Ghasem Miri-Aliabad, Ali Khajeh, Zeinab Nasri-Nasrabadi
{"title":"X-Linked Thrombocytopenia in a 6-Year-Old Boy.","authors":"Ghasem Miri-Aliabad, Ali Khajeh, Zeinab Nasri-Nasrabadi","doi":"10.5152/TurkArchPediatr.2025.24269","DOIUrl":"10.5152/TurkArchPediatr.2025.24269","url":null,"abstract":"","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"560-561"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gül Trabzon, Osman Fırat Çalışkan, Servet Yüce, Ufuk Utku Güllü
{"title":"The Overlooked Factor: Iron Deficiency Anemia in Children with Obesity.","authors":"Gül Trabzon, Osman Fırat Çalışkan, Servet Yüce, Ufuk Utku Güllü","doi":"10.5152/TurkArchPediatr.2025.25116","DOIUrl":"10.5152/TurkArchPediatr.2025.25116","url":null,"abstract":"<p><p>Objective: Childhood obesity is a growing public health concern associated with a wide range of metabolic and hematologic disturbances. Among these, iron deficiency anemia (IDA) may be underrecognized. This study aimed to compare hematologic and biochemical profiles between children with obesity and healthy peers. Materials and Methods: In this retrospective study, 84 children with obesity were compared with 101 age- and sex-matched healthy controls. Anthropometric and laboratory parameters-including hemoglobin(HGB), mean corpuscular volume (MCV), red cell distribution width (RDW), serum iron, total iron-binding capacity (TIBC), ferritin, and vitamin B12-were analyzed between groups. Results: Children with obesity demonstrated a higher frequency of anemia, with low HGB observed in 22.6% compared to 10.9% in controls (P = .031). Microcytosis, indicated by decreased MCV, was more prevalent in the obesity group (53.6% vs. 32.7%, P = .004), as was elevated RDW (40.5% vs. 18.8%, P = .001). Median serum iron levels were significantly lower (51 vs. 66 µg/dL, P < .001), and TIBC was higher (330 vs. 299 µg/dL, P = .002) in children with obesity. Ferritin levels showed no significant difference between groups (23.7 vs. 18.3 ng/mL, P = 0.101). ALT levels were also elevated in the obesity group (30 vs. 18 U/L, P = .001). Conclusion: The prevalence of IDA and related hematologic abnormalities is higher among children with obesity compared to healthy peers. These findings highlight the value of routine hematologic screening in pediatric obesity management to enable early detection and appropriate clinical intervention.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"469-473"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Children at the Apex of a Fraying Triangle: Disasters and Recent Policies Disrupting the Human-Nature-Animal Harmony.","authors":"Ayşe Çiğdem Aktuğlu Zeybek","doi":"10.5152/TurkArchPediatr.2025.1112255","DOIUrl":"10.5152/TurkArchPediatr.2025.1112255","url":null,"abstract":"","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"450-452"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of the 2022 American Academy of Pediatrics Hyperbilirubinemia Guideline on Hospitalization Rates and Short-Term Outcomes: A Single-Center Study.","authors":"Ferhan Demirtaş, Büşra Kütükçü, Yasemin Ezgi Köstekçi, Emel Okulu, Ömer Erdeve, Begüm Atasay, Saadet Arsan","doi":"10.5152/TurkArchPediatr.2025.25164","DOIUrl":"10.5152/TurkArchPediatr.2025.25164","url":null,"abstract":"<p><p>Objective: This study aimed to evaluate the impact of the revised 2022 American Academy of Pediatrics (AAP) guideline for hyperbilirubinemia on hospitalization rates and short-term outcomes. Materials and Methods: This retrospective observational study compared 2 periods, before (period 1: January 1-August 31, 2022) and after (period 2: September 1-December 31, 2022) implementation of the AAP 2022 guideline in a tertiary neonatal unit. Neonates born at ≥35 weeks' gestational age who met phototherapy criteria were included. In period 2, infants who would have been hospitalized under the previous 2004 guideline but not under the new one were followed to assess the need for hospitalization and the occurrence of neurotoxicity. Results: The rate of hospitalization due to hyperbilirubinemia decreased from 23% (n = 95/409) in period 1 to 14% (n = 25/173) in period 2 (P = .017). When the new guideline was retrospectively applied, it was found that 58% (n = 55) of previously hospitalized patients in period 1 would not have required admission under the new criteria. In period 2, 37 neonates met the previous criteria, but only 25 were hospitalized under the new guideline; 2 of the 25 required rehospitalization. The remaining 12 newborns were followed as outpatients without developing neurotoxicity. Overall, 51% (n = 67) of newborns who met previous criteria did not meet the new hospitalization thresholds. Conclusion: The implementation of the AAP 2022 guideline was associated with a reduced risk of hospitalization without an increased risk of bilirubin-related neurotoxicity. Structured followup and individualized risk assessment remain essential for safe outpatient management.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"531-535"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Pediatric Cardiomyopathy Patients in Pediatric Intensive Care Unit.","authors":"Şeyda Kesen, Merve Havan, Mehmet Ramoğlu, Tayfun Uçar, Ercan Tutar, Tanıl Kendirli","doi":"10.5152/TurkArchPediatr.2025.25111","DOIUrl":"10.5152/TurkArchPediatr.2025.25111","url":null,"abstract":"<p><p>Objective: Cardiomyopathies (CMP) are an important cause of end-stage heart failure in childhood. The study aims to evaluate the clinical features, treatments, and outcomes of the patients diagnosed with CMP followed in the pediatric intensive care unit (PICU). Materials and Methods: This retrospective study was conducted using the data of the patients followed in the PICU between January 1, 2008, and December 31, 2019. Demographic information of the patients, CMP types, informations of echocardiography and angiography, findings upon admission to the PICU, medical treatments applied, respiratory and circulatory support, cardiac transplantation status, and results were examined. Results: A total of 76 patients hospitalized with the diagnosis of CMP were included in the study. Among them, 39 (51%) patients were female. The majority (68.4%) were diagnosed with dilated CMP. The remaining patients were diagnosed with noncompaction left ventricular (LV) dilated CMP (14.5%), restrictive CMP (10.5%), hypertrophic CMP (5.3%), and noncompaction LV restrictive CMP (1.3%). Diuretics, inotropes, and invasive mechanical ventilation were used in 90.8%, 93.4%, and 75% of patients, respectively. While 43.4% (n = 33) of the patients needed extracorporeal membrane oxygenation (ECMO) support during their PICU hospitalization, 15.8% (n = 12) received LV assist device (LVAD) and 2.6% (n = 2) biventricular assist device (BiVAD) support. Heart transplantation was performed in 10 patients (13.2%). Finally, 40 (52.6%) of the patients died. Conclusion: Pediatric patients with CMP with severe heart failure require inotropes, mechanical ventilation, ECMO, LVAD, BiVAD, and heart transplantation, which are crucial for lifesaving measures, along with intensive care follow-up.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"515-523"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akif Kavgacı, Betül Erdoğdu, Serdar Kula, İpek Bozkurt
{"title":"Cross-Sectional Analysis of Echocardiography Reports in Light of Guideline Recommendations.","authors":"Akif Kavgacı, Betül Erdoğdu, Serdar Kula, İpek Bozkurt","doi":"10.5152/TurkArchPediatr.2025.25123","DOIUrl":"10.5152/TurkArchPediatr.2025.25123","url":null,"abstract":"<p><p>Objective: The aim of this study is to identify discrepancies in pediatric echocardiography reports across centers and emphasize the significance of establishing a standardized reporting approach. Materials and Methods: In this study, pediatric echocardiography reports from various institutions (university hospitals [UHs], training and research hospitals [TRHs], and private healthcare facilities) (33 reports from 29 centers) were evaluated for adherence to key criteria outlined in consensus guidelines by the European Association of Cardiovascular Imaging of the European Society of Cardiology and the Association for European Paediatric and Congenital Cardiology. Each echocardiography report was systematically categorized into distinct sections, including patient information, medical records, echocardiographic findings, and conclusions. Results: Systemic and pulmonary venous return was reported in 58.3% of cases from UHs, 77.7% from TRHs, and 66.7% from private healthcare institutions (PHIs). Pulmonary artery and aortic arch were documented in 83.3% of reports from PHIs, 88.8% from TRHs, and 25% from UHs. Coronary artery dimensions and course were reported in 58.3% of reports from UHs, 77.7% from TRHs, and 16.7% from PHIs. Physician interpretations and diagnoses were present in all reports. However, information regarding environmental factors, such as whether the patient was awake or agitated during the examination, was reported in 66.6% of cases from TRHs but was entirely absent in reports from other institutions. Conclusion: This study demonstrates important variability in pediatric echocardiography reports. Adopting international guidelines may facilitate standardized reporting, ensure consideration of underassessed parameters, and promote a unified terminology across institutions.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"500-506"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Fifth Vital Sign in the First 1000 Days: Early Relational Health.","authors":"İclal Ayrancı Sucaklı, Sıddika Songül Yalçın","doi":"10.5152/TurkArchPediatr.2025.24317","DOIUrl":"10.5152/TurkArchPediatr.2025.24317","url":null,"abstract":"<p><p>Early childhood development forms the cornerstone for a healthy, fulfilling, and productive life. Research in health psychology and longevity highlights that social relationships are the most significant determinant of lifelong health and development. Among these, early attachment between children and caregivers, bolstered by positive experiences and nurturing environments, is pivotal for optimal growth, development, and well-being. This highlights the need for holistic approaches in healthcare, particularly during the critical first 1000 days of life. To address these needs, comprehensive evaluations must include assessments of childcaregiver interactions alongside biological, psychological, social, and environmental factors. Recognizing this, the American Academy of Pediatrics has embraced the Early Relational Health (ERH) framework, focusing on fostering healthy relationships during this crucial period. The framework encompasses all caregivers, including parents, extended family, and peers. The ERH framework emphasizes a broad assessment of factors affecting health-biological, psychological, interactional, economic, and environmental-within the child and caregivers' living contexts. The primary objective is not to teach parenting skills but to cultivate safe, stable, nurturing relationships supporting lifelong well-being. The ERH underscores the critical importance of assessing relational health as a \"fifth vital sign,\" alongside traditional measures such as respiratory rate, heart rate, temperature, and blood pressure, in the first 1000 days. Integrating this framework into health systems can enhance the well-being of children and caregivers, ensuring a robust foundation for lifelong development.</p>","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"453-461"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RE: Comment On: Pediatric Urinary Stone Disease: A 10-Year SingleCenter Experience from Türkiye.","authors":"Utku Dönger","doi":"10.5152/TurkArchPediatr.2025.250302","DOIUrl":"10.5152/TurkArchPediatr.2025.250302","url":null,"abstract":"","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"566-567"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gulay Aksak Yigit, Gamze Sonmez, Kubra Deveci, Ilke Kılıc Topcu, Hacer Neslihan Bildik, Mehmet Ayvaz, Diclehan Orhan, Deniz Cagdas
{"title":"Osteomyelitis with a Pathologic Fracture, Mortal Liver Abscess, and Cholelithiasis: Distinct Features in two Families with the Same p47-phox Mutation.","authors":"Gulay Aksak Yigit, Gamze Sonmez, Kubra Deveci, Ilke Kılıc Topcu, Hacer Neslihan Bildik, Mehmet Ayvaz, Diclehan Orhan, Deniz Cagdas","doi":"10.5152/TurkArchPediatr.2025.24231","DOIUrl":"10.5152/TurkArchPediatr.2025.24231","url":null,"abstract":"","PeriodicalId":75267,"journal":{"name":"Turkish archives of pediatrics","volume":"60 5","pages":"552-556"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}