The Lancet regional health. Southeast Asia最新文献

{"title":"Minimum service standards assessment tool and the hospital strengthening program: a novel first step towards the quality improvement of Nepal’s national hospital system","authors":"Rita Pokhrel ,&nbsp;Abigail Knoble ,&nbsp;Pratibha Gautam ,&nbsp;Mohammad Kashim Shah ,&nbsp;Pravin Paudel ,&nbsp;Archana Amatya ,&nbsp;Madan Kumar Upadhyaya ,&nbsp;Ruma Rajbhandari","doi":"10.1016/j.lansea.2025.100548","DOIUrl":"10.1016/j.lansea.2025.100548","url":null,"abstract":"<div><div>District hospitals in Nepal, as in other Low- and Lower - Middle Income Countries (LLMICs), struggle to provide quality care due to inadequate investments in equipment, human resources, and hospital infrastructure. To address these challenges, under the leadership of the Ministry of Health and Population (MoHP), Nick Simons Institute (NSI) developed and implemented the novel Minimum Service Standards (MSS) assessment tool in close partnership with the Government of Nepal. The MSS tool routinely assesses a hospital’s readiness to provide mandated care and identify gaps, which are then closed via a small annual grant to the health facility, together providing the knowledge and resources to improve hospital readiness and service availability. Since its inception in 2014, the program has expanded to 130 government hospitals as of April 2024. The program provides a blueprint for hospitals to pursue excellence and has tracked and motivated substantial improvements in services since 2014, such as basic laboratory investigations (+46%), cesarean sections (+40%), and spinal anesthesia (+32%). The program has impacted healthcare policy due to the close collaboration with the MoHP, influencing budget allocation, insurance payments, and hospital upgrade criteria, cementing its sustainability and long term impact.</div></div><div><h3>Funding</h3><div>No external funding</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100548"},"PeriodicalIF":5.0,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143463989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community mobilisation and incentivisation as a pathway to sustainable TB control","authors":"Inayat Ali","doi":"10.1016/j.lansea.2025.100551","DOIUrl":"10.1016/j.lansea.2025.100551","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100551"},"PeriodicalIF":5.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143452908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of atrial fibrillation and unmet needs of its management in Southeast Asia and South Asia","authors":"Rungroj Krittayaphong ,&nbsp;Yodying Kaolawanich ,&nbsp;Arintaya Phrommintikul ,&nbsp;Mahesan Guruparan ,&nbsp;Kumaran Subaschandran ,&nbsp;Charantharayil Gopalan Bahuleyan ,&nbsp;Narayanan Namboodiri ,&nbsp;Gregory Y.H. Lip","doi":"10.1016/j.lansea.2025.100549","DOIUrl":"10.1016/j.lansea.2025.100549","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100549"},"PeriodicalIF":5.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143452907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights from ESMO Asia Congress 2024","authors":"Thittayil Suresh Apoorv","doi":"10.1016/j.lansea.2025.100554","DOIUrl":"10.1016/j.lansea.2025.100554","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100554"},"PeriodicalIF":5.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143463844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the cancer epidemic in India: a glimpse into GLOBOCAN 2022 and past patterns","authors":"Khushwant Singh,&nbsp;Ashoo Grover,&nbsp;Kavitha Dhanasekaran","doi":"10.1016/j.lansea.2025.100546","DOIUrl":"10.1016/j.lansea.2025.100546","url":null,"abstract":"<div><h3>Background</h3><div>The Global Cancer Observatory (GLOBOCAN) 2022 estimates highlight cancer as a significant global health problem. In the South-East Asia-region, India ranks third in terms of cancer incidence, second for mortality, and 121 in terms of crude rates globally. As cancer risks increase with age, particularly affecting older individuals, this study explores the current cancer burden in India by analyzing the cancer landscape across different age groups, determining the population's risk of cancer diagnosis and death, and projecting the future cancer burden aligned with past mortality patterns.</div></div><div><h3>Methods</h3><div>This is a comprehensive-retrospective, cross-sectional study examining 36 cancer types, by gender, and across four-distinct age groups (childhood, reproductive, middle age, geriatric) in India, using the GLOBOCAN 2022 database. The study further analyzes the past mortality patterns (2000–2022) and future cancer landscape of India by determining annual percent change (APC), through Multijoinpoint regression analysis.</div></div><div><h3>Findings</h3><div>The five most prevalent cancers affecting both genders collectively account for 44% of cancer burden in India. Notably, females exhibit higher crude incidence (104.5) and crude mortality (64.2) rates compared to males (91.5 and 62.2), based on 0.676 billion females and 0.731 billion males’ populations in 2022. The middle-aged and geriatric-cohorts account the heaviest (70%) cancer burden with higher crude rates (315.9–543.1 incidents, 215.6–407.8 mortalities). Alarmingly, cancer-related mortalities have increased faster among females (1.2–4.4% APC) than males (1.2–2.4% APC) over the past decade, and are expected to continue rising over coming two decades.</div></div><div><h3>Interpretation</h3><div>Approximately three out of every five individuals in India succumb to death following a cancer diagnosis, as per the GLOBOCAN 2022 incidence (1,413,316) to mortality (916,827) ratio. Childhood and reproductive age-group individuals bear the lowest risk of developing (0.12–2.4%) and dying (0.08–1.3%) from cancer compared to their middle-aged and geriatric counterparts, having highest risks of developing (8.3–10.3%) and dying (5.5–7.7%) from cancer. As the population of India transitions from the reproductive age group to the middle age and geriatric age group, the India is anticipated to witness the highest cancer burden of all-time in near future, potentially exacerbated by the looming epidemic.</div></div><div><h3>Funding</h3><div>No funding received.</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100546"},"PeriodicalIF":5.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143452910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in female breast cancer among adolescent and young adults in Southeast Asia","authors":"Jenny Chen ,&nbsp;Frances Dominique V. Ho ,&nbsp;Erin Jay G. Feliciano ,&nbsp;James Fan Wu ,&nbsp;Kara Magsanoc-Alikpala ,&nbsp;Edward Christopher Dee","doi":"10.1016/j.lansea.2025.100545","DOIUrl":"10.1016/j.lansea.2025.100545","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100545"},"PeriodicalIF":5.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometriosis and adenomyosis research priorities in India and Sri Lanka: a call for regional collaboration","authors":"Hrishikesh Munshi ,&nbsp;Indunil Piyadigama ,&nbsp;Hemantha Senanayake ,&nbsp;Rahul K. Gajbhiye","doi":"10.1016/j.lansea.2025.100547","DOIUrl":"10.1016/j.lansea.2025.100547","url":null,"abstract":"<div><div>Endometriosis and adenomyosis are major gynaecological conditions affecting women of reproductive age-group, particularly in low- and middle-income countries. This Health Policy outlined research priorities for India and Sri Lanka, derived from a structured debate during the ‘Future Directions in Endometriosis and Adenomyosis Research’ workshop. Researchers from both countries emphasise the need for nationally representative data, improved diagnostic tools, and comprehensive care models. Shared priorities include developing patient registries and improving healthcare access. India focuses on multidisciplinary care centres, advanced diagnostic research, and public education, while Sri Lanka highlights integrating traditional medicine and assessing economic impacts. Both countries prioritise non-invasive diagnostics to address diagnostic delays and healthcare limitations. Establishing patient registries and consortiums for large-scale studies could inform healthcare strategies. Collaborative research among Asian countries could generate tailored regional solutions. Coupled with a strong political will, and adequate funding, the initiative can potentially improve diagnosis, treatment, and quality of life for affected women.</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100547"},"PeriodicalIF":5.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Language as a catalyst for success: a blueprint for standardized terminology and multilingual health literacy in Pakistan","authors":"Humza Irfan ,&nbsp;Areeb Farooq ,&nbsp;Mohammad Usama Toseef","doi":"10.1016/j.lansea.2025.100544","DOIUrl":"10.1016/j.lansea.2025.100544","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100544"},"PeriodicalIF":5.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143402031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Access to timely cancer treatment initiation in India: extent, determinants and trends” [The Lancet Regional Health – Southeast Asia, Volume 32, January 2025, 100514]","authors":"Pritam Halder ,&nbsp;Jyoti Dixit ,&nbsp;Nidhi Gupta ,&nbsp;Nikita Mehra ,&nbsp;Ashish Singh ,&nbsp;Pankaj Malhotra ,&nbsp;Anisha Mathew ,&nbsp;Lalit Kumar ,&nbsp;Amal Chandra Kataki ,&nbsp;Sudeep Gupta ,&nbsp;Shankar Prinja","doi":"10.1016/j.lansea.2025.100543","DOIUrl":"10.1016/j.lansea.2025.100543","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100543"},"PeriodicalIF":5.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143378328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes among HIV positive babies below 18 months of age, diagnosed under the Early Infant Diagnosis (EID) programme, India: a mixed-methods study","authors":"Suchit Kamble ,&nbsp;Nilesh Gawde ,&nbsp;Shilpa Bembalkar ,&nbsp;Noopur Goel ,&nbsp;Mohan Thorwat ,&nbsp;Kalyani Nikhare ,&nbsp;Sushmita Kamble ,&nbsp;Radhika Brahme ,&nbsp;Swapna Pawar ,&nbsp;Harsh Kubavat ,&nbsp;Bhawanisingh Kushwaha ,&nbsp;Vinita Verma ,&nbsp;Chinmoyee Das ,&nbsp;Raman Gangakhedkar","doi":"10.1016/j.lansea.2025.100540","DOIUrl":"10.1016/j.lansea.2025.100540","url":null,"abstract":"<div><h3>Background</h3><div>Early Anti-Retroviral Therapy (ART) initiation among infants with perinatally acquired HIV is known to impact clinical outcomes and survival. Early Infant Diagnosis (EID) was initiated in programme settings in India in 2010. Its impact on the clinical outcomes of infants covered under the programme and associated determinants have not been reported.</div></div><div><h3>Methods</h3><div>This was a mixed-methods study. Quantitative clinical data of 310 children on ART with HIV diagnosis before 18 months of age was collected from the treatment cards across 30 ART centres from 11 states of India using a retrospective cohort design. A total of 67 In-depth interviews with healthcare providers and managers helped to understand the underlying causes.</div></div><div><h3>Findings</h3><div>Out of 310 infants, 200 (64.5%) were on ART, and 36 (11.6%) were lost to follow-up, and 25 (8.1%) had died. The median age at HIV diagnosis was 231.5 (130, 405) days, and the median age at ART initiation was 309 (198, 456) days. Three-year survival was 91%. Baseline CD4 count less than 1500 cells/mm³ had a higher hazard for mortality (hazard ratio 11.39 (CI: 1.45, 89.45), p = 0.021) as well as for either mortality or development of opportunistic infections (hazard ratio 4.87 (CI: 1.56, 15.15), p = 0.006). WHO clinical stages III and IV had hazard ratios of 2.42 ((CI: 1.43, 4.09), p = 0.001) for mortality and 1.92 ((CI: 1.28, 2.88), p = 0.001) for death or development of opportunistic infections. Demand-side issues such as stigma and discrimination at family, community, and societal levels, desperation about the survival of the child, supply-side factors such as remote access to paediatric ART centres, and lack of paediatric ART medicine formulations were associated with ART treatment.</div></div><div><h3>Interpretation</h3><div>Overall survival was good for those who continued on treatment, but mortality was high for those with poor immunological and clinical parameters. Retention in care needs to be ensured for better clinical outcomes.</div></div><div><h3>Funding</h3><div>The study was commissioned by the National AIDS Control Programme (T.11020/98/2014-NACO (R&amp;D)) and funded through The <span>Global Fund Against AIDS, TB and Malaria (GFATM)</span> grant.</div></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":"34 ","pages":"Article 100540"},"PeriodicalIF":5.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143197124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}