Translational sports medicine最新文献

{"title":"Beyond Return-To-Sport: Mapping ACL Injury History in Currently Active Female Football Players From Youth to Senior Elite Level.","authors":"Mette K Zebis, Mikkel B Clausen, Connie Linnebjerg, Mette Hansen, Jesper Bencke, Lars L Andersen, Per Hölmich, Kristian Thorborg","doi":"10.1155/tsm2/4174828","DOIUrl":"https://doi.org/10.1155/tsm2/4174828","url":null,"abstract":"<p><strong>Purpose: </strong>This study determines the prevalence of ACL injury history among currently active female football players across age groups and playing levels and examines the association between ACL injury history and activity-related knee pain.</p><p><strong>Methods: </strong>A total of 1026 active Danish female youth- and senior-league football players were invited to an online questionnaire (response rate: 751 [73%]) on (1) ACL injury history and (2) present knee pain during physical activity. Prevalence was calculated separately according to age (youth vs senior) and playing level (non-elite vs elite). Logistic regression analyses investigated factors associated with the prevalence of ACL injury history and activity-related knee pain, respectively.</p><p><strong>Results: </strong>The prevalence of ACL injury history was 5.0% (95% confidence interval [CI] 3.3%-7.4%) in youth football and 14.8% (95% CI 10.6%-19.8%) in senior football. The prevalence of activity-related knee pain was comparable between youth (24.6%, 95% CI 20.8%-28.7%) and senior football players (26.0%, 95% CI 20.7%-31.9%). Comparable prevalence of ACL injury history and knee pain was reported at elite and non-elite level. ACL injury history was strongly associated with activity-related knee pain (OR = 5.4-8.7, <i>p</i> < 0.0001).</p><p><strong>Conclusion: </strong>Playing with a previous ACL injury is common in active female football players, particularly at senior levels (nearly 1 in 6 elite players). The strong association between ACL injury history and activity-related knee pain underscores the long-term negative consequences. This study highlights the need for secondary and tertiary prevention strategies in female football.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"4174828"},"PeriodicalIF":1.9,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13122428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Velocity-Dependent Stress Changes in the Hamstring Muscle-Tendon Complex: A Study Using Human Cadavers.","authors":"Gakuto Nakao, Kazuma Yamagata, Risa Adachi, Koki Ishiyama, Kazuyoshi Kozawa, Kanna Nagaishi, Masaki Katayose, Keigo Taniguchi","doi":"10.1155/tsm2/4876843","DOIUrl":"https://doi.org/10.1155/tsm2/4876843","url":null,"abstract":"<p><p>Hamstring strain injuries frequently occur during high-speed running, when muscle tension is markedly increased. Given the viscoelastic properties of muscle, stress during elongation is expected to be velocity-dependent. Therefore, this study investigated the effect of elongation velocity on the stress in individual hamstring muscles. Seven Thiel-embalmed cadaveric lower limbs were used to isolate the biceps femoris long head, semimembranosus, and semitendinosus muscles. Specimens were fixed to a testing apparatus and passively elongated to 10% strain at five elongation velocities (20-300 mm/min), while tensile load and displacement were recorded. Muscle cross-sectional area was measured using ultrasound to calculate stress. A two-way repeated-measures analysis of variance examined the effects of muscle and velocity on stress at 10% strain. The results revealed no significant interaction between muscle and velocity (<i>p</i> > 0.05); however, both velocity and muscle had significant main effects on stress (<i>p</i> < 0.001). Post hoc analysis indicated that stress increased significantly with velocity (20 mm/min: 44.6 kPa, 50 mm/min: 47.4 kPa, 100 mm/min: 50.8 kPa, 200 mm/min: 56.4 kPa, 300 mm/min: 61.1 kPa). These findings suggest that stress in the hamstring muscles increases with elongation velocity, which may contribute to the risk of strain injuries during high-speed running. However, the results should be interpreted in the context of cadaveric testing and elongation velocities that are substantially lower than those observed in vivo.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"4876843"},"PeriodicalIF":1.9,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13096932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise-Induced Hypoalgesia Following Blood Flow Restriction in Rotator Cuff Repair Rehabilitation: A Randomized Crossover Clinical Trial.","authors":"Felipe Ponce-Fuentes, Iván Cuyul-Vásquez, Joaquín Salazar-Méndez, Enrique Lluch, Luis Suso-Martí, Chad Cook, Filip Struyf, José Granell Casaña, Joaquín Calatayud","doi":"10.1155/tsm2/4698970","DOIUrl":"10.1155/tsm2/4698970","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the acute effect on exercise-induced hypoalgesia (EIH) between isometric exercise with blood flow restriction (BFR) and isometric exercise alone in adults undergoing arthroscopic RC repair and to determine the level of correlation between EIH and kinesiophobia, disability and quality of life.</p><p><strong>Design: </strong>Blinded randomized crossover clinical trial.</p><p><strong>Patients: </strong>Twenty-three adults with degenerative rotator cuff (RC) repair.</p><p><strong>Intervention: </strong>Patients completed three shoulder isometric exercises. They were randomized to receive isometric exercises alone (control intervention) or isometric exercises with BFR (experimental intervention) in the first session and the alternate condition in the next session.</p><p><strong>Outcomes: </strong>Primary outcomes included pressure pain threshold (PPT) and conditioned pain modulation (CPM), assessed before, immediately after, and 10 min after isometric exercises with BFR and isometric exercises alone.</p><p><strong>Results: </strong>In the affected limb, BFR isometric exercises increased PPT immediately after exercise in upper trapezius (MD: 0.4 kg/cm² [CI_95% 0.1 to 0.9]), and in the unaffected limb, BFR isometric exercises increased deltoid PPT immediately after exercise (MD: 0.4 kg/cm² [CI_95% 0.1 to 0.7]). However, post hoc between-group comparisons showed that no significant differences existed between BFR and control at any time point, as all CI_95% crossed zero and these changes did not exceed the minimum detectable change (≈1.1 kg/cm²). Besides, isometric exercise alone increased deltoid CPM immediately after in affected limb (MD: 30.1% [CI_95% 10.8 to 49.4]) and 10 min after exercise in unaffected limb (MD: 12.0% [CI_95% -0.4 to 24.4]). No significant changes were found in clinical pain intensity measured by the visual analog scale (VAS) at any time point. Statistically significant weak correlations were found between PPT with Western Ontario Rotator Cuff (WORC) index (<i>r</i> = -0.322 for sport, <i>r</i> = -0.331 for work, <i>r</i> = -0.302 for lifestyle; <i>p</i> < 0.05) and Shoulder Pain Disability Index (SPADI) (<i>r</i> = -0.309; <i>p</i> < 0.05), respectively.</p><p><strong>Conclusion: </strong>A single session of low-intensity isometric exercises with BFR did not produce a clinically meaningful EIH response nor was it superior to isometric exercise alone in patients after RC repair. The observed statistical signals did not reach the minimum detectable change, and the inconsistent CPM shifts suggest that BFR does not provide an additional acute advantage for endogenous pain modulation in this early postoperative stage. <b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT06924112.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"4698970"},"PeriodicalIF":1.9,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13087449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Neuromuscular Conditioning in Football Players Through Single-Leg and Double-Leg Cycling: A Randomized Controlled Trial.","authors":"Jitin Chahal, Moattar Raza Rizvi, Ankita Sharma, Shishir Nigam, Waqas Sami","doi":"10.1155/tsm2/5535929","DOIUrl":"https://doi.org/10.1155/tsm2/5535929","url":null,"abstract":"<p><strong>Background: </strong>Football requires high levels of neuromuscular conditioning to meet the demands of explosive actions such as sprinting, cutting, and kicking, while minimizing the risk of lower limb injuries-especially hamstring strains linked to muscle imbalances. Single-leg cycling (SLC), a form of unilateral training, may offer superior neuromuscular adaptations compared to traditional double-leg cycling (DLC). This study aimed to compare the effects of SLC and DLC on lower limb strength, anaerobic power, fatigue resistance, agility, and sprint performance in competitive football players.</p><p><strong>Methods: </strong>A four-week, assessor-blinded randomized controlled trial was conducted on 42 male football players (aged 18-26), allocated equally to SLC (<i>n</i> = 21) and DLC (<i>n</i> = 21) groups. Both groups underwent biweekly cycling sessions. Pre- and postintervention assessments included isokinetic peak torque of knee flexors and extensors, hamstring-to-quadriceps (H/Q) ratio, peak and minimum power, fatigue index (RAST), 20-m zig-zag agility test, and 30-m Sprint Test.</p><p><strong>Results: </strong>Both groups showed significant improvements in anaerobic performance metrics (peak and minimum power, <i>p</i> < 0.001). However, SLC yielded significantly higher gains in knee flexor peak torque (Δ + 46.7%, <i>p</i> < 0.001) and H/Q ratio (Δ + 30.2%, <i>p</i> = 0.02), indicating superior hamstring activation and improved muscle balance. Fatigue index significantly decreased only in the SLC group (Δ - 7.3%, <i>p</i> = 0.04), reflecting enhanced anaerobic endurance. SLC also resulted in greater improvements in agility (Δ - 5.9%) and sprint performance (Δ - 8.1%) compared to DLC (<i>p</i> < 0.001), suggesting improved neuromuscular coordination and explosive capability. Knee extensor torque increased modestly in both groups, with no significant between-group difference (<i>p</i> = 0.46).</p><p><strong>Conclusion: </strong>SLC training offers superior benefits over DLC in improving lower limb strength balance, fatigue resistance, agility, and sprinting in football players. It may serve as a targeted conditioning strategy to enhance performance and reduce injury risk in sport-specific contexts. <b>Trial Registration:</b> Clinical Trials Registry-India (CTRI): CTRI/2023/06/053941.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"5535929"},"PeriodicalIF":1.9,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Anxiety and Depression Using Preconcussion Screening Assessments in Collegiate Athletes.","authors":"Chase R Siewert, Caroline J Ketcham, Eric E Hall","doi":"10.1155/tsm2/6927094","DOIUrl":"10.1155/tsm2/6927094","url":null,"abstract":"<p><p>Accurate identification of anxiety and depression in collegiate athletes is critical to timely intervention. Baseline concussion testing, such as the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT), may provide a unique, practical avenue for screening mental health concerns. The objective of this study was to determine whether the symptom cluster scores from ImPACT can predict anxiety and depression in collegiate athletes. 560 athletes (43.7% female; 16% ADHD) completed baseline assessments preseason. Symptom clusters (e.g., affective) were derived from ImPACT and compared with scores on the Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9). Hierarchical regression analyses examined whether ImPACT clusters and demographic factors could predict anxiety and depression. Gender and ADHD explained a small but significant portion of the variance in depression (<i>R</i> ² change = 0.040, <i>p</i> < 0.001), cognitive clusters (<i>R</i> ² change = 0.018, <i>p</i> < 0.001), and affective clusters (<i>R</i> ² change = 0.259, <i>p</i> < 0.001). In the prediction of anxiety, the affective cluster was again the strongest predictor, contributing to a substantial increase in explained variance (<i>R</i> ² change = 0.257, <i>p</i> < 0.001), followed by demographic factors, sex, and ADHD, which explained a smaller portion of the variance (<i>R</i> ² change = 0.035, <i>p</i> < 0.001). ImPACT concussion symptom clusters appear to be a useful tool for preemptive screening of anxiety and depression in collegiate athletes. Including this utility in existing concussion protocols, which ubiquitously use ImPACT, may facilitate earlier identification of at-risk individuals for a more targeted intervention to support student-athletes' psychological well-being.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"6927094"},"PeriodicalIF":1.9,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12905455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146204114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Kidney Injury Associated With Dehydration Protocol Used by Combat Sports Athletes.","authors":"Antônio André Jarsen Pereira, Lucas Magri, Marina de Moura Bello, Andréia Cristina Febba Gomes, Carlos Eduardo Neves Amorim, Lilian Caroline Gonçalves de Oliveira, Nestor Schor, Dulce Elena Casarini","doi":"10.1155/tsm2/2946676","DOIUrl":"10.1155/tsm2/2946676","url":null,"abstract":"<p><p>The increase in combat sports practice and the creation of weight divisions for fairer competitions led to dehydration practice as a strategy of inclusion in inferior divisions. However, this technique can damage kidney and heart functions due to alterations in blood volume. This study evaluated the acute effects of weight loss through dehydration on the kidney function of Mixed Martial Arts and Muay Thai fighters. The sample was composed of 30 athletes of both Mixed Martial Arts (<i>n</i> = 15) and Muay Thai (<i>n</i> = 15) fighters. Both groups went through two protocols for collecting data about the athlete's profile, vital signs, and urinary and blood samples in three different moments: before weigh-in, official weigh-in day, and fight day. The athletes' profiles and the dehydration methods employed were found to be consistent with those reported in the literature. The participants lost weight 1 month before the fight and had alterations that developed into glycosuria, leukocyturia, and proteinuria noted on both official weigh-in and combat days. Proteinuria and high creatinine depuration suggest acute kidney damage with an increase in filtration rate due to dehydration. As shown, there is a necessity for proper athlete orientation regarding dehydration and possible damage to the body's physiological integrity and sport performance, and developing a guide on more appropriate weight control protocols that do not put athletes' health at risk should be established and publicized.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"2946676"},"PeriodicalIF":1.9,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12863454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Which Protein-Based Dietary Supplements Most Effectively Enhance Fat-Free Mass and Strength Gains in Healthy Adults Undergoing Resistance Training? A Network Meta-Analysis.","authors":"Marcos D M Drummond, Ronaldo A D Silva, Nelson Carvas Junior, Miércio S Melo, Matheus H L Ferreira","doi":"10.1155/tsm2/5557511","DOIUrl":"10.1155/tsm2/5557511","url":null,"abstract":"<p><strong>Background: </strong>Various protein-based dietary supplements are widely used by individuals engaged in strength training to optimize gains in muscle strength and fat-free mass. However, gaps remain in the scientific literature regarding a comprehensive comparison-particularly the effectiveness of different types of supplemented proteins in healthy adults. This systematic review and network meta-analysis aimed to compare the effectiveness of protein-based dietary supplements, combined with strength training, on increasing muscle strength and fat-free mass in healthy adults.</p><p><strong>Methods: </strong>A network meta-analysis was conducted using randomized controlled trials evaluating different protein supplements combined with strength training. The outcomes assessed were muscle strength (primary) and fat-free mass (secondary). The search was performed in PubMed, Scopus, and Embase up to May 2024, with no restrictions on language or publication date.</p><p><strong>Results: </strong>A total of 78 studies were included, comprising 4755 participants across two outcomes and involving 13 types of protein supplements, plus placebo and control groups. Compared to placebo, for strength, collagen was the most effective supplement (SMD = 0.41; 95% CI: 0.09 to 0.73; <i>p</i> = 0.0125; SUCRA 88.05%), followed by whey protein (SMD = 0.15; 95% CI: 0.03 to 0.27; <i>p</i> = 0.0145; SUCRA 64.34%). The other supplements showed no statistically significant differences compared to placebo (<i>p</i> > 0.05). For fat-free mass, results were similar. Collagen showed a statistically superior effect (SMD = 0.94; 95% CI: 0.48 to 1.40; <i>p</i> < 0.0001; SUCRA 98.92%), followed by whey protein (SMD = 0.16; 95% CI: 0.05 to 0.28; <i>p</i> = 0.0051; SUCRA 60.23%). Other supplements showed no statistically significant differences (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Collagen and whey protein are the only protein supplements effective in enhancing strength training effects. Moreover, collagen shows a superior effect compared to whey protein for both outcomes.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"5557511"},"PeriodicalIF":1.9,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12862422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Dual-Task Paradigm for Return-to-Sport Screening After ACL Injury: A Pilot Study.","authors":"Alva Lövgren, Andrew Strong, Carl-Johan Boraxbekk, Jonas L Markström","doi":"10.1155/tsm2/1073180","DOIUrl":"10.1155/tsm2/1073180","url":null,"abstract":"<p><strong>Background: </strong>Current return-to-sport screening paradigms after anterior cruciate ligament (ACL) injury are inadequate as they fail to reflect cognitive-motor sports demands. This pilot study aimed to evaluate dual-task ability in individuals with ACL reconstruction (ACLR) using a novel dual-task test paradigm. Specifically, we compared (1) cognitive and motor performance between individuals with ACLR and controls, (2) hop test performance between the injured and non-injured legs within the ACLR group, and (3) performance across test-retest sessions.</p><p><strong>Materials and methods: </strong>Twenty sports active individuals (10 ACLR, 10 controls) performed the dual-task paradigm twice within a week, comprising a cognitive test, a dual-task drop-vertical hop test, and an upper-body hand-tapping test. All tests incorporated a visuospatial working-memory task (cognitive performance), with the latter two additionally engaging attention, decision-making, and inhibitory control (motor performance). Between-group, between-leg, and test-retest differences were analyzed using independent and paired <i>t</i>-tests with Cohen's d effect sizes (ESs). Test-retest reliability was examined using intraclass correlation coefficient (ICC), along with the within-person standard deviation and minimal detectable change.</p><p><strong>Results: </strong>No significant differences were observed between ACLR and controls at the first test session (<i>p</i> = 0.09 - 0.34; ESs = 0.19-0.62 [very small-medium]), although ACLR mean performances were 3.8%-14.1% lower. At retest, ACLR performed significantly worse than CTRL for most outcomes (<i>p</i> = 0.01 - 0.03; ESs = 0.91-1.17 [large]) and showed smaller improvements for a hop test outcome (<i>p</i> = 0.04; ES = 0.97 [large]). No differences were found between ACLR legs, both groups improved across test sessions, and test-retest reliability was excellent for ACLR (ICCs = 0.74-0.97) and ranged from poor to excellent in CTRL (ICCs = 0.19-0.86).</p><p><strong>Conclusions: </strong>This pilot study demonstrates the feasibility and preliminary reliability of the dual-task paradigm, particularly within the ACLR group. Poorer cognitive, hop, and upper-body test performances and smaller test-retest improvements for the ACLR group suggest persistent dual-task deficits following injury, supporting the paradigm's utility for ecologically valid ACL rehabilitation and return-to-sport assessment.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"1073180"},"PeriodicalIF":1.9,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12788982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145954192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lisfranc Injuries: Latest Updates on Diagnostics and Management.","authors":"Ahmad Hammad, Yasser Ahmad, John Abdelnour","doi":"10.1155/tsm2/3933956","DOIUrl":"10.1155/tsm2/3933956","url":null,"abstract":"<p><p>The Lisfranc ligamentous complex is the principal stabilizer of the tarsometatarsal joint and functions as the midfoot keystone. Injuries often follow an axial or rotational load applied to a plantarflexed foot, producing ligamentous disruption or, in severe cases, fracture-dislocation of the tarsometatarsal complex. Up to one-third of Lisfranc injuries are initially missed, particularly in low-energy mechanisms or polytrauma settings. Weight-bearing radiographs are essential for detecting subtle injuries and uncovering diastasis between the medial cuneiform and the second metatarsal. The Myerson classification categorizes injuries based on joint congruity, the direction of displacement, and extent of involvement. The decision to pursue conservative or surgical treatment depends on the Lisfranc ligament stability and displacement. Nonoperative management is appropriate only in nondisplaced injuries; delayed treatment can result in persistent midfoot pain, arch collapse, post-traumatic arthritis, and diminished function. Surgical techniques include open reduction and internal fixation, primary arthrodesis, bridge plating, suture button fixation, and percutaneous approaches. Lateral column injuries involving the fourth and fifth tarsometatarsal joints are advised to be treated with K-wire fixation. Anatomic alignment is the strongest predictor of successful recovery and return to activity. Residual displacement > 2 mm is associated with inferior outcomes and significantly reduced return-to-play rates, particularly in athletes who can have lasting effects even with successful fixation and may not reach preinjury performance levels. Optimal management is yet to be determined, and inadequate fixation increases poor outcomes, underscoring the importance of early recognition, precise reduction, and appropriate fixation strategy. This study is novel and integrates recent evidence including diagnostic and prognostic utility of weight-bearing, the clinical outcomes and biomechanics of treatment approaches including flexible fixation constructs such as suture button systems, and postoperative outcomes including gait analysis, return-to-play, and athletic performance outcomes.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"3933956"},"PeriodicalIF":1.9,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12782322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145954121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Handgrip Strength and Markers of Insulin Resistance and Inflammation in Childhood and Adolescence: A Systematic Review With Meta-Analysis.","authors":"Takashi Abe, Ricardo B Viana, Akemi Abe, Shuichi Machida, Hisashi Naito, Jeremy P Loenneke","doi":"10.1155/tsm2/1091342","DOIUrl":"10.1155/tsm2/1091342","url":null,"abstract":"<p><strong>Background: </strong>Research on the association between changes in handgrip strength (HGS) and risk factors for lifestyle-related diseases in children and adolescents may help clarify the inverse association between HGS and morbidity/mortality.</p><p><strong>Objective: </strong>This systematic review with meta-analysis aimed to investigate the cross-sectional and longitudinal associations between HGS and markers of insulin resistance and inflammation in children and adolescents.</p><p><strong>Methods: </strong>Observational studies that investigated the cross-sectional and/or longitudinal associations between HGS and markers of insulin resistance and inflammation in children and adolescents were searched. Summary effect size measures were calculated using a random-effects model estimation and reported as Fisher's <i>r</i>-to-<i>z</i> transformed correlation coefficients and 95% confidence intervals.</p><p><strong>Results: </strong>Fifteen studies (12 cross-sectional, two cross-sectional and longitudinal, and one longitudinal) were included in the systematic review, of which 11 studies were also included in the meta-analyses for cross-sectional correlation. Relative (per body mass) but not absolute HGS was significantly associated (very low evidence) with markers of insulin resistance. Relative HGS was also significantly associated (very low evidence) with most of the inflammatory markers investigated. The three longitudinal studies included had insufficient information to perform a meta-analysis.</p><p><strong>Conclusions: </strong>The results from cross-sectional studies indicated the association (very low evidence) between HGS and several markers of insulin resistance and inflammation existed when studies utilized the relative HGS per body mass. However, no significant relationship was found when studies used absolute HGS. Furthermore, as longitudinal studies were limited, future longitudinal follow-up studies are an important means of resolving these issues.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2026 ","pages":"1091342"},"PeriodicalIF":1.9,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12782331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145954130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}