Translational perioperative and pain medicine最新文献

{"title":"Critical Hyperkalemia During Neurosurgery","authors":"Gundling Ke","doi":"10.31480/2330-4871/086","DOIUrl":"https://doi.org/10.31480/2330-4871/086","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44699342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Head Elevation by Ten Degrees in Prone Position Surgery Consistently Decreases and Minimizes Variation in Intraocular Pressure (IOP)","authors":"B. Matthew, W. Brian, R. Pavithra, C VallejoManuel, H. Ralph, W. Hong, E. Sanford","doi":"10.31480/2330-4871/085","DOIUrl":"https://doi.org/10.31480/2330-4871/085","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47189730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Stroke Prehospital Delay Summary Statement: A Global Battlefield","authors":"Zhao Jing, Ren Lijie, Abraham Siju, Li Dou, Kung David, Chao A-Ching, Fisher Marc, Liu Renyu","doi":"10.31480/2330-4871/083","DOIUrl":"https://doi.org/10.31480/2330-4871/083","url":null,"abstract":"An international symposium specifically focusing on prehospital delay and potential strategies to reduce prehospital delay for stroke was held in the Penn Wharton China Center on June 28th, 2018 in Beijing. More than 70 experts from across China and other countries and regions attended this symposium, which was streamed live across China. There were 11,318 active participants online during the symposium, indicating enormous enthusiasm for this topic. Prehospital delay for stroke patients is a critical global issue. It should be considered as a crisis in many developing countries and regions, requiring immediate implementation of practical strategies to reduce prehospital delay. The symposium focusing on prehospital delay for stroke patients generated very productive discussions on the causes of long prehospital delays, including poor public awareness and poor willingness to utilize emergency medical systems. Potential solutions and strategies discussed include the use of novel educational tools (Stroke 120 and Stroke 112, both of which are based on FAST: Face, Arm, Speech, Time) to improve awareness and emergency medical system utilization, establishment of robust emergency stroke care systems and stroke care maps, and an enhancement in governmental support etc. Removal of informed consent for thrombolytic therapy in some countries and regions was strongly recommended. As most of the proposed solutions are from expert opinions, future efforts could focus on testing these strategies and proposing new recommendations or guidelines for this specific important global health issue.","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43893712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient with Hyperkalemia for Surgery: Proceed or Postpone?","authors":"Huang Liang, Y. Weonpo, L. Henry","doi":"10.31480/2330-4871/082","DOIUrl":"https://doi.org/10.31480/2330-4871/082","url":null,"abstract":"Hyperkalemia is a medical condition that anesthesia providers frequently have to deal with. Anesthetics (succinylcholine) and anesthesia practice (hypoventilation) may worsen hyperkalemia. The decision to proceed with a scheduled surgical procedure in a patient with hyperkalemia can be very challenging; it is usually decided by a mutual agreement between surgery team and anesthesia providers. Intraoperative management strategies can include intravenous administration of calcium, sodium bicarbonate, insulin with/without glucose, or other alkalizing agent; inhalation of albuterol; hyperventilation can often be adopted to induce mild respiratory alkalosis to lower metabolic acidosis-induced hyperkalemia.","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43942450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Wish List to any Case Report","authors":"Meng Lingzhong","doi":"10.31480/2330-4871/080","DOIUrl":"https://doi.org/10.31480/2330-4871/080","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47503560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Synopsis of Contemporary Anesthesia Airway Management","authors":"C. Bohringer, J. Duca, Hong Liu","doi":"10.31480/2330-4871/081","DOIUrl":"https://doi.org/10.31480/2330-4871/081","url":null,"abstract":"New airway equipment has recently become available that has reduced morbidity and mortality. However, airway disasters still occur. This article discusses the prudent escalation of the use of advanced airway equipment to prevent these disasters. We illustrate when and how to use a gum elastic bougie and a video-laryngoscope (VL). We also strongly recommend the combined use of the VL together with a flexible intubation scope (FIS) for both asleep and awake intubation when dealing with a genuinely difficult airway. Blind intubations should no longer be performed today. When an airway has been recognized as difficult it is the safest to aim for an awake or at least a spontaneously breathing intubation if circumstances do not allow for an awake intubation. Emergency cricothyroidotomy needs to be prepared for so that it can be executed rapidly in case the attempted awake intubation leads to complete airway obstruction.","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"6 1","pages":"5 - 16"},"PeriodicalIF":0.0,"publicationDate":"2019-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47362914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The U.S. Department of Health and Human Services Pain Management Inter-Agency Task Force Emphasizes Patient-Centered Care in its Draft Report","authors":"Chen Jianguo","doi":"10.31480/2330-4871/079","DOIUrl":"https://doi.org/10.31480/2330-4871/079","url":null,"abstract":"","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46667543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Water Soluble G-protein Coupled Receptor Enabled Biosensors.","authors":"Renyu Liu,&nbsp;A T Charlie Johnson,&nbsp;Jeffery G Saven","doi":"10.31480/2330-4871/095","DOIUrl":"https://doi.org/10.31480/2330-4871/095","url":null,"abstract":"<p><p>This article will briefly overview our efforts in the engineering of water soluble variants of a G-protein coupled receptor (GPCR) and its novel applications to develop biosensors using such water soluble variants of GPCR. While the technologies using water soluble GPCR are still under development, they offer new tools and strategies to study the function of GPCR, explore potential new compounds for potential clinical usage, and monitor endogenous peptides in various physiological and pathological conditions.</p>","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"6 4","pages":"98-103"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37450105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Outcomes of Pediatric Hematopoietic Stem Cell Transplantation Recipients Requiring Intensive Care Unit Admission- A Single Center Experience.","authors":"Royce Kwon,&nbsp;Sophia Koutsogiannaki,&nbsp;Steven J Staffa,&nbsp;Koichi Yuki","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Although the outcome of pediatric hematopoietic stem cell transplantation (HSCT) has significantly improved, it remains to be associated with high mortality. Identifying patients at high risk of mortality may potentially help to triage clinical management. The primary objective of this study is to evaluate risk factors associated with mortality of patients who received HSCT and admitted to ICU using pediatric sequential organ failure assessment (pSOFA), one of pediatric severity scoring systems in intensive care unit (ICU).</p><p><strong>Methods: </strong>We performed retrospective review of electronic medical records of pediatric patients who received HSCT and were admitted to ICU in our institution between January 2010 and June 2018. Incidence of mortality was obtained, and risk factors associated with the mortality were examined using univariate and multivariable analyses.</p><p><strong>Results: </strong>The mortality rate of pediatric HSCT patients who were admitted to ICU as a whole was 27.9%. Patients were divided into three groups based on the number of HSCT required and timing of ICU admission. Patients who received first HSCT and admitted to ICU during the same hospital stay were the majority of the study population (Group A). d(pSOFA), which was defined as the difference between maximum pSOFA and admission pSOFA, greater than and equal to 7 best predicted mortality of Group A (the area under the ROC curve 0.850; 95% CI: 0.733-0.966). Univariate and multivariable analyses showed that an increase in neurologic and cardiovascular sub scores were independently associated with higher mortality (odds ratio (OR) 2.27; 95% CI: 1.32-3.93, and OR 2.69; 95% CI: 1.21-5.99, respectively).</p><p><strong>Discussion: </strong>In our single center study, pediatric HSCT patients who were admitted to ICU demonstrated a high mortality. Risk factor analysis demonstrated that patients with the progression of neurologic and cardiovascular injuries probed by pSOFA scoring system during their ICU stay were strongly associated with mortality.</p>","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"6 3","pages":"75-80"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37416610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Volatile Anesthetics as Sedatives for Acute Respiratory Distress Syndrome.","authors":"Sophia Koutsogiannaki,&nbsp;Motomu Shimaoka,&nbsp;Koichi Yuki","doi":"10.31480/2330-4871/084","DOIUrl":"https://doi.org/10.31480/2330-4871/084","url":null,"abstract":"<p><p>Acute respiratory distress syndrome (ARDS) remains to pose a high morbidity and mortality without any targeted therapies. Sedation, usually given intravenously, is an important part of clinical practice in intensive care unit (ICU), and the effect of sedatives on patients' outcomes has been studied intensively. Although volatile anesthetics are not routine sedatives in ICU, preclinical and clinical studies suggested their potential benefit in pulmonary pathophysiology. This review will summarize the current knowledge of ARDS and the role of volatile anesthetic sedation in this setting from both clinical and mechanistic standpoints. In addition, we will review the infrastructure to use volatile anesthetics.</p>","PeriodicalId":75245,"journal":{"name":"Translational perioperative and pain medicine","volume":"6 2","pages":"27-38"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.31480/2330-4871/084","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37262984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}