Translational biophotonics最新文献_第5页

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Translational biophotonics Pub Date : 2020-08-01 DOI: 10.1002/tbio.201990003

引用次数: 0

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Translational biophotonics Pub Date : 2020-08-01 DOI: 10.1002/tbio.201970006

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Diffuse reflectance spectroscopy as a potential method for nonmelanoma skin cancer margin assessment 漫反射光谱作为一种潜在的非黑色素瘤皮肤癌症边缘评估方法

Translational biophotonics Pub Date : 2020-06-10 DOI: 10.1002/tbio.202000001

Yao Zhang, Austin J. Moy, Xu Feng, Hieu T M Nguyen, Katherine R. Sebastian, J. Reichenberg, M. Markey, J. Tunnell

引用次数: 4

Light emitting fabrics for photodynamic therapy: Technology, experimental and clinical applications 光动力治疗用发光织物:技术、实验和临床应用

Translational biophotonics Pub Date : 2020-06-08 DOI: 10.1002/tbio.202000005

S. Mordon, E. Thecua, L. Ziane, F. Lecomte, P. Deleporte, G. Baert, A. Vignion-Dewalle

{"title":"Light emitting fabrics for photodynamic therapy: Technology, experimental and clinical applications","authors":"S. Mordon, E. Thecua, L. Ziane, F. Lecomte, P. Deleporte, G. Baert, A. Vignion-Dewalle","doi":"10.1002/tbio.202000005","DOIUrl":"https://doi.org/10.1002/tbio.202000005","url":null,"abstract":"A homogeneous and reproducible fluence rate delivery during clinical PDT (PhotoDynamic Therapy) plays a determinant role in preventing under-or overtreatment. The development of a flexible light source able to generate uniform light on all its surface would considerably improve the homogeneity of light delivery. The integration of plastic optical fibers into textile structures offers an interesting alternative. This article aims to describe briefly the technology used to develop Light Emitting Fabrics (LEF) and their use in vitro (CELL-LEF), in vivo (VIVO-LEF) for experimental evaluation of PDT. At last, the use of LEF for clinical applications is given by 3 examples. For in-vitro applications, the CELL-LEF device allows the illumination of several 96-well cell culture plates. For the VIVO-LEF, the system developed for PDT can treat 3 mice simultaneously with a homogeneous and high irradiance The medical LEF systems developed for PDT in Dermatology for the treatment of actinic keratosis demonstrate their superiority thanks to a uniform light distribution due the flexibility of LEF. Interestingly, the technology used for manufacturing LEF is very well known by the textile industry, leading to very competitive production costs. The fact that optical fibers can transmit light from 400 nm to 1200 nm allows the connection of LEF to different laser sources covering the light spectrum of all photosensitizers used for medical applications. New developments should allow to use the LEF inside cavities such as the pleural or the peritoneal cavities.","PeriodicalId":75242,"journal":{"name":"Translational biophotonics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/tbio.202000005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43979319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

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Translational biophotonics Pub Date : 2020-05-01 DOI: 10.1002/tbio.201990002

引用次数: 0

Front Cover 前盖

Translational biophotonics Pub Date : 2020-05-01 DOI: 10.1002/tbio.201970005

引用次数: 0

Photodiagnosis and photodynamic therapy 光诊断和光动力治疗

Translational biophotonics Pub Date : 2020-05-01 DOI: 10.1002/tbio.202090001

Ronald Sroka, Carsten M. Philipp

引用次数: 63

Application of 5‐aminolevulinic acid‐photodynamic therapy in common skin diseases 5-氨基乙酰丙酸光动力疗法在常见皮肤病中的应用

Translational biophotonics Pub Date : 2020-04-15 DOI: 10.1002/tbio.201900028

Lei Shi, Pei Liu, Jia Liu, Yuling Yang, Qi Chen, Yunfeng Zhang, Haiyan Zhang, Xiuli Wang

引用次数: 10

Stimulation of the oxygen consumption by photobiomodulation in the chicken embryo chorioallantoic membrane during hypoxia 光生物调节对缺氧条件下鸡胚绒毛膜尿囊膜耗氧量的影响

Translational biophotonics Pub Date : 2020-03-16 DOI: 10.1002/tbio.201900025

E. Gerelli, G. Wagnières, Jaroslava Joniová

{"title":"Stimulation of the oxygen consumption by photobiomodulation in the chicken embryo chorioallantoic membrane during hypoxia","authors":"E. Gerelli, G. Wagnières, Jaroslava Joniová","doi":"10.1002/tbio.201900025","DOIUrl":"https://doi.org/10.1002/tbio.201900025","url":null,"abstract":"The main objective of this project is to study the effects of photobiomodulation (PBM) on the oxygen consumption in the in vivo chick’s embryo chorioallantoic membrane (CAM) under hypoxia to improve understanding of the mechanisms involved in PBM therapy of various conditions, including strokes and ischemic wounds. Protoporphyrin IX (PPIX), produced endogenously after administration of aminolevulinic acid, was used to probe the oxygen partial pressure (pO 2 ) in the CAM by time-resolved spectroscopy of its delayed fluorescence. This approach enables exploring and optimizing conveniently different radiometric and spectral parameters at play in PBM. Interestingly, since PPIX is produced in the mitochondria, an organelle playing a key role in cell respiration, and then diffuses in different compartments, the pO 2 can be determined in different (sub-) cellular/tissue locations. Our results showed that PBM applied between 6 and 16 minutes (5 mW/cm 2 ) after the beginning of hypoxia with light at 730 or 820 nm sustains the oxygen consumption in the CAM for more than one hour, an effect that is not observed in control eggs. This may explain the positive effects induced by PBM in hypoxic tissues, including those that are subject to ischemia-reperfusion injuries.","PeriodicalId":75242,"journal":{"name":"Translational biophotonics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/tbio.201900025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45825430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photodynamic inactivation of antibiotic‐resistant Gram‐positive bacteria: Challenges and opportunities 抗生素耐药性革兰氏阳性菌的光动力学失活：挑战与机遇

Translational biophotonics Pub Date : 2020-03-04 DOI: 10.1002/tbio.201900030

Z. Malik

引用次数: 2