Translational sports medicine最新文献

{"title":"Cognitive Function among Young Women’s Football Players in the Summer Heat","authors":"Soichi Ando, Nana Ogoh, Shotaro Saito, Hironori Watanabe, Maki Ohsuga, Tetsuya Hasegawa, Shigehiko Ogoh","doi":"10.1155/2023/5516439","DOIUrl":"https://doi.org/10.1155/2023/5516439","url":null,"abstract":"Recently, there has been a growing focus on studies related to women’s football. However, the cognitive function of female football players has not been extensively characterized. Thus, we explored how the cognitive function of female football players was altered during a series of matches in summer and examined day-to-day variations in cognitive function with regard to dehydration status. Resting cognitive function was assessed from 17 young women football players during the Japan Club Youth Women’s football tournament, which spanned eight consecutive days. Cognitive function initially improved, with this improvement sustained throughout the tournament. It is worth noting that ten participants experienced symptoms of dehydration at least once during the tournament; however, these symptoms were not found to be linked to impaired cognitive function, suggesting that resting cognitive function remains unaffected during summer matches, even in the presence of dehydration symptoms.","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135972744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemodynamic Response in Ascending Aorta Surgery Patients during Moderate Intensity Resistance Training","authors":"Rikke Gottlieb, Kasper Arnskov, Marius Henriksen, Eva Prescott, Hanne Rasmusen, Christian Have Dall","doi":"10.1155/2023/7616007","DOIUrl":"https://doi.org/10.1155/2023/7616007","url":null,"abstract":"Background. In patients undergoing ascending aortic surgery (AAS), postsurgical physical exercise with a safe and effective exercise prescription is recommended. Resistance training is associated with blood pressure (BP) elevations that may increase the risk of new aortic dissection or rupture. However, the acute hemodynamic response to resistance training for this patient group is unknown. Aim. The aim of this study was to investigate peak systolic BP (SBP) increases in AAS patients during moderate intensity resistance training. Methods. SBP was measured continuously beat-to-beat with a noninvasive method during three sets of leg presses at moderate intensity. A 15-repetition maximum strength test was performed to estimate the maximal amount of resistance a participant could manage 15 times consecutively (equivalent to approximately 60–65% of their maximum strength). Results. The study had 48 participants in total, i.e., 24 cases and 24 controls. Both groups consisted of 10 females (42%) and 14 males (58%). The case group had a mean age of 60.0 (SD ± 11.9) years and a mean of 16.3 months since surgery (minimum 4.4 and maximum 39.6 months). 22 of the 24 cases received antihypertensive medication. The median baseline BP was 119/74 mmHg among cases and 120/73 mmHg among controls. During the first set of leg presses, the median peak SBP was 152 mmHg, in the second set 154 mmHg, and in the third set 165 mmHg. Corresponding values in controls were 170 mmHg, 181 mmHg, and 179 mmHg. The highest peak SBP registered in an AAS patient was 190 mmHg and in any healthy control was 287 mmHg. Conclusion. The findings indicate that AAS patients in control of their BP have the endurance to perform 3 sets of resistance training at moderate intensity as their SBP increases with a maximum of 39% from the baseline compared to the 51% increase in the control group.","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136232953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra-Tester and Inter-Tester Reliability of the Lachmeter When Measuring Knee Joint Laxity.","authors":"Mikkel Oxfeldt, Anton B Pedersen, Mette Hansen","doi":"10.1155/2023/5583949","DOIUrl":"10.1155/2023/5583949","url":null,"abstract":"<p><p>Knee injuries are common among all age groups, and clinical knee examination is essential for the prognosis, follow-up, and rehabilitation process. The Lachmeter is a newly developed digitized modification of the Rolimeter, making it easier and faster for the test personnel to read the test result. In the present study, we aimed to evaluate the intra-tester and inter-tester reliability of the Lachmeter when testing healthy and traumatic knees. 24 healthy participants and a smaller sample of six ACL patients were examined with the Lachmeter by two intermediate testers and re-examined on a second visit within 21 days. All measurements were performed using two different grip techniques: a Lachman grip and an anterior drawer grip. Intra- and inter-tester reliability was evaluated using intra-class correlation coefficient (ICC), standard error of measurement (SEM), smallest detectable change (SDC), Student's paired <i>t</i>-test, and Bland-Altman plots. The results showed in healthy subjects poor to good intra-tester reliability (ICC range: -0.28-0.87, SEM range: 0.33-1.14 mm, and SDC range: 0.91-3.17 mm) and inter-tester reliability (ICC range: 0.41-0.87, SEM range: 0.27-0.67 mm, and SDC range: 0.75-1.87 mm). In ACL patients, intra-tester reliability was moderate to excellent (ICC range: 0.53-0.94, SEM range: 0.14-0.88 mm, and SDC range: 0.38-2.44 mm), with the exception of one measurement (ICC: 0.26 95% CI [-3.43; 0.89]), whereas inter-tester reliability was overall good (ICC range: 0.61-0.89, SEM range: 0.29-0.71 mm, and SDC range: 0.79-1.97 mm). Reliability measures between grip techniques indicated that the Lachman grip was more reliable than the anterior drawer grip. In conclusion, the Lachmeter showed variation between reliability measures, ranging from poor to good in healthy subjects and moderate to excellent in ACL patients. Future studies are needed to validate the Lachmeter against a gold-standard knee laxity assessment.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11022768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49305115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Traditional and Advanced Resistance Training Paradigms on Muscle Hypertrophy in Trained Individuals: A Systematic Review and Meta-Analysis.","authors":"Pedro A B Fonseca, Bernardo N Ide, Dustin J Oranchuk, Moacir Marocolo, Mário A M Simim, Michael D Roberts, Gustavo R Mota","doi":"10.1155/2023/9507977","DOIUrl":"10.1155/2023/9507977","url":null,"abstract":"<p><p>Trained individuals may require variations in training stimuli and advanced resistance training paradigms (ADV) to increase skeletal muscle hypertrophy. However, no meta-analysis has examined how ADV versus traditional (TRAD) approaches may differentially affect hypertrophic outcomes in trained populations. The aim of this review was to determine whether the skeletal muscle hypertrophy responses induced by TRAD differed from ADV in resistance-trained individuals. Furthermore, we sought to examine potential effects of dietary factors, participants' training status, and training loads. We searched for peer-reviewed, randomized controlled trials (published in English) conducted in healthy resistance-trained adults performing a period of TRAD and ADV with pre-to-post measurement(s) of muscle hypertrophy in PubMed, Web of Science, SPORTDiscus, and MEDLINE databases up to October 2022. A formal meta-analysis was conducted in Revman5, and risk of bias was assessed by ROB2. Ten studies met the inclusion criteria. Results indicated no difference between ADV and TRAD for muscle thickness (SMD = 0.05, 95% CI: -0.20 0.29, <i>p</i> = 0.70), lean mass (SMD = -0.01, 95% CI: -0.26 0.23, <i>p</i> = 0.92), muscle cross-sectional area (SMD = -0.07, 95% CI: -0.36 0.22, <i>p</i> = 0.64), or all measurements analyzed together (SMD = -0.00, 95% CI: -0.15 0.14, <i>p</i> = 0.95). No heterogeneity or inconsistencies were observed; however, unclear risk of bias was present in most of the studies. Short-term ADV does not induce superior skeletal muscle hypertrophy responses when compared with TRAD in trained individuals. This review was not previously registered.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11022786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46395838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Single Bout of High Heels Dancing Causes an Increase in Circulating Markers of Muscle Tissue Degradation and MMP-3 in Young Healthy Women.","authors":"Jamila Silva, Leandro Borges, Eleine Weimann, Beatriz Belmiro Dias, Flavio Gomes Faria, Beatriz Ferreira Salgado, Paulo de Freitas, Tania Cristina Pithon-Curi, Elaine Hatanaka","doi":"10.1155/2023/8852889","DOIUrl":"10.1155/2023/8852889","url":null,"abstract":"<p><p>Prolonged wearing of high heels can cause chronic injury and inflammation. Herein, we investigated the presence of muscle injury, inflammation, and neutrophil function in young women after a single bout of stiletto dance class. Sixteen volunteers (23.4 ± 3.8 years; 61.7 ± 8.1 kg; 23.4 ± 2.3 kg/m²; and 27.2 ± 3.8% body fat) participated in the study. The plasma biomarkers matrix metalloproteinase 3 (MMP-3), muscle damage (myoglobin (Mb), total creatine kinase (CK), and lactate dehydrogenase (LDH)), and inflammation (interleukin 8 (IL-8), tumour necrosis factor-alpha (TNF-<i>α</i>), interleukin (IL]-1<i>β</i>, and IL-6) were quantified before and immediately after a single stiletto class (60 min) of moderate intensity. After class, our data showed that the plasma concentration of MMP-3, Mb, and CK increased by 56% (<i>p</i> = 0.04; <i>d</i> = 0.8), 113% (<i>p</i> = 0.007; <i>d</i> = 1.1), and 21% (<i>p</i> < 0.001; <i>d</i> = 0.4), respectively. Reactive oxygen species produced by neutrophils and the plasma concentration of IL-8, TNF-<i>α</i>, IL-1<i>β</i>, and IL-6 were not affected under the study conditions. We concluded that a single bout of stiletto dance class caused muscle damage but did not alter the plasma concentration of proinflammatory cytokines. These findings are crucial in preventing the progress of chronic injuries that are often noted in dancers with synovitis and arthritis.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11022759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46842071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Psychometric Properties of the Danish VISA-P.","authors":"Anne-Sofie Agergaard, Jonathan D Comins, Volkert Siersma, Nikolaj M Malmgaard-Clausen, Christian Couppe, Mikkel H Hjortshoej, Jens L Olesen, S Peter Magnusson","doi":"10.1155/2023/5291949","DOIUrl":"10.1155/2023/5291949","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of the current study was to conduct a rigorous assessment of the psychometric properties of the Victorian Institute of Sports Assessment-patellar tendinopathy (VISA-P).</p><p><strong>Methods: </strong>Rasch analysis, confirmatory factor analysis (CFA), and multivariable linear regression were used to assess the psychometric properties of the VISA-P questionnaire in 184 Danish patients with patellar tendinopathy who had symptoms ranging from under 3 months to over 1 year. A group of 100 healthy Danish persons was included as a reference for known-group validation.</p><p><strong>Results: </strong>The analyses revealed that the 8-item VISA-P did not fit a unidimensional model, yielded at best a 3-factor model, and exhibited differential item functioning (DIF) across healthy subjects versus people with patellar tendinopathy.</p><p><strong>Conclusion: </strong>VISA-P in its present form does not satisfy a measurement model and is not a robust scale for measuring patellar tendinopathy. A new PROM for patellar tendinopathy should be developed and appropriately validated, and meanwhile, simple pain scoring (e.g., numeric rating scales) and functional tests are suggested as more appropriate outcome measures for studies of patellar tendinopathy.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11022774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49624039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of Injuries during Judo Tournaments.","authors":"Jeroen Mooren, Amber L von Gerhardt, Irene T J Hendriks, Johannes L Tol, Sander Koëter","doi":"10.1155/2023/2713614","DOIUrl":"10.1155/2023/2713614","url":null,"abstract":"<p><strong>Objective: </strong>To determine the injury incidence proportion, distribution of injuries by anatomical location; injury type; injury severity, time loss; mechanism and situations of injuries; and the relative risk of injuries by gender, age, and weight categories during judo tournaments. <i>Study Design</i>. It is a systematic review. <i>Data Sources</i>. A systematic review of the literature was conducted via searches in PubMed, EMBASE, Web of Science, CINAHL, SPORTDiscus, Google Scholar, and PEDro. <i>Eligibility Criteria</i>. All original studies on the incidence of injuries during judo tournaments were included.</p><p><strong>Results: </strong>Twenty-five studies were included out of the 1979 studies. Using the modified AXIS tool score for quality assessment, seven were rated as having good quality, nine were rated as having fair quality, and four were rated as having poor quality. The injury incidence proportion during tournaments ranged from 2.5% to 72.5% for injuries requiring medical evaluation and 1.1% to 4.1% for injuries causing time loss (i.e., inability to continue game participation). The most commonly reported injury location was the head, followed by the hand, knee, elbow, and shoulder. The most frequent types of injury were sprains, followed by contusions, skin lacerations, strains, and fractures. In judo tournaments, injuries were more often sustained during standing fights (tachi-waza) than in ground fights (ne-waza).</p><p><strong>Conclusion: </strong>The tournament injury incidence proportion ranged from 2.5% to 72.5% for injuries requiring medical attention and 1.1% to 4.1% for injuries causing time loss. The head was the most frequently injured body part, and sprain was the most frequent injury type. However, current reports on injuries during judo tournaments are heterogeneous and inconsistent, limiting our understanding of in-match injury risks. Future studies should utilize the guidelines of the International Olympic Committee consensus meeting statement on the methodological approach to injury reporting. We recommend a judo-specific extension of this statement to fit the unique features of judo sports practice.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11022761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44076367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of a 12-Month Exercise Intervention in Postsurgical Colorectal Cancer Patients.","authors":"Melanie Heitkamp, Bianca Spanier, Pia von Korn, Sebastian Knapp, Claudia Groß, Bernhard Haller, Martin Halle","doi":"10.1155/2023/4488334","DOIUrl":"10.1155/2023/4488334","url":null,"abstract":"<p><strong>Background: </strong>Extensive physical activity (PA; ≥18 MET<i>∗</i>h/week, MET metabolic equivalent of tasks hours) postcancer diagnosis has shown favorable effects on colorectal cancer disease-free survival. However, the feasibility of introducing this high volume of PA in this patient group is unclear. Therefore, the aim of the F-PROTECT study was to evaluate the feasibility of extensive and prolonged PA (≥18 MET<i>∗</i>h/week over 12 months) in colorectal cancer patients with the primary objectives to (1) recruit 50 patients within 12 months and (2) reach an attendance rate of ≥70%.</p><p><strong>Methods: </strong>Single-armed, bicentric, prospective intervention study in colorectal cancer patients (≤80 years; UICC II/III Union for International Cancer Control) after histopathological confirmed <i>R</i>0-resection who were consecutively recruited from visceral surgery units of 10 clinics in Germany. Recruitment rates were calculated using screening logs. Intervention was a 12-month endurance-focused exercise program with supervised and home-based training. Attendance rates defined as ≥70% participation in training sessions were calculated by training diaries.</p><p><strong>Results: </strong>Out of 521 patients who were screened for eligibility, 50 (23 female; 59 ± 10 years, UICC 44% II, 56% III; adjuvant chemotherapy 60%) were recruited within 15 months. Mean duration between surgery and first training was 103 ± 57 days. Training attendance rate was 64% (including 9 dropouts). Six (12%) participants reached ≥18 MET<i>∗</i>h/week in ≥70% of training sessions between 4-12 months. 28 adverse events (<i>n</i> = 9 serious) occurred, however, were not assessed as training related.</p><p><strong>Conclusions: </strong>The present intervention involving a combination of supervised and home-based exercise training in postsurgical colorectal cancer patients was not feasible. Strategies specifically designed for this patient group must be developed and investigated to motivate long-term PA. <i>Registration</i>. The study was prospectively registered at clinicaltrials.gov (NCT01991847).</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11022773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64794738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Injuries in Physical Education Teacher Students: Differences between Sex, Curriculum Year, Setting, and Sports.","authors":"Maarten Barendrecht, Carl C Barten, Willem van Mechelen, Evert Verhagen, Bouwien C M Smits-Engelsman","doi":"10.1155/2023/8643402","DOIUrl":"10.1155/2023/8643402","url":null,"abstract":"<p><strong>Background: </strong>Injury risk is high in Physical Education Teacher Education (PETE) students. Insights into specific injury locations per sex, setting, sports, and curriculum year are needed to develop preventive measures.</p><p><strong>Purpose: </strong>To compare injury distributions by body locations in PETE students and how these distributions differ by sex, type, onset, curriculum year, settings, or sports.</p><p><strong>Methods: </strong>In a historical cohort study over 14 years, data from 2899 students (male 76.2%, <i>n</i> = 1947) enlisted in the first three years of a PETE curriculum were analysed. Injuries reported at the institution's medical facility were categorised per sex, body location, onset, type, setting, sports, and curriculum year.</p><p><strong>Results: </strong>Forty-three percent (<i>n</i> = 1247) of all students (female 54.9%, <i>n</i> = 523, male 37.2%, and <i>n</i> = 429) reported a total of 2129 injuries (freshmen 56.4%; 2^nd year 28.2%; 3^rd year 15.5%). The most prevalent sudden onset injury locations (63.4% of all injuries) were the ankle (32.5%) and knee (16.6). The most prevalent gradual onset injuries were the lower leg (27.8%) and knee (25.2%). Joint/ligament injuries (45.8%) and muscle/tendon injuries (23.4%) were the most prevalent injury types. Proportions for injury locations and injury types differed significantly between curriculum years. Injury prevalence per setting and sport differed significantly between the sexes. Injury locations differed significantly between sports and between the sexes per sport.</p><p><strong>Conclusion: </strong>A differential approach per injury location, onset, type, sex, setting, sports, and curriculum year is needed to develop adequate preventive measures in PETE studies. The engagement of precurricular, intracurricular, and extracurricular stakeholders is needed in the development of these measures.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11023724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45266210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supervised, Heavy Resistance Training Is Tolerated and Potentially Beneficial in Women with Knee Pain and Knee Joint Hypermobility: A Case Series.","authors":"Peter Henriksen, Tina Junge, Jens Bojsen-Møller, Birgit Juul-Kristensen, Jonas Bloch Thorlund","doi":"10.1155/2022/8367134","DOIUrl":"10.1155/2022/8367134","url":null,"abstract":"<p><strong>Introduction: </strong>Adults with generalised joint hypermobility including knee joint hypermobility (GJHk) report more knee joint symptoms when compared to adults without GJHk. There is no consensus on best practice for symptom management. For instance, controversy exists regarding the appropriateness and safety of heavy resistance training as an intervention for this specific group. This case series aims to describe a supervised, progressive heavy resistance training program in adults with GJHk and knee pain, the tolerability of the intervention, and the outcomes of knee pain, knee-related quality of life, muscle strength, proprioception, and patellar tendon stiffness through a 12-week period.</p><p><strong>Materials and methods: </strong>Adults with GJHk and knee pain were recruited to perform supervised, progressive heavy resistance training twice a week for 12 weeks. The main outcome was the tolerability of the intervention. Secondary outcomes were knee pain during a self-nominated activity (VAS_NA); Knee injury and Osteoarthritis Outcome Score (KOOS); Tampa Scale of Kinesiophobia (TSK); maximal quadriceps voluntary isometric contraction and rate of torque development; 5 repetition maximum strength in five different leg exercises; single leg hop for distance; knee proprioception and patellar tendon stiffness.</p><p><strong>Results: </strong>In total, 16 women (24.2 years, SD 2.5) completed at least 21/24 training sessions. No major adverse events were observed. On average, VAS_NA decreased by 32.5 mm (95% CI 21.4-43.6), in addition to improvements in KOOS and TSK scores. These improvements were supported by an increase in all measures of lower extremity muscle strength, knee proprioception, and patellar tendon stiffness.</p><p><strong>Conclusion: </strong>Supervised heavy resistance training seems to be well tolerated and potentially beneficial in young women with GJHk and knee pain.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11022762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45733434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}