Translational perioperative and pain medicine最新文献

{"title":"Therapeutic Potential of Salvinorin A and Its Analogues in Various Neurological Disorders.","authors":"Joseph Cichon, Renyu Liu, Hoang V Le","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"9 2","pages":"452-457"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40608214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative Intercostal Nerve Cryoneurolysis for Post-Thoracotomy Pain Control: A Case Discussion.","authors":"Xiaowei Lu, Ning Miao, Sandra Orfgen, Andrew Mannes","doi":"10.31480/2330-4871/159","DOIUrl":"10.31480/2330-4871/159","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"9 3","pages":"458-463"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9522113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Brief Overview of the Neuropharmacology of Opioid Addiction.","authors":"John R Grothusen,&nbsp;Julie A Blendy,&nbsp;Gordon A Barr","doi":"10.31480/2330-4871/165","DOIUrl":"https://doi.org/10.31480/2330-4871/165","url":null,"abstract":"<p><p>The world is in the midst of an opioid crisis. Nearly 92,000 persons in the U.S. alone died from illicit drugs and prescription opioids in 2020 [1]. This number does not include the countless other individuals who die as a result of the violent crime that accompanies the illicit drug trade. To address this crisis, we need to appreciate aspects of drug addiction. The goal of this brief review is to highlight some major facets of addiction neurobiology, focused on opioids, to provide a basic understanding of the research and terminology encountered in more detailed in-depth articles and discussions on addiction.</p>","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"9 4","pages":"491-496"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019698/pdf/nihms-1872821.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10157822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurocysticercosis: A Rare Cause of Headache Needing Craniotomy.","authors":"Xiaowei Lu, Ning Miao, Andrew Mannes","doi":"10.31480/2330-4871/154","DOIUrl":"10.31480/2330-4871/154","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":"434-437"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40554702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why We Shouldn't Ask PACU Patients: 'Are You Having Pain?'","authors":"Barry L Friedberg, Andrew Mannes","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"9 4","pages":"497-498"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9342351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Effects of Critical Care Insults on Lipoprotein Metabolism","authors":"Laudanski Krzysztof, Hajj Jihane, Riedel Ciara, Liu Da, Maret Josh, Restrepo Mariana, Siddiq Kumal","doi":"10.31480/2330-4871/146","DOIUrl":"https://doi.org/10.31480/2330-4871/146","url":null,"abstract":"Background: Several reports demonstrated acute changes in lipoprotein profiles during the acute phase of critical care illness (CCI), with significantly fewer investigations suggesting the persistence of lipid abnormalities past 28 days from onset of CCI, or into recovery. Theoretically, their persistence into a recovery of CCI may profoundly impact health as dyslipidemias are considered critically important in the natural history of atherosclerosis. Considering the increased incidence of survivorship after CCI (sepsis, trauma, severe surgery, burn), and the profound effect of even small changes in lipid makeup over time, investigating the persistence of lipid profile abnormalities addresses important health concerns. Here, we conducted a comprehensive review focusing on long-term (28 days or greater) lipoprotein abnormalities after CCI onset. Methods: The supervised, narrative literature review utilized the PubMed, EBSCO, and Google Scholar databases using keywords (sepsis, trauma, surgery, stroke, recovery). In addition, we pursued studies focusing on 28 days observation periods, at minimum, after the resolution of acute inflammation. We identified 26 studies fitting our criteria, with another 11 included because of their input value. Results: Only a handful of studies investigated long-term lipid profiles after sepsis, trauma, surgery, or traumatic brain injury. Persistent depression of HDL-c and LDL-c serum levels were the hallmarks of several post-CCI conditions. Furthermore, few investigators reported an increase in the oxidation of LDL. One animal study linked these observations to acceleration in the atherosclerotic process in animals surviving weeks after sepsis resolution. Conclusions: Scant data indicates that recovery from critical care illness is associated with several persistent lipoprotein abnormalities. Numerous gaps in knowledge persist, particularly in terms of the clinical translation of observed lipid abnormalities into long-term cardiovascular outcomes post-CCI.","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49320717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Intrathecal rapamycin attenuates morphine-induced analgesic tolerance and hyperalgesia in rats with neuropathic pain\"","authors":"Xu Ji-Tian, Sun Linlin, Lutz Brianna Marie, Bekker Alex, Tao Yuan-Xiang","doi":"10.31480/2330-4871/148","DOIUrl":"https://doi.org/10.31480/2330-4871/148","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46189535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthetic Management in a Parturient with Advanced Amyotrophic Lateral Sclerosis Undergoing Dilation and Curettage","authors":"Morey Benjamin P, L. Hong, Chandler Cristina","doi":"10.31480/2330-4871/145","DOIUrl":"https://doi.org/10.31480/2330-4871/145","url":null,"abstract":"patients with ALS presenting for urgent or emergency procedures in addition to elective operations such as tracheostomy or gastrostomy tube placement represents a challenging task for the anesthesiologist. General anesthesia is problematic given the possibility of pulmonary aspiration, exaggerated responses to non-depolarizing neuromuscular blocking drugs (NMBDs), risk of hyperkalemic cardiac arrest with succinylcholine, and concern for postoperative respiratory depression Moreover, there has been concern for decades that neuraxial anesthesia could potentially exacerbate neuromuscular disorders, which led to hesitation when considering or epidural in Here, we describe the anesthetic management of a patient with advanced ALS undergoing a dilation and curettage (D&C) for pregnancy termination, and further discuss the anesthetic implications and physiologic challenges for the parturient with ALS. was Abstract Background: Amyotrophic lateral sclerosis (ALS) is a rare but debilitating neuromuscular disorder that is characterized by degeneration of both upper and lower motor neurons and successive muscle denervation. More than 50% of patients pass away within 3 years of symptom onset from fatal respiratory muscle failure. Respiratory decompensation in a pregnant patient with ALS is of particular concern given the substantial physiologic increase in minute ventilation that starts early in pregnancy. Case presentation: 38-year-old female with medical history of advanced ALS, asthma, prior substance abuse, and recurrent urinary tract infections presented with right-sided abdominal and flank pain and 13 weeks of incident pregnancy. The patient was quadriparetic at baseline, had significant bulbar symptoms, and required BiPAP at home. After discussion with a multidisciplinary team of experts, the patient decided to terminate the pregnancy given the substantial risk of exacerbating her already debilitating ALS symptoms. The patient received a combination of paracervical local block and monitored anesthesia care (MAC). The procedure was without incident, and the patient was discharged home the next day after an uneventful postoperative course. Conclusion: It is strongly recommended maintaining a steadfast commitment to patient safety and avoiding general anesthesia in ALS patients unless there are irrefutable contraindications to MAC, regional block or neuraxial anesthesia.","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45291612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ciprofol: A Novel Medication from Development towards Clinical Use","authors":"Tingting Wang, S. Yao, Limin Zhang, Y. Liu","doi":"10.31480/2330-4871/147","DOIUrl":"https://doi.org/10.31480/2330-4871/147","url":null,"abstract":"most common adverse reactions elicited by propofol [5]. Therefore, in order to find new medications that can overcome these limitations and have the anesthetic effect similar to propofol, Haisco Pharmaceutical Group Co., Ltd. independently developed the new anesthetic medication HSK3486 (ciprofol) [6,7], which is expected to become a widely used anesthesia/sedation medication in clinical practice. This review summarizes the current relevant research literature and clinical trial information available globally, so as to facilitate the readers to understand its mechanism of action and clinical characteristics, and thereby provide the theoretical basis for its further use in clinical practice.","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46706662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translational Role of Rodent Models to Study Ventilator-Induced Lung Injury","authors":"Y. Koichi, Koutsogiannaki Sophia","doi":"10.31480/2330-4871/149","DOIUrl":"https://doi.org/10.31480/2330-4871/149","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48557966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}