The Lancet regional health. Southeast Asia最新文献

{"title":"Addressing unmet needs of adolescents to prevent unintended pregnancy in the Asia Pacific region","authors":"Sumita Banerjee , Bunyarit Sukrat , Ketkesone Phrasisombath , Marijuzca Y. Nicolas , Bibek Kumar Lal , Sadia Rahman , Marie Habito , Elissa Kennedy , Stephen Bell","doi":"10.1016/j.lansea.2025.100693","DOIUrl":"10.1016/j.lansea.2025.100693","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100693"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological issue in a dental neuromelioidosis outbreak investigation—authors’ reply","authors":"Angel Miraclin Thirugnanakumar , Prabu Rajkumar , Karthik Gunasekaran , Manickam Ponnaiah , Girish Kumar Chethrapilly Purushothaman , Balaji Veeraraghavan , Manoj Murhekar","doi":"10.1016/j.lansea.2025.100659","DOIUrl":"10.1016/j.lansea.2025.100659","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100659"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145790022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health and its expanding role in systemic disease, cancer outcomes, and public health","authors":"Vaibhav Sahni, Abhishek Shankar","doi":"10.1016/j.lansea.2025.100627","DOIUrl":"10.1016/j.lansea.2025.100627","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100627"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145790023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening WHO's South-East Asia Regional Office: from crisis to opportunity?","authors":"Swarup Sarkar , Diah Saminarsih , J.V.R. Prasada Rao , Kent Buse","doi":"10.1016/j.lansea.2025.100684","DOIUrl":"10.1016/j.lansea.2025.100684","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100684"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145790025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nafithromycin in CABP: promise and precaution","authors":"Nitin Gupta , Adil Rashid Khan , Praveen Kumar Tirlangi","doi":"10.1016/j.lansea.2025.100692","DOIUrl":"10.1016/j.lansea.2025.100692","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100692"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145529091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The domino effect: projecting the effects of US funding cuts to health aid in the global south","authors":"Rechel Shrisunder, Dwight Figueiredo","doi":"10.1016/j.lansea.2025.100700","DOIUrl":"10.1016/j.lansea.2025.100700","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100700"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive primary health care for cost-effective scale-up of depression screening in India: an economic modelling study","authors":"Neha Purohit ,&nbsp;Shubh Mohan Singh ,&nbsp;Girish N. Rao ,&nbsp;Kathirvel Soundappan ,&nbsp;Atul Kotwal ,&nbsp;Shankar Prinja","doi":"10.1016/j.lansea.2025.100701","DOIUrl":"10.1016/j.lansea.2025.100701","url":null,"abstract":"<div><h3>Background</h3><div>The Government of India envisions integrating population-based depression screening within the framework of comprehensive primary health care. This study assesses the economic impact and cost-utility of implementing universal depression screening for different age groups (≥30 years and ≥20 years) compared to the current practice of opportunistic diagnosis and management of symptomatic patients.</div></div><div><h3>Methods</h3><div>A hybrid model comprising of a decision tree and Markov model was developed for economic evaluation. The input parameters were acquired through comprehensive literature search, stakeholder consultations, analysis of the data from National Mental Health Survey, and the National Sample Survey, besides primary data collected from 259 patients for quality of life. The analysis was performed from both abridged societal (consideration of direct costs) and societal perspective (consideration of direct as well as indirect costs). In line with Indian economic evaluation standards, a screening strategy was deemed cost-effective if its incremental cost-utility ratio (ICUR) was below the per capita gross domestic product (GDP) threshold of ₹1,71,498 ($2182).</div></div><div><h3>Findings</h3><div>The gain in QALYs per person from universal screening ranged from 0·0273 (0·0265–0·0281) to 0·0295 (0·0287–0·0303), depending on the target age group. The program is expected to generate net savings of ₹291 billion ($3·7 billion) to ₹482 billion ($6·1 billion), equivalent to 0·19% to 0·32% of GDP. Furthermore, the ICURs were below the threshold, with ≥20 years aged cohort screening (₹43,995, $620) being more cost-effective than the screening in ≥30 years aged population (₹48,746, $560) from the abridged societal perspective. However, the program ceases to yield positive net health benefits if the sensitivity of the PHQ-2 decreases to 26%, or if the combined sensitivity of the sequential PHQ-2 and PHQ-9 approach falls below 35%. The intervention is likely to result in cost savings if at least 60% of patients seeking treatment after screening use public health facilities.</div></div><div><h3>Interpretation</h3><div>Integrating depression screening and management into the government primary healthcare system provides substantial public health and economic benefits, supporting the case for a PHC-oriented health system. Expanding coverage to individuals aged 20 years and above, along with ensuring high diagnostic accuracy through quality training and supportive supervision, will be key to sustaining and maximizing the programme's impact.</div></div><div><h3>Funding</h3><div>The study was supported by funding from the <span>Department of Health Research</span>, <span>Ministry of Health and Family Welfare</span>, <span>Government of India</span></div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100701"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145694091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening student mental health support systems in India: reflections on the Supreme Court's landmark guidelines","authors":"Seema Mehrotra ,&nbsp;Lakshmi Vijayakumar","doi":"10.1016/j.lansea.2025.100698","DOIUrl":"10.1016/j.lansea.2025.100698","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100698"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer-specific thresholds of treatment initiation delay and assessment of their confounding variables: authors' reply","authors":"Jyoti Dixit ,&nbsp;Nidhi Gupta ,&nbsp;Pritam Halder ,&nbsp;Shankar Prinja","doi":"10.1016/j.lansea.2025.100675","DOIUrl":"10.1016/j.lansea.2025.100675","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100675"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concerns on construct validity and contamination in the Lay-CARE study — authors’ reply","authors":"Tawanchai Jirapramukpitak ,&nbsp;Suttha Supanya","doi":"10.1016/j.lansea.2025.100655","DOIUrl":"10.1016/j.lansea.2025.100655","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"43 ","pages":"Article 100655"},"PeriodicalIF":6.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145790036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}