The Lancet regional health. Southeast Asia最新文献

{"title":"Poor coverage of quality-adjusted antenatal care services: a population-level assessment by visit and source of antenatal care services in Bihar state of India","authors":"Rakhi Dandona , G Anil Kumar , Moutushi Majumder , Md Akbar , S Siva Prasad Dora , Lalit Dandona , ENHANCE 2020 team","doi":"10.1016/j.lansea.2023.100332","DOIUrl":"10.1016/j.lansea.2023.100332","url":null,"abstract":"<div><h3>Background</h3><p>Despite the evidence on the poor quality of antenatal care (ANC) services, significant gap remains in the understanding of quality-adjusted coverage at the population-level for each ANC visit and by the source of ANC services, and in equity in this coverage.</p></div><div><h3>Methods</h3><p>All births between July 2020 and June 2021 were listed from 261,124 households (91.5% participation) representative of the Bihar state. Mothers of all stillbirths and neonatal deaths, and of 25% random sample of livebirths who survived the neonatal period provided data on each ANC visit up to a maximum of first 4 ANC visits, including the source of ANC services and the services received (weight measurement, blood pressure checked, abdomen checked, urine sample taken, and blood sample taken). An ANC visit was deemed of quality if all of these services were received in that visit. We report the coverage of quality-adjusted ANC services (Q-ANC) for ANC visits 1–4 disaggregated by source of ANC services and wealth index (WI). Weighted proportions are reported to take into account the sampling design.</p></div><div><h3>Findings</h3><p>A total of 30,412 births were reported by 29,517 women, and 7270 (82.1%) of the 8853 eligible women participated. Overall, 19,950 unique ANC visits from 6929 women were available for analysis, of which 41.7%, 13.8% and 44.5% were at Village Health and Nutrition Day (VNHD), public facility, and with a private provider, respectively. A total of 4409 (65.3%) of the 1st ANC visits were undertaken at VHND, with the proportion of private provider ANC visits increasing significantly from ANC visit 1 to ANC visit 4 (p < 0.001). Q-ANC coverage considering all ANC visits was 20.9% (95% CI 20.7–21.2); and was 0.9% (95% CI 0.8–1.0), 29.9% (95% CI 29.2–30.7) and 36.9% (95% CI 36.5–37.4) for ANC visits in VHND, public facilities, and with private provider, respectively. Q-ANC coverage in the public facility was significantly lower in the 4th ANC visit (25.1%; 95% CI 23.4–26.9) as compared with visits 1 to 3, whereas it was the highest for 1st ANC visit with private provider (50.2%; 95% CI 49.2–51.1) and then dropped for visits 2 to 4. Irrespective of the source of ANC services, Q-ANC coverage increased significantly with increasing WI quartile for ANC visits 1 and 2, with WI quartile 3 women having significantly less coverage for ANC visit 3 compared to the rest, and no significant difference seen in the coverage of ANC 4 visit. Varied pattern of Q-ANC coverage by WI for each ANC visit was seen for public facility and private provider visits.</p></div><div><h3>Interpretation</h3><p>With only 2 of 10 ANC visits deemed of adequate quality, sustainable delivery of quality ANC services are needed for every pregnant woman through-out the pregnancy irrespective of gestation period, number of ANC visit, and source of ANC services.</p></div><div><h3>Funding</h3><p><span>The funding was provided by the India office of the Bill ","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"25 ","pages":"Article 100332"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368223001920/pdfft?md5=8428124c169ce17945297eda5c0bfa16&pid=1-s2.0-S2772368223001920-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139295140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-discharge mortality among patients hospitalised with severe acute respiratory infection, Bangladesh, 2012–2019: a prospective observational study","authors":"Md Ariful Islam ,&nbsp;Md Zakiul Hassan ,&nbsp;Mohammad Abdul Aleem ,&nbsp;Zubair Akhtar ,&nbsp;Sukanta Chowdhury ,&nbsp;Md Kaousar Ahmmed ,&nbsp;Mustafizur Rahman ,&nbsp;Mohammed Ziaur Rahman ,&nbsp;Syeda Mah-E-Muneer ,&nbsp;M Salim Uzzaman ,&nbsp;Tahmina Shirin ,&nbsp;Meerjady Sabrina Flora ,&nbsp;Mahmudur Rahman ,&nbsp;William W. Davis ,&nbsp;Eduardo Azziz-Baumgartner ,&nbsp;A. Danielle Iuliano ,&nbsp;Fahmida Chowdhury","doi":"10.1016/j.lansea.2024.100363","DOIUrl":"10.1016/j.lansea.2024.100363","url":null,"abstract":"<div><h3>Background</h3><p>Enhancing outcomes post-hospitalisation requires an understanding of predictive factors for adverse events. This study aimed to estimate post-discharge mortality rates among patients with severe acute respiratory infection (SARI) in Bangladesh, identify associated factors, and document reported causes of death.</p></div><div><h3>Methods</h3><p>From January 2012 to December 2019, we conducted follow-up calls to patients or their families 30 days after discharge to assess the status of patients with SARI. Proportions of deaths within 30 days of discharge were estimated, and a comparative analysis of demographics, clinical characteristics, and influenza illness between decedents and survivors was performed using multivariable Cox regression models.</p></div><div><h3>Findings</h3><p>Among 23,360 patients with SARI (median age: 20 years, IQR: 1.5–48, 65% male), 351 (1.5%) died during hospitalisation. Of 23,009 patients alive at discharge, 20,044 (87%) were followed, with 633 (3.2%) deaths within 30 days of discharge. In children (&lt;18 years), difficulty breathing (adjusted hazard ratio [aHR] 1.8; 95% CI 1.1–3.0), longer hospital stay (aHR 1.1; 95% CI 1.1–1.1), and heart diseases (aHR 8.5; 95% CI 3.2–23.1) were associated with higher post-discharge death risk. Among adults (≥18 years), difficulty breathing (aHR 2.3; 95% CI 1.7–3.0), chronic obstructive pulmonary disease (aHR 1.7; 95% CI 1.4–2.2), and intensive care unit admission (aHR 5.2; 95% CI 1.9–14.0) were linked to elevated post-discharge death risk. Influenza virus was detected in 13% (46/351) of in-hospital SARI deaths and 10% (65/633) of post-discharge SARI deaths.</p></div><div><h3>Interpretation</h3><p>Nearly one in twenty patients with SARI died during hospitalisation or within 1 month of discharge, with two-thirds of deaths occurring post-discharge. Seasonal influenza vaccination is recommended to mitigate influenza-associated mortality. To enhance post-discharge outcomes, hospitals should consider developing safe-discharge algorithms, reinforcing post-discharge care plans, and establishing outpatient monitoring for recently discharged patients.</p></div><div><h3>Funding</h3><p><span>Centers for Disease Control and Prevention</span> (CDC), Atlanta, Georgia, USA [<span>U01GH002259</span>].</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"25 ","pages":"Article 100363"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000131/pdfft?md5=9b3d7a808a749885a922aa911eb7a4fd&pid=1-s2.0-S2772368224000131-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140469633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequential levetiracetam and phenytoin in electroencephalographic neonatal seizures unresponsive to phenobarbital: a multicenter prospective observational study in India","authors":"Vaisakh Krishnan ,&nbsp;Vidya Ujjanappa ,&nbsp;Hemadri Vegda ,&nbsp;Manjesh K. Annayappa ,&nbsp;Pooja Wali ,&nbsp;Sudhindrashayana Fattepur ,&nbsp;Savitha Chandriah ,&nbsp;Sahana Devadas ,&nbsp;Mallesh Kariappa ,&nbsp;Veluthedath Kuzhiyil Gireeshan ,&nbsp;Ajithkumar Vellani Thamunni ,&nbsp;Paolo Montaldo ,&nbsp;Constance Burgod ,&nbsp;Reema Garegrat ,&nbsp;Pallavi Muraleedharan ,&nbsp;Stuti Pant ,&nbsp;Charles R. Newton ,&nbsp;J Helen Cross ,&nbsp;Paul Bassett ,&nbsp;Seetha Shankaran ,&nbsp;Ronit M. Pressler","doi":"10.1016/j.lansea.2024.100371","DOIUrl":"10.1016/j.lansea.2024.100371","url":null,"abstract":"<div><h3>Background</h3><p>Although levetiracetam and phenytoin are widely used antiseizure medications (ASM) in neonates, their efficacy on seizure freedom is unclear. We evaluated electroencephalographic (EEG) seizure freedom following sequential levetiracetam and phenytoin in neonatal seizures unresponsive to phenobarbital.</p></div><div><h3>Methods</h3><p>We recruited neonates born ≥35 weeks and aged &lt;72 h who had continued electrographic seizures despite phenobarbital, from three Indian hospitals, between 20 June 2020 and 31 July 2022. The neonates were treated with intravenous levetiracetam (20 mg/kg x 2 doses, second line) followed by phenytoin (20 mg/kg x 2 doses, third line) if seizures persisted. The primary outcome was complete seizure freedom, defined as an absence of seizures on EEG for at least 60 min within 40 min from the start of infusion.</p></div><div><h3>Findings</h3><p>Of the 206 neonates with continued seizures despite phenobarbital, 152 received levetiracetam with EEG. Of these one EEG was missing, 47 (31.1%) were in status epilepticus, and primary outcome data were available in 145. Seizure freedom occurred in 20 (13.8%; 95% CI 8.6%–20.5%) after levetiracetam; 16 (80.0%) responded to the first dose and 4 (20.0%) to the second dose. Of the 125 neonates with persisting seizures after levetiracetam, 114 received phenytoin under EEG monitoring. Of these, the primary outcome data were available in 104. Seizure freedom occurred in 59 (56.7%; 95% CI 46.7%–66.4%) neonates; 54 (91.5%) responded to the first dose and 5 (8.5%) to the second dose.</p></div><div><h3>Interpretation</h3><p>With the conventional doses, levetiracetam was associated with immediate EEG seizure cessation in only 14% of phenobarbital unresponsive neonatal seizures. Additional treatment with phenytoin along with levetiracetam attained seizure freedom in further 57%. Safety and efficacy of higher doses of levetiracetam should be evaluated in well-designed randomised controlled trials.</p></div><div><h3>Funding</h3><p><span>National Institute for Health and Care Research</span> (NIHR) <span>Research and Innovation for Global Health Transformation</span> (<span>NIHR200144</span>).</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"25 ","pages":"Article 100371"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000209/pdfft?md5=12ca6c3c5fb5d57550eb85fb180818fa&pid=1-s2.0-S2772368224000209-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139827736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High post discharge mortality in children of severe pneumonia in two states of Northern India","authors":"Shally Awasthi ,&nbsp;Anuj Kumar Pandey ,&nbsp;CAP Study Group","doi":"10.1016/j.lansea.2023.100334","DOIUrl":"https://doi.org/10.1016/j.lansea.2023.100334","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"25 ","pages":"Article 100334"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368223001944/pdfft?md5=3fbf539779f8ec6358d47c62ded06b56&pid=1-s2.0-S2772368223001944-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141429023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"India’s Poshan Tracker: data-driven tool for maternal and child nutrition","authors":"Lindsay M. Jaacks ,&nbsp;Ananya Awasthi ,&nbsp;Apoorva Kalra","doi":"10.1016/j.lansea.2024.100381","DOIUrl":"10.1016/j.lansea.2024.100381","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"25 ","pages":"Article 100381"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000301/pdfft?md5=b1f6db8ffa11a04e183e6e9e90fbf30c&pid=1-s2.0-S2772368224000301-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and external validation of Indian population-specific Garbhini-GA2 model for estimating gestational age in second and third trimesters","authors":"Veerendra P. Gadekar ,&nbsp;Nikhita Damaraju ,&nbsp;Ashley Xavier ,&nbsp;Shambo Basu Thakur ,&nbsp;Ramya Vijayram ,&nbsp;Bapu Koundinya Desiraju ,&nbsp;Sumit Misra","doi":"10.1016/j.lansea.2024.100362","DOIUrl":"10.1016/j.lansea.2024.100362","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;p&gt;A large proportion of pregnant women in lower and middle-income countries (LMIC) seek their first antenatal care after 14 weeks of gestation. While the last menstrual period (LMP) is still the most prevalent method of determining gestational age (GA), ultrasound-based foetal biometry is considered more accurate in the second and third trimesters. In LMIC settings, the Hadlock formula, originally developed using data from a small Caucasian population, is widely used for estimating GA and foetal weight worldwide as the pre-programmed formula in ultrasound machines. This approach can lead to inaccuracies when estimating GA in a diverse population. Therefore, this study aimed to develop a population-specific model for estimating GA in the late trimesters that was as accurate as the GA estimation in the first trimester, using data from GARBH-Ini, a pregnancy cohort in a North Indian district hospital, and subsequently validate the model in an independent cohort in South India.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Data obtained by longitudinal ultrasonography across all trimesters of pregnancy was used to develop and validate GA models for the second and third trimesters. The gold standard for GA estimation in the first trimester was determined using ultrasonography. The Garbhini-GA2, a polynomial regression model, was developed using the genetic algorithm-based method, showcasing the best performance among the models considered. This model incorporated three of the five routinely measured ultrasonographic parameters during the second and third trimesters. To assess its performance, the Garbhini-GA2 model was compared against the Hadlock and INTERGROWTH-21st models using both the TEST set (N = 1493) from the GARBH-Ini cohort and an independent VALIDATION dataset (N = 948) from the Christian Medical College (CMC), Vellore cohort. Evaluation metrics, including root-mean-squared error, bias, and preterm birth (PTB) rates, were utilised to comprehensively assess the model's accuracy and reliability.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Findings&lt;/h3&gt;&lt;p&gt;With first trimester GA dating as the baseline, Garbhini-GA2 reduced the GA estimation median error by more than three times compared to the Hadlock formula. Further, the PTB rate estimated using Garbhini-GA2 was more accurate when compared to the INTERGROWTH-21st and Hadlock formulae, which overestimated the rate by 22.47% and 58.91%, respectively.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Interpretation&lt;/h3&gt;&lt;p&gt;The Garbhini-GA2 is the first late-trimester GA estimation model to be developed and validated using Indian population data. Its higher accuracy in GA estimation, comparable to GA estimation in the first trimester and PTB classification, underscores the significance of deploying population-specific GA formulae to enhance antenatal care.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Funding&lt;/h3&gt;&lt;p&gt;The GARBH-Ini cohort study was funded by the &lt;span&gt;Department of Biotechnology&lt;/span&gt;, &lt;span&gt;Government of India&lt;/span&gt; (BT/PR9983/MED/97/194/2013). The u","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"25 ","pages":"Article 100362"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277236822400012X/pdfft?md5=46843cfb32db18f8eee480e12acaffb4&pid=1-s2.0-S277236822400012X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140468710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of COVID-19 on essential service provision for reproductive, maternal, neonatal, and child health in the Southeast Asia region: a systematic review","authors":"Thomas Gadsden ,&nbsp;Tushar Sood ,&nbsp;Parnika Purwar ,&nbsp;David Peiris ,&nbsp;Devaki Nambiar ,&nbsp;Laura E. Downey","doi":"10.1016/j.lansea.2024.100357","DOIUrl":"10.1016/j.lansea.2024.100357","url":null,"abstract":"<div><h3>Background</h3><p>There is increasing evidence that the COVID-19 pandemic has impacted adversely on the provision of essential health services globally. The Southeast Asia region (SEAR) has experienced extremely high rates of COVID-19 infection, with potential adverse impacts on provision of reproductive, maternal, neonatal, and child health (RMNCH) services.</p></div><div><h3>Methods</h3><p>We conducted a systematic literature review of quantitative evidence to characterise the impact of COVID-19 on the provision of essential RMNCH services across the SEAR. Studies published between December 2019 and May 2022 were included in the study. The quality of studies was evaluated using the Joanna Briggs Institute Critical Appraisal Checklist.</p></div><div><h3>Findings</h3><p>We reviewed 1924 studies and analysed data from 20 peer-reviewed studies and three reports documenting quantitative pre-post estimates of RMNCH service disruption because of the COVID-19 pandemic. Eleven studies were of low methodological quality, in addition to seven and five studies of moderate and high methodological qualities respectively. Six countries in the region were represented in the included studies: India (11 studies), Bangladesh (4), Nepal (3), Sri Lanka (1), Bhutan (1) and Myanmar (1). These countries demonstrated a wide reduction in antenatal care services (−1.6% to −69.6%), facility-based deliveries (−2.3% to −52.4%), child immunisation provision (−13.5% to −87.7%), emergency obstetric care (+4.0% to −76.6%), and family planning services (−4.2% to −100%).</p></div><div><h3>Interpretation</h3><p>There have been large COVID-19 pandemic related disruptions for a wide range of RMNCH essential health service indicators in several SEAR countries. Notably, we found a higher level of service disruption than the WHO PULSE survey estimates. If left unaddressed, such disruptions may set back hard-fought gains in RMNCH outcomes across the region. The absence of studies in five SEAR countries is a priority evidence gap that needs addressing to better inform policies for service protection.</p></div><div><h3>Funding</h3><p><span>WHO</span> Sri Lanka Country Office.</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"25 ","pages":"Article 100357"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000076/pdfft?md5=e0ce71550122623e5aa5b3b9c11c3541&pid=1-s2.0-S2772368224000076-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139812585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a large-scale alcohol ban on population-level alcohol intake, weight, blood pressure, blood glucose, and domestic violence in India: a quasi-experimental population-based study","authors":"Suman Chakrabarti ,&nbsp;Anita Christopher ,&nbsp;Samuel Scott ,&nbsp;Avinash Kishore ,&nbsp;Phuong Hong Nguyen","doi":"10.1016/j.lansea.2024.100427","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100427","url":null,"abstract":"<div><h3>Background</h3><p>Globally, alcohol consumption is a leading risk factor for deaths and disability and a causal factor in over 200 diseases, injuries, and health conditions. In April 2016, the manufacture, transport, sale, and consumption of alcohol was banned in Bihar, a populous Indian state. We sought to estimate the impacts of this ban on health outcomes and domestic violence.</p></div><div><h3>Methods</h3><p>Data from the Indian National Family Health Surveys (2005–06, 2015–16, 2019–21), Annual Health Survey (2013), and District Level Household Survey (2012), were used to conduct difference-in-differences (DID) analysis, comparing Bihar (n = 10,733 men, n = 88,188 women) and neighbouring states (n = 38,674 men, n = 284,820 women) before and after the ban. Outcomes included frequent (daily or weekly) alcohol consumption, underweight, obesity, hypertension, diabetes, and intimate partner violence. A triple difference model adding male–female interaction to the DID model was also estimated. Attributable averted cases were calculated to estimate the impact of the ban.</p></div><div><h3>Findings</h3><p>Across all models, the ban led to reduced frequent alcohol consumption (DID: −7.1 percentage points (pp) (95% CI −9.6pp, −4.6pp), lower overweight/obesity (−5.6pp (−8.9, −2.2) among males, and reduced experiences of emotional (−4.8pp (−8.2pp, −1.4pp) and sexual (−5.5pp (−8.7pp, −2.3pp) violence among females. The ban prevented approximately 2.4 million cases of daily/weekly alcohol consumption and 1.8 million cases of overweight/obesity among males, and 2.1 million cases of intimate partner violence among females.</p></div><div><h3>Interpretation</h3><p>Strict alcohol regulation policies may yield significant population level health benefits for frequent drinkers and many victims of intimate partner violence.</p></div><div><h3>Funding</h3><p>No funding was received for this work.</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"26 ","pages":"Article 100427"},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000775/pdfft?md5=1d9245e6cd964cb24ba23b696bb38e61&pid=1-s2.0-S2772368224000775-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141090284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The recent WHO guideline on acute malnutrition overestimates therapeutic energy requirement","authors":"Harshpal Singh Sachdev ,&nbsp;Anura V. Kurpad","doi":"10.1016/j.lansea.2024.100419","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100419","url":null,"abstract":"<div><p>The World Health Organization has recently updated the guideline on the prevention and management of wasting and nutritional oedema (acute malnutrition) in infants and children under 5 years. Apart from differences with regard to the nutritional framework that defines the quantity of energy required as Ready-to-Use Therapeutic Food (RUTF) for the outpatient treatment of severe wasting and/or nutritional oedema, there are also important gaps in the practical guidance. Instead of the recommended energy intake of 150–185 kcal/kg/day, our alternative calculations indicate the requirement to be only 105–120 kcal/kg/day. If true, the implementation of such caloric overfeeding can have adverse consequences. Gaps in practical guidance also need to be addressed, including the timing of transition to home-based diets, maximal duration of therapeutic feeding, especially in non-responders (∼50% in South Asia), and the role of augmented home foods as the primary therapeutic food option.</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"25 ","pages":"Article 100419"},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000696/pdfft?md5=db7d050841b7093ec7c172db992d801c&pid=1-s2.0-S2772368224000696-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141073412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Look-alike, sound-alike (LASA) drugs in India","authors":"Murali Neelakantan ,&nbsp;Parth Sharma ,&nbsp;Ashish Kulkarni","doi":"10.1016/j.lansea.2024.100425","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100425","url":null,"abstract":"<div><p>Poor drug regulation in India is not a recent problem. The Indian drug market is full of look-alike, sound-alike (LASA) drugs which have not yet caught the attention of the media or the medical community. This viewpoint highlights the problem of LASA drugs and poor prescription practices and proposes solutions for involving all stakeholders in this unaddressed issue which is a huge public health problem in India.</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"26 ","pages":"Article 100425"},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000751/pdfft?md5=2dc9cc471cf261ee63637fa3eb39828b&pid=1-s2.0-S2772368224000751-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}