Sensors & diagnostics最新文献_第10页

Red and NIR active dipod–SDS self-assemblies for “turn on” quantification of spermine in serum, urine and food: smart-phone assisted on-site determination of spermine in amine-rich foods† 用于 "开启 "血清、尿液和食品中精胺定量的红色和近红外活性二极体-SDS 自组装：智能手机辅助现场测定富含胺的食品中的精胺

Sensors & diagnostics Pub Date : 2024-05-15 DOI: 10.1039/D3SD00300K

Nancy Singla, Sukhvinder Dhiman, Manzoor Ahmad, Satwinderjeet Kaur, Prabhpreet Singh and Subodh Kumar

{"title":"Red and NIR active dipod–SDS self-assemblies for “turn on” quantification of spermine in serum, urine and food: smart-phone assisted on-site determination of spermine in amine-rich foods†","authors":"Nancy Singla, Sukhvinder Dhiman, Manzoor Ahmad, Satwinderjeet Kaur, Prabhpreet Singh and Subodh Kumar","doi":"10.1039/D3SD00300K","DOIUrl":"10.1039/D3SD00300K","url":null,"abstract":"Spermine is a vital biomarker for clinical diagnosis of cancer and estimating food spoilage. Here, supramolecular assemblies of two donor–π–acceptor dipods R-SPM (λem 640 nm) and NIR-SPM (λem 720 nm) with SDS have been discovered for the detection of spermine and spermidine under physiological conditions at nanomolar levels. The addition of SDS to R-SPM and NIR-SPM results in the formation of self-assemblies (DLS, zeta-potential and UV-vis studies) with no significant change in their fluorescence but further addition of spermine/spermidine to the R-SPM∩SDS and NIR-SPM∩SDS assemblies results in a 30–80 fold increase in fluorescence intensity, respectively at 640 nm and 720 nm. The LOD for spermine and spermidine detection is 22 nM (4.4 ppb) and 67 nM (9.7 ppb). The ensembles show nominal interference from other biogenic amines, amino acids, metal ions, and anions. Both R-SPM∩SDS and NIR-SPM∩SDS ensembles can be stored in the dark for >3 months without affecting their performance. The potential of these ensembles for real world applications like analysis of spermine in urine, human serum and food spoilage in the case of cheese, mushrooms, chicken and mutton has been demonstrated. The smartphone relied RGB analysis facilitates the on-site determination of spermine in food samples.","PeriodicalId":74786,"journal":{"name":"Sensors & diagnostics","volume":" 6","pages":" 1051-1061"},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/sd/d3sd00300k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141063005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of storage conditions on the performance of an electrochemical aptamer-based sensor† 储存条件对基于电化学贴体的传感器性能的影响

Sensors & diagnostics Pub Date : 2024-05-14 DOI: 10.1039/D4SD00066H

Julia Chung, Adriana Billante, Charlotte Flatebo, Kaylyn K. Leung, Julian Gerson, Nicole Emmons, Tod E. Kippin, Lior Sepunaru and Kevin W. Plaxco

引用次数: 0

Correction: Highly sensitive solid-state nanopore aptasensor based on target-induced strand displacement for okadaic acid detection from shellfish samples 更正：基于目标诱导链位移的高灵敏度固态纳米孔准传感器用于检测贝类样品中的冈田酸

Sensors & diagnostics Pub Date : 2024-05-14 DOI: 10.1039/D4SD90015D

Mohamed Amin Elaguech, Yajie Yin, Yunjiao Wang, Bing Shao, Chaker Tlili and Deqiang Wang

引用次数: 0

Aptamer-functionalized nanopipettes: a promising approach for viral fragment detection via ion current rectification† 色素功能化纳米移液管：通过离子电流整流检测病毒片段的有效方法

Sensors & diagnostics Pub Date : 2024-05-10 DOI: 10.1039/D4SD00097H

Shekemi Denuga, Dominik Duleba, Pallavi Dutta, Guerrino Macori, Damion K. Corrigan, Séamus Fanning and Robert P. Johnson

引用次数: 0

Application of breathomics in pediatric asthma: a review 呼吸组学在小儿哮喘中的应用：综述

Sensors & diagnostics Pub Date : 2024-05-09 DOI: 10.1039/D3SD00286A

Lei Chi, Xiaoli Wang, Yuxia Shan, Chonghui Zhu, Ling Leng, Rong Chen, Qing Xie, Zhenze Cui and Minghui Yang

{"title":"Application of breathomics in pediatric asthma: a review","authors":"Lei Chi, Xiaoli Wang, Yuxia Shan, Chonghui Zhu, Ling Leng, Rong Chen, Qing Xie, Zhenze Cui and Minghui Yang","doi":"10.1039/D3SD00286A","DOIUrl":"10.1039/D3SD00286A","url":null,"abstract":"Breathomics involves the use of non-invasive methods for diagnosing asthma by analyzing exhaled breath. While significant progress has been made in applying this approach to adult asthma, extending its application to pediatric asthma is crucial due to the increasing concern in this population. This review delineates five potential clinical applications: asthma diagnosis, differential diagnosis of asthma, assessment of asthma control levels, prediction of asthma exacerbation, and asthma phenotyping. Additionally, it highlights the moderate to reasonable predictive accuracy of exhaled breath volatile organic compounds (VOCs) breathomics in childhood asthma. However, it acknowledges that this field is still in its nascent stage of development, with particularly limited data available for Asian populations. Moreover, the identification of VOC biomarkers in pediatric asthma patients remains inconclusive, with varying reports. Therefore, large-scale data collection and standardization are imperative. Refinement and methodological improvements are necessary before integrating breathomics into clinical practice. This article provides clear directions for future research to optimize the clinical applicability of breathomics in evaluating asthma in children.","PeriodicalId":74786,"journal":{"name":"Sensors & diagnostics","volume":" 6","pages":" 933-945"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/sd/d3sd00286a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140931257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in electrochemical sensors for real-time glucose monitoring 用于实时葡萄糖监测的电化学传感器的进展

Sensors & diagnostics Pub Date : 2024-05-08 DOI: 10.1039/D4SD00086B

Md. Harun-Or-Rashid, Most. Nazmin Aktar, Veronica Preda and Noushin Nasiri

{"title":"Advances in electrochemical sensors for real-time glucose monitoring","authors":"Md. Harun-Or-Rashid, Most. Nazmin Aktar, Veronica Preda and Noushin Nasiri","doi":"10.1039/D4SD00086B","DOIUrl":"10.1039/D4SD00086B","url":null,"abstract":"Technological advancements are revolutionizing diabetic care worldwide, particularly in the realm of glucose monitoring. Traditionally invasive and cumbersome, glucose monitoring is shifting towards less invasive methods, enhancing patient quality of life and reducing risks associated with hypo- and hyperglycemia. Wearable biosensors, focusing on sweat and interstitial fluid, offer novel avenues for early disease detection and personalized point-of-care testing. This review paper provides a comprehensive overview of recent strides in wearable sweat sensors, including historical perspectives, electrochemical sensing mechanisms, material advancements, and the role of nanomaterials in enhancing sensor performance. By examining the evolution of glucose monitoring devices and highlighting commercially available devices, the review underscores the wide-ranging utility of electrochemical sensors in glucose monitoring. Enzymatic and non-enzymatic sensing mechanisms, potentiometric, amperometric/voltammetric sensors, ion-selective electrodes, and biosensors are discussed in detail, alongside various materials employed to optimize sensor performance. The burgeoning interest in nanomaterial-enabled sensor platforms signifies a promising future for sweat-based glucose monitoring, with potential implications for personalized healthcare and disease management.","PeriodicalId":74786,"journal":{"name":"Sensors & diagnostics","volume":" 6","pages":" 893-913"},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/sd/d4sd00086b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140931302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contactless vital sign monitoring systems: a comprehensive survey of remote health sensing for heart rate and respiration in internet of things and sleep applications 非接触式生命体征监测系统：全面调查

IF 3.5

Sensors & diagnostics Pub Date : 2024-05-08 DOI: 10.1039/D4SD00073K

Muhammad Salman Raheel, Faisel Tubbal, Raad Raad, Philip Ogunbona, James Coyte, Christopher Patterson, Dana Perlman, Saeid Iranmanesh, Nidhal Odeh and Javad Foroughi

{"title":"Contactless vital sign monitoring systems: a comprehensive survey of remote health sensing for heart rate and respiration in internet of things and sleep applications","authors":"Muhammad Salman Raheel, Faisel Tubbal, Raad Raad, Philip Ogunbona, James Coyte, Christopher Patterson, Dana Perlman, Saeid Iranmanesh, Nidhal Odeh and Javad Foroughi","doi":"10.1039/D4SD00073K","DOIUrl":"10.1039/D4SD00073K","url":null,"abstract":"With the coronavirus pandemic, companies and governments around the world have been investing millions of dollars in the development of contactless sensor technologies that minimize the need for physical interactions between patients and healthcare providers. This has led to rapid progress in healthcare research on innovative contactless technologies, particularly for infants and elderly individuals with chronic diseases that require continuous, real-time monitoring and control. The combination of sensing technology and wireless communication has emerged as a promising research area, as patients often find it unpleasant or anxiety-provoking to wear sensor devices, and physical contact can exacerbate the spread of contagious diseases. To address these issues, research has focused on sensor-less or contactless technology to send and analyse wireless signals to remotely monitor and measure vital signs without requiring physical contact or sensor devices. Herein, we have provided a comprehensive survey and study of non-invasive/contactless vital sign monitoring systems, particularly the heart rate and the respiration rate monitoring systems to achieve accurate and reliable measurements. We have found that there is a lack of a comprehensive comparison and analysis over existing contactless vital sign monitoring systems. Therefore, we first present and classify the existing non-invasive monitoring designs based on their approaches and techniques, and then compare them based on the performance and accuracy.","PeriodicalId":74786,"journal":{"name":"Sensors & diagnostics","volume":" 7","pages":" 1085-1118"},"PeriodicalIF":3.5,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/sd/d4sd00073k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140931263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical immunomagnetic assay for interleukin-6 detection in human plasma 用于检测人体血浆中白细胞介素-6 的电化学免疫磁分析法

Sensors & diagnostics Pub Date : 2024-05-08 DOI: 10.1039/D4SD00058G

Grace Buckey, Olivia E. Owens, Hannah A. Richards and David E. Cliffel

引用次数: 0

Recent developments in pyrene-based fluorescence recognition and imaging of Ag+ and Pb2+ ions: Synthesis, applications and challenges 基于芘的 Ag+ 和 Pb2+ 离子荧光识别和成像的最新进展：合成、应用与挑战

Sensors & diagnostics Pub Date : 2024-05-07 DOI: 10.1039/D3SD00289F

Suvendu Paul, Prasenjit Barman, Nilanjan Dey and Michael Watkinson

{"title":"Recent developments in pyrene-based fluorescence recognition and imaging of Ag+ and Pb2+ ions: Synthesis, applications and challenges","authors":"Suvendu Paul, Prasenjit Barman, Nilanjan Dey and Michael Watkinson","doi":"10.1039/D3SD00289F","DOIUrl":"10.1039/D3SD00289F","url":null,"abstract":"Contamination of heavy metals in the environment is a burning and contemporary issue of modern life. Whilst lead contamination is historic, the ongoing extensive use of lead in batteries is likely to continue to cause serious environmental problems. Silver ions also present multiple environmental issues, such as bioaccumulation and toxicity. As a result, these two heavy metal ions have a high impact from an environmental and industrial point of view. Thus, the colorimetric and fluorescence detection of these two metal ions has been the subject of intense research during the last decade and pyrene-based fluorophores have played a crucial role in their detection. This review article summarizes the recent chronological progress on pyrene moiety integrated small molecule chemosensors for the colorimetric and fluorescent detection of silver and lead ions. Herein, the different strategies that have been utilized for the recognition of lead and silver ions are discussed. Throughout, the juxtaposition of structural aspects of the chemosensors and their sensitivity has been scrutinized together with an overview and future vision.","PeriodicalId":74786,"journal":{"name":"Sensors & diagnostics","volume":" 6","pages":" 946-967"},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/sd/d3sd00289f?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140931262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydroxypyridinone based chelators: a molecular tool for fluorescence sensing and sensitization 基于羟基吡啶酮的螯合剂：荧光传感和敏化的分子工具

Sensors & diagnostics Pub Date : 2024-05-06 DOI: 10.1039/D3SD00346A

Shalini Singh, Neha Kumari, B. K. Kanungo and Minati Baral

{"title":"Hydroxypyridinone based chelators: a molecular tool for fluorescence sensing and sensitization","authors":"Shalini Singh, Neha Kumari, B. K. Kanungo and Minati Baral","doi":"10.1039/D3SD00346A","DOIUrl":"10.1039/D3SD00346A","url":null,"abstract":"Among the currently developed analytical tools, sensors based on fluorescence detection have received immense recognition owing to their high sensitivity, low cost, fast response, and simplicity. The design and synthesis of fluorescence chemosensors to sense metals that are of environmental and biological relevance are of appreciable interest. The efficacy of fluorescent sensors relies on two crucial features: a metal binding unit and a fluorophore that can absorb and emit light. The electronic structure of the sensor is altered upon complexation, leading to a change in light emission or absorption intensity and wavelength. Hydroxypyridinones, a class of N-heterocyclic metal chelators, are appreciated as magnificent chemical tools in metal chelation with a higher affinity towards hard metals, displaying various medical, biological, and industrial applications. However, such compounds are scarcely used as sensors. This article outlines the recent invention of fluorescence chemosensors related to hydroxypyridinone based chelators for the selective sensing of analytes of biological and environmental importance. This discussion involves the structural parameters, coordination mode, and other approaches that helped develop highly selective fluorescence sensors for the ions. In addition, the luminescence properties of the hydroxypyridinones in the energy transfer process of lanthanide chelates as sensitizers are determined.","PeriodicalId":74786,"journal":{"name":"Sensors & diagnostics","volume":" 6","pages":" 968-986"},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/sd/d3sd00346a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140941930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0