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Ejaculatio praecox: Benefit durch Botox-A-Injektion in den M. bulbospongiosus?
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-02-01 Epub Date: 2025-02-06 DOI: 10.1055/a-2321-2169
{"title":"Ejaculatio praecox: Benefit durch Botox-A-Injektion in den M. bulbospongiosus?","authors":"","doi":"10.1055/a-2321-2169","DOIUrl":"https://doi.org/10.1055/a-2321-2169","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 1","pages":"12"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enfortumab vedotin as a salvage option as 5th line therapy for metastatic urothelial bladder cancer. 作为转移性尿路上皮性膀胱癌第5线治疗的补救性选择。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-02-01 Epub Date: 2023-11-14 DOI: 10.1055/a-2148-5799
Melanie Klee, Marie Christine Roesch, Hendrik Eggers, Philipp Ivanyi, Axel S Merseburger, Mario Kramer
{"title":"Enfortumab vedotin as a salvage option as 5th line therapy for metastatic urothelial bladder cancer.","authors":"Melanie Klee, Marie Christine Roesch, Hendrik Eggers, Philipp Ivanyi, Axel S Merseburger, Mario Kramer","doi":"10.1055/a-2148-5799","DOIUrl":"10.1055/a-2148-5799","url":null,"abstract":"<p><p>A 67-year-old female patient with a muscle-invasive, non-metastatic urothelial bladder cancer (UC) (pT2 G3 cN0 cM0) developed metachronous metastases within 6 months after radical cystectomy with ileal conduit urinary diversion. After a good primary response to platinum-based chemotherapy, treatment was switched to the immune checkpoint inhibitor (ICI) pembrolizumab due to progressive disease. Subsequently the patient underwent selective internal radiotherapy (SIRT) of the liver and received vinflunine as well as a re-challenge with pembrolizumab. Two years after the initial diagnosis, rapid disease progression ultimately led to a switch to 5th line therapy with enfortumab vedotin (EV), which had only been approved in the United States at that time. The antibody-drug conjugate was well tolerated by the patient after dose reduction to 1.0 mg/ kg body weight. Simultaneous irradiation of newly occurring precardiac, hepatic and cerebral metastases were necessary. After 10 months of therapy with EV, tumour regression was observed accompanied with good symptom control. The presented case illustrates the efficacy and tolerability of EV in a heavily pre-treated patient with metastatic UC (mUC).</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"71-76"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107589973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bimodal and multimodal endoscopy of the urinary bladder in diagnosis and treatment]. [双峰和多峰膀胱内窥镜在诊断和治疗中的应用]。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-01-28 DOI: 10.1055/a-2495-8450
Malin Nientiedt, Frank Waldbillig
{"title":"[Bimodal and multimodal endoscopy of the urinary bladder in diagnosis and treatment].","authors":"Malin Nientiedt, Frank Waldbillig","doi":"10.1055/a-2495-8450","DOIUrl":"https://doi.org/10.1055/a-2495-8450","url":null,"abstract":"<p><p>White light cystoscopy is a precise instrument for the detection and treatment of papillary bladder tumors. Various additional macroscopic detection methods have been established. Some of them, especially PDD or NBI, have been shown to have an additional benefit on the recurrence rate of bladder tumors, so they should be used as part of the diagnosis and treatment when available. Other microscopic classification techniques or multimodality techniques are currently under development. Widespread use of these techniques is still pending. Newer modalities such as multi-parametric imaging or AI-assisted endoscopy promise a significant leap in innovation in the future and could ensure that real-time urological endoscopy is significantly advanced.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cobb's collar … seek and you shall find!] [柯布的项圈…寻找你就会找到！]］
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2024-12-05 DOI: 10.1055/a-2466-6115
Evi Comploj, Christian Ladurner, Armin Pycha
{"title":"[Cobb's collar … seek and you shall find!]","authors":"Evi Comploj, Christian Ladurner, Armin Pycha","doi":"10.1055/a-2466-6115","DOIUrl":"https://doi.org/10.1055/a-2466-6115","url":null,"abstract":"<p><strong>Purpose: </strong>Cobb's collar, also known as Moormann's ring, is a rare membranous stricture of the bulbar urethra. In contrast to the posterior urethral valve (PUV), Cobb's collar is not connected to the verumontanum. A simultaneous occurrence of PUV and Cobb's collar is even rarer. To the best of our knowledge, we report the third case in the literature of a child with coexistence of PUV and Cobb's collar.</p><p><strong>Case presentation: </strong>We present the case of a 3-year-old boy with a history of recurrent episodes of bladder outlet obstruction with residual urine volumes of up to 800 ml. An outward cystoscopy only revealed a bladder neck with a spastic appearance. A neuropediatric visit was unremarkable; magnetic resonance imaging (MRI) of the brain and spine was negative. After the positioning of a suprapubic catheter, cystoscopy was repeated, and a membranous stricture distal to the external sphincter - also known as Cobb's collar - was diagnosed and incised. After the procedure, the patient was able to urinate with residual volumes ranging from 40-50 ml. However, two weeks later, residual volumes increased again, and a second cystoscopy was performed. In addition to the open Cobb's collar, a PUV was detected, and both were incised with a cold hooked knife.</p><p><strong>Conclusions: </strong>The diagnosis is difficult to make unless the urologist is aware of and actively looks for these rare congenital anomalies of the urethra, which present with variable clinical manifestations and degrees of obstruction.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Operative management of penoscrotal elephantiasis]. 阴茎象皮病的手术治疗。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2024-12-04 DOI: 10.1055/a-2442-4858
Vahudin Zugor, Mustapha Addali, Benjamin Hager, David Kajaia
{"title":"[Operative management of penoscrotal elephantiasis].","authors":"Vahudin Zugor, Mustapha Addali, Benjamin Hager, David Kajaia","doi":"10.1055/a-2442-4858","DOIUrl":"https://doi.org/10.1055/a-2442-4858","url":null,"abstract":"<p><p>Enormous oedema of the male genitals, such as penoscrotal elephantiasis, is a very rare condition. It is usually a result of recurrent inflammation, trauma or malignancy, although the main cause is lymphatic filariasis. Furthermore, it is a challenging condition for both patient as well as the attending healthcare team. By elongation of the lymphatic channels, local oedema is initially created. In the further course, through fibrosis and thus deterioration of the lymphatic drainage, recurrent infections with irreversible elephantiac hard swelling and skin changes are evident. Depending upon the clinical stage, conservative or surgical treatment are suggested. Unfortunately, up to date, no evidence-based therapeutic protocol exists. Interdisciplinary cooperation among doctors, physiotherapists with active cooperation of the patient decide the success of the therapeutic outcome.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kommentar zu: ProstataCa – Extraprostatische Ausdehnung als Risikofaktor erst ab ISUP Grad 2. 评论：前列腺癌-前列腺外扩张作为ISUP 2级以上的危险因素。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2024-12-01 Epub Date: 2024-12-03 DOI: 10.1055/a-2348-7301
{"title":"Kommentar zu: ProstataCa – Extraprostatische Ausdehnung als Risikofaktor erst ab ISUP Grad 2.","authors":"","doi":"10.1055/a-2348-7301","DOIUrl":"https://doi.org/10.1055/a-2348-7301","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"55 6","pages":"503"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radikale Zystektomie: Weniger Hernien durch Netz beim Ileum-Conduit? 根治性膀胱切除术：Ileum导管网疝减少？
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2024-12-01 Epub Date: 2024-12-03 DOI: 10.1055/a-2321-2237
{"title":"Radikale Zystektomie: Weniger Hernien durch Netz beim Ileum-Conduit?","authors":"","doi":"10.1055/a-2321-2237","DOIUrl":"https://doi.org/10.1055/a-2321-2237","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"55 6","pages":"492-494"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skrotumeingriffe: Schmerzkontrolle mit Gabapentin. 用加巴喷丁控制疼痛。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2024-12-01 Epub Date: 2024-12-03 DOI: 10.1055/a-2321-2061
{"title":"Skrotumeingriffe: Schmerzkontrolle mit Gabapentin.","authors":"","doi":"10.1055/a-2321-2061","DOIUrl":"https://doi.org/10.1055/a-2321-2061","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"55 6","pages":"490"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Histopathological analysis of germ cell tumours: aspects to consider]. [生殖细胞肿瘤的组织病理学分析：需要考虑的方面]。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2024-12-01 Epub Date: 2024-09-05 DOI: 10.1055/a-2363-4744
Alexander Fichtner, Daniel Nettersheim, Felix Bremmer
{"title":"[Histopathological analysis of germ cell tumours: aspects to consider].","authors":"Alexander Fichtner, Daniel Nettersheim, Felix Bremmer","doi":"10.1055/a-2363-4744","DOIUrl":"10.1055/a-2363-4744","url":null,"abstract":"<p><p>Germ cell tumours (GCT) are the most common testicular tumours and form a heterogenous group of tumours with different biological behaviour. Based on differences regarding patient age at first manifestation, morphological characteristics and molecular changes, they are divided into three different groups of GCTs (type I-III). For treatment and prognosis, an exact histopathological analysis of an orchiectomy resection specimen is very important, including the specification of all different histological subtypes with their proportional distribution. This article describes the approach of the preparation of a resection specimen and the histopathological analysis of a testicular tumour. In addition, it describes cases in which additional tools like immunohistochemical and molecular analyses are necessary. Furthermore, the current WHO classification of testicular GCT is discussed.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"528-536"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142138995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urothelkarzinom: Urintest CxbT verringert Zystoskopien bei Mikrohämaturien. CxbT可降低膀胱癌的发病率。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2024-12-01 Epub Date: 2024-12-03 DOI: 10.1055/a-2321-2078
{"title":"Urothelkarzinom: Urintest CxbT verringert Zystoskopien bei Mikrohämaturien.","authors":"","doi":"10.1055/a-2321-2078","DOIUrl":"https://doi.org/10.1055/a-2321-2078","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"55 6","pages":"496-498"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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