The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)最新文献

Biomimetic Mineralisation - Nature-inspired Strategy for Promising Hard Tissue Regenerative Materials Development. 仿生矿化——受自然启发的硬组织再生材料开发策略。

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The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-09-26 DOI: 10.3290/j.cjdr.b6553419

Lin Xue Zhang, Zuo Ying Yuan, Yu Ming Zhao, Yun Fan Zhang

{"title":"Biomimetic Mineralisation - Nature-inspired Strategy for Promising Hard Tissue Regenerative Materials Development.","authors":"Lin Xue Zhang, Zuo Ying Yuan, Yu Ming Zhao, Yun Fan Zhang","doi":"10.3290/j.cjdr.b6553419","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6553419","url":null,"abstract":"Biomineralisation is a remarkable biological process in which living organisms exert precise control over the nucleation and growth of inorganic crystalline phases, resulting in the formation of hierarchically structured biocomposites that exhibit exceptional mechanical and functional properties. Since damage to bone and teeth directly affect everyday life, various biomimetic mineralised materials have been engineered for use in biomedical applications. While bioinspired materials typically demonstrate superior mechanical properties and biological functions, significant disparities remain between biomimetic constructs and their natural counterparts, especially concerning mechanical performance and multiscale structural organisation. This review initially describes the dynamic reciprocity between type I collagen fibrils, amorphous calcium phosphate phases and multifunctional non-collagenous protein within mineralisation microenvironments. Furthermore, it evaluates recent progress in advanced biomaterials based on biomimetic mineralisation strategies and seeks to spark innovative and promising solutions for investigators exploring biomineralisation principles in regenerative medicine and hard tissue reconstruction. Existing problems and future directions are discussed.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 3","pages":"163-172"},"PeriodicalIF":0.9,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and Morphological Characteristics of Canalis Sinuosus in Unilateral and Bilateral Cleft Lip and Palate Patients and Normal Controls. 单侧和双侧唇腭裂患者及正常人鼻窦管的患病率及形态特征。

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The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-09-26 DOI: 10.3290/j.cjdr.b6553453

Maryam Paknahad, Mina Atazadeh

{"title":"Prevalence and Morphological Characteristics of Canalis Sinuosus in Unilateral and Bilateral Cleft Lip and Palate Patients and Normal Controls.","authors":"Maryam Paknahad, Mina Atazadeh","doi":"10.3290/j.cjdr.b6553453","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6553453","url":null,"abstract":"Objective: To compare the prevalence and morphological characteristics of canalis sinuosus (CS) between unilateral cleft lip and palate (UCLP), bilateral cleft lip and palate (BCLP) and control groups.Methods: The sample consisted of 238 CBCT images (476 sides) from 98 UCLP subjects (196 sides), 36 BCLP subjects (72 sides) and 104 healthy controls (208 sides). Recorded parameters included prevalence of CS, diameter, location of the teeth and adjacent structures. Afterwards, the recorded parameters were compared between the UCLP, BCLP and control groups.Results: The prevalence of CS in the control, UCLP and BCLP groups showed significant differences. The BCLP group revealed a significantly lower prevalence of CS than the UCLP and control groups. There was a considerable increase in CS diameter in the CLP groups compared with the control group. The terminal location of CS was in the canine region for the CLP groups and in the lateral incisor region for the control group. CLP had a significant impact on the location of the end of the CS. CEJB (cementoenamel junction buccal) and CEJL (cementoenamel junction lingual) measurements showed significant differences between the CLP cases and control groups.Conclusion: Different characteristics was revealed between the control, UCLP and BCLP groups. Assessment of CS in patients with CLP with CBCT images is crucial before performing surgical procedures.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 3","pages":"219-224"},"PeriodicalIF":0.9,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of Depth and Choice of Operating Instruments on the Precision of Dynamic Navigation Systems. 深度和操作仪器的选择对动态导航系统精度的影响。

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The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-09-26 DOI: 10.3290/j.cjdr.b6553449

Xiao Xiang Huang, Ding Xiang Yuan, Ben Xiang Hou

{"title":"Influence of Depth and Choice of Operating Instruments on the Precision of Dynamic Navigation Systems.","authors":"Xiao Xiang Huang, Ding Xiang Yuan, Ben Xiang Hou","doi":"10.3290/j.cjdr.b6553449","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6553449","url":null,"abstract":"Objective: To evaluate the precision and efficiency of dynamic navigation-assisted trephines and fissure drills at varying depths utilising a 3D printed model.Methods: A computer-designed in vitro standardised model was 3D printed using photosensitive resin, with hemispherical cavities reserved at depths of 5, 10 and 15 mm from the outer surface of the model. CBCT scans were taken before the procedure, and the data were imported into dynamic navigation software. Navigation paths were planned and executed using a trephine with a diameter of 4 mm and a fissure drill with a diameter of 1.2 mm guided by the dynamic navigation system. Ten procedures were performed at each depth. Postoperative CBCT scans were taken to reconstruct the navigated trajectories, and the platform deviations, end deviations and angular deviations were calculated by comparing the actual paths with the planned paths. The operating time was recorded.Results: Under the guidance of the dynamic navigation system, the mean platform, end and angular deviations for trephines were 0.34 ± 0.17 mm, 0.25 ± 0.15 mm and 1.02 ± 0.49 degrees, respectively. For fissure drills, the mean deviations were 0.29 ± 0.13 mm, 0.31 ± 0.18 mm, and 1.33 ± 0.98 degrees, respectively. No significant differences were found with different depths or instrument types (P > 0.05). High-speed handpieces with fissure drills showed superior efficiency to low-speed handpieces with trephines (P < 0.001).Conclusion: Dynamic navigation technology achieved good accuracy within a 15-mm depth range. The use of a trephine or fissure drill did not affect the accuracy of the dynamic navigation technique. High-speed handpieces with fissure drills showed superior efficiency.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 3","pages":"209-217"},"PeriodicalIF":0.9,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between Periodontitis and Systemic Diseases: Results from the 4th National Oral Health Survey in China. 牙周炎与全身性疾病的关系：第四次全国口腔健康调查结果

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The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-09-26 DOI: 10.3290/j.cjdr.b6553442

Ya Lin Zhan, Jian Jiao, Wu Di Jing, Xi Ping Feng, Bao Jun Tai, De Yu Hu, Huan Cai Lin, Bo Wang, Chun Xiao Wang, Shu Guo Zheng, Xue Nan Liu, Wen Sheng Rong, Wei Jian Wang, Xing Wang, Yan Si, Huan Xin Meng

{"title":"Association between Periodontitis and Systemic Diseases: Results from the 4th National Oral Health Survey in China.","authors":"Ya Lin Zhan, Jian Jiao, Wu Di Jing, Xi Ping Feng, Bao Jun Tai, De Yu Hu, Huan Cai Lin, Bo Wang, Chun Xiao Wang, Shu Guo Zheng, Xue Nan Liu, Wen Sheng Rong, Wei Jian Wang, Xing Wang, Yan Si, Huan Xin Meng","doi":"10.3290/j.cjdr.b6553442","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6553442","url":null,"abstract":"Objective: To evaluate the association between systemic diseases and severity of periodontitis based on Chinese epidemiological data.Methods: Data of dentate subjects (35- to 44-year-old group, 55- to 64-year-old group, and 65- to 74-year-old group) from the Fourth National Oral Health Survey of China were analyzed. Selfreport diagnosis of systemic diseases was based on face-to-face interview. Periodontal status was defined by the 2018 classification scheme and periodontal parameters including bleeding on probing (BOP), probing depth (PD) and attachment loss (AL).Results: The prevalence of systemic diseases, was much higher in subjects with advanced periodontitis but similar in subjects with other periodontal status. The association between systemic diseases and advanced periodontitis is stronger in the younger adult group but weakens with age.Conclusion: Periodontitis is a significant associated with systemic diseases, especially hypertension, heart disease, diabetes among Chinese adults based on the data of the Fourth National Oral Health Survey of China. In view of the worsening health burden of periodontitis, it might be necessary for healthcare providers to be more concerned about prevention and treatment of periodontitis in order to enhance systemic health.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 3","pages":"197-207"},"PeriodicalIF":0.9,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-surgical Management of a Facial Sinus Tract Originated from the Maxillary First Molar Periapical Infection: a Case Report. 上颌第一磨牙根尖周感染所致面窦道的非手术治疗1例。

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The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-09-26 DOI: 10.3290/j.cjdr.b6553458

Yu Han Wang, Zu Hua Wang, Xiao Yan Wang

引用次数: 0

miR-192-5p Inhibits Osteo-/odontogenic Differentiation in Dental Pulp Stem Cells by Targeting COL5A1. miR-192-5p通过靶向COL5A1抑制牙髓干细胞成骨/牙源性分化

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The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-09-26 DOI: 10.3290/j.cjdr.b6553436

Zi Yan Sun, Yi Jie Zhang, Hao Qing Yang, Hui Na Liu, Dong Mei Yang, Zhi Peng Fan

{"title":"miR-192-5p Inhibits Osteo-/odontogenic Differentiation in Dental Pulp Stem Cells by Targeting COL5A1.","authors":"Zi Yan Sun, Yi Jie Zhang, Hao Qing Yang, Hui Na Liu, Dong Mei Yang, Zhi Peng Fan","doi":"10.3290/j.cjdr.b6553436","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6553436","url":null,"abstract":"Objective: To investigate the biological function of miR-192-5p in osteogenic and odontogenic differentiation of dental pulp stem cells (DPSCs).Methods: Alkaline phosphatase (ALP) activity assay, Alizarin Red S (ARS) staining and western blot analysis were applied to investigate the osteogenic differentiation potential of DPSCs in vitro. The osteogenic capacity was estimated by subcutaneous transplantation in nude mice in vivo. Carboxyfluorescein diacetate, succinimidyl ester (CFSE) assay was used to examine cell proliferation. Bioinformatics analyses, dual-luciferase reporter assays and real-time reverse transcriptase-polymerase chain reactions (RT-PCR) were applied to explore the regulatory mechanism of miR-192-5p.Results: miR-192-5p decreased the ALP activity, nodule mineralisation and expression of BSP and OCN in DPSCs, and inhibited cell proliferation. Conversely, the miR-192-5p inhibitor motivated the osteogenic and odontogenic differentiation of DPSCs both in vitro and in vivo, along with promoting cell proliferation. COL5A1 was recognised as the target gene of miR-192- 5p through bioinformatics analysis. Furthermore, dual luciferase reporter assays and RT-PCR experiments confirmed this interaction. Subsequent research verified that COL5A1 knockdown negatively affects the osteo-/odontogenic differentiation of DPSCs, with the PI3K/AKT signalling pathway involved in this process. COL5A1 knockdown promoted the proliferation of DPSCs.Conclusion: miR-192-5p suppressed osteo/odontogenic differentiation by targeting COL5A1 in DPSCs and negatively regulated their proliferation. Conversely, COL5A1 knockdown promoted proliferation.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 3","pages":"185-195"},"PeriodicalIF":0.9,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Periodontitis-induced Systemic Multi-organ Aging Mediated by the NF-κB Signalling Pathway. NF-κB信号通路介导的牙周炎诱导的全身多器官衰老。

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The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-09-26 DOI: 10.3290/j.cjdr.b6553426

Sheng Chen Lo, Yi Fan Wang, Xu Liang Deng

{"title":"Periodontitis-induced Systemic Multi-organ Aging Mediated by the NF-κB Signalling Pathway.","authors":"Sheng Chen Lo, Yi Fan Wang, Xu Liang Deng","doi":"10.3290/j.cjdr.b6553426","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6553426","url":null,"abstract":"Objective: To investigate the causal role of periodontitis in inducing distal-organ aging and elucidate the mechanism between periodontitis and multi-organ aging by assessing the role of NF-κB signalling in mediating cellular senescence.Methods: A ligature-induced periodontitis mouse model was established to systematically examine the expression profiles of senescence markers, including senescence-associated secretory phenotype (SASP) regulatory genes (Il1b, Il6, Mmp13), telomere length, and cellular senescence markers (p16^INK4a, p21^CIP1/WAF1 and β-galactosidase) in peripheral blood, bone marrow, aorta, heart, thymus and uterus. To further clarify the mediating role of the NF-κB signalling pathway in periodontitis-induced multi-organ aging, an intervention study was conducted using the specific NF-κB inhibitor BAY 11-7082.Results: The results revealed significantly elevated expression of SASP-related genes in the peripheral blood of periodontitis mice compared to controls (P < 0.01). Various classic molecular hallmarks of aging, such as upregulated expression of SASP genes, shortened telomeres and increased p16 expression, were also observed in multiple distal organs/tissues. Further mechanistic studies revealed that selective inhibition of the NF-κB signalling pathway significantly attenuated the expression of these aging phenotypic markers (P < 0.01), indicating that this pathway plays a critical role in mediating periodontitis-induced systemic aging.Conclusion: This study provides direct experimental evidence that periodontitis can promote systemic multi-organ aging via activation of the NF-κB signalling pathway, establishing a theoretical basis for developing therapeutic interventions.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 3","pages":"173-184"},"PeriodicalIF":0.9,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A New Classification System for Alveolar Bone Morphology around Maxillary Incisors in Adult Patients with Maxillary Protrusion. 成人上颌前突患者上颌切牙周围牙槽骨形态的新分类系统。

The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-06-11 DOI: 10.3290/j.cjdr.b6260618

Qian Yi Qin, Yun Fei Zheng, Yi Ping Huang, Yi Fan Lin, Run Zhi Guo, Wei Ran Li

{"title":"A New Classification System for Alveolar Bone Morphology around Maxillary Incisors in Adult Patients with Maxillary Protrusion.","authors":"Qian Yi Qin, Yun Fei Zheng, Yi Ping Huang, Yi Fan Lin, Run Zhi Guo, Wei Ran Li","doi":"10.3290/j.cjdr.b6260618","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6260618","url":null,"abstract":"Objective: To develop a new alveolar bone morphology classification for maxillary incisors in patients with maxillary protrusion, and to investigate the association of alveolar morphology with skeletal patterns and alveolar bone defects following retraction.Methods: A retrospective study of CBCT scans was performed for 250 patients with maxillary protrusion. The morphology of alveolar bone around maxillary incisors was classified into four types: A1 (upright maxillary incisor in thin alveolar bone), A2 (lingually inclined maxillary incisor in thin alveolar bone), B1 (upright maxillary incisor in thick alveolar bone) and B2 (lingually inclined maxillary incisor in thick alveolar bone). The association of alveolar types with different skeletal patterns and the incidence of post-treatment alveolar bone defects were analysed.Results: For maxillary incisors in patients with maxillary protrusion, A1 was the most common alveolar type (33.4%), followed by A2 (28.5%), B1 (22.1%) and B2 (16.0%). Types B1 (34.4%) and A2 (42.2%) were the most common in maxillary central and lateral incisors, respectively. In high angle patients, A2 and A1 were the most common types for maxillary lateral (49.6%) and central incisors (41.2%), respectively. Additionally, types A1 and A2 were at greater risk of severe lingual dehiscence.Conclusion: This is the first alveolar bone morphology classification for maxillary incisors in patients with maxillary protrusion. The alveolar types exhibited a significant association with skeletal patterns and the incidence of alveolar bone defects after retraction.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 2","pages":"123-129"},"PeriodicalIF":0.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Periodontitis Exacerbates Cognitive Impairment via Endothelial Inflammation: Insights from Single-Nucleus Transcriptomics. 牙周炎通过内皮炎症加剧认知障碍：来自单核转录组学的见解。

The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-06-11 DOI: 10.3290/j.cjdr.b6260577

Zong Shan Shen, Ji Chen Yang, Chuan Jiang Zhao, Bin Cheng

{"title":"Periodontitis Exacerbates Cognitive Impairment via Endothelial Inflammation: Insights from Single-Nucleus Transcriptomics.","authors":"Zong Shan Shen, Ji Chen Yang, Chuan Jiang Zhao, Bin Cheng","doi":"10.3290/j.cjdr.b6260577","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6260577","url":null,"abstract":"Objective: To explore the underlying mechanisms of the association between periodontitis and cognitive impairment.Methods: Single-nucleus transcriptomics of mice were used to investigate the impact of periodontitis on brain and hippocampal cells to gain insights into disease progression. After data processing, functional enrichment, pathway analysis and cell-cell communication analysis were used to identify the distinct pathways and genes upregulated in Alzheimer's disease (AD) linked to periodontitis. After cell culture, real-time quantitative polymerase chain reaction (RT-qPCR) and enzyme-linked immunosorbent assay (ELISA) were used to confirm the results.Results: The present authors identified endothelial inflammation as a key factor in periodontitis-related AD. The findings revealed that the upregulation of Mgll expression in endothelial cells was linked to increased antigen presentation and exacerbated neuroinflammation, potentially worsening AD. Moreover, the present authors elucidated MGLL-2AG-CB2 signalling, through which MGLL activation suppresses CB2 expression and leads to heightened inflammation, while MGLL inhibition restores CB2 levels and mitigates inflammation.Conclusion: The present study revealed the role of MGLL in linking periodontitis to hippocampal endothelial inflammation and antigen presentation in cognitive impairment. This research will enhance the understanding of how periodontitis impacts cognition and explore potential therapeutic strategies to alleviate periodontitis-associated cognitive impairment.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 2","pages":"105-114"},"PeriodicalIF":0.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Periapical Healing Outcomes of Single-visit Non-surgical Endodontic Retreatment of Teeth with Apical Periodontitis in Patients with Type 2 Diabetes Mellitus: a Retrospective Study. 2型糖尿病根尖牙周炎患者单次非手术牙髓再治疗根尖周愈合效果的回顾性研究。

The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) Pub Date : 2025-06-11 DOI: 10.3290/j.cjdr.b6260628

Merve Işik, Tülin Doğan Çankaya, Zeliha Uğur Aydin

{"title":"Evaluation of Periapical Healing Outcomes of Single-visit Non-surgical Endodontic Retreatment of Teeth with Apical Periodontitis in Patients with Type 2 Diabetes Mellitus: a Retrospective Study.","authors":"Merve Işik, Tülin Doğan Çankaya, Zeliha Uğur Aydin","doi":"10.3290/j.cjdr.b6260628","DOIUrl":"https://doi.org/10.3290/j.cjdr.b6260628","url":null,"abstract":"Objective: To compare the results of non-surgical endodontic retreatment (NSER) applied in a single visit between type 2 diabetes mellitus (DM) patients with teeth with apical periodontitis (AP) and healthy individuals.Methods: The subjects enrolled were divided into two groups. The type 2 DM group was composed of 26 single-rooted mandibular teeth belonging to 26 patients (aged 45.04 ± 10.13 years; 19 women and 7 men) who did not have any other systemic disease. The control group, meanwhile, consisted of 27 single-rooted mandibular teeth from 27 patients (aged 37.78 ± 12.61 years; 15 women and 12 men) with no systemic disease. Both groups received single-visit non-surgical endodontic retreatment. Periapical radiographs were taken with a parallel technique before NSER and at least 6 months after treatment. Periapical index scores (PAI) for the relevant teeth were recorded. The data obtained were analysed statistically. P 0.05 was considered significant.Results: In both groups, postoperative PAI values decreased compared to the initial values after NSER treatment applied in a single visit (P 0.05); however, there was no significant difference in the change in PAI values over time between the control and type 2 DM groups (P > 0.05). There was also no significant difference in healing between men and women in both groups (P > 0.05).Conclusion: Following single-visit NSER in teeth with apical periodontitis, similar treatment outcomes were achieved in patients with type 2 DM and healthy individuals.","PeriodicalId":74983,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA)","volume":"28 2","pages":"139-146"},"PeriodicalIF":0.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0