The Lancet regional health. Southeast Asia最新文献

{"title":"Estimating the potential health and economic impacts of new tuberculosis vaccines under varying delivery strategies in Delhi and Gujarat, India: a modelling study","authors":"Rebecca A. Clark ,&nbsp;Allison Portnoy ,&nbsp;Chathika K. Weerasuriya ,&nbsp;Tom Sumner ,&nbsp;Roel Bakker ,&nbsp;Rebecca C. Harris ,&nbsp;Kirankumar Rade ,&nbsp;Sanjay Kumar Mattoo ,&nbsp;Dheeraj Tumu ,&nbsp;Nicolas A. Menzies ,&nbsp;Richard G. White","doi":"10.1016/j.lansea.2024.100424","DOIUrl":"10.1016/j.lansea.2024.100424","url":null,"abstract":"<div><h3>Background</h3><div>India has the largest tuberculosis burden, but the all-age prevalence in 2021 ranged from 747/100,000 in Delhi to 137/100,000 in Gujarat. No modelling studies have compared the potential impact of new tuberculosis vaccines in regions with differing disease and infection prevalence.</div></div><div><h3>Methods</h3><div>We used modelling to simulate hypothetical scenarios of introducing M72/AS01_E (with 50% efficacy to prevent disease) and BCG-revaccination (with 45% efficacy to prevent infection) in Delhi and Gujarat.</div></div><div><h3>Findings</h3><div>The hypothetical M72/AS01_E scenario could avert 16.0% of cases and 14.4% of deaths in Delhi, and 8.5% of cases and 7.6% of deaths in Gujarat between 2025 and 2050. The hypothetical BCG-revaccination scenario could avert 8.8% of cases and 8.3% of deaths in Delhi, and 5.1% of cases and 4.8% of deaths in Gujarat between 2025 and 2050.</div></div><div><h3>Interpretation</h3><div>Additional trials for both vaccines are underway, which will provide further evidence on the vaccine efficacy and narrow the range of uncertainty on the estimates.</div></div><div><h3>Funding</h3><div><span>Bill &amp; Melinda Gates Foundation</span> (INV-001754).</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"31 ","pages":"Article 100424"},"PeriodicalIF":5.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-disaggregated patterns in tuberculosis treatment coverage and outcomes among a nationally representative sample of deaths in India: 2019–2022","authors":"Rakhi Dandona ,&nbsp;G Anil Kumar ,&nbsp;S Siva Prasad Dora ,&nbsp;Md Akbar ,&nbsp;Kultar Singh ,&nbsp;Sibin George ,&nbsp;Moutushi Majumder ,&nbsp;Navin Kumar ,&nbsp;Rajendra P. Joshi ,&nbsp;Mrigen Deka ,&nbsp;Dimple Panchal ,&nbsp;Venkatesh Roddawar ,&nbsp;Amar Shah ,&nbsp;Vikas Choudhary ,&nbsp;Yogesh N. Patel ,&nbsp;Bhavin Vadera ,&nbsp;Kiran Rade ,&nbsp;Lalit Dandona ,&nbsp;Raghuram Rao","doi":"10.1016/j.lansea.2024.100448","DOIUrl":"10.1016/j.lansea.2024.100448","url":null,"abstract":"<div><h3>Background</h3><div>We report on TB treatment coverage and outcomes by sex among a nationally representative sample of deaths in the background of the national framework for a gender-responsive approach to TB adopted by India.</div></div><div><h3>Methods</h3><div>Detailed interviews were undertaken for a nationally representative sample of deaths of all ages between 2019 and 2022 from the adult most knowledgeable about the deceased. Details about TB treatment were documented for females and males for whom history of TB diagnosis ever.</div></div><div><h3>Findings</h3><div>Detailed data were available for 26,957 (92.1% participation) deaths. The prevalence of TB diagnosis ever was 2.9% (95% CI 2.6–3.2) and 5.8% (95% CI 5.4–6.1) among females and males, respectively. TB treatment coverage was similar for females (81.4%; 95% CI 76.7–85.3) and males (82.4%; 95% CI 79.8–84.7). TB treatment coverage was significantly lower for males with TB diagnosis in years 2021 and 2022 as compared to those diagnosed in 2019 (−12.1%; 95% CI −22.7 to −1.5). A similar proportion of females (55%) and males (58.9%) were on TB treatment at the time of death, had completed TB treatment (39.3% females and 35% males, and had discontinued TB treatment (5.3% females and 5.2% males); significant variation in treatment status was seen by age and state for both, and by wealth index quartile for males. Majority took TB treatment from public sector (females 72.9% and males 76.0%).</div></div><div><h3>Interpretation</h3><div>The sex-disaggregated findings from this nationally representative sample of deaths are a value-add to effectively address TB in India as majority of such understanding towards gender-responsive strategies is available from those who are alive.</div></div><div><h3>Funding</h3><div><span>United States Agency for International Development</span> (USAID).</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"31 ","pages":"Article 100448"},"PeriodicalIF":5.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141716128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trajectories and social determinants of child cognitive development: a prospective cohort study from infancy through middle childhood in Dhaka, Bangladesh","authors":"Viviane Valdes ,&nbsp;Eileen F. Sullivan ,&nbsp;Fahmida Tofail ,&nbsp;Lisa M. Thompson ,&nbsp;Shahria H. Kakon ,&nbsp;Talat Shama ,&nbsp;Rashidul Haque ,&nbsp;Charles A. Nelson","doi":"10.1016/j.lansea.2024.100511","DOIUrl":"10.1016/j.lansea.2024.100511","url":null,"abstract":"<div><h3>Background</h3><div>Over a third of children globally do not meet their developmental potential, and children living in low and middle-income countries (LMICs) are most vulnerable. Understanding the contextual factors that influence cognitive development for children in LMICs is crucial to inform and develop interventions. We sought to characterize developmental trajectories of cognition in Bangladeshi children and identify salient social determinants.</div></div><div><h3>Methods</h3><div>We used a longitudinal design and included 542 children living in Dhaka, Bangladesh. Social determinants (maternal and paternal education, housing risks, household assets, and food security) were assessed at baseline visits using a combination of oral interviews and home assessments. Cognitive development was assessed at 6 months, 2, 3, 4, 5, and 7 years. A total of 1397 cognitive assessments were completed across all participants. Growth curve models and mixed effect models were used.</div></div><div><h3>Findings</h3><div>In children living above the poverty line, there was increasing deviation from expected cognitive scores from 6 months to 2 years (−12.85, <em>p</em> &lt; 0.001) with stable scores from 2 to 7 years. For those below the poverty line, there were widening disparities from expectations in scores from 6 months to 4 years (−24.58, <em>p</em> &lt; 0.001) with stable scores from 4 to 7 years. Higher levels of maternal education (<em>t</em> = 2.22, <em>p</em> = 0.03) and more food security (<em>t</em> = 4.48, <em>p</em> &lt; 0.001) were protective for cognition longitudinally. Interaction effects between poverty level and maternal education and food security respectively were observed.</div></div><div><h3>Interpretation</h3><div>Cognitive development trajectories showed increasing disparities from expectations in the first two years of life, with more pronounced and lasting effects through 4 years for children below the poverty line. Maternal education and food security had promotive/protective effects on longitudinal cognitive development scores for the full sample. Maternal education and food security had stronger effects on cognitive development for children living below the poverty line compared to those living above the poverty line.</div></div><div><h3>Funding</h3><div>Funding for the study was provided by a grant from the <span>Bill and Melinda Gates Foundation</span> (OPP1111625) to CAN.</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"32 ","pages":"Article 100511"},"PeriodicalIF":5.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying clustering of cholera cases using geospatial analysis in Kolkata and surrounding districts: data from patients at tertiary care referral hospitals","authors":"Rounik Talukdar ,&nbsp;Suman Kanungo ,&nbsp;Kei Kitahara ,&nbsp;Goutam Chowdhury ,&nbsp;Debmalya Mitra ,&nbsp;Asish Kumar Mukhopadhyay ,&nbsp;Alok Kumar Deb ,&nbsp;Pallavi Indwar ,&nbsp;Biswanath Sharma Sarkar ,&nbsp;Sandip Samanta ,&nbsp;Basilua Andre Muzembo ,&nbsp;Ayumu Ohno ,&nbsp;Shin-ichi Miyoshi ,&nbsp;Shanta Dutta","doi":"10.1016/j.lansea.2024.100510","DOIUrl":"10.1016/j.lansea.2024.100510","url":null,"abstract":"<div><h3>Background</h3><div>Cholera cases have increased globally across the Eastern Mediterranean, Africa, Southeast Asia, and parts of Europe since early 2024. This study aims to identify cholera hotspots and understand the spatial distribution of cholera in Kolkata and surrounding regions, a key cholera reservoir. Additionally, we examine sociodemographic factors and aspects related to water, sanitation, and hygiene (WASH).</div></div><div><h3>Methods</h3><div>Cholera clusters were detected using kernel density estimation and spatial autocorrelation through Global Moran’s-I statistics, with local cluster patterns examined using Local Moran’s-I statistics. Cholera cases from August 2021 to December 2023, treated at two tertiary care facilities in Kolkata: Infectious Diseases and Beleghata General Hospital and Dr. B C Roy Post Graduate Institute of Paediatric Sciences Hospital were included. Additionally, through a case–control study, 196 culture-confirmed cholera cases and 764 age/sex-matched neighborhood controls were enrolled, to investigate cholera risk factors.</div></div><div><h3>Findings</h3><div>Spatial analysis revealed a concentration of 196 cholera cases in Kolkata and its surrounding regions of Howrah, Hooghly, and North and South 24 Parganas. Hotspot analysis showed significant clustering in several Kolkata wards (31, 33, 56, 46, 57, 58, 59, 61, 66, 71, and 107), particularly in the northern, central, and east Kolkata wetlands areas (Global Moran’s I statistic = 0.14, p &lt; 0.001). These clusters had proximity between cases, with a median distance of 187.7 m, and 25.5% of cases as close as 73.9 m apart, suggesting localized transmission. Hotspots were identified with an average distance of 1600 m between them. Local Moran’s I analysis found dense “high–high” clusters in these areas (p &lt; 0.01), with a mean Moran’s I index of 0.3, (range 0.1–4.6). The case–control study revealed that males were more likely to contract cholera, with an adjusted odds ratio of 2.4 (p &lt; 0.01). There was no significant association found between cholera infection and sociodemographic factors or various WASH practices.</div></div><div><h3>Interpretation</h3><div>The findings emphasize the importance of targeted interventions, especially in identified hotspots, to mitigate cholera transmission. Addressing Socio-economic, and environmental factors especially improvement in WASH practices may further enhance prevention effects.</div></div><div><h3>Funding</h3><div>The author KK, received funding from the program of the <span>Japan Initiative</span> for Global Research Network on Infectious Diseases, (grant id: <span><span>JP23wm0125004</span></span>), from the <span>Ministry of Education, Culture, Sports, Science and Technology</span> in Japan, and <span>Japan Agency for Medical Research and Development</span>.</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"31 ","pages":"Article 100510"},"PeriodicalIF":5.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142705593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotypes of South Asian patients with atrial fibrillation and holistic integrated care management: cluster analysis of data from KERALA-AF Registry","authors":"Yang Chen ,&nbsp;Bi Huang ,&nbsp;Peter Calvert ,&nbsp;Yang Liu ,&nbsp;Ying Gue ,&nbsp;Dhiraj Gupta ,&nbsp;Garry McDowell ,&nbsp;Jinbert Lordson Azariah ,&nbsp;Narayanan Namboodiri ,&nbsp;Govindan Unni ,&nbsp;Jayagopal Pathiyil Balagopalan ,&nbsp;Gregory Yoke Hong Lip ,&nbsp;Bahuleyan Charantharayil Gopalan","doi":"10.1016/j.lansea.2024.100507","DOIUrl":"10.1016/j.lansea.2024.100507","url":null,"abstract":"<div><h3>Background</h3><div>Patients with atrial fibrillation (AF) frequently experience multimorbidity. Cluster analysis, a machine learning method for classifying patients with similar phenotypes, has not yet been used in South Asian AF patients.</div></div><div><h3>Methods</h3><div>The Kerala Atrial Fibrillation Registry is a prospective multicentre cohort study in Kerala, India, and the largest prospective AF registry in South Asia. Hierarchical clustering was used to identify different phenotypic clusters. Outcomes were all-cause mortality, major adverse cardiovascular events (MACE), and composite bleeding events within one-year follow-up.</div></div><div><h3>Findings</h3><div>3348 patients were included (median age 65.0 [56.0–74.0] years; 48.8% male; median CHA₂DS₂-VASc 3.0 [2.0–4.0]). Five clusters were identified. Cluster 1: patients aged ≤65 years with rheumatic conditions; Cluster 2: patients aged &gt;65 years with multi-comorbidities, suggestive of cardiovascular-kidney-metabolic syndrome; Cluster 3: patients aged ≤65 years with fewer comorbidities; Cluster 4: heart failure patients with multiple comorbidities; Cluster 5: male patients with lifestyle-related risk factors. Cluster 1, 2 and 4 had significantly higher MACE risk compared to Cluster 3 (Cluster 1: OR 1.36, 95% CI 1.08–1.71; Cluster 2: OR 1.79, 95% CI 1.42–2.25; Cluster 4: OR 1.76, 95% CI 1.31–2.36). The results for other outcomes were similar. Atrial fibrillation Better Care (ABC) pathway in the whole cohort was low (10.1%), especially in Cluster 4 (1.9%). Overall adherence to the ABC pathway was associated with reduced all-cause mortality (OR 0.26, 95% CI 0.15–0.46) and MACE (OR 0.45, 95% CI 0.31–0.46), similar trends were evident in different clusters.</div></div><div><h3>Interpretation</h3><div>Cluster analysis identified distinct phenotypes with implications for outcomes. There was poor ABC pathway adherence overall, but adherence to such integrated care was associated with improved outcomes.</div></div><div><h3>Funding</h3><div>Kerala Chapter of <span>Cardiological Society of India</span>.</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"31 ","pages":"Article 100507"},"PeriodicalIF":5.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring sex toy use among 18–45-year-old Indian adults: insights from a nationwide online survey","authors":"Pauras Mhatre ,&nbsp;Antara Agrawal ,&nbsp;Pratham Agrawal ,&nbsp;Gaurang Narayan ,&nbsp;Priyanka Kataria ,&nbsp;Pragati Rathod ,&nbsp;Sarita Wadhva","doi":"10.1016/j.lansea.2024.100508","DOIUrl":"10.1016/j.lansea.2024.100508","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"32 ","pages":"Article 100508"},"PeriodicalIF":5.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small-area variation in child under-vaccination in India: a multilevel analysis of cross-sectional data from 36 states and Union Territories, 707 districts, and 22,349 small-area clusters","authors":"Mira Johri ,&nbsp;Sunil Rajpal ,&nbsp;Rockli Kim ,&nbsp;S.V. Subramanian","doi":"10.1016/j.lansea.2024.100504","DOIUrl":"10.1016/j.lansea.2024.100504","url":null,"abstract":"<div><h3>Background</h3><div>India has made exceptional advances in child immunisation, but subnational inequities in vaccination coverage impede attainment of key programmatic goals. Our study provides an up-to-date national portrait of local variations in child vaccination using a comprehensive set of indicators relevant to routine immunisation.</div></div><div><h3>Methods</h3><div>Indicators representing unvaccinated (zero-dose) children, incomplete basic immunisation, and vulnerability to measles and polio, were constructed from India’s 2019–2021 National Family Health Survey. We used four-level random effects logistic regression models to partition the total outcome variation over state, district and cluster levels, and produce precision-weighted estimates of prevalence across clusters. District-level prevalence and within-district variation using standard deviation measures were derived for each outcome. Boxplots graphically summarised the distribution of precision-weighted mean cluster prevalence by state.</div></div><div><h3>Findings</h3><div>The analysis included 87,622 children aged 12–36 months. Clusters accounted for 67.6% (var: 1.36; SE: 0.127) of the variation among zero-dose children, and more than 50% for all indicators. Districts with a higher prevalence of under-vaccination tended to have higher within-district heterogeneity, interpretable as greater within-district child vaccination inequities. For vaccines administered in the first year of life, the northeastern states and Uttar Pradesh had the highest median under-vaccination. Despite India’s high aggregate vaccine coverage, the distribution of small-area (cluster) mean prevalence highlighted pockets of low coverage in most states, suggesting ongoing vulnerability to measles and polio.</div></div><div><h3>Interpretation</h3><div>Achieving India’s vaccination goals requires a strategic shift towards identification and targeting of low-immunity clusters at the sub-district level.</div></div><div><h3>Funding</h3><div><span>Canadian Institutes of Health Research</span>.</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"32 ","pages":"Article 100504"},"PeriodicalIF":5.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Road traffic injuries in Southeast Asia: making journeys safer","authors":"The Lancet Regional Health – Southeast Asia","doi":"10.1016/j.lansea.2024.100506","DOIUrl":"10.1016/j.lansea.2024.100506","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"30 ","pages":"Article 100506"},"PeriodicalIF":5.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zainab (Lily): a beacon of hope","authors":"Ashfeen Aribea,&nbsp;M. Saiful Huq","doi":"10.1016/j.lansea.2024.100490","DOIUrl":"10.1016/j.lansea.2024.100490","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"30 ","pages":"Article 100490"},"PeriodicalIF":5.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One health intervention for the control and elimination of scrub typhus, anthrax, and brucellosis in Southeast Asia: a systematic review","authors":"Shishirendu Ghosal ,&nbsp;Rachita Pradhan ,&nbsp;Sneha Singh ,&nbsp;Anoop Velayudhan ,&nbsp;Sushmita Kerketta ,&nbsp;Debaprasad Parai ,&nbsp;Hari Ram Choudhary ,&nbsp;Matrujyoti Pattnaik ,&nbsp;Debdutta Bhattacharya ,&nbsp;Sanghamitra Pati","doi":"10.1016/j.lansea.2024.100503","DOIUrl":"10.1016/j.lansea.2024.100503","url":null,"abstract":"<div><div>The “One Health” (OH) approach, introduced in 2004, integrates human, animal, and environmental health to address emerging and re-emerging diseases. This study evaluates OH strategies used by southeast Asian countries for brucellosis, anthrax, and scrub typhus. We systematically searched Medline, EMBASE, ProQuest, and EBSCO-CINHL up to May 11, 2023, screened 711 articles, and included ten studies (five on brucellosis, four on anthrax, and two on scrub typhus). Key strategies identified included intersectoral collaboration, vaccination initiatives, and comprehensive surveillance systems for both humans and animals. Additional efforts were noted in improving health infrastructure and implementing preventive measures. The review underscores that although some progress has been made, a more integrated OH approach is crucial for effective prevention and management of zoonotic diseases in southeast Asia, highlighting the need for enhanced collaboration and coordinated efforts across sectors.</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"30 ","pages":"Article 100503"},"PeriodicalIF":5.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}