Advances in Skin & Wound Care最新文献

The Approximation Principle: A Novel Mechanobiological Approach to Chronic Wound Management. 近似原理：慢性伤口处理的一种新的机械生物学方法。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-04-17 DOI: 10.1097/ASW.0000000000000432

Igor Melnychuk, Fateme Fayyazbakhsh

{"title":"The Approximation Principle: A Novel Mechanobiological Approach to Chronic Wound Management.","authors":"Igor Melnychuk, Fateme Fayyazbakhsh","doi":"10.1097/ASW.0000000000000432","DOIUrl":"https://doi.org/10.1097/ASW.0000000000000432","url":null,"abstract":"Chronic wounds represent a pathological disruption of the canonical wound healing cascade, often arrested in a pro-inflammatory phase due to cellular senescence, biofilm presence, and altered mechanotransduction signaling. Approximation in wound care refers to the process of bringing the wound's opposing tissue surfaces, either edges or walls, closer together to facilitate faster healing. Though common in acute wound closure, the approximation principle is rarely used in chronic wounds due to concerns about cavity formation and infection. This paper redefines approximation as a biomechanical intervention targeting wound wall convergence to converge wound walls through controlled compression. Unlike edge-based suturing or closure, wall approximation modifies the wound's 3D architecture and microenvironment, thus stimulating tissue regeneration. Mechanical compression influences fibroblast behavior and matrix remodeling through core mechanotransduction pathways involving integrins, cytoskeletal dynamics, and focal adhesion signaling. This study investigates the influence of skin anisotropy and Langer's lines on modulating mechanical tension and healing outcome. Integrating clinical observations with mechanistic insights, this article presents approximation as a practical, evidence-based strategy to promote healing in chronic wounds, including those not amenable to surgical closure.","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"39 4","pages":"175-179"},"PeriodicalIF":1.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developing Consensus Wound Care Research Priorities Among Stakeholders in Canada: A Mixed-Methods Study. 在加拿大利益相关者中发展共识伤口护理研究优先事项：一项混合方法研究。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-03-27 DOI: 10.1097/ASW.0000000000000431

Omar Gaballa, Virginie Blanchette, Leslie Summers deLuca, Ahmed Kayssi

{"title":"Developing Consensus Wound Care Research Priorities Among Stakeholders in Canada: A Mixed-Methods Study.","authors":"Omar Gaballa, Virginie Blanchette, Leslie Summers deLuca, Ahmed Kayssi","doi":"10.1097/ASW.0000000000000431","DOIUrl":"10.1097/ASW.0000000000000431","url":null,"abstract":"Objective: The purpose of this work was to identify consensus wound care research priorities in Canada.Methods: A sequential mixed-methods approach utilizing a national survey followed by a modified Delphi technique was used to identify consensus research priorities. The modified Delphi process included 3 rounds of voting and 2 virtual workshops for stakeholder discussions. Stakeholders from the wound care community included patients, caregivers, clinicians of various backgrounds, researchers, industry partners, and Wounds Canada leaders.Results: The first Canada-wide survey was completed by 91 respondents (75 English-speaking and 16 French-speaking). Respondents submitted 161 priority research questions that were edited for clarity and redundancy, resulting in 112 questions. Twenty-nine expert panelists participated in the Delphi process. Three anonymous panelist questionnaires and 2 remote workshops were carried out to generate 29 wound care research priorities. All questions were reviewed and rated by the panelists, with 23 questions ultimately meeting the 80% consensus threshold.Conclusions: Stakeholders are motivated to improve wound outcomes through evidence-informed changes and clinical innovations; however, no consensus existed among Canadian wound care stakeholders on research priorities. Through the findings of this work, which identified consensus wound care research priorities, targeted research activities, and strategic planning can be facilitated with a focus on expedited improvements in wound care.","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"208-215"},"PeriodicalIF":1.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147589478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced Home-Based Wart Treatment Protocol: Optimizing Debridement and Occlusion Therapy for Improved Outcomes. 增强的家庭疣治疗方案：优化清创和闭塞治疗以改善结果。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-04-17 DOI: 10.1097/ASW.0000000000000445

引用次数: 0

Learning Modules to Enhance Nursing Education About Assessment of Diverse Skin Tones. 加强不同肤色评估护理教育的学习模块。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-03-23 DOI: 10.1097/ASW.0000000000000430

Linnea Benike, Donna Z Bliss, Cassandra Narr, Olga V Gurvich, Alice Smeltzer, Olivia Stueber, Casey Kirchschlager

{"title":"Learning Modules to Enhance Nursing Education About Assessment of Diverse Skin Tones.","authors":"Linnea Benike, Donna Z Bliss, Cassandra Narr, Olga V Gurvich, Alice Smeltzer, Olivia Stueber, Casey Kirchschlager","doi":"10.1097/ASW.0000000000000430","DOIUrl":"10.1097/ASW.0000000000000430","url":null,"abstract":"Objective: Accurate assessment of skin and skin changes across diverse populations is critical for patient health. To promote the knowledge and skills nurses need in practice to identify skin changes, nurse educators must include content on assessment of diverse skin tones in nursing education programs. This study's objective was to develop and pilot education modules about the assessment of diverse skin tones to be part of an undergraduate nursing course.Methods: In this quality improvement project, modules highlighted the importance of skin assessment and appropriate techniques for assessing erythema, pallor, cyanosis, and jaundice on diverse skin tones. Undergraduate nursing students completed a questionnaire evaluating the modules and their learning experience.Results: The majority of students (≥70%) agreed or highly agreed that the modules were interesting, informative, engaging, and increased their knowledge. Comments to open-ended questions supported their evaluation ratings.Conclusions: Undergraduate nursing students positively received education modules on assessing patients with diverse skin tones. Students perceived the modules as having the potential to enhance their learning and assessment skills to prevent and detect skin changes associated with pressure injury. The modules serve as an example of a strategy to integrate education content about diverse skin tones into nursing curricula.","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"185-193"},"PeriodicalIF":1.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147497264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Microwave Thermotherapy Versus Intralesional Antimonial in the Treatment of Cutaneous Leishmaniasis: A Randomized Clinical Trial. 评价微波热疗法与局灶内注射锑治疗皮肤利什曼病：一项随机临床试验。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-03-23 DOI: 10.1097/ASW.0000000000000437

Masoud Maleki, Naeemeh Ebrahimabadi, Vahid Mashayekhi Goyonlo, Bita Kiafar, Masoumeh Hosseininezhad, Negar Morovatdar, Hossein Hasanabadi, Seyedeh Zahra Ghasemi

{"title":"Evaluation of Microwave Thermotherapy Versus Intralesional Antimonial in the Treatment of Cutaneous Leishmaniasis: A Randomized Clinical Trial.","authors":"Masoud Maleki, Naeemeh Ebrahimabadi, Vahid Mashayekhi Goyonlo, Bita Kiafar, Masoumeh Hosseininezhad, Negar Morovatdar, Hossein Hasanabadi, Seyedeh Zahra Ghasemi","doi":"10.1097/ASW.0000000000000437","DOIUrl":"10.1097/ASW.0000000000000437","url":null,"abstract":"Objective: There is a need for safer and more efficient therapies for cutaneous leishmaniasis (CL). This study evaluates the effectiveness of thermotherapy using microwave in the treatment of cutaneous leishmaniasis alongside intralesional meglumine antimoniate.Methods: This pilot study was conducted among 40 patients with CL using a randomized controlled methodology. Participants were randomly allocated to receive either microwave thermotherapy (intervention; N=20) twice a week or intralesional meglumine antimoniate therapy weekly (control; N=20). The size of the induration of lesions was assessed at the starting point and at 2, 3, 6, and 12 months after treatment. A significance level of P <.05 was determined.Results: The total number of lesions was 55. The rate of complete recovery after 1 year was 55.2% in the intervention group and 76.9% in the control group. There was no statistically significant variation in the remission distribution comparing either of the groups ( P =.155). The complications in the intervention group were markedly reduced compared with the control group ( P =.027).Conclusions: Microwave thermotherapy is an efficient and innovative treatment for CL that does not have any adverse effects. This method can be used as an alternative therapy in certain areas and with certain patients.","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"216-223"},"PeriodicalIF":1.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147497337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combining Acellular Dermal Grafts With Negative-Pressure Wound Therapy in a Postsurgical Wound: A Case Report. 脱细胞真皮移植联合负压创面治疗术后创面1例。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-03-24 DOI: 10.1097/ASW.0000000000000435

Fiona S Gruzmark, Robert S Kirsner, Jose A Jaller

引用次数: 0

Wound-QoL Questionnaire: Turkish Validity and Reliability Study. 创伤-生活质量问卷：土耳其语效度与信度研究。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-03-24 DOI: 10.1097/ASW.0000000000000434

Münevver Sönmez, Rabia Koca, Canan Eraydin, Cansu Çirak, Gaye Filinte

{"title":"Wound-QoL Questionnaire: Turkish Validity and Reliability Study.","authors":"Münevver Sönmez, Rabia Koca, Canan Eraydin, Cansu Çirak, Gaye Filinte","doi":"10.1097/ASW.0000000000000434","DOIUrl":"10.1097/ASW.0000000000000434","url":null,"abstract":"Objective: This study aimed to test the validity and reliability of the Turkish version of the Wound-QoL Questionnaire, developed to assess the quality of life of individuals with chronic wounds.Methods: This methodological study included 146 patients with chronic wounds who met the inclusion criteria. Research data were collected using the Patient Information Form and the Wound-QoL Questionnaire.Results: Exploratory factor analysis (EFA) led to the removal of item 17 due to a factor loading <0.4, and items 4 and 16 due to differences below 0.1 between factor loadings. The final EFA indicated a 3-factor structure explaining 75.03% of total variance. Confirmatory factor analysis results showed excellent fit indices: χ²/ df =0.528, RMSEA=0.000, CFI=1.000, AGFI=0.931, NFI=1.000, TLI=1.000, IFI=1.000; and acceptable fit indices: SRMR=0.093, GFI=0.951. The total Cronbach α coefficient was 0.92. Test-retest analysis with 60 patients revealed no statistically significant differences between subdimension and total scores, with strong correlations between the 2 measurements ( P <.001).Conclusions: The Turkish version of the Wound-QoL Questionnaire is a valid and reliable tool for assessing the quality of life of individuals with chronic wounds.","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E167-E173"},"PeriodicalIF":1.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147589421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and Safety of Topical Use of Sevoflurane as a Local Analgesic in Wounds: A Systematic Review. 局部使用七氟醚作为伤口局部镇痛药的有效性和安全性：系统综述。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-03-24 DOI: 10.1097/ASW.0000000000000424

Pere Coca-Alves, Joan Enric Torra-Bou, Joan Blanco-Blanco

{"title":"Efficacy and Safety of Topical Use of Sevoflurane as a Local Analgesic in Wounds: A Systematic Review.","authors":"Pere Coca-Alves, Joan Enric Torra-Bou, Joan Blanco-Blanco","doi":"10.1097/ASW.0000000000000424","DOIUrl":"10.1097/ASW.0000000000000424","url":null,"abstract":"Objective: Local management of chronic or difficult-to-heal wounds often involves pain. Effective pain management remains challenging for practitioners, as existing treatments may fall short in providing comprehensive relief. Sevoflurane has emerged as a potential local analgesic in wound care. This systematic review sought to evaluate the safety and efficacy of using sevoflurane as a local analgesic for managing pain in chronic or hard-to-heal wounds.Data sources: The search encompassed PubMed, Scopus, SciELO, and Cochrane databases.Study selection: Inclusion criteria: Studies evaluating the efficacy of sevoflurane as a local analgesic treatment for chronic wounds of any etiology, and research investigating the safety of such treatment. Exclusion criteria: Studies duplicating efficacy and safety outcomes already reported in previous research and grey literature.Data extraction: Following PRISMA guidelines, a comprehensive search across major databases yielded 210 publications as of November 10, 2024, of which 21 were selected for analysis. These encompassed various study types, including clinical cases, cohort studies, clinical trials, and reviews.Data synthesis: All selected studies consistently demonstrate a significant reduction in pain upon application of sevoflurane, with its anesthetic effect manifesting within minutes and lasting for hours. Reported adverse effects are minimal, primarily comprising mild itching and erythema around the wound site.Conclusions: There is a need for further high-quality research to solidify the efficacy and safety of topically administered sevoflurane. This review underscores the potential of sevoflurane as an effective and safe local analgesic in wound management but emphasizes the importance of more robust evidence to support its clinical use.","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E178-E184"},"PeriodicalIF":1.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147589456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Prior Antibiotic Use With Negative Surgical Bone Biopsy Cultures and Disease Recurrence in Diabetes-related Foot Osteomyelitis. 糖尿病相关性足部骨髓炎患者既往抗生素使用与外科骨活检培养阴性和疾病复发的关系

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-02-23 DOI: 10.1097/ASW.0000000000000425

Javier Aragón-Sánchez, Gerardo Víquez-Molina, Javier Aragón-Hernández, José María Rojas-Bonilla

{"title":"Association of Prior Antibiotic Use With Negative Surgical Bone Biopsy Cultures and Disease Recurrence in Diabetes-related Foot Osteomyelitis.","authors":"Javier Aragón-Sánchez, Gerardo Víquez-Molina, Javier Aragón-Hernández, José María Rojas-Bonilla","doi":"10.1097/ASW.0000000000000425","DOIUrl":"10.1097/ASW.0000000000000425","url":null,"abstract":"Objective: The authors hypothesized that prior antibiotic treatment does not reduce culture positivity and that empirical antibiotic therapy in culture-negative cases does not increase the risk of amputation or recurrence in diabetes-related foot osteomyelitis (DFO).Methods: This retrospective study included 100 consecutive patients with DFO treated at La Paloma Hospital, Diabetic Foot Unit, in Las Palmas de Gran Canaria, Spain, from June 1, 2010, to December 1, 2016. Surgical bone biopsies were obtained for microbiological and histologic analysis. Patients were followed for at least 1 year post-wound healing to monitor infection recurrence. Chi-squared and Fisher exact tests were used to analyze associations between antibiotic use, culture results, amputation, and recurrence.Results: Cultures were negative in 28% of cases. No association was found between prior antibiotic use and negative cultures ( P =.443). Amputation rates were similar in patients with positive (31.9%) and negative cultures (32.1%, P =.98). Infection recurrence occurred in 23% of patients, with no significant difference between positive (26.4%) and negative cultures (14.3%, P =.19). Post hoc power analysis showed 79% power to detect differences in infection recurrence.Conclusions: Prior antibiotic use did not significantly impact culture positivity in DFO. Empirical antibiotic therapy in culture-negative cases did not increase the risk of amputation or recurrence. Treatment decisions should be individualized, adhering to antimicrobial stewardship principles. Further studies are needed to clarify the relationship between antibiotic exposure, culture results, and outcomes in DFO.","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E174-E177"},"PeriodicalIF":1.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147269533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of a Skin Tear Virtual Simulation on Wound Care Nurses' Knowledge and Skills. 皮肤撕裂虚拟模拟对伤口护理护士知识和技能的影响。

IF 1.4 4区医学

Advances in Skin & Wound Care Pub Date : 2026-05-01 Epub Date: 2026-03-23 DOI: 10.1097/ASW.0000000000000433

Pelin Karaçay, Vildan Çakar, Şenay Gül, Ayişe Karadağ

{"title":"Effects of a Skin Tear Virtual Simulation on Wound Care Nurses' Knowledge and Skills.","authors":"Pelin Karaçay, Vildan Çakar, Şenay Gül, Ayişe Karadağ","doi":"10.1097/ASW.0000000000000433","DOIUrl":"10.1097/ASW.0000000000000433","url":null,"abstract":"Objective: To develop a virtual simulation for skin tears (STs) and evaluate the effect of this simulation on wound care nurses' knowledge and skill levels.Methods: This study used a pre/post-follow-up design and was conducted in four phases. Researchers developed a virtual simulation on STs (SteVis), the scenario, and the simulation software, and conducted its pilot application within the first 3 stages. In the final stage, researchers evaluated the effect of the SteVis on wound care nurses' knowledge and skill levels. Data were collected using the individual characteristics form, Skin Tear Knowledge Assessment Instrument, skin tear skill assessment form, and SteVis feedback form at 3 time points: before the simulation (T 0 ; n=42), after the simulation (T 1 ; n=42) and at a 2-month follow-up (T 2 ; n=31).Results: Participants' knowledge ( F =7.679; P =.001) and skill scores ( F =20.969; P <.001) regarding STs increased in T 1 and T 2 measurements compared with before the simulation. There was no statistically significant difference in the knowledge scores of the participants between T 1 and T 2 measurements ( P >.05). However, in all measurements, the participants' skill levels increased significantly ( P <.05).Conclusions: The study demonstrated that the use of SteVis increased wound care nurses' knowledge and skill levels regarding STs. Future experimental studies should explore the long-term effects of the SteVis on nurses' knowledge and skill levels.","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"202-207"},"PeriodicalIF":1.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147497306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0