identified as independent predictors of mortality in pediatric trauma patients. Injury Severity Score was the strongest predictor, while RTS also provided significant prognostic value. Integration of these scores into early assessment may enhance risk stratification and support clinical decision-making in pediatric trauma care.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 4","pages":"391-397"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathological Scores for Depression, Anxiety, and Stress and Their Association with Social Support in Mothers by Employment Status.","authors":"Beril Aydın, Melda Çelik, Esma Altınel Açoğlu, Emel Isıyel, Sıddika Songül Yalçın","doi":"10.5152/TurkArchPediatr.2025.24206","DOIUrl":"10.5152/TurkArchPediatr.2025.24206","url":null,"abstract":"<p><p>Objective: Social support is a crucial factor that can offer both preventive and protective benefits against mental problems in mothers. This study investigated the associations between social support and depression, anxiety, and stress disorders in Turkish mothers with young children. Materials and Methods: A cross-sectional survey, comprising 27 questions and the \"Depression, Anxiety, and Stress Scale (DASS-21),\" was administered to mothers with children between the ages of 2-6 years. Results: Among the 542 participating mothers, 56.5% were employed, 62.2% reported receiving social support, and 53.7% of the children attended nursery or kindergarten. The percentage of participants with high depression scores (>9) was 3.9%, high anxiety scores (>7) was 9.6%, and high stress scores (>14) was 4.1%. Overall, the prevalence of abnormal Depression, Anxiety, and Stress Scale-21 (DASS-21) scores was 11.8%. Multivariate logistic regression analysis revealed that housewives had higher odds of having abnormal DASS-21 scores. Additionally, working mothers without social support and those without access to nursery care had significantly higher rates of abnormal DASS-21 scores. Conclusion: The study emphasizes the importance of social support in improving maternal mental health, particularly for working mothers. Providing adequate social support and access to childcare can enhance maternal well-being, reduce stress, and improve self-efficacy in managing caregiving responsibilities. Future research should focus on developing policies and interventions that strengthen social support networks and improve childcare options to address mental health concerns among mothers.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 4","pages":"384-390"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Strengthening Neonatal Respiratory Support in Low-Resource Settings: Lessons from Maternal and Child Health Project in the Gambia.","authors":"Ömer Erdeve, Tanıl Kendirli, Necdet Ünüvar","doi":"10.5152/TurkArchPediatr.2025.25069","DOIUrl":"10.5152/TurkArchPediatr.2025.25069","url":null,"abstract":"","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 4","pages":"438-439"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Achievement and Features Associated with Childhood Definition of Remission in Juvenile-Onset Systemic Lupus Erythematosus.","authors":"Hakan Kisaoglu, Ozge Baba, Mukaddes Kalyoncu","doi":"10.5152/TurkArchPediatr.2025.25092","DOIUrl":"10.5152/TurkArchPediatr.2025.25092","url":null,"abstract":"<p><p>Objective: To identify the feasibility of achieving the childhood definition of remission, investigate factors affecting achievement and determine the concordance rate with adult definition in children with systemic lupus erythematosus (SLE). Materials and Methods: Medical records of children diagnosed with SLE between 2012 and 2022 were reviewed. The Definitions of Remission in Systemic Lupus Erythematosus (DORIS) definition of remission was used as the adult definition of remission, and a lower glucocorticoid threshold, as proposed, was used for children weighing <50 kg. Cox regression analysis was performed to identify features associated with remission. Results: Among the 50 included patients, 35 (70%) achieved the adult definition of remission in a median of 16 months. While 33 (66%) patients achieved the childhood definition of remission, 25 (76%) achieved both definitions concomitantly. A lower rate of damage (15.2% vs. 52.9%, P= .008) and flare count (median 1 vs. 2, P=.001) were observed in patients with remission despite significantly longer follow-up duration (median 59 months vs. 32 months, P=.007). Survival analysis revealed that the presence of positive anti-dsDNA antibodies (hazard ratio [HR], 0.47; P=.035) and immunosuppressive usage (HR: 0.45, P =.032) were associated with a higher risk of not achieving remission. Conclusion: Childhood definition of remission is achievable in two-thirds of children with SLE and displays substantial concordance with the adult definition. Additionally, the higher risk of failure to achieve remission in children using immunosuppressants reflects a milder course in a subgroup of children who achieved remission and signifies the need for more efficacious treatment modalities for severe manifestations.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 4","pages":"398-403"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}